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Citing Papers
The Caenorhabditis elegans vulval morphogenesis gene sqv - 4 encodes a UDP-glucose dehydrogenase that is temporally and spatially regulated
2002 StandoutNobel
Visualizing enveloping layer glycans during zebrafish early embryogenesis
2010 StandoutNobel
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation
2003 StandoutNobel
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
Carbohydrate-modifying Sulfotransferases: Structure, Function, and Pathophysiology
2001
More to “heparin” than anticoagulation
1994
Interfering with UDP-GlcNAc Metabolism and Heparan Sulfate Expression Using a Sugar Analogue Reduces Angiogenesis
2013
Heparanase, a potential regulator of cell–matrix interactions
2000
Regulated Diversity of Heparan Sulfate
1998
Domain Structure of Heparan Sulfates from Bovine Organs
1996
An Animal Cell Mutant Defective in Heparan Sulfate Hexuronic Acid 2- -Sulfation
1996
Interaction of Heparan Sulfate from Mammary Cells with Acidic Fibroblast Growth Factor (FGF) and Basic FGF
1998
Sulfotransferases and sulfated oligosaccharides
2002
Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's β-secretase
2003
Syndecans: multifunctional cell-surface co-receptors
1997
Stimulation of fibroblast growth factor receptor-1 occupancy and signaling by cell surface-associated syndecans and glypican.
1996
Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor.
1994
Enzyme interactions in heparan sulfate biosynthesis: Uronosyl 5-epimerase and 2- O -sulfotransferase interact in vivo
2001
A Visualizable Chain‐Terminating Inhibitor of Glycosaminoglycan Biosynthesis in Developing Zebrafish
2014 StandoutNobel
Function and Structure of a Prokaryotic Formylglycine-generating Enzyme
2008 StandoutNobel
Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated?
1997
Long‐Lived Engineering of Glycans to Direct Stem Cell Fate
2014
Demonstration of glycosaminoglycans in Caenorhabditis elegans
1999
The Degradation of Human Endothelial Cell-derived Perlecan and Release of Bound Basic Fibroblast Growth Factor by Stromelysin, Collagenase, Plasmin, and Heparanases
1996
Characterization of Heparin and Heparan Sulfate Domains Binding to the Long Splice Variant of Platelet-derived Growth Factor A Chain
1997
Heparin-Protein Interactions
2002 Standout
Biosynthesis of heparan sulfate on beta-D-xylosides depends on aglycone structure.
1994
4-Deoxy-4-fluoro-xyloside derivatives as inhibitors of glycosaminoglycan biosynthesis
2010
FGF Binding and FGF Receptor Activation by Synthetic Heparan-Derived Di- and Trisaccharides
1995 Science
Exploring the glycan repertoire of genetically modified mice by isolation and profiling of the major glycan classes and nano-NMR analysis of glycan mixtures
2000
Characterization of the Stromal Cell-derived Factor-1α-Heparin Complex
2001
The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection
2007 StandoutNobel
Glycosaminoglycan-protein interactions: definition of consensus sites in glycosaminoglycan binding proteins
1998
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
The Stem Region of the Sulfotransferase GlcNAc6ST-1 Is a Determinant of Substrate Specificity
2004 StandoutNobel
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase
1998
Molecular Cloning and Expression of a Novel Chondroitin 6-O-Sulfotransferase
2000
Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour
2005 StandoutNatureNobel
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Heparin and heparan sulfate: structure and function
2002
Sulfatases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
In the clutches of proteoglycans: how does heparan sulfate regulate FGF binding?
1995
Inhibition of the glycosylation and alteration in the intracellular trafficking of mucins and other glycoproteins by galnaca-o-bn in mucosal cell lines: an effect mediated through the intracellular synthesis of complex galnaca-o-bn oligosaccharides
2001
Antibody-based assay for N-deacetylase activity of heparan sulfate/heparin N-deacetylase/N-sulfotransferase (NDST): novel characteristics of NDST-1 and -2
2002
Small‐Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In‐line Screening of an Optically Encoded Library
2010 StandoutNobel
Characterization of the Structure and Dynamics of a Near-native Equilibrium Intermediate in the Unfolding Pathway of an All β-Barrel Protein
2002
Glycosylation in Cellular Mechanisms of Health and Disease
2006 Standout
Identification of an N-acetylglucosamine-6-O-sulfotransferase activity specific to lymphoid tissue: an enzyme with a possible role in lymphocyte homing
1998 StandoutNobel
Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila
2002
The Hallmarks of Cancer
2000 Standout
Specificity studies on the heparin lyases from Flavobacterium heparinum
1993
VEGF receptor signalling ? in control of vascular function
2006 Standout
Sulfotransferases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
Purification of Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase
1996
Sulfation of N-Acetylglucosamine by Chondroitin 6-Sulfotransferase 2 (GST-5)
2000 StandoutNobel
Glycomic survey mapping of zebrafish identifies unique sialylation pattern
2005
Mouse chondroitin 6-sulfotransferase: molecular cloning, characterization and chromosomal mapping
1998
Metabolic Delivery of Ketone Groups to Sialic Acid Residues
1998 StandoutNobel
Specificities of heparan sulphate proteoglycans in developmental processes
2000 Nature
5′-Adenosinephosphosulfate Lies at a Metabolic Branch Point in Mycobacteria
2002 StandoutNobel
Enzymatic Modification of Heparan Sulfate on a Biochip Promotes Its Interaction with Antithrombin III
2000
Negative regulation of transforming growth factor-β by the proteoglycan decorin
1990 StandoutNature
Enzymatic sulfation of galactose residue of keratan sulfate by chondroitin 6-sulfotransferase
1996
Spatially Restricted Expression of pipe in the Drosophila Egg Chamber Defines Embryonic Dorsal–Ventral Polarity
1998
Molecular cloning and expression of human chondroitin 6-sulfotransferase
1998
Conserved structural motifs in the sulfotransferase family
1998
Multiple Interactions of HIV-I Tat Protein with Size-defined Heparin Oligosaccharides
1999
Molecular Cloning and Expression of Chick Chondrocyte Chondroitin 6-Sulfotransferase
1995
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
Strategies for Targeting Protein–Protein Interactions With Synthetic Agents
2005
Chemical Approaches To Perturb, Profile, and Perceive Glycans
2009 StandoutNobel
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Human Homolog of Caenorhabditis elegans sqv-3 Gene Is Galactosyltransferase I Involved in the Biosynthesis of the Glycosaminoglycan-Protein Linkage Region of Proteoglycans
1999
Mucin Granule Intraluminal Organization in Living Mucous/Goblet Cells
2005 StandoutNobel
Golgi Localization of Carbohydrate Sulfotransferases Is a Determinant of L-selectin Ligand Biosynthesis
2003 StandoutNobel
Substrate Specificity of Heparanases from Human Hepatoma and Platelets
1998
Recognition of Hyaluronan Released in Sterile Injury Involves a Unique Receptor Complex Dependent on Toll-like Receptor 4, CD44, and MD-2
2007 StandoutNobel
Glycocalyx Engineering with a Recycling Glycopolymer that Increases Cell Survival In Vivo
2015 StandoutNobel
Multiple Isoforms of Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase
1999
Are Complex Behaviors Specified by Dedicated Regulatory Genes? Reasoning from Drosophila
2001 StandoutNobel
Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice
1999 StandoutNobel
Genetic analysis of functions for cell surface proteoglycans
1998
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Order out of complexity – protein structures that interact with heparin
2001
Molecular Cloning and Characterization of Human Keratan Sulfate Gal-6-Sulfotransferase
1997
Molecular Cloning and Characterization of anN-Acetylglucosamine-6-O-sulfotransferase
1998
Anemia of Chronic Disease
2005 Standout
Carbohydrate sulfotransferases: mediators of extracellular communication
1999 StandoutNobel
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling
2003
Heparan Sulfate Biosynthesis
2012
Laminins, via heparan sulfate proteoglycans, participate in zebrafish myotome morphogenesis by modulating the pattern of Bmp responsiveness
2010
The Molecular Diversity of Glycosaminoglycans Shapes Animal Development
2006
The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development
2002 StandoutNobel
Molecular insights into renal interstitial fibrosis.
1996
Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4.
1993
Chemical Glycobiology
2001 StandoutScienceNobel
Heparin: a potent inhibitor of hepcidin expression in vitro and in vivo
2010
NMR solution conformation of heparin-derived hexasaccharide
1997
SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP- N - acetylgalactosamine, and UDP-galactose
2001 StandoutNobel
Cell surface syndecan-1 on distinct cell types differs in fine structure and ligand binding of its heparan sulfate chains.
1994
Structural analysis of chick-embryo cartilage proteoglycan by selective degradation with chondroitin lyases (chondroitinases) and endo-β-d -galactosidase (keratanase)
1980
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Estradiol beta-D-xyloside, an efficient primer for heparan sulfate biosynthesis.
1991
Ketone Isosteres of 2-N-Acetamidosugars as Substrates for Metabolic Cell Surface Engineering
2001 StandoutNobel
Purification of chondroitin 6-sulfotransferase secreted from cultured chick embryo chondrocytes.
1993
NMR solution conformation of heparin-derived tetrasaccharide
1996
Heparan sulfate: a piece of information
1996
Order Out of Chaos: Assembly of Ligand Binding Sites in Heparan Sulfate
2002
Secretion of chondroitin 6-sulfotransferase and chondroitin 4-sulfotransferase from cultured chick embryo chondrocytes
1991
Differences in the susceptibility of herpes simplex virus types 1 and 2 to modified heparin compounds suggest serotype differences in viral entry
1996
Strategien zur Modulation von Protein‐Protein‐Wechselwirkungen mit synthetischen Substanzen
2005
A sulfated metabolite produced bystf3negatively regulates the virulence ofMycobacteriumtuberculosis
2006 StandoutNobel
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
Development of a Peptide Inhibitor of Hyaluronan-Mediated Leukocyte Trafficking
2000
Investigating Cellular Metabolism of Synthetic Azidosugars with the Staudinger Ligation
2002 StandoutNobel
Expression in Escherichia coli, purification and characterization of heparinase I from Flavobacterium heparinum
1996
Aberrant Splicing and Altered Spatial Expression Patterns in fruitless Mutants of Drosophila melanogaster
2000 StandoutNobel
Extracellular RNA mediates endothelial-cell permeability via vascular endothelial growth factor
2007
Long‐Lived Engineering of Glycans to Direct Stem Cell Fate
2014
Differential Carbohydrate Recognition of Two GlcNAc-6-sulfotransferases with Possible Roles in L-Selectin Ligand Biosynthesis
2000 StandoutNobel
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Inhibition of mucin glycosylation by aryl-N-acetyl-α-galactosaminides in human colon cancer cells
1989
Functional analysis of fruitless gene expression by transgenic manipulations of Drosophila courtship
2005 StandoutNobel
Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library
2000 StandoutNobel
Functions of heparan sulfate proteoglycans in cell signaling during development
2004
Functions of Cell Surface Heparan Sulfate Proteoglycans
1999 Standout
Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach
2002 StandoutNobel
Adherence of pilus- Opa+ gonococci to epithelial cells in vitro involves heparan sulfate.
1995
Frequent expression of CCR4 in adult T-cell leukemia and human T-cell leukemia virus type 1–transformed T cells
2002
Cleavage of Amyloid-β Precursor Protein and Amyloid-β Precursor-like Protein by BACE 1
2004 StandoutNobel
Potentiation and Inhibition of bFGF Binding by Heparin: A Model for Regulation of Cellular Response
2000
Works of Hiroko Habuchi being referenced
6-O-Sulfation of Heparan Sulfate Differentially Regulates Various Fibroblast Growth Factor-dependent Signalings in Culture
2008
Characterization of Growth Factor-binding Structures in Heparin/Heparan Sulfate Using an Octasaccharide Library
2004
Heparan sulfate is required for bone morphogenetic protein-7 signaling
2003
Structure of a heparan sulphate oligosaccharide that binds to basic fibroblast growth factor
1992
Mice Deficient in Heparan Sulfate 6-O-Sulfotransferase-1
2010
Turnover of Heparan Sulfate Depends on 2-O-Sulfation of Uronic Acids
1997
Purification and Characterization of Heparan Sulfate 2-Sulfotransferase from Cultured Chinese Hamster Ovary Cells
1996
Substrate Specificity of the Heparan Sulfate Hexuronic Acid 2-O-Sulfotransferase
2001
Basic fibroblast growth factor-binding domain of heparan sulfate in the human glomerulosclerosis and renal tubulointerstitial fibrosis.
1994
Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling
2002
Heparan sulfate proteoglycan on leukemic cells is primarily involved in integrin triggering and its mediated adhesion to endothelial cells.
1996
Biosynthesis of Heparan Sulfate and Heparin. How Are the Multifunctional Glycosaminoglycans Built up?
1998
Widespread Expression of Chondroitin Sulfate-type Serglycins with CD44 Binding Ability in Hematopoietic Cells
1997
Purification and Characterization of Heparan Sulfate 6-Sulfotransferase from the Culture Medium of Chinese Hamster Ovary Cells
1995
Molecular Cloning and Expression of Chondroitin 4-Sulfotransferase
2000
Drosophila Heparan Sulfate 6-O-Sulfotransferase (dHS6ST) Gene
2001
Molecular Cloning and Expression of Chinese Hamster Ovary Cell Heparan-sulfate 2-Sulfotransferase
1997
Solution structure of human acidic fibroblast growth factor and interaction with heparin-derived hexasaccharide
1999
Sulfation pattern in glycosaminoglycan: Does it have a code?
2004
The Occurrence of Three Isoforms of Heparan Sulfate 6-O-Sulfotransferase Having Different Specificities for Hexuronic Acid Adjacent to the TargetedN-Sulfoglucosamine
2000
Heparin Regulates Vascular Endothelial Growth Factor165-dependent Mitogenic Activity, Tube Formation, and Its Receptor Phosphorylation of Human Endothelial Cells
2005
Oligosaccharide Library-based Assessment of Heparan Sulfate 6-O-Sulfotransferase Substrate Specificity
2003
Molecular Characterization and Expression of Heparan-sulfate 6-Sulfotransferase
1998
Heparan Sulfate 6-O-Sulfotransferase Is Essential for Muscle Development in Zebrafish
2003
Characterization of Heparan Sulfate Oligosaccharides That Bind to Hepatocyte Growth Factor
1995
β-d -xylosides and their analogues as artificial initiators of glycosaminoglycan chain synthesis. Aglycone-related variation in their effectiveness in vitro and in ovo
1987 StandoutNobel
Expression of heparan sulphate l-iduronyl 2-O-sulphotransferase in human kidney 293 cells results in increased d-glucuronyl 2-O-sulphation
2000
Changes in proteoglycan composition during development of rat skin. The occurrence in fetal skin of a chondroitin sulfate proteoglycan with high turnover rate.
1986
Stem domains of heparan sulfate 6-O-sulfotransferase are required for Golgi localization, oligomer formation and enzyme activity
2004
Substrate specificities of mouse heparan sulphate glucosaminyl 6-O-sulphotransferases
2003
Coordinate regulation of collagen and alkaline phosphatase levels in chick embryo chondrocytes.
1985
Separation and properties of five glycosaminoglycan sulfatases from rat skin.
1979