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Citing Papers
Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species
2010 StandoutScience
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
The role of cyclic nucleotides in central synaptic function
1975
Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion
2001
Molecular cloning and characterization of the rat NMDA receptor
1991 StandoutNature
Cloning and Characterization of a Novel Matrix Metalloproteinase (MMP), CMMP, from Chicken Embryo Fibroblasts
1998
Inflammation and cancer
2002 StandoutNature
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
Matrix-dependent Proteolysis of Surface Transglutaminase by Membrane-type Metalloproteinase Regulates Cancer Cell Adhesion and Locomotion
2001
Catalytic activities of membrane‐type 6 matrix metalloproteinase (MMP25)
2001
Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase
1991 StandoutNature
Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment
2000
Identification and Characterization of the Fifth Membrane-type Matrix Metalloproteinase MT5-MMP
1999
Gelatin Zymography and Substrate Cleavage Assays of Matrix Metalloproteinase-2 in Breast Carcinoma Cells Overexpressing Membrane Type-1 Matrix Metalloproteinase
2002
The Role of the C-terminal Domain of Human Collagenase-3 (MMP-13) in the Activation of Procollagenase-3, Substrate Specificity, and Tissue Inhibitor of Metalloproteinase Interaction
1997
Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis
2000 StandoutNature
Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome
2001
A dominant negative mutant of jun blocking 12-O-tetradecanoylphorbol-13-acetate–induced invasion in mouse keratinocytes
1997
Catalytic Activities and Substrate Specificity of the Human Membrane Type 4 Matrix Metalloproteinase Catalytic Domain
1999
Cloning and expression of a cDNA encoding an endothelin receptor
1990 StandoutNature
Tissue inhibitors of metalloproteinases: evolution, structure and function
2000 Standout
Inositol phosphates and cell signalling
1989 StandoutNature
Degradation of Interleukin 1β by Matrix Metalloproteinases
1996
Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis.
1998
Imaging in the era of molecular oncology
2008 StandoutNature
Development of Matrix Metalloproteinase Inhibitors in Cancer Therapy
2001
An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs
1987 Standout
Leukolysin/MMP25/MT6-MMP: a novel matrix metalloproteinase specifically expressed in the leukocyte lineage
1999
Three-dimensional Type I Collagen Lattices Induce Coordinate Expression of Matrix Metalloproteinases MT1-MMP and MMP-2 in Microvascular Endothelial Cells
1998
Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis
2008
Strategies for MMP inhibition in cancer: innovations for the post-trial era
2002
The Hallmarks of Cancer
2000 Standout
Transmembrane-deletion Mutants of the Membrane-type Matrix Metalloproteinase-1 Process Progelatinase A and Express Intrinsic Matrix-degrading Activity
1996
Kinetic Analysis of the Binding of Human Matrix Metalloproteinase-2 and -9 to Tissue Inhibitor of Metalloproteinase (TIMP)-1 and TIMP-2
1997
Characterization of a truncated recombinant form of human membrane type 3 matrix metalloproteinase
1999
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
1990 StandoutNature
Cloning of three Caenorhabditis elegans genes potentially encoding novel matrix metalloproteinases
1998
Old materials with new tricks: multifunctional open-framework materials
2007
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm
1993 StandoutNobel
Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention
1999
TIMP-2 Is Required for Efficient Activation of proMMP-2 in Vivo
2000
Identification and Characterization of a Novel Human Matrix Metalloproteinase with Unique Structural Characteristics, Chromosomal Location, and Tissue Distribution
1997
Tissue factor pathway inhibitor-2 is a novel inhibitor of matrix metalloproteinases with implications for atherosclerosis
2001
Cellular Activation of MMP-2 (Gelatinase A) by MT2-MMP Occurs via a TIMP-2-independent Pathway
2001
Immunity, Inflammation, and Cancer
2010 Standout
Growth factors, proteases and protease inhibitors in the maternal—fetaldialogue
1996
MT1-MMP-Deficient Mice Develop Dwarfism, Osteopenia, Arthritis, and Connective Tissue Disease due to Inadequate Collagen Turnover
1999
Matrix Metalloproteinases Regulate Neovascularization by Acting as Pericellular Fibrinolysins
1998
A Novel TIMP-3 Mutation Reveals a Common Molecular Phenotype in Sorsby's Fundus Dystrophy
2000
Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor
1998
Authentic Matrix Vesicles Contain Active Metalloproteases (MMP)
2001
Expression, purification and charaterization of recombinant mouse MT5‐MMP protein products
1999
Characterization of inositol 1,4,5-trisphosphate-sensitive (IsCaP) and-insensitive (IisCaP) nonmitochondrial Ca2+ pools in rat pancreatic acinar cells
1989
Structural properties of matrix metalloproteinases
1999
Biochemical Characterization of the Catalytic Domain of Human Matrix Metalloproteinase 19
2000
A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes
1990 StandoutNature
High Resolution Structure of the N-terminal Domain of Tissue Inhibitor of Metalloproteinases-2 and Characterization of Its Interaction Site with Matrix Metalloproteinase-3
1998
Matrix Metalloproteinases Collagenase-2, Macrophage Elastase, Collagenase-3, and Membrane Type 1-Matrix Metalloproteinase Impair Clotting by Degradation of Fibrinogen and Factor XII
2000
Matrix metal loproteinases and the development of cancer
1996
Inflammation in atherosclerosis
2002 StandoutNature
CA‐MMP: a matrix metalloproteinase with a novel cysteine array, but without the classic cysteine switch
1999
Timp-1 Is Important for Epithelial Proliferation and Branching Morphogenesis during Mouse Mammary Development
1999
Membrane type-1 matrix metalloproteinase and TIMP-2 in tumor angiogenesis
2003
The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor
1988 StandoutNatureNobel
Translational activation of the lck proto-oncogene
1988 StandoutNatureNobel
Proteolytic networks in cancer
2011
TIMP-2 Promotes Activation of Progelatinase A by Membrane-type 1 Matrix Metalloproteinase Immobilized on Agarose Beads
1998
Specific collagenolysis by gelatinase A, MMP‐2, is determined by the hemopexin domain and not the fibronectin‐like domain
2001
Matrix metalloproteinases in tumor–host cell communication
2002
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Complementation Cloning of , a Gene Encoding a Putative Metalloprotease Required for Intramembrane Cleavage of SREBPs
1997 Nobel
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Differential Roles of TIMP-4 and TIMP-2 in Pro-MMP-2 Activation by MT1-MMP
2001
Cysteine Array Matrix Metalloproteinase (CA-MMP)/MMP-23 Is a Type II Transmembrane Matrix Metalloproteinase Regulated by a Single Cleavage for Both Secretion and Activation
2000
Matrix metalloproteinases A review of their structure and role in acute coronary syndrome
2003
Cellular activation of proMMP‐13 by MT1‐MMP depends on the C‐terminal domain of MMP‐13
2002
Membrane Type 4 Matrix Metalloproteinase (MMP17) Has Tumor Necrosis Factor-α Convertase Activity but Does Not Activate Pro-MMP2
2000
Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 Å resolution
1998
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in the mouse uterus during the peri-implantation period
1997
Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity
1999 StandoutNature
Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
Local overexpression of TIMP-1 prevents aortic aneurysm degeneration and rupture in a rat model.
1998
Cloning and Characterization of Human MMP-23, a New Matrix Metalloproteinase Predominantly Expressed in Reproductive Tissues and Lacking Conserved Domains in Other Family Members
1999
Matrix Metalloproteinases
1999 Standout
Expression of Sorsby's Fundus Dystrophy Mutations in Human Retinal Pigment Epithelial Cells Reduces Matrix Metalloproteinase Inhibition and May Promote Angiogenesis
2002
Molecular Determinants of Metalloproteinase Substrate Specificity: Matrix Metalloproteinase Substrate Binding Domains, Modules, and Exosites
2002
Inflammatory Cytokines and Oxidized Low Density Lipoproteins Increase Endothelial Cell Expression of Membrane Type 1-Matrix Metalloproteinase
1999
A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
1999 StandoutNature
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
Matrix Metalloproteinases: Biologic Activity and Clinical Implications
2000
The human AQP4 gene: definition of the locus encoding two water channel polypeptides in brain.
1996 StandoutNobel
Exceptional Thermal Stability in a Supramolecular Organic Framework: Porosity and Gas Storage
2010 StandoutNobel
Cloning and expression of a widely distributed (type IV) adenylyl cyclase.
1991 StandoutNobel
Analysis of tissue inhibitor of metalloproteinases-2 effect on pro-matrix metalloproteinase-2 activation by membrane-type 1 matrix metalloproteinase using baculovirus/insect-cell expression system
2000
Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors.
1999
Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1
2012
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
Structural insight into the complex formation of latent matrix metalloproteinase 2 with tissue inhibitor of metalloproteinase 2
2002
Adenylyl Cyclase Amino Acid Sequence: Possible Channel- or Transporter-Like Structure
1989 StandoutScienceNobel
Human matrix metalloproteinase specificity studies using collagen sequence-based synthetic peptides
1996
Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family.
1991 StandoutNobel
Making the cut: Protease-mediated regulation of angiogenesis
2006
An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins
1987 StandoutNatureNobel
Pressure Response of Three-Dimensional Cyanide-Bridged Bimetallic Magnets
2008 StandoutNobel
Human DNA ligase I cDNA: cloning and functional expression in Saccharomyces cerevisiae.
1990 StandoutNobel
Molecular Biology of Learning: Modulation of Transmitter Release
1982 StandoutScienceNobel
Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance.
1994 StandoutNobel
Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors.
2000
Degradation of decorin by matrix metalloproteinases: identification of the cleavage sites, kinetic analyses and transforming growth factor-β1 release
1997
A novel hydra matrix metalloproteinase (HMMP) functions in extracellular matrix degradation, morphogenesis and the maintenance of differentiated cells in the foot process
2000
Matrix metalloproteinases: structures, evolution, and diversification
1998
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Both subunits of rat liver ferritin are regulated at a translational level by iron induction
1986
Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen
1989 StandoutScience
Matrix remodeling in experimental and human heart failure: a possible regulatory role for TIMP-3
2003
Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1
1997 NatureNobel
Free calcium in heart muscle at rest and during contraction measured with Ca2+-sensitive microelectrodes
1980 StandoutNatureNobel
Multistage nanoparticle delivery system for deep penetration into tumor tissue
2011 StandoutNobel
Membrane-Type 1 Matrix Metalloproteinase Cleaves Cd44 and Promotes Cell Migration
2001
Characterization of the terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5' untranslated region and poly(A) tails at the 3' end.
1991 StandoutNobel
Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis
2016 StandoutNobel
Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations
2002 StandoutScience
Cyclic AMP-dependent protein kinase closes the serotonin-sensitive K+channels of Aplysia sensory neurones in cell-free membrane patches
1985 StandoutNatureNobel
Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2.
1998
MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment
1999
Precise Control and Consecutive Modulation of Spin Transition Temperature Using Chemical Migration in Porous Coordination Polymers
2011 StandoutNobel
Neurotransmitter and cyclic nucleotide modulation of frog cardiac contractility
1978
Matrilysin-2, a new matrix metalloproteinase expressed in human tumors and showing the minimal domain organization required for secretion, latency, and activity.
2000
Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases
2003 Standout
Dynamics of matrix turnover during pathologic remodeling of the extracellular matrix.
1996
Metalloproteinase inhibitors: biological actions and therapeutic opportunities
2002
Injection of catalytic subunit of cAMP-dependent protein kinase into isolated cardiac myocytes
1983
Design and Therapeutic Application of Matrix Metalloproteinase Inhibitors
1999
A Novel Tissue Inhibitor of Metalloproteinases-3 Mutation Reveals a Common Molecular Phenotype in Sorsby's Fundus Dystrophy
2000
Immunological dissimilarity of the calcium pump protein of skeletal and cardiac muscle sarcoplasmic reticulum
1980
Cloning of the cDNA for the human beta 1-adrenergic receptor.
1987 StandoutNobel
Characterization of inositol 1,4,5-trisphosphate-stimulated calcium release from rat cerebellar microsomal fractions. Comparison with [3H]inositol 1,4,5-trisphosphate binding.
1988
Co-translational membrane integration of calcium pump protein without signal sequence cleavage
1981 StandoutNatureNobel
Works of Horst Will being referenced
The Soluble Catalytic Domain of Membrane Type 1 Matrix Metalloproteinase Cleaves the Propeptide of Progelatinase A and Initiates Autoproteolytic Activation
1996
Biochemical Characterization of the Catalytic Domain of Membrane-Type 4 Matrix Metalloproteinase
1999
Membrane‐Type Matrix Metalloproteinases 1 and 2 Exhibit Broad‐Spectrum Proteolytic Capacities Comparable to Many Matrix Metalloproteinases
1997
Membrane‐Type‐2 Matrix Metalloproteinase Can Initiate the Processing of Progelatinase A and is Regulated by the Tissue Inhibitors of Metalloproteinases
1997
Cellular Mechanisms for Human Procollagenase-3 (MMP-13) Activation
1996
The TIMP2 Membrane Type 1 Metalloproteinase “Receptor” Regulates the Concentration and Efficient Activation of Progelatinase A
1998
cDNA Sequence and mRNA Tissue Distribution of a Novel Human Matrix Metalloproteinase with a Potential Transmembrane Segment
1995
Activation of Progelatinase A and Progelatinase A/TIMP-2 Complex by Membrane Type 2-Matrix Metalloproteinase
1997
cDNA Sequence and mRNA Tissue Distribution of a Novel Human Matrix Metalloproteinase with a Potential Transmembrane Segment
1995
Anion dependence of Ca2+ transport and (Ca2+ + K+)-stimulated Mg2+-dependent transport ATPase in rat pancreatic endoplasmic reticulum.
1987
61 Helices from Tetrahedral Ribbons [BP2O]: Isostructural Borophosphates MIMII(H2O)2[BP2O8] · H2O (MI = Na, K; MII = Mg, Mn, Fe, Co, Ni, Zn) and Their Dehydration to Microporous Phases MIMII(H2O)[BP2O8]
1997
Binding of calcium to a cell membrane-enriched preparation from pig myocardium: increase in calcium affinity upon membrane protein phosphorylation enhanced by a membrane-bound cyclic AMP-dependent protein kinase.
1973
Structure of human ferritin light subunit messenger RNA: comparison with heavy subunit message and functional implications.
1985
Partial characterization of protein kinase-catalyzed phosphorylation of low molecular weight proteins in purified preparations of pigeon heart sarcolemma and sarcoplasmic reticulum☆
1978