Standout Papers
Citation Impact
Citing Papers
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
2008 StandoutScienceNobel
A Genomic Map of p53 Binding Sites Identifies Novel p53 Targets Involved in an Apoptotic Network
2005
Erasure of CpG methylation in Arabidopsis alters patterns of histone H3 methylation in heterochromatin
2003
Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2
2003 StandoutScience
Genome-Wide Mapping of in Vivo Protein-DNA Interactions
2007 StandoutScience
Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing
2002 StandoutScience
A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice
2007 StandoutScienceNobel
Transcriptional Maps of 10 Human Chromosomes at 5-Nucleotide Resolution
2005 Science
Polycomb Repressive Complex 2 Is Dispensable for Maintenance of Embryonic Stem Cell Pluripotency
2008
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
2011 StandoutScience
A mammalian protein with specific demethylase activity for mCpG DNA
1999 Nature
Reversal of GSTP1 CpG island hypermethylation and reactivation of pi-class glutathione S-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamide.
2001
The profile of repeat‐associated histone lysine methylation states in the mouse epigenome
2005
Genome-wide gain-of-function screen identifies novel regulators of pluripotency
2010
Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing
2005
Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal
2012
Multiple Structural Maintenance of Chromosome Complexes at Transcriptional Regulatory Elements
2013
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1
2004 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Syndromes of disordered chromatin remodeling
2003
Esrrb Is a Direct Nanog Target Gene that Can Substitute for Nanog Function in Pluripotent Cells
2012
The DNA methylation paradox
1999
NuRD Suppresses Pluripotency Gene Expression to Promote Transcriptional Heterogeneity and Lineage Commitment
2012
Histone variants, nucleosome assembly and epigenetic inheritance
2004
Genomic views of distant-acting enhancers
2009 Nature
Genome-Wide Analyses Reveal RNA Polymerase II Located Upstream of Genes Poised for Rapid Response upon S. cerevisiae Stationary Phase Exit
2005
Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development
2001
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma
2002
Novel RNAs Identified From an In-Depth Analysis of the Transcriptome of Human Chromosomes 21 and 22
2004
Methylation-Induced Repression— Belts, Braces, and Chromatin
1999
Association of the Histone Methyltransferase Set2 with RNA Polymerase II Plays a Role in Transcription Elongation
2002
SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells
2004
Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation
1999
Transcriptional Regulation and Its Misregulation in Disease
2013
Molecular genetics of Rett syndrome and clinical spectrum of MECP2 mutations
2001
SUZ12 Is Required for Both the Histone Methyltransferase Activity and the Silencing Function of the EED-EZH2 Complex
2004
Genome-wide Map of Nucleosome Acetylation and Methylation in Yeast
2005
A new frontier for molecular medicine: Noncoding RNAs
2005
Distinction and Relationship between Elongation Rate and Processivity of RNA Polymerase II In Vivo
2005
The Genetic Signatures of Noncoding RNAs
2009
MYC on the Path to Cancer
2012 Standout
Histone H2B Monoubiquitination Functions Cooperatively with FACT to Regulate Elongation by RNA Polymerase II
2006
Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts
2011
Strategies and New Developments in the Generation of Patient-Specific Pluripotent Stem Cells
2007 StandoutNobel
CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression
2010
Chd1 regulates open chromatin and pluripotency of embryonic stem cells
2009 Nature
The history of cancer epigenetics
2004 Standout
Control of the Embryonic Stem Cell State
2011
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
2011 StandoutNatureNobel
The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote
2004
CpG-binding Protein (CXXC Finger Protein 1) Is a Component of the Mammalian Set1 Histone H3-Lys4 Methyltransferase Complex, the Analogue of the Yeast Set1/COMPASS Complex
2005
Epigenomic Annotation of Enhancers Predicts Transcriptional Regulators of Human Neural Crest
2012
Genomic imprinting in mammals: an interplay between chromatin and DNA methylation?
1999
A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers
2010
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
2009 Nature
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
The H19 methylation imprint is erased and re-established differentially on the parental alleles during male germ cell development
2000
Methylation-dependent silencing at the H19 imprinting control region by MeCP2
2002
Chromatin Connections to Pluripotency and Cellular Reprogramming
2011
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
2001
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
2000
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
2008
Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome
2005
Analysis of the Vertebrate Insulator Protein CTCF-Binding Sites in the Human Genome
2007
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
2007 StandoutNobel
Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene
2004 Nature
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains
2008
Methyl-CpG Binding Domain Protein 2 Represses Transcription from Hypermethylated π-Class Glutathione S-Transferase Gene Promoters in Hepatocellular Carcinoma Cells
2002
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
1999 Standout
Mapping of genetic and epigenetic regulatory networks using microarrays
2005
Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal
2009
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells
2008
Employment opportunities for non‐coding RNAs
2004
p53: new roles in metabolism
2007
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
Gilbert’s conjecture: the search for DNA (cytosine-5) demethylases and the emergence of new functions for eukaryotic DNA (cytosine-5) methyltransferases 1 1Edited by J. Karn
2000
In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants
2006 StandoutNobel
Methyl-CpG-binding protein 2 mutations in Rett syndrome
2000
Global Position and Recruitment of HATs and HDACs in the Yeast Genome
2004
Chromatin plasticity and genome organization in pluripotent embryonic stem cells
2010
Control of NF- B-dependent Transcriptional Responses by Chromatin Organization
2009
An upstream repressor element plays a role in Igf2 imprinting
2001
Global nucleosome occupancy in yeast
2004
de FACTo Nucleosome Dynamics
2006
Eukaryotic DNA methylation as an evolutionary device
1999
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
2006 Standout
Reprogramming Cellular Identity for Regenerative Medicine
2012
BUR Kinase Selectively Regulates H3 K4 Trimethylation and H2B Ubiquitylation through Recruitment of the PAF Elongation Complex
2005
Defining the CREB Regulon
2004
DNA methylation in health and disease
2000
Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B
2004
The human Mi-2/NuRD complex and gene regulation
2007
The many faces of REST oversee epigenetic programming of neuronal genes
2005
Pax6 Is a Human Neuroectoderm Cell Fate Determinant
2010
Menin Associates with a Trithorax Family Histone Methyltransferase Complex and with the Hoxc8 Locus
2004
Spatial Distribution of Di- and Tri-methyl Lysine 36 of Histone H3 at Active Genes
2005
The Epigenomics of Cancer
2007 Standout
Histone H3 Lysine 4 Mono-methylation does not Require Ubiquitination of Histone H2B
2005
Genome-wide analysis of transcription factor binding sites based on ChIP-Seq data
2008
Mediator and cohesin connect gene expression and chromatin architecture
2010 Nature
DNA methylation represses transcription in vivo
1999
Forcing cells to change lineages
2009 Nature
Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse
2005
MeCP2 dysfunction in Rett syndrome and related disorders
2006
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state
2009
Rapid evolution of noncoding RNAs: lack of conservation does not mean lack of function
2005
A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal
2009
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Genome-wide transcription and the implications for genomic organization
2007
Stable Histone Deacetylase Complexes Distinguished by the Presence of SANT Domain Proteins CoREST/kiaa0071 and Mta-L1
2001
Regulation of p53 tumour suppressor target gene expression by the p52 NF‐κB subunit
2006
Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs
2007
The key to development: interpreting the histone code?
2005
A unique chromatin signature uncovers early developmental enhancers in humans
2010 StandoutNature
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage
2002 StandoutNatureNobel
The NIH Roadmap Epigenomics Mapping Consortium
2010
Resolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst
2010
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Evidence for nucleosome depletion at active regulatory regions genome-wide
2004
MECP2 truncating mutations cause histone H4 hyperacetylation in Rett syndrome
2001
A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells
2007 Standout
Role of DNA Methylation in the Regulation of Cell Function: Autoimmunity, Aging and Cancer
2002
Genomic imprinting and seed development: endosperm formation with and without sex
2001
Chromatin signature of embryonic pluripotency is established during genome activation
2010 Nature
Myc-binding-site recognition in the human genome is determined by chromatin context
2006
Functional Anatomy of Polycomb and Trithorax Chromatin Landscapes in Drosophila Embryos
2009
Suv39h-Mediated Histone H3 Lysine 9 Methylation Directs DNA Methylation to Major Satellite Repeats at Pericentric Heterochromatin
2003
Selective and antagonistic functions of SWI/SNF and Mi-2β nucleosome remodeling complexes during an inflammatory response
2006
Histone H3 lysine 4 methylation patterns in higher eukaryotic genes
2003
Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming
2008
Lineage-Specific Polycomb Targets and De Novo DNA Methylation Define Restriction and Potential of Neuronal Progenitors
2008
The c-Myc target gene network
2006
Non-coding RNA
2006 Standout
Genome-wide analysis of coordinate expression and evolution of human encoded sense-antisense transcripts
2005
Active demethylation of the paternal genome in the mouse zygote
2000
The Methyl-CpG-binding Protein MeCP2 Links DNA Methylation to Histone Methylation
2003
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
2010 Standout
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
2000
p53 in health and disease
2007 Standout
Polycomb-like 2 Associates with PRC2 and Regulates Transcriptional Networks during Mouse Embryonic Stem Cell Self-Renewal and Differentiation
2010
Reprogramming towards pluripotency requires AID-dependent DNA demethylation
2009 Nature
Genome-wide map of regulatory interactions in the human genome
2014
Generation of germline-competent induced pluripotent stem cells
2007 StandoutNatureNobel
Cotranscriptional Set2 Methylation of Histone H3 Lysine 36 Recruits a Repressive Rpd3 Complex
2005
Modifying chromatin and concepts of cancer
1999
Cancer-epigenetics comes of age
1999 Standout
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Dynamic Lysine Methylation on Histone H3 Defines the Regulatory Phase of Gene Transcription
2005
Reactivating the expression of methylation silenced genes in human cancer
2002
Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: correlation of accessibility, methylation, MeCP2 binding and acetylation
2001
EMT: 2016
2016 Standout
The Paf1 Complex Is Essential for Histone Monoubiquitination by the Rad6-Bre1 Complex, Which Signals for Histone Methylation by COMPASS and Dot1p
2003
Origin of phenotypes: Genes and transcripts
2007
Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells
2005 Standout
The Role of Chromatin during Transcription
2007 Standout
A COMPASS in the voyage of defining the role of trithorax/MLL-containing complexes: Linking leukemogensis to covalent modifications of chromatin
2005
The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells
2003
Histone Variant H2A.Z Marks the 5′ Ends of Both Active and Inactive Genes in Euchromatin
2005
The interactomes of POU5F1 and SOX2 enhancers in human embryonic stem cells
2013
PRDM14 Ensures Naive Pluripotency through Dual Regulation of Signaling and Epigenetic Pathways in Mouse Embryonic Stem Cells
2013
Histone methylation versus histone acetylation: new insights into epigenetic regulation
2001
DNA methyltransferase Dnmt1 associates with histone deacetylase activity
2000
Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming
2010
DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
1999 Standout
Myc influences global chromatin structure
2006
Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains
2011
Genomic Binding and Transcriptional Regulation by the Drosophila Myc and Mnt Transcription Factors
2005
Chromatin immunoprecipitation and microarray-based analysis of protein location
2006
The NuRD component Mbd3 is required for pluripotency of embryonic stem cells
2006
Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells
2008
Revealing the world of RNA interference
2004 StandoutNatureNobel
Cellular Memory and the Histone Code
2002
Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal
2010
Gene expression patterns vary in clonal cell cultures from Rett syndrome females with eight different MECP2 mutations
2002
Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells
2015 Standout
Mechanisms for ATP-dependent chromatin remodelling: farewell to the tuna-can octamer?
2004
Elongation by RNA polymerase II: the short and long of it
2004
ATXR5 and ATXR6 are H3K27 monomethyltransferases required for chromatin structure and gene silencing
2009
Breaking barriers to transcription elongation
2006
Variant Histone H2A.Z Is Globally Localized to the Promoters of Inactive Yeast Genes and Regulates Nucleosome Positioning
2005
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
2001
Mice with Truncated MeCP2 Recapitulate Many Rett Syndrome Features and Display Hyperacetylation of Histone H3
2002
The Set2 Histone Methyltransferase Functions through the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II
2003
Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation
1999
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
2001
Waves of Retrotransposon Expansion Remodel Genome Organization and CTCF Binding in Multiple Mammalian Lineages
2012
Embryonic stem cell potency fluctuates with endogenous retrovirus activity
2012 Nature
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Evolution and Functions of Long Noncoding RNAs
2009 Standout
Stopped at the border: boundaries and insulators
1999
Histone H2B Ubiquitylation Controls Processive Methylation but Not Monomethylation by Dot1 and Set1
2005
The many faces of histone lysine methylation
2002
Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells
2013
Chromatin remodelling: the industrial revolution of DNA around histones
2006
Binary switches and modification cassettes in histone biology and beyond
2003 Nature
Beckwith-Wiedemann syndrome: imprinting in clusters revisited
2000
Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs
2008 Nature
Characterization of genome-wide p53-binding sites upon stress response
2008
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
Methylation of Histone H3 K4 Mediates Association of the Isw1p ATPase with Chromatin
2003
Cytosine methylation and mammalian development
1999
What is a gene, post-ENCODE? History and updated definition
2007
The fundamental role of epigenetic events in cancer
2002 Standout
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
2014 Standout
Long non-coding RNAs: insights into functions
2009 Standout
Histone acetylation and an epigenetic code
2000
Noncanonical DNA Motifs as Transactivation Targets by Wild Type and Mutant p53
2008
Purification and Functional Characterization of SET8, a Nucleosomal Histone H4-Lysine 20-Specific Methyltransferase
2002
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
The Paf1 Complex Is Required for Histone H3 Methylation by COMPASS and Dot1p: Linking Transcriptional Elongation to Histone Methylation
2003
Histone H3 Methylation by Set2 Directs Deacetylation of Coding Regions by Rpd3S to Suppress Spurious Intragenic Transcription
2005
Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8
2003
Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast
2003
Chromatin Signatures in Multipotent Human Hematopoietic Stem Cells Indicate the Fate of Bivalent Genes during Differentiation
2009
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
Suppression of induced pluripotent stem cell generation by the p53–p21 pathway
2009 StandoutNatureNobel
Chromatin structure and the inheritance of epigenetic information
2010
Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells
2009
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Molecular evidence indicating that the yeast PAF complex is required for transcription elongation
2004
Methylation of Histone H3 by Set2 in Saccharomyces cerevisiae Is Linked to Transcriptional Elongation by RNA Polymerase II
2003
Evidence for Eviction and Rapid Deposition of Histones upon Transcriptional Elongation by RNA Polymerase II
2004
Drosophila Paf1 Modulates Chromatin Structure at Actively Transcribed Genes
2005
ATP-Dependent Chromatin-Remodeling Complexes
2000
Modulation of DNA Binding Protein Affinity Directly Affects Target Site Demethylation
2000
Eaf3 Chromodomain Interaction with Methylated H3-K36 Links Histone Deacetylation to Pol II Elongation
2005
Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells
2007
Advances in skin grafting and treatment of cutaneous wounds
2014 StandoutScience
Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors
2008 StandoutScienceNobel
Eukaryotic transcriptional control
1999 StandoutNobel
Generation of Transgene-Free Lung Disease-Specific Human Induced Pluripotent Stem Cells Using a Single Excisable Lentiviral Stem Cell Cassette
2010
Quality Control by DNA Repair
1999 StandoutScienceNobel
Histone modification patterns associated with the human X chromosome
2006
Neutral evolution of ‘non-coding’ complementary DNAs (reply)
2004 Nature
Histone H2B Ubiquitylation Is Associated with Elongating RNA Polymerase II
2005
NONCODING RNAS IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM
2006
Histone Acetyltransferases
2001 Standout
Impaired generation of mature neurons by neural stem cells from hypomorphic Sox2 mutants
2008
Recruitment of Polycomb group complexes and their role in the dynamic regulation of cell fate choice
2009
Epigenetic Reprogramming in Mammalian Development
2001 StandoutScience
DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation
2003 Science
Control of Pancreas and Liver Gene Expression by HNF Transcription Factors
2004 Science
Methylation of histone H3 Lys 4 in coding regions of active genes
2002
Genome-Wide Analysis of Protein-DNA Interactions
2006
Lysine-Specific Demethylase 1 Regulates the Embryonic Transcriptome and CoREST Stability
2010
Dimethylation of Histone H3 at Lysine 36 Demarcates Regulatory and Nonregulatory Chromatin Genome-Wide
2005
Chromatin Modifications by Methylation and Ubiquitination: Implications in the Regulation of Gene Expression
2006
An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network
2009
Transcriptional control of human p53-regulated genes
2008 Standout
Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity
2008
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency
2009
Genome‐wide natural antisense transcription: coupling its regulation to its different regulatory mechanisms
2006
SWI/SNF Displaces SAGA-Acetylated Nucleosomes
2006
Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells
1999
Global mapping of c-Myc binding sites and target gene networks in human B cells
2006
Asf1 Mediates Histone Eviction and Deposition during Elongation by RNA Polymerase II
2006
The Role of DNA Methylation in Mammalian Epigenetics
2001 StandoutScience
Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine.
2002
The genomic landscape of histone modifications in human T cells
2006
A Strategy for Probing the Function of Noncoding RNAs Finds a Repressor of NFAT
2005 Science
The Spt4p Subunit of Yeast DSIF Stimulates Association of the Paf1 Complex with Elongating RNA Polymerase II
2006
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
1999 Standout
The Drosophila Polycomb Group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3
2001
Transcriptional Regulatory Elements in the Human Genome
2006
Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain
2002
Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome
2004
Promoter targeting of chromatin-modifying complexes
2001
Stability of the hybrid epithelial/mesenchymal phenotype
2016
Human DNA Repair Genes
2001 StandoutScienceNobel
Transcription factor heterogeneity in pluripotent stem cells: a stochastic advantage
2014
CoREST is an integral component of the CoREST- human histone deacetylase complex
2001
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Domain-Wide Displacement of Histones by Activated Heat Shock Factor Occurs Independently of Swi/Snf and Is Not Correlated with RNA Polymerase II Density
2005
Identification and Characterization of a Family of Mammalian Methyl-CpG Binding Proteins
1998
DNA Methylation and Histone Deacetylation in the Control of Gene Expression: Basic Biochemistry to Human Development and Disease
2001
Global and Hox-specific roles for the MLL1 methyltransferase
2005
Chromatin Immunoprecipitation-Based Screen To Identify Functional Genomic Binding Sites for Sequence-Specific Transactivators
2005
Mechanisms of Polycomb gene silencing: knowns and unknowns
2009
The Myc Transactivation Domain Promotes Global Phosphorylation of the RNA Polymerase II Carboxy-Terminal Domain Independently of Direct DNA Binding
2007
Eukaryotic transcriptional control
1999 StandoutNobel
NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression
2011
Works of Huck‐Hui Ng being referenced
The Rtf1 Component of the Paf1 Transcriptional Elongation Complex Is Required for Ubiquitination of Histone H2B
2003
Transcriptional Regulation of Nanog by OCT4 and SOX2
2005
p53-regulated Transcriptional Program Associated with Genotoxic Stress-induced Apoptosis
2004
Sall4 Interacts with Nanog and Co-occupies Nanog Genomic Sites in Embryonic Stem Cells
2006
Rewirable gene regulatory networks in the preimplantation embryonic development of three mammalian species
2010
Sall4 Regulates Distinct Transcription Circuitries in Different Blastocyst-Derived Stem Cell Lineages
2008
Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity
2003
Reduced Oct4 Expression Directs a Robust Pluripotent State with Distinct Signaling Activity and Increased Enhancer Occupancy by Oct4 and Nanog
2013
Tackling the epigenome: challenges and opportunities for collaboration
2010
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity
2010 Nature
Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association
2002
Ubiquitination of Histone H2B by Rad6 Is Required for Efficient Dot1-mediated Methylation of Histone H3 Lysine 79
2002
Molecular framework underlying pluripotency
2008
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
1999 Nature
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
2007
Genome-wide Mapping of RELA(p65) Binding Identifies E2F1 as a Transcriptional Activator Recruited by NF-κB upon TLR4 Activation
2007
Molecules that Promote or Enhance Reprogramming of Somatic Cells to Induced Pluripotent Stem Cells
2009
Transcriptional and epigenetic regulations of embryonic stem cells
2008
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
1999
A core Klf circuitry regulates self-renewal of embryonic stem cells
2008
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
1999
Induction of a Human Pluripotent State with Distinct Regulatory Circuitry that Resembles Preimplantation Epiblast
2013
Unbiased Mapping of Transcription Factor Binding Sites along Human Chromosomes 21 and 22 Points to Widespread Regulation of Noncoding RNAs
2004
The transcriptional and signalling networks of pluripotency
2011
Evolution of the mammalian transcription factor binding repertoire via transposable elements
2008
Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb
2009
Genome-wide location and regulated recruitment of the RSC nucleosome-remodeling complex
2002
Histone deacetylases: silencers for hire
2000
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients
2010 Nature
Transposable elements have rewired the core regulatory network of human embryonic stem cells
2010
Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1
2006
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
1998 StandoutNature
The transcriptional regulation of pluripotency
2012
DNA methylation and chromatin modification
1999
Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming
2012
Tbx3 improves the germ-line competency of induced pluripotent stem cells
2010 Nature
Methylation of H3-Lysine 79 Is Mediated by a New Family of HMTases without a SET Domain
2002
Whole-Genome Mapping of Histone H3 Lys4 and 27 Trimethylations Reveals Distinct Genomic Compartments in Human Embryonic Stem Cells
2007
The Nuclear Receptor Nr5a2 Can Replace Oct4 in the Reprogramming of Murine Somatic Cells to Pluripotent Cells
2010
Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells
2009
Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: A potential mechanism for position-effect variegation
2003
Active Repression of Methylated Genes by the Chromosomal Protein MBD1
2000
T-Cell Factor 3 Regulates Embryonic Stem Cell Pluripotency and Self-Renewal by the Transcriptional Control of Multiple Lineage Pathways
2008
A PRC2-Dependent Repressive Role of PRDM14 in Human Embryonic Stem Cells and Induced Pluripotent Stem Cell Reprogramming
2012
Reciprocal Transcriptional Regulation of Pou5f1 and Sox2 via the Oct4/Sox2 Complex in Embryonic Stem Cells
2005
KLF4 and PBX1 Directly Regulate NANOG Expression in Human Embryonic Stem Cells
2009
Zfp143 Regulates Nanog Through Modulation of Oct4 Binding
2008
p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling
2005
BLIMP1 regulates cell growth through repression of p53 transcription
2007
Mapping the networks for pluripotency
2011
Zic3 Is Required for Maintenance of Pluripotency in Embryonic Stem Cells
2007