Citation Impact
Citing Papers
The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans
2019 Science
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
Navigating cognition: Spatial codes for human thinking
2018 ScienceNobel
Tau: Enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies
2021 Science
Role of α-Synuclein in Inducing Innate and Adaptive Immunity in Parkinson Disease
2015
Treg-based immunotherapy for antigen-specific immune suppression and stable tolerance induction: a perspective
2023 StandoutNobel
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging
2023 Standout
Roles of tau protein in health and disease
2017
Apolipoprotein E4, inhibitory network dysfunction, and Alzheimer’s disease
2019
Microglia receptors and their implications in the response to amyloid β for Alzheimer’s disease pathogenesis
2014
Challenges for Alzheimer's Disease Therapy: Insights from Novel Mechanisms Beyond Memory Defects
2018
Alzheimer disease
2021
Exosome reduction in vivo is associated with lower amyloid plaque load in the 5XFAD mouse model of Alzheimer's disease
2014
Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis
2015 Standout
Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate
2016
Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease
2014
Regulation and Functions of the ER-Associated Nrf1 Transcription Factor
2022 StandoutNobel
Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
2019 Standout
A guide to machine learning for biologists
2021
Graph Neural Networks and Their Current Applications in Bioinformatics
2021
Unsupervised deep learning identifies semantic disentanglement in single inferotemporal face patch neurons
2021 StandoutNobel
Therapeutic applications of compounds in the Magnolia family
2011 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Ageing as a risk factor for neurodegenerative disease
2019 Standout
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
Oxidative stress and the amyloid beta peptide in Alzheimer’s disease
2017 Standout
The Evolution of Preclinical Alzheimer’s Disease: Implications for Prevention Trials
2014
Somatic genomic changes in single Alzheimer’s disease neurons
2022 Nature
Nuclear Receptors License Phagocytosis by Trem2+Myeloid Cells in Mouse Models of Alzheimer's Disease
2015
A comparative review of cell culture systems for the study of microglial biology in Alzheimer’s disease
2012
Toxicity of lead: a review with recent updates
2012 Standout
Dementia in Down syndrome: unique insights for Alzheimer disease research
2019
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Shedding light on the cell biology of extracellular vesicles
2018 Standout
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
2016 Standout
The Role of Cardiovascular Risk Factors and Stroke in Familial Alzheimer Disease
2016
Multimodal biomedical AI
2022 Standout
The JAK/STAT signaling pathway: from bench to clinic
2021 Standout
Toward precision medicine in Alzheimer’s disease
2016
The Biology of T Regulatory Type 1 Cells and Their Therapeutic Application in Immune-Mediated Diseases
2018
Therapeutics of Alzheimer's disease: Past, present and future
2013
Alzheimer’s disease drug-development pipeline: few candidates, frequent failures
2014 Standout
Design, Synthesis, and Biological Evaluation of Coumarin Derivatives Tethered to an Edrophonium‐like Fragment as Highly Potent and Selective Dual Binding Site Acetylcholinesterase Inhibitors
2010
Aluminium and lead: molecular mechanisms of brain toxicity
2008
The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication
2020 Standout
Inhibitory effect of ethanol extract of Magnolia officinalis and 4-O-methylhonokiol on memory impairment and neuronal toxicity induced by beta-amyloid
2009
Alzheimer's disease
2016 Standout
Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease
2013
Drug pipeline in neurodegeneration based on transgenic mice models of Alzheimer's disease
2012
Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology
2017
Stem cell models of Alzheimer’s disease: progress and challenges
2017
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Revisiting the role of acetylcholinesterase in Alzheimer’s disease: cross-talk with P-tau and β-amyloid
2011
Procyanidins and Alzheimer’s Disease
2019
Metal Toxicity Links to Alzheimer's Disease and Neuroinflammation
2019
Acetylcholinesterase Inhibitors: Pharmacology and Toxicology
2013 Standout
Bivalent Ligands Derived from Huperzine A as Acetylcholinesterase Inhibitors
2007
Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony
2019 Standout
Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes
2014
Neuroprotective effects of the andrographolide analogue AL-1 in the MPP+/MPTP-induced Parkinson's disease model in vitro and in mice
2014
Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease
2016
Resveratrol Derivatives as Potential Treatments for Alzheimer’s and Parkinson’s Disease
2020
Bis(propyl)-cognitin protects against glutamate-induced neuro-excitotoxicity via concurrent regulation of NO, MAPK/ERK and PI3-K/Akt/GSK3β pathways
2013
Peripheral immune system in aging and Alzheimer’s disease
2018
Down syndrome
2020 Standout
The road to restoring neural circuits for the treatment of Alzheimer's disease
2016 Nature
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Tau Kinetics in Neurons and the Human Central Nervous System
2018
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
2020 Standout
Exosomes, an Unmasked Culprit in Neurodegenerative Diseases
2017
Ascorbic acid ameliorates oxidative damage induced by maternal low-level lead exposure in the hippocampus of rat pups during gestation and lactation
2011
Forebrain microglia from wild-type but not adult 5xFAD mice prevent amyloid-β plaque formation in organotypic hippocampal slice cultures
2015
The amyloid hypothesis of Alzheimer's disease at 25 years
2016 Standout
Comprehensive Review on Alzheimer’s Disease: Causes and Treatment
2020 Standout
Glycoproteomics
2022 StandoutNobel
Alzheimer's disease
2017 Standout
Pyrano[3,2-c]quinoline−6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and β-Amyloid-Directed Anti-Alzheimer Compounds
2009
Donepezil in Alzheimer's disease: From conventional trials to pharmacogenetics.
2007
Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase
2016 StandoutNobel
Overview of pharmacological activities ofAndrographis paniculataand its major compound andrographolide
2018 Standout
Neue Ziele für die Photopharmakologie
2016 StandoutNobel
Inflammation as a central mechanism in Alzheimer's disease
2018 Standout
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
New Tacrine–4-Oxo-4H-chromene Hybrids as Multifunctional Agents for the Treatment of Alzheimer’s Disease, with Cholinergic, Antioxidant, and β-Amyloid-Reducing Properties
2012
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Fucoxanthin, a Marine Carotenoid, Reverses Scopolamine-Induced Cognitive Impairments in Mice and Inhibits Acetylcholinesterase in Vitro
2016
Marine natural products
2018 Standout
Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health
2020 Standout
Religious Orders Study and Rush Memory and Aging Project
2018 Standout
The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease
2018 Standout
Metallic implant biomaterials
2014 Standout
Emerging Targets in Photopharmacology
2016 StandoutNobel
ROS Generation in Microglia: Understanding Oxidative Stress and Inflammation in Neurodegenerative Disease
2020
Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice
2017
Ngly1 −/− rats develop neurodegenerative phenotypes and pathological abnormalities in their peripheral and central nervous systems
2020
Oligomeropathies and pathogenesis of Alzheimer and Parkinson's diseases
2016
Animal systems in the development of treatments for Alzheimer's disease: challenges, methods, and implications
2012
Important Flavonoids and Their Role as a Therapeutic Agent
2020 Standout
Works of Hongjun Fu being referenced
Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin
2015
Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease
2017
Paeoniflorin inhibits the maturation and immunostimulatory function of allergen-induced murine dendritic cells
2014
Promising multifunctional anti-Alzheimer's dimer bis(7)-Cognitin acting as an activator of protein kinase C regulates activities of α-secretase and BACE-1 concurrently
2009
Novel Dimeric Acetylcholinesterase Inhibitor Bis(7)-tacrine, but Not Donepezil, Prevents Glutamate-induced Neuronal Apoptosis by Blocking N-Methyl-d-aspartate Receptors
2005
Synergistic Neuroprotection by Bis(7)-tacrine via Concurrent Blockade of N-Methyl-d-aspartate Receptors and Neuronal Nitric-Oxide Synthase
2007
Environmental Novelty Activates β2-Adrenergic Signaling to Prevent the Impairment of Hippocampal LTP by Aβ Oligomers
2013
Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia
2012
Oral administration of paeoniflorin attenuates allergic contact dermatitis by inhibiting dendritic cell migration and Th1 and Th17 differentiation in a mouse model
2015
MER5101, a Novel Aβ1-15:DT Conjugate Vaccine, Generates a Robust Anti-Aβ Antibody Response and Attenuates Aβ Pathology and Cognitive Deficits in APPswe/PS1ΔE9 Transgenic Mice
2013
Maternal low-level lead exposure reduces the expression of PSA-NCAM and the activity of sialyltransferase in the hippocampi of neonatal rat pups
2008
Paeoniflorin suppresses IL-6/Stat3 pathway via upregulation of Socs3 in dendritic cells in response to 1-chloro-2,4-dinitrobenze
2016
Pathologically Activated Neuroprotection via Uncompetitive Blockade of N-Methyl-d-aspartate Receptors with Fast Off-rate by Novel Multifunctional Dimer Bis(propyl)-cognitin
2010
A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
2018
scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses
2021
Aluminum-induced apoptosis in cultured cortical neurons and its effect on SAPK/JNK signal transduction pathway
2003
Selective vulnerability in neurodegenerative diseases
2018
Amyloid-β Immunotherapy for Alzheimers Disease
2010
Bis(7)‐tacrine attenuates β amyloid‐induced neuronal apoptosis by regulating L‐type calcium channels
2006
Neuroprotection via inhibition of nitric oxide synthase by bis(7)-tacrine
2006
Promising anti-Alzheimer’s dimer bis(7)-tacrine reduces β-amyloid generation by directly inhibiting BACE-1 activity
2007
Neuronal activity enhances tau propagation and tau pathology in vivo
2016
Primary Tr1 cells from metastatic melanoma eliminate tumor-promoting macrophages through granzyme B- and perforin-dependent mechanisms
2017
F‐box/ LRR ‐repeat protein 7 is genetically associated with Alzheimer's disease
2015