Citation Impact
Citing Papers
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
2009 StandoutScience
Computational design of a protein crystal
2012
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Stimulation of P2 purinergic receptors induces the release of eosinophil cationic protein and interleukin‐8 from human eosinophils
2003
Necroptosis and its role in inflammation
2015 StandoutNature
Reversal of Chemoresistance of Lymphoma Cells by Antisense-Mediated Reduction ofbcl-2 Gene Expression
1994
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
2004 StandoutNature
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Glutathione Levels Discriminate between Oxidative Stress and Transforming Growth Factor-β Signaling in Activated Rat Hepatic Stellate Cells
1999
Nucleotide signalling during inflammation
2014 StandoutNature
Characterization of the ribonuclease activity on the skin surface
2006
IL3-Dependent Cells Die by Apoptosis on Removal of their Growth Factor
1991
Hydrogen peroxide mediates amyloid β protein toxicity
1994 Standout
A T cell-dependent experimental liver injury in mice inducible by concanavalin A.
1992
Sensitizing Anthrax Lethal Toxin-resistant Macrophages to Lethal Toxin-induced Killing by Tumor Necrosis Factor-α
2003 StandoutNobel
Accurate design of co-assembling multi-component protein nanomaterials
2014 StandoutNatureNobel
Laminin-1 and epidermal growth factor family members co-stimulate fetal pancreas cell proliferation and colony formation
2005
CD4-positive T lymphocytes are required for the generation of the primary but not the secondary CD8-positive cytolytic T lymphocyte response to herpes simplex virus in C57BL/6 mice
1991
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
2012 Standout
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Development of a virus-mimicking nanocarrier for drug delivery systems: The bio-nanocapsule
2015
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice.
1991
Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death
1996 Standout
A polymeric form of fibronectin has antimetastatic effects against multiple tumor types
1996
The tissue distribution of tumor necrosis factor biosynthesis during endotoxemia.
1992 StandoutNobel
Virus entry: molecular mechanisms and biomedical applications
2004
Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators
2004 StandoutNobel
The Fas Death Factor
1995 StandoutScience
Myocardial Reperfusion Injury
2007 Standout
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Focal expression of interleukin-2 does not break unresponsiveness to "self" (viral) antigen expressed in beta cells but enhances development of autoimmune disease (diabetes) after initiation of an anti-self immune response.
1995 StandoutNobel
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
2004
Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination
2016
Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species
1993 StandoutScience
The TNF and TNF Receptor Superfamilies
2001 Standout
Programmed Cell Death in Animal Development
1997 Standout
Antimicrobial peptides of multicellular organisms
2002 StandoutNature
Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L
2011 StandoutNobel
Evaluation of the Inactivation of Infectious Herpes Simplex Virus by Host-Defense Peptides
2000
Subcellular targeting strategies for drug design and delivery
2009
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill
1989 Standout
A Single Bolus of a Long-acting Erythropoietin Analogue Darbepoetin Alfa in Patients with Acute Myocardial Infarction: A Randomized Feasibility and Safety Study
2006
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Recombinant human betacellulin promotes the neogenesis of beta-cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion.
2000
Divergent signalling via APO-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death.
1994
Activation of human eosinophils via P2 receptors: novel findings and future perspectives
2005
Efficient in Vitro Encapsulation of Protein Cargo by an Engineered Protein Container
2011
A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma
1991 StandoutScience
Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis
1995 StandoutScience
Bispecific Antibodies as Novel Bioconjugates
1998
Inhibition of Caspases Increases the Sensitivity of L929 Cells to Necrosis Mediated by Tumor Necrosis Factor
1998
Supramolecular Double-Helix Formation by Diastereoisomeric Conformations of Configurationally Enantiomeric Macrocycles
2016 StandoutNobel
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation.
1992
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
Apoptosis in the Pathogenesis and Treatment of Disease
1995 StandoutScience
Proposed three-dimensional structure for the cellular prion protein.
1994 StandoutNobel
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero
1998 StandoutNobel
Functional mapping of disease susceptibility loci using cell biology
2006 StandoutNobel
A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice
2005 StandoutNobel
Importance of disulfide linkage for constructing the biologically active human interleukin-2
1987
The Ribonuclease A Superfamily in Humans: Canonical RNases as the Buttress of Innate Immunity
2016
pVHL 19 is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation
1998 StandoutNobel
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
1995 Standout
RNase L Mediates the Antiviral Effect of Interferon through a Selective Reduction in Viral RNA during Encephalomyocarditis Virus Infection
1998
Directed Evolution of a Protein Container
2011 Science
Structure-Activity Studies of Interleukin-2
1986 Science
Design of protein crystals in the development of solid biomaterials
2015
Antibody–Enzyme Fusion Proteins for Cancer Therapy
2011
Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells.
1996 StandoutNobel
Integration of Porous Coordination Polymers and Gold Nanorods into Core–Shell Mesoscopic Composites toward Light-Induced Molecular Release
2013 StandoutNobel
Multiple event activation of a generic prodrug trigger by antibody catalysis
1999 StandoutNobel
Dual Signaling of the Fas Receptor: Initiation of Both Apoptotic and Necrotic Cell Death Pathways
1998
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Protein Assembly by Design
2021
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
DNA−Gold Nanorod Conjugates for Remote Control of Localized Gene Expression by near Infrared Irradiation
2006
Programmed cell death and Bcl-2 protection in the absence of a nucleus.
1994
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel
Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces
2015 StandoutScienceNobel
Interleukin-2: Inception, Impact, and Implications
1988 StandoutScience
Works of Hiroko Tada being referenced
Nanoparticles for the delivery of genes and drugs to human hepatocytes
2003
‘Crystal lattice engineering,’ an approach to engineer protein crystal contacts by creating intermolecular symmetry: Crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines
2007
Growth inhibition of mammalian cells by eosinophil cationic protein
2002
Characterization of bio-nanocapsule as a transfer vector targeting human hepatocyte carcinoma by disulfide linkage modification
2006
Human Betacellulin, a Member of the EGF Family Dominantly Expressed in Pancreas and Small Intestine, is Fully Active in a Monomeric Form
1996
High Serum Erythropoietin Level Is Associated With Smaller Infarct Size in Patients With Acute Myocardial Infarction Who Undergo Successful Primary Percutaneous Coronary Intervention
2005
Tissue-Specific Expression of Pancreatic-Type RNases and RNase Inhibitor in Humans
1997
The specific delivery of proteins to human liver cells by engineered bio‐nanocapsules
2005
Bispecific Antibody-Producing Hybrid Hybridoma and Its Use in One-Step Immunoassays for Human Lymphotoxin
1989
Comparison of the biological properties of purified natural and recombinant human interleukin-2
1985
An improved colorimetric assay for interleukin 2
1986
Processing and juxtacrine activity of membrane-anchored betacellulin
1999
Immunohistochemical Localization of Betacellulin, a New Member of the EGF Family, in Normal Human Pancreas and Islet Tumor Cells.
1999