Standout Papers
Citation Impact
Citing Papers
A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery
2019
Restriction of PD-1 function by cis -PD-L1/CD80 interactions is required for optimal T cell responses
2019 Science
Targeted cell killing by reconstituted caspases
2007 StandoutNobel
Sulfur [ 18 F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis
2021 StandoutNobel
PD-L1 Binds to B7-1 Only In Cis on the Same Cell Surface
2018
The CCR5 and CXCR4 Coreceptors—Central to Understanding the Transmission and Pathogenesis of Human Immunodeficiency Virus Type 1 Infection
2004
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
2017 StandoutNature
X4 and R5 HIV-1 Have Distinct Post-entry Requirements for Uracil DNA Glycosylase during Infection of Primary Cells
2010 StandoutNobel
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Design, synthesis and biological evaluation of β-carboline derivatives as novel inhibitors targeting B-Raf kinase
2012
Function of Rho family proteins in actin dynamics during phagocytosis and engulfment
2000
Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy
2005 Standout
The phagocytosis of apoptotic cells
2001
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
The Erv family of sulfhydryl oxidases
2007
The dynamic disulphide relay of quiescin sulphydryl oxidase
2012 StandoutNatureNobel
Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte
2005
Conditional Forebrain Inactivation of Nicastrin Causes Progressive Memory Impairment and Age-Related Neurodegeneration
2009 StandoutNobel
Regulated portals of entry into the cell
2003 StandoutNature
Cell Death
2004 Standout
Genetic models for the clearance of apoptotic cells
2004
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
2015 Standout
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity
2017 StandoutNobel
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1
2015
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Novel cancer immunotherapy agents with survival benefit: recent successes and next steps
2011 StandoutNobel
Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor
2002
Apoptotic cell removal
2001
Structural Insights into the Mechanisms of Antibody-Mediated Neutralization of Flavivirus Infection: Implications for Vaccine Development
2008
Systemic Lupus Erythematosus
2011 Standout
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Molecular mechanisms of T cell co-stimulation and co-inhibition
2013 Standout
Loss of nicastrin elicits an apoptotic phenotype in mouse embryos
2006
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
EMT: 2016
2016 Standout
Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals
2020 Standout
A Blueprint for HIV Vaccine Discovery
2012
Negative regulators of T‐cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections
2009 StandoutNobel
Developing Covalent Protein Drugs via Proximity-Enabled Reactive Therapeutics
2020
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Survey of the year 2003 commercial optical biosensor literature
2004
In Vivo Identification of Novel Regulators and Conserved Pathways of Phagocytosis in A. gambiae
2005
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application
2013 StandoutNobel
Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex
2020
SARS-CoV-2 vaccines in development
2020 StandoutNature
Clearance of Apoptotic Cells
2004
Lysine Methylation as a Routine Rescue Strategy for Protein Crystallization
2006
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2
2008
Immune Checkpoint PD‐1/PD‐L1: Is There Life Beyond Antibodies?
2017
VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses
2011
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
C–H Functionalization of Cyclopropanes: A Practical Approach Employing a Picolinamide Auxiliary
2013
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Molecular Determinants of T Cell Epitope Recognition to the Common Timothy Grass Allergen
2010
THE ENGULFMENT PROCESS OF PROGRAMMED CELL DEATH INCAENORHABDITIS ELEGANS
2004 Nobel
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody
2020 StandoutNobel
Tissue-specific expression of B7x protects from CD4 T cell–mediated autoimmunity
2011 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
The Programmed Death-1 Ligand 1:B7-1 Pathway Restrains Diabetogenic Effector T Cells In Vivo
2011
Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes
2014 StandoutNobel
Correlates of Protection Induced by Vaccination
2010 Standout
Works of Hua-Poo Su being referenced
Identification and Characterization of a Dimerization Domain in CED-6, an Adapter Protein Involved in Engulfment of Apoptotic Cells
2000
Interaction of CED-6/GULP, an Adapter Protein Involved in Engulfment of Apoptotic Cells with CED-1 and CD91/Low Density Lipoprotein Receptor-related Protein (LRP)
2002
Selective CD4+ T Cell Help for Antibody Responses to a Large Viral Pathogen: Deterministic Linkage of Specificities
2008
The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms
2005
Discovery of 1-Amino-5H-pyrido[4,3-b]indol-4-carboxamide Inhibitors of Janus Kinase 2 (JAK2) for the Treatment of Myeloproliferative Disorders
2011
Redundancy and Plasticity of Neutralizing Antibody Responses Are Cornerstone Attributes of the Human Immune Response to the Smallpox Vaccine
2008
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
2008 StandoutNobel
The 1.51-Å structure of the poxvirus L1 protein, a target of potent neutralizing antibodies
2005
Human Immunodeficiency Virus Type 1 Pathogenesis in SCID-hu Mice Correlates with Syncytium-Inducing Phenotype and Viral Replication
2000
The Structure of G4, the Poxvirus Disulfide Oxidoreductase Essential for Virus Maturation and Infectivity
2006