Hiroshi Shima

Accurate proteome-wide missense variant effect prediction with AlphaMissense

Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds

Nuclear Inhibitor of Protein Phosphatase-1 (NIPP1) Directs Protein Phosphatase-1 (PP1) to Dephosphorylate the U2 Small Nuclear Ribonucleoprotein Particle (snRNP) Component, Spliceosome-associated Protein 155 (Sap155)

The spiroketals containing a benzyloxymethyl moiety at C8 position showed the most potent apoptosis-inducing activity