Citation Impact

Citing Papers

On the relationship between folding and chemical landscapes in enzyme catalysis
2008 StandoutNobel
AB INITIO QUANTUM CHEMICAL AND MIXED QUANTUM MECHANICS/MOLECULAR MECHANICS (QM/MM) METHODS FOR STUDYING ENZYMATIC CATALYSIS
2005
Cytochrome P450 Compound I: Capture, Characterization, and C-H Bond Activation Kinetics
2010 Science
A Dynamic Knockout Reveals That Conformational Fluctuations Influence the Chemical Step of Enzyme Catalysis
2011 Science
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions
2011 StandoutNobel
Intermediates in the reaction of substrate‐free cytochrome P450cam with peroxy acetic acid
2000
Mediation of Unusually High Concentrations of 1,25-Dihydroxyvitamin D in HomozygousklothoMutant Mice by Increased Expression of Renal 1α-Hydroxylase Gene
2002
Metal-Substituted Protein MRI Contrast Agents Engineered for Enhanced Relaxivity and Ligand Sensitivity
2010 StandoutNobel
Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo
2013 StandoutNobel
Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation
1999 StandoutNatureNobel
Stopped-flow spectrophotometric analysis of intermediates in the peroxo-dependent inactivation of cytochrome P450 by aldehydes
2000
Highly Efficient Visible‐Light Driven Photochromism: Developments towards a Solid‐State Molecular Switch Operating through a Triplet‐Sensitised Pathway
2011
Quinone-Annonaceous Acetogenins: Synthesis and Complex I Inhibition Studies of a New Class of Natural Product Hybrids
2001
Kinetic and Spectroscopic Characterization of a Hydroperoxy Compound in the Reaction of Native Myoglobin with Hydrogen Peroxide
2003
Spectroscopic studies of peroxyacetic acid reaction intermediates of cytochrome P450cam and chloroperoxidase
2002
Isotope labeling methods for studies of excited protein states by relaxation dispersion NMR spectroscopy
2009
C H bond activation in heme proteins: the role of thiolate ligation in cytochrome P450
2009
Measurement of carbonyl chemical shifts of excited protein states by relaxation dispersion NMR spectroscopy: comparison between uniformly and selectively 13C labeled samples
2008
Computational Enzyme Design
2013 StandoutNobel
Protein dynamics and conformational disorder in molecular recognition
2009
Artificial enzymes based on supramolecular scaffolds
2012
Vitamin D Deficiency
2007 Standout
Kinetic Characterization of Mitochondrial Complex I Inhibitors Using Annonaceous Acetogenins
1999
Single‐Molecule Spin Switch Based on Voltage‐Triggered Distortion of the Coordination Sphere
2015 StandoutNobel
Three Bits Eight States Photochromic Recording and Nondestructive Readout by Using IR Light
2004
Thermophilic cytochrome P450 enzymes
2005
Kinetic Characterization of Compound I Formation in the Thermostable Cytochrome P450 CYP119
2002
Three-state photochromic switching in a silyl bridged diarylethene dimer
2007 StandoutNobel
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
CPMG relaxation dispersion NMR experiments measuring glycine 1Hα and 13Cα chemical shifts in the ‘invisible’ excited states of proteins
2009
Nanoporous Carbohydrate Metal–Organic Frameworks
2011 StandoutNobel
Nanoparticles functionalised with reversible molecular and supramolecular switches
2010 StandoutNobel
Quantum chemical studies of methane monooxygenase: comparision with P450
2002
Solution structure of a minor and transiently formed state of a T4 lysozyme mutant
2011 StandoutNatureNobel
Klotho: a fundamental regulator of aging
2002
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Photoinduced Memory Effect in a Redox Controllable Bistable Mechanical Molecular Switch
2012 StandoutNobel
Natural Product Hybrids as New Leads for Drug Discovery
2003 Standout
Vitamin D
2005
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
Tyrosine Radical Formation in the Reaction of Wild Type and Mutant Cytochrome P450cam with Peroxy Acids
2004
Annonaceous Acetogenins: The Hydroxyl Groups and THF Rings Are Crucial Structural Elements for Targeting the Mitochondria, Demonstration with the Synthesis of Fluorescent Squamocin Analogues
2005
Calculation of the electronic structure and spectra of model cytochrome P450 compound I
2001
Klotho converts canonical FGF receptor into a specific receptor for FGF23
2006 StandoutNature
Using relaxation dispersion NMR spectroscopy to determine structures of excited, invisible protein states
2008
Oxidizing species in the mechanism of cytochrome P450
2002
Allosteric regulation and catalysis emerge via a common route
2008
Improved Cyclopropanation Activity of Histidine‐Ligated Cytochrome P450 Enables the Enantioselective Formal Synthesis of Levomilnacipran
2014 StandoutNobel
Charge transport through molecular switches
2010
Oxidizing intermediates in cytochrome P450 model reactions
2004
Cancer-related inflammation
2008 StandoutNature
Reactive Intermediates in Cytochrome P450 Catalysis
2013
Crystalline solids
2001
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
2011 StandoutNature
Models and mechanisms of O‐O bond activation by cytochrome P450
2004
The Lipid Whisker Model of the Structure of Oxidized Cell Membranes
2007
Engineered Alkane‐Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties
2007 StandoutNobel
Cytochrome P450: Structure, function, and generation of reactive oxygen species
1995
The status of high-valent metal oxo complexes in the P450 cytochromes
2006
Accurate Measurement of Alpha Proton Chemical Shifts of Excited Protein States by Relaxation Dispersion NMR Spectroscopy
2009
Cytochrome P450-Catalyzed Hydroxylation of Mechanistic Probes that Distinguish between Radicals and Cations. Evidence for Cationic but Not for Radical Intermediates
2000
Pillar[5]arene as a Co-Factor in Templating Rotaxane Formation
2013 StandoutNobel
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Single-Molecule Junctions Based on Nitrile-Terminated Biphenyls: A Promising New Anchoring Group
2010 StandoutNobel
Free-Energy Landscape of Enzyme Catalysis
2008
Catalytic iron-carbene intermediate revealed in a cytochrome c carbene transferase
2018 StandoutNobel
Tuning P450 Enzymes as Oxidation Catalysts
2012
Theoretical investigation on photochromic diarylethene: A short review
2008
Redox-Controlled Selective Docking in a [2]Catenane Host
2013 StandoutNobel
Active transition metal oxo and hydroxo moieties in nature's redox, enzymes and their synthetic models: Structure and reactivity relationships
2010
Hydrocarbon Hydroxylation by Cytochrome P450 Enzymes
2009
Heme Enzyme Structure and Function
2014
Proton-Transfer Dynamics in the Activation of Cytochrome P450eryF
2002
Hydroxylation of Camphor by Reduced Oxy-Cytochrome P450cam:  Mechanistic Implications of EPR and ENDOR Studies of Catalytic Intermediates in Native and Mutant Enzymes
2001
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins
2017
Inflammatory Cells and Cancer
2001
Synthesis and Inhibition Mechanism of Δlac-Acetogenins, a Novel Type of Inhibitor of Bovine Heart Mitochondrial Complex I
2004
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Pentalenolactone Biosynthesis. Molecular Cloning and Assignment of Biochemical Function to PtlI, a Cytochrome P450 of Streptomyces avermitilis
2006 StandoutNobel
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Resonance Raman Spectroscopic Studies of Hydroperoxo-Myoglobin at Cryogenic Temperatures
2003
A Solution-Phase Bifunctional Catalyst for Lithium–Oxygen Batteries
2014 StandoutNobel
Temperature Gating of the Ring‐Opening Process in Diarylethene Molecular Switches
2007 StandoutNobel
Annonaceous Acetogenins:  Recent Progress
1999 Standout
Driving Unidirectional Molecular Rotary Motors with Visible Light by Intra- And Intermolecular Energy Transfer from Palladium Porphyrin
2012 StandoutNobel
Searching for the Second Oxidant in the Catalytic Cycle of Cytochrome P450:  A Theoretical Investigation of the Iron(III)-Hydroperoxo Species and Its Epoxidation Pathways
2002
Cytochrome P450CAM Enzymatic Catalysis Cycle:  A Quantum Mechanics/Molecular Mechanics Study
2004
Hybridnaturstoffe: Design, Synthese und biologische Untersuchung von Chinon-Annonin-Acetogeninen
2000
Enzyme millisecond conformational dynamics do not catalyze the chemical step
2009 StandoutNobel
Theoretical Perspective on the Structure and Mechanism of Cytochrome P450 Enzymes
2005
The Elusive Oxidant Species of Cytochrome P450 Enzymes:  Characterization by Combined Quantum Mechanical/Molecular Mechanical (QM/MM) Calculations
2002
Peripheral heme substituents control the hydrogen-atom abstraction chemistry in cytochromes P450
2003
Epoxidation of olefins by cytochrome P450: Evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant
1998
Regio- and Enantioselective Alkane Hydroxylation with Engineered Cytochromes P450 BM-3
2003 StandoutNobel
Heme-Containing Oxygenases
1996 Standout
Mechanically Stabilized Tetrathiafulvalene Radical Dimers
2011 StandoutNobel
Alternate Heme Ligation Steers Activity and Selectivity in Engineered Cytochrome P450-Catalyzed Carbene-Transfer Reactions
2018 StandoutNobel
Solution-Phase Mechanistic Study and Solid-State Structure of a Tris(bipyridinium radical cation) Inclusion Complex
2011 StandoutNobel
Raman Evidence for a Weakened O−O Bond in Mononuclear Low-Spin Iron(III)−Hydroperoxides
1998 StandoutNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Current Understanding of the Molecular Actions of Vitamin D
1998
Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site
2023 StandoutNobel
Carbon Dioxide Capture in Metal–Organic Frameworks
2011 Standout
Redox Control of the Binding Modes of an Organic Receptor
2015 StandoutNobel
Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination
2014 StandoutNobel
Radically Enhanced Molecular Switches
2012 StandoutNobel
Structure and Chemistry of Cytochrome P450
2005 Standout
Structural Reorganization and Preorganization in Enzyme Active Sites: Comparisons of Experimental and Theoretically Ideal Active Site Geometries in the Multistep Serine Esterase Reaction Cycle
2008
Nonnative Interactions in the FF Domain Folding Pathway from an Atomic Resolution Structure of a Sparsely Populated Intermediate: An NMR Relaxation Dispersion Study
2011 StandoutNobel
Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450
2015 StandoutNobel

Works of Hiroko Shimada being referenced

The mechanism of rate-limiting motions in enzyme function
2007
Essential structural factors of annonaceous acetogenins as potent inhibitors of mitochondrial complex I
1998
THE LOCALISATIONS IN LIPOSOMAL MEMBRANES OF THE TETRAHYDROFURAN RING MOIETIES OF THE ANNONACEOUS ACETOGENINS, ANNONACIN AND SYLVATICIN, AS DETERMINED BY1H NMR SPECTROSCOPY
1998
Evidence for Compound I Formation in the Reaction of Cytochrome-P450cam with m-Chloroperbenzoic Acid
1994
Pressure Effect on Phase Transitions in Hexamethylbenzene Crystals
1999
Cloning and expression of rat 25-hydroxyvitamin D 3 -1α-hydroxylase cDNA
1997
Temperature- and Pressure-Induced Phase Transition in Tetrafluoro-1,4-benzoquinone Crystal
1999
Membrane Conformations and Their Relation to Cytotoxicity of Asimicin and Its Analogues
1998
Raman spectroscopic study on photochromic reaction of a diarylethene derivative
2002
Rankless by CCL
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