Citation Impact
Citing Papers
Visualizing enveloping layer glycans during zebrafish early embryogenesis
2010 StandoutNobel
Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila
2006 StandoutNobel
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Impairment of starvation-induced and constitutive autophagy in Atg7 -deficient mice
2005 StandoutNobel
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
Chaperone Suppression of α-Synuclein Toxicity in a Drosophila Model for Parkinson's Disease
2002 StandoutScience
Inhibition of “Tissue” Transglutaminase Increases Cell Survival by Preventing Apoptosis
1999
The DNA-damage response in human biology and disease
2009 StandoutNature
Recent advances in our understanding of neurodegeneration
2009
Apoptosis in the nervous system
2000 StandoutNature
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
2002 StandoutNature
[24] Membrane filter assay for detection of amyloid-like polyglutamine-containing protein aggregates
1999
Firefly luciferase mutants as sensors of proteome stress
2011
Polyglutamine tract expansion of the androgen receptor in a motoneuronal model of spinal and bulbar muscular atrophy
2001
The link between the GBA gene and parkinsonism
2012
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1
1998
Huntington's disease
2007 Standout
Advances in autism genetics: on the threshold of a new neurobiology
2008
Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c
2016 StandoutNobel
Sialic acids in human health and disease
2008
Caspase-8 Is Required for Cell Death Induced by Expanded Polyglutamine Repeats
1999
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
2004 StandoutNature
Nuclear Localization of a Non-caspase Truncation Product of Atrophin-1, with an Expanded Polyglutamine Repeat, Increases Cellular Toxicity
2003
DNA repair mechanisms in dividing and non-dividing cells
2013
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
2010
Tissue transglutaminase: an enzyme with a split personality
1999
Cell Death
2004 Standout
Quality Control of Membraneless Organelles
2018
Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling
2000 StandoutNobel
Polyglutamine-Expanded Human Huntingtin Transgenes Induce Degeneration of Drosophila Photoreceptor Neurons
1998
Clinical and molecular advances in autosomal dominant cerebellar ataxias: from genotype to phenotype and physiopathology
2000
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Endoplasmic reticulum stress: cell life and death decisions
2005 Standout
The Involvement of DNA-Damage and -Repair Defects in Neurological Dysfunction
2008
Decoding ALS: from genes to mechanism
2016 StandoutNature
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
DNA Damage, Aging, and Cancer
2009 Standout
Protein aggregation and neurodegenerative disease
2004 Standout
Protein degradation and protection against misfolded or damaged proteins
2003 StandoutNature
Parkinson's disease
2015 Standout
Protein folding and misfolding
2003 StandoutNature
Transglutaminase potentiates ligand-dependent proteasome dysfunction induced by polyglutamine-expanded androgen receptor
2003
Autophagy in Human Health and Disease
2013 Standout
Dose-ranging study of riluzole in amyotrophic lateral sclerosis
1996 Standout
The epidemiology of ALS: a conspiracy of genes, environment and time
2013
Expanded Polyglutamine Protein Forms Nuclear Inclusions and Causes Neural Degeneration in Drosophila
1998
Basic mechanisms of neurodegeneration: a critical update
2010
Loss of autophagy in the central nervous system causes neurodegeneration in mice
2006 StandoutNature
Defective DNA Repair and Neurodegenerative Disease
2007
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
A Drosophila model of Parkinson's disease
2000 StandoutNature
Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation
2002
SH3GL3 Associates with the Huntingtin Exon 1 Protein and Promotes the Formation of Polygln-Containing Protein Aggregates
1998
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Expanded polyglutamine stretches form an ‘aggresome’
2002
Epidemiology of mutations in superoxide dismutase in amyotrophic lateal sclerosis
1997 StandoutNobel
Single-strand break repair and genetic disease
2008
The epigenetics of aging and neurodegeneration
2015
Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine
2002
Cellular Defenses against Unfolded Proteins
2001
A Neuroligin-4 Missense Mutation Associated with Autism Impairs Neuroligin-4 Folding and Endoplasmic Reticulum Export
2009 StandoutNobel
Risk factors for amyotrophic lateral sclerosis
2015
Protein precipitation: a common etiology in neurodegenerative disorders?
1998
Glucocerebrosidase and Parkinson disease: Recent advances
2015
Parkinson's Disease
2003 Standout
Sequencing technologies — the next generation
2009 Standout
Expression of ataxin-2 in brains from normal individuals and patients with Alzheimer's disease and spinocerebellar ataxia 2
1999
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
2000 StandoutNature
Aggregates in neurodegenerative disease: crowds and power?
1999
The Length of Polyglutamine Tract, Its Level of Expression, the Rate of Degradation, and the Transglutaminase Activity Influence the Formation of Intracellular Aggregates
1999
The Deacetylase HDAC6 Regulates Aggresome Formation and Cell Viability in Response to Misfolded Protein Stress
2003 Standout
Mutant Huntingtin Expression in Clonal Striatal Cells: Dissociation of Inclusion Formation and Neuronal Survival by Caspase Inhibition
1999
EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
2010 Standout
Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease
2000
Therapeutic Effects of Cystamine in a Murine Model of Huntington's Disease
2002
Apoptosis: A Review of Programmed Cell Death
2007 Standout
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
2000
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Glutamine Repeats and Neurodegeneration
2000
KEGG: integrating viruses and cellular organisms
2020 Standout
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
Polyglutamine pathogenesis
1999
Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: Implications for Huntington’s disease pathology
1999
The ubiquitin-proteasome pathway: on protein death and cell life
1998 StandoutNobel
Generation of Neuronal Intranuclear Inclusions by Polyglutamine-GFP: Analysis of Inclusion Clearance and Toxicity as a Function of Polyglutamine Length
1999
DNA Ligases: Structure, Reaction Mechanism, and Function
2006
Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor
1999 StandoutNobel
The Emergence of Modern Neuroscience: Some Implications for Neurology and Psychiatry
2000 StandoutNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Impairment of the Ubiquitin-Proteasome System by Protein Aggregation
2001 StandoutScience
Chemical Glycoproteomics
2016 StandoutNobel
A cellular model that recapitulates major pathogenic steps of Huntington's disease
1998
Mutation of the E6-AP Ubiquitin Ligase Reduces Nuclear Inclusion Frequency While Accelerating Polyglutamine-Induced Pathology in SCA1 Mice
1999 StandoutNobel
Works of Hidetoshi Date being referenced
Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein
2004
Intranuclear Degradation of Polyglutamine Aggregates by the Ubiquitin-Proteasome System
2009
Mutations for Gaucher Disease Confer High Susceptibility to Parkinson Disease
2009
A novel mutation in the GNE gene and a linkage disequilibrium in Japanese pedigrees
2002
Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch
1998
C9ORF72 Repeat Expansion in Amyotrophic Lateral Sclerosis in the Kii Peninsula of Japan
2012
CpG Demethylation Enhances Alpha-Synuclein Expression and Affects the Pathogenesis of Parkinson's Disease
2010
The FHA domain of aprataxin interacts with the C-terminal region of XRCC1
2004
Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3′-phosphate and 3′-phosphoglycolate ends
2007