Citation Impact
Citing Papers
The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain
2009 StandoutScience
RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription
2010 StandoutNobel
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
2011 StandoutScience
Chemical Changes Induced in DNA by Ionizing Radiation
1985
Hallmarks of Cancer: The Next Generation
2011 Standout
An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells
2015 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine
2011
Base-excision repair of oxidative DNA damage
2007 StandoutNature
Molecular cloning and functional analysis of a Schizosaccharomyces pombe homologue of Escherichia coli endonuclease III
1996
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Oxidative damage to DNA: Formation, measurement, and biological significance
1997
Synthetic DNA bending sequences increase the rate of in vitro transcription initiation at the Escherichia coli lac promoter
1991
DNA base damage induced by ionizing radiation recognized byEscherichia coli UvrABC nuclease but not Nth or Fpg proteins
1996
The Discovery of 5‐Formylcytosine in Embryonic Stem Cell DNA
2011
Mutagenicity, toxicity and repair of DNA base damage induced by oxidation
2003
A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII
2002
Ap endonucleases and dna glycosylases that recognize oxidative dna damage
1988
Selective Excision of 5-Carboxylcytosine by a Thymine DNA Glycosylase Mutant
2013
Reactions of oxyl radicals with DNA
1995
Carcinogen-mediated oxidant formation and oxidative DNA damage
1992
A quantitative model of human DNA base excision repair. I. mechanistic insights
2002
Substrate specificities and excision kinetics of DNA glycosylases involved in base-excision repair of oxidative DNA damage
2003
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
A Back-up Glycosylase in Nth1 Knock-out Mice Is a Functional Nei (Endonuclease VIII) Homologue
2002
Characterization of an Endonuclease IV 3′-5′ Exonuclease Activity
2003
The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death
2003
Reaction Mechanism of Human DNA Repair Excision Nuclease
1996 StandoutNobel
Biochemical Basis of DNA Replication Fidelity
1993
Repair activity of base and nucleotide excision repair enzymes for guanine lesions induced by nitrosative stress
2005
Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
2010
Proliferation-dependent expression of nuclear uracil-DNA glycosylase is mediated in part by E2F-4
2004
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
2010 StandoutNobel
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
The First Cellular Models Based on Frataxin Missense Mutations That Reproduce Spontaneously the Defects Associated with Friedreich Ataxia
2009
Repair of Dihydrouracil Supported by Base Excision Repair in mNTH1 Knock-out Cell Extracts
2002
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases
2006 StandoutNobel
The ‘A rule’ of mutagen specificity: A consequence of DNA polymerase bypass of non‐instructional lesions?
1991
A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity
1998
Alternative nucleotide incision repair pathway for oxidative DNA damage
2002 Nature
Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions
1998
Single Nucleotide Patch Base Excision Repair Is the Major Pathway for Removal of Thymine Glycol from DNA in Human Cell Extracts
2000
C → T mutagenesis and γ‐radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases
2005 StandoutNobel
DNA Damage and Oxygen Radical Toxicity
1988 StandoutScience
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Mutational specificity of alkylating agents and the influence of DNA repair
1990
Germline transmission of RNAi in mice
2003
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
The base excision repair pathway
1995
Purification and characterization of Escherichia coli endonuclease III from the cloned nth gene
1989
DNA glycosylases
1997
Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols
2002
Where transcription meets repair
1994 StandoutNobel
Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA
2009 StandoutNobel
Revealing the world of RNA interference
2004 StandoutNatureNobel
The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA
2001
Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells
2004
The enigma of endonuclease VIII
2003
Structure of a Duplex DNA Containing a Thymine Glycol Residue in Solution
1997
Yields of Radiation-induced Base Products in DNA: Effects of DNA Conformation and Gassing Conditions
1990
The Hallmarks of Aging
2013 Standout
Monomeric Base Damage Products from Guanine, Adenine, and Thymine Induced by Exposure of DNA to Ultraviolet Radiation
1995
The transcription factor, NFI/CTF plays a positive regulatory role in expression of the hSMUG1 gene
2003
The DNA replication fork can pass RNA polymerase without displacing the nascent transcript
1993 Nature
Mutational analysis of the damage-recognition and catalytic mechanism of human SMUG1 DNA glycosylase
2004
The effects of covalent additions of a psoralen on transcription byE. coliRNA polymerase
1987
Cell-cycle regulation, intracellular sorting and induced overexpression of the human NTH1 DNA glycosylase involved in removal of formamidopyrimidine residues from DNA
2000
Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA
2002
A specific partner for abasic damage in DNA
1999 Nature
Synthesis of stable-isotope enriched 5-methylpyrimidines and their use as probes of base reactivity in DNA
2002
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome
1990
Repair of the mutagenic DNA oxidation product, 5-formyluracil
2003
The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway
2004
Repairing DNA-methylation damage
2004
Purification and Characterization of Human NTH1, a Homolog ofEscherichia coli Endonuclease III
1998
Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins
2002
Characterization of Escherichia coli Endonuclease VIII
1997
A method for detecting abasic sites in living cells: Age-dependent changes in base excision repair
2000
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
1999 StandoutNobel
Base excision of oxidative purine and pyrimidine DNA damage in Saccharomyces cerevisiae by a DNA glycosylase with sequence similarity to endonuclease III from Escherichia coli.
1996
p53 Mutations in Human Cancers
1991 StandoutScience
Kinetic Analysis of an Efficient DNA-Dependent TNA Polymerase
2005 StandoutNobel
Highly sensitive apurinic/apyrimidinic site assay can detect spontaneous and chemically induced depurination under physiological conditions.
1998
Efficient DNA Cleavage with an Iron Complex without Added Reductant
2000 StandoutNobel
DNA excision-repair defect of xeroderma pigmentosum prevents removal of a class of oxygen free radical-induced base lesions.
1993 StandoutNobel
Is Sulfate Radical Really Generated from Peroxydisulfate Activated by Iron(II) for Environmental Decontamination?
2018 Standout
DNA?protein crosslinks: their induction, repair, and biological consequences
2005
Human Endonuclease III Acts Preferentially on DNA Damage Opposite Guanine Residues in DNA
2001
In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients
1997 StandoutNobel
New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase.
1994
CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing
2019
Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/apyrimidinic sites.
1990
Quality Control by DNA Repair
1999 StandoutScienceNobel
The LIM region of a presumptive Caenorhabditis elegans transcription factor is an iron-sulfur- and zinc-containing metallodomain.
1991 StandoutNobel
Oxidative Strand Scission of Nucleic Acids: Routes Initiated by Hydrogen Abstraction from the Sugar Moiety
1998
3, N 4 -ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase
1998
Transcription Arrest at an Abasic Site in the Transcribed Strand of Template DNA
2006
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts.
1994 StandoutNobel
Initiation of Base Excision Repair: Glycosylase Mechanisms and Structures
1999
Oxidative DNA damage: mechanisms, mutation, and disease
2003 Standout
Ancient DNA: extraction, characterization, molecular cloning, and enzymatic amplification.
1989 StandoutNobel
Repair and Genetic Consequences of Endogenous DNA Base Damage in Mammalian Cells
2004 StandoutNobel
Targeted Deletion of mNth1 Reveals a Novel DNA Repair Enzyme Activity
2002
Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°
1991 StandoutScienceNobel
DNA glycosylases in the base excision repair of DNA
1997
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA.
2003
1H,13C and15N nuclear magnetic resonance analysis and chemical features of the two main radical oxidation products of 2′-deoxyguanosine: oxazolone and imidazolone nucleosides
1996
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III
1997 StandoutNobel
HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease.
1994 StandoutNobel
Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase
1997 StandoutNobel
Enzymatic Processing of Radiation-Induced Free Radical Damage in DNA
1998
Hybridization properties of base-modified oligonucleotides within the double and triple helix motif
1998
Genetic effects of thymine glycol: site-specific mutagenesis and molecular modeling studies.
1989
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Removal of oxygen free-radical-induced 5′,8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells
2000 StandoutNobel
TNA Synthesis by DNA Polymerases
2003 StandoutNobel
Repair of DNA–polypeptide crosslinks by human excision nuclease
2006 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Oxidized, deaminated cytosines are a source of C → T transitions in vivo
1998
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
1991 StandoutNature
Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG
2000
Works of Hiroshi Ide being referenced
Influence of .alpha.-Deoxyadenosine on the Stability and Structure of DNA. Thermodynamic and Molecular Mechanics Studies
1995
Cloning and characterization of a mouse homologue (mnthl1) of Escherichia coli endonuclease III
1998
.alpha.-Deoxyadenosine, a Major Anoxic Radiolysis Product of Adenine in DNA, Is a Substrate for Escherichia coli Endonuclease IV
1994
Homologous Recombination but Not Nucleotide Excision Repair Plays a Pivotal Role in Tolerance of DNA-Protein Cross-links in Mammalian Cells
2009
A novel sensitive and specific assay for abasic sites, the most commonly produced DNA lesion
1992
In Vitro selection of sequence contexts which enhance bypass of abasic sites and tetrahydrofuran by T4 DNA polymerase holoenzyme 1 1Edited by J. M. Miller
1999
Enzymatic Repair of 5-Formyluracil
1999
Synthesis and damage specificity of a novel probe for the detection of abasic sites in DNA
1993
Isolation and Characterization of Endonuclease VIII from Escherichia coli
1994
Recognition of Formamidopyrimidine by Escherichia coli and Mammalian Thymine Glycol Glycosylases
2000
Novel Modification of 5-Formyluracil by Cysteine Derivatives in Aqueous Solution
1998
DNA-Protein Cross-link Formation Mediated by Oxanine
2003
Differential Specificity of Human and Escherichia coli Endonuclease III and VIII Homologues for Oxidative Base Lesions
2004
Replication of DNA Templates Containing the .alpha.-Anomer of Deoxyadenosine, a Major Adenine Lesion Produced by Hydroxyl Radicals
1994
DNA substrates containing defined oxidative base lesions and their application to study substrate specificities of base excision repair enzymes
2001
Oxidation of Thymine to 5-Formyluracil in DNA Promotes Misincorporation of dGMP and Subsequent Elongation of a Mismatched Primer Terminus by DNA Polymerase
2001
Distinct Repair Activities of Human 7,8-Dihydro-8-oxoguanine DNA Glycosylase and Formamidopyrimidine DNA Glycosylase for Formamidopyrimidine and 7,8-Dihydro-8-oxoguanine
2000 StandoutNobel
Effects of a Guanine-derived Formamidopyrimidine Lesion on DNA Replication
2002
Enzymatic Repair of 5-Formyluracil
1999
Isolation and Characterization of Diazoate Intermediate upon Nitrous Acid and Nitric Oxide Treatment of 2‘-Deoxycytidine
1999
Products of the Reaction between a Diazoate Derivative of 2‘-Deoxycytidine and l -Lysine and Its Implication for DNA−Nucleoprotein Cross-Linking by NO or HNO2
2000
Establishment of expanded and streamlined pipeline of PITCh knock-in – a web-based design tool for MMEJ-mediated gene knock-in, PITCh designer, and the variations of PITCh, PITCh-TG and PITCh-KIKO
2017
Comparison of Substrate Specificities of Escherichia coli Endonuclease III and Its Mouse Homologue (mNTH1) Using Defined Oligonucleotide Substrates
2000
Mechanistic studies on the formation of aminoxyl radicals from 5,5-dimethyl-1-pyrroline-N-oxide in Fenton systems. Characterization of key precursors giving rise to background ESR signals
1992
Radiation-induced Reduction of Thymine in Aqueous Solution
1982
Deglycosylation Susceptibility and Base-Pairing Stability of 2‘-Deoxyoxanosine in Oligodeoxynucleotide
1997
α-Anomeric Deoxynucleotides, Anoxic Products of Ionizing Radiation, Are Substrates for the Endonuclease IV-Type AP Endonucleases
2004
Mammalian 5-Formyluracil−DNA Glycosylase. 1. Identification and Characterization of a Novel Activity That Releases 5-Formyluracil from DNA
2003
Processing of DNA base damage by DNA polymerases. Dihydrothymine and beta-ureidoisobutyric acid as models for instructive and noninstructive lesions
1991
Human DNA Glycosylases Involved in the Repair of Oxidatively Damaged DNA
2004
Identification and Characterization of a Reaction Product of 2‘-Deoxyoxanosine with Glycine
2000
Mammalian 5-Formyluracil−DNA Glycosylase. 2. Role of SMUG1 Uracil−DNA Glycosylase in Repair of 5-Formyluracil and Other Oxidized and Deaminated Base Lesions
2003
Thymine glycols and urea residues in M13 DNA constitute replicative blocksin vitro
1985
Isolation and Characterization of a Novel Product, 2‘-Deoxyoxanosine, from 2‘-Deoxyguanosine, Oligodeoxynucleotide, and Calf Thymus DNA Treated by Nitrous Acid and Nitric Oxide
1996
Substrate Specificity of Human Methylpurine DNA N-Glycosylase
2000
Synthesis of dihydrothymidine and thymidine glycol 5'-triphosphates and their ability to serve as substrates for Escherichia coli DNA polymerase I
1987
Radiation-induced Hydroxylation of Thymine Promoted by Electron-affinic Compounds
1983