Standout Papers
Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Differential dynamics of the mammalian mRNA and protein expression response to misfolding stress
2016
Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations
2014 StandoutNobel
Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
2010 StandoutScience
Atomic-Level Characterization of the Structural Dynamics of Proteins
2010 StandoutScienceNobel
Protein structure determination using metagenome sequence data
2017 StandoutScienceNobel
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2
2020 Science
Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2)
2020 StandoutScience
Next-generation analysis of gene expression regulation – comparing the roles of synthesis and degradation
2015
A dynamic model of proteome changes reveals new roles for transcript alteration in yeast
2011
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Characterization of Functional Reprogramming during Osteoclast Development Using Quantitative Proteomics and mRNA Profiling
2014
Protein synthesis rate is the predominant regulator of protein expression during differentiation
2013
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Regulation of transcriptome, translation, and proteome in response to environmental stress in fission yeast
2012
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
NMDA Receptor-Nitric Oxide Transmission Mediates Neuronal Iron Homeostasis via the GTPase Dexras1
2006
Role of cholesterol in the function and organization of G-protein coupled receptors
2006
Oncogenic kinase signalling
2001 StandoutNature
Spectator no more, the role of the membrane in regulating ion channel function
2016
GFINDer: genetic disease and phenotype location statistical analysis and mining of dynamically annotated gene lists
2005
WNT signalling pathways as therapeutic targets in cancer
2012 Standout
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
2010 Standout
Microglia and neuroprotection: From in vitro studies to therapeutic applications
2010
Stem Cell Factor/c-kit Up-regulates Cyclin D3 and Promotes Cell Cycle Progression via the Phosphoinositide 3-Kinase/p70 S6 Kinase Pathway in Spermatogonia
2000
Neuronal Microtubule-associated Protein 2D Is a Dual A-kinase Anchoring Protein Expressed in Rat Ovarian Granulosa Cells
2004
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
2008 Standout
Cellular cholesterol trafficking and compartmentalization
2008
TIGAR Is Required for Efficient Intestinal Regeneration and Tumorigenesis
2013
Protein Expression Regulation under Oxidative Stress
2011
Membrane cholesterol stabilizes the human serotonin1A receptor
2012
Decoding ALS: from genes to mechanism
2016 StandoutNature
Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach
2020
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
2010 StandoutNatureNobel
Cloning of novel human SEC14p-like proteins: ligand binding and functional properties
2003
MMTV-Wnt1 and -ΔN89β-Catenin Induce Canonical Signaling in Distinct Progenitors and Differentially Activate Hedgehog Signaling within Mammary Tumors
2009
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Single-molecule fluorescence detection in microfluidic channels—the Holy Grail in μTAS?
2005
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection
2015
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
Metabolic Regulation by p53 Family Members
2013
U1 snRNP regulates cancer cell migration and invasion in vitro
2020 Standout
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
Astrocytes conspire with neurons during progression of neurological disease
2012
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
2011 StandoutNatureNobel
A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor
2008
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
Modulation of intracellular ROS levels by TIGAR controls autophagy
2009
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma
2010
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
2020 StandoutNature
Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER
2014
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Insights into the regulation of protein abundance from proteomic and transcriptomic analyses
2012 Standout
The role of senescent cells in ageing
2014 StandoutNature
Metal-Organic Framework Nanoparticle-Based Biomineralization: A New Strategy toward Cancer Treatment
2019
Structural basis for amino acid export by DMT superfamily transporter YddG
2016 Nature
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Virtual screening, ADME/Tox predictions and the drug repurposing concept for future use of old drugs against the COVID-19
2020
Microfluidic diagnostic technologies for global public health
2006 StandoutNature
Calculation of Proteins’ Total Side-Chain Torsional Entropy and Its Influence on Protein–Ligand Interactions
2009
Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes
2005 StandoutNatureNobel
The origins and the future of microfluidics
2006 StandoutNature
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Cytoprotective metal-organic frameworks for anaerobic bacteria
2018 StandoutNobel
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.
1988 StandoutNobel
Bacterial Mechanosensors
2017
Copper-Catalyzed Synthesis of Mixed Alkyl Aryl Phosphonates
2014 StandoutNobel
Tandem Facial Amphiphiles for Membrane Protein Stabilization
2010 StandoutNobel
Activation of a potassium current by rapid photochemically generated step increases of intracellular calcium in rat sympathetic neurons.
1987 StandoutNobel
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death
2012
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Recent Progress on Ferroelectric Polymer-Based Nanocomposites for High Energy Density Capacitors: Synthesis, Dielectric Properties, and Future Aspects
2016 Standout
Nanosecond to Microsecond Protein Dynamics Probed by Magnetic Relaxation Dispersion of Buried Water Molecules
2008
The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.
1990 StandoutNobel
Medicinal Chemistry of Nucleoside Phosphonate Prodrugs for Antiviral Therapy
2011
Rat brain serotonin receptors in Xenopus oocytes are coupled by intracellular calcium to endogenous channels.
1987 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
PECA: A Novel Statistical Tool for Deconvoluting Time-Dependent Gene Expression Regulation
2013
Works of Hua Li being referenced
Structural Insight into the Ion-Exchange Mechanism of the Sodium/Calcium Exchanger
2012 Science
Wnt5a Suppresses Epithelial Ovarian Cancer by Promoting Cellular Senescence
2011
microRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells
2009
Development and Preliminary Clinical Activity of PD-1-Guided CTLA-4 Blocking Bispecific DART Molecule
2020
Structural and Biochemical Studies of TIGAR (TP53-induced Glycolysis and Apoptosis Regulator)
2008
Diabetes Gene Therapy: Potential and Challenges
2003
Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence
2013
Glutamate induces neurotrophic factor production from microglia via protein kinase C pathway
2010
Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
2020 Standout
Peripheral-Type Benzodiazepine Receptor Function in Cholesterol Transport. Identification of a Putative Cholesterol Recognition/Interaction Amino Acid Sequence and Consensus Pattern1
1998
Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening
2009
Checkpoint-modulating immunotherapies in tumor treatment: Targets, drugs, and mechanisms
2018
Synthesis and Anti-HIV Evaluation of New Acyclic Phosphonate Nucleotide Analogues and Their Bis(SATE) Derivatives
2010
Blockade of Gap Junction Hemichannel Suppresses Disease Progression in Mouse Models of Amyotrophic Lateral Sclerosis and Alzheimer's Disease
2011
Dihydrostreptomycin Directly Binds to, Modulates, and Passes through the MscL Channel Pore
2016
Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition
2013
Infrequent cavity‐forming fluctuations in HPr from Staphylococcus carnosus revealed by pressure‐ and temperature‐dependent tyrosine ring flips
2004
Delayed Correlation of mRNA and Protein Expression in Rapamycin-treated Cells and a Role for Ggc1 in Cellular Sensitivity to Rapamycin
2009
Intracellular Delivery of Molecular Cargo Using Cell-Penetrating Peptides and the Combination Strategies
2015
Single-molecule spectroscopy for molecular identification in capillary electrophoresis
2004
Reciprocal Intraepithelial Interactions Between TP63 and Hedgehog Signaling Regulate Quiescence and Activation of Progenitor Elaboration by Mammary Stem Cells
2008
Regulation of Rat Testis Gonocyte Proliferation by Platelet-Derived Growth Factor and Estradiol: Identification of Signaling Mechanisms Involved*
1997
A 16 MJ compact pulsed power system for electromagnetic launch
2015
Identification, Localization, and Function in Steroidogenesis of PAP7: A Peripheral-Type Benzodiazepine Receptor- and PKA (RIα)-Associated Protein
2001