Citation Impact
Citing Papers
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
2004 StandoutScience
Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
2004 StandoutScience
TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis
2005
A Sulfilimine Bond Identified in Collagen IV
2009 StandoutScienceNobel
Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
2003 StandoutScience
Immunostimulatory CpG-Oligodeoxynucleotides Cause Extramedullary Murine Hemopoiesis
1999
CpG Motifs in Bacterial DNA Activate Leukocytes Through the pH-Dependent Generation of Reactive Oxygen Species
1998
Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9
2008 StandoutNobel
The N-terminal Domain of Drosophila Gram-negative Binding Protein 3 (GNBP3) Defines a Novel Family of Fungal Pattern Recognition Receptors
2009 StandoutNobel
A Toll-like receptor recognizes bacterial DNA
2000 StandoutNature
Innate immune sensing and its roots: the story of endotoxin
2003 StandoutNobel
Fibrosis in Systemic Sclerosis
2008
Type IV collagens regulate BMP signalling in Drosophila
2008 Nature
The sweetness of the DNA backbone drives Toll-like receptor 9
2008
Efficient T Cell Activation via a Toll-Interleukin 1 Receptor-Independent Pathway
2006 StandoutNobel
Development of immunoadjuvants for immunotherapy of cancer
2001
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
2009 StandoutNature
cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
2013 StandoutNature
Advances in vaccine adjuvants
1999
Causing a commotion in the blood: immunotherapy progresses from bacteria to bacterial DNA
2000
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity
2007 StandoutNobel
Antitumor Activity of Synthetic Oligonucleotides with Sequences from cDNA Encoding Proteins of Mycobacterium bovis BCG
1992
A SYNTHETIC SINGLE‐STRANDED DNA, POLY(dG, dC), INDUCES TNTERFERON‐α/β AND ‐γ, AUGMENTS NATURAL KILLER ACTIVITY, AND SUPPRESSES TUMOR GROWTH
1988
Hallmarks of aging: An expanding universe
2023 Standout
Recognition of nucleic acid and nucleic acid analogs by Toll-like receptors 7, 8 and 9
2007
A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA
2005
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Pattern Recognition Receptors and Inflammation
2010 Standout
Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll‐like receptor signaling
2003
The discovery of immunostimulatory DNA sequence
2001
Scleroderma
2009 Standout
Paricalcitol Attenuates Renal Interstitial Fibrosis in Obstructive Nephropathy
2006
Intracellular Toll-like Receptors
2010 StandoutNobel
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Innate immune recognition of, and regulation by, DNA
2006
Exposure to Environmental Microorganisms and Childhood Asthma
2011 Standout
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
Immunostimulatory properties of genomic DNA from different bacterial species
1999
Lymphocyte activation by CpG dinucleotide motifs in prokaryotic DNA
1996
A New Perspective on Therapeutic Inhibition of Advanced Glycation in Diabetic Microvascular Complications: Common Downstream Endpoints Achieved Through Disparate Therapeutic Approaches?
2009
Exploiting dendritic cells to improve vaccine efficacy
2002 StandoutNobel
Immunostimulatory DNA Prepriming: A Novel Approach for Prolonged Th1-Biased Immunity
1999
Intracellular DNA recognition
2010
Direct Immunologic activities of CpG DNA and implications for gene therapy
1999
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
2004
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
2004 StandoutNature
Interactions between bacterial CpG-DNA and TLR9 bridge innate and adaptive immunity
2002
Binding of Oligoguanylate to Scavenger Receptors Is Required for Oligonucleotides to Augment NK Cell Activity and Induce IFN
1994
CpG DNA induces cyclooxygenase-2 expression and prostaglandin production
2001
CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract.
1997
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
2004 Standout
The role of CpG motifs in innate immunity
2000
Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs
2001
Bacterial CpG DNA Activates Immune Cells to Signal Infectious Danger
1999
The influence of base sequence on the immunological properties of defined oligonucleotides
1998
Ability of Oligonucleotides with Certain Palindromes to Induce Interferon Production and Augment Natural Killer Cell Activity Is Associated with Their Base Length
1994
Oligonucleotide Sequences Required for Natural Killer Cell Activation
1992
In vitro Augmentation of Natural Killer Cell Activity and Production of Interferon‐α/β and ‐γ with Deoxyribonucleic Acid Fraction from Mycobacterium bovis BCG
1988
CCR2 antagonism improves insulin resistance, lipid metabolism, and diabetic nephropathy in type 2 diabetic mice
2010
Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells
1999
CpG motifs induce Langerhans cell migration in vivo
2000
Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
2002 StandoutNature
Bacterial DNA as immune cell activator
1998
Candidate rejuvenating factor GDF11 and tissue fibrosis: friend or foe?
2020
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
2008 StandoutNature
Pathogen Recognition and Innate Immunity
2006 Standout
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
2009 StandoutNature
Identification of CpG oligonucleotide sequences with high induction of IFN-α/β in plasmacytoid dendritic cells
2001
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Exploiting dendritic cells to improve vaccine efficacy
2002 StandoutNobel
Toll-Like Receptors
2003 Standout
Naturally Arising CD4+Regulatory T Cells for Immunologic Self -Tolerance and Negative Control of Immune Responses
2003 StandoutNobel
Antimetastatic effect of CpG DNA mediated by type I IFN.
2001
Immunostimulatory DNA Sequences Influence the Course of Adjuvant Arthritis
2002
Mammalian granulocyte–macrophage colony‐stimulating factor and some CpG motifs have an effect on the immunogenicity of DNA and subunit vaccines in fish
1999
Exploiting dendritic cells to improve vaccine efficacy
2002 StandoutNobel
Interleukin-12- and Gamma Interferon-Dependent Protection against Malaria Conferred by CpG Oligodeoxynucleotide in Mice
2001
Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
2009 StandoutNobel
DNA from Bacteria, but Not from Vertebrates, Induces Interferons, Activates Natural Killer Cells and Inhibits Tumor Growth
1992
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
Activation of Natural Killer T Cells by α-Galactosylceramide Rapidly Induces the Full Maturation of Dendritic Cells In Vivo and Thereby Acts as an Adjuvant for Combined CD4 and CD8 T Cell Immunity to a Coadministered Protein
2003 StandoutNobel
CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.
1996 Standout
A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice
2005 StandoutNobel
TYPE I INTERFERONS (α/β) IN IMMUNITY AND AUTOIMMUNITY
2004 StandoutNobel
CpG Motifs in Bacterial DNA and Their Immune Effects
2002 Standout
Synthetic Oligonucleotides with Particular Base Sequences from the cDNA Encoding Proteins of Mycobacterium bovis BCG Induce Interferons and Activate Natural Killer Cells
1992
Extracellular DNA Required for Bacterial Biofilm Formation
2002 StandoutScience
Successful treatment of intracranial gliomas in rat by oligodeoxynucleotides containing CpG motifs.
2000
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
2006 StandoutNobel
Vaccination with Heat-KilledListeriaas Adjuvant Reverses Established Allergen-Induced Airway Hyperreactivity and Inflammation: Role of CD8+ T Cells and IL-18
2000
Vaccination with Plasmid DNA Activates Dendritic Cells via Toll-Like Receptor 9 (TLR9) but Functions in TLR9-Deficient Mice
2003
CpG DNA Induces Sustained IL-12 Expression In Vivo and Resistance to Listeria monocytogenes Challenge
1998
Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization
1996 Science
In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination
2004 StandoutNobel
In vivo augmentation of natural killer cell activity with a deoxyribonucleic acid fraction of BCG.
1986
Mechanisms of Diabetic Complications
2013 Standout
A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease
2003 StandoutNobel
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Now I know my CpGs
2001
Synthetic Oligonucleotides with Certain Palindromes Stimulate Interferon Production of Human Peripheral Blood Lymphocytes in vitro
1994
RIG-I-Mediated Antiviral Responses to Single-Stranded RNA Bearing 5'-Phosphates
2006 StandoutScience
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
2007 StandoutNobel
Lipofection of Synthetic Oligodeoxyribonucleotide Having a Palindromic Sequence of AACGTT to Murine Splenocytes Enhances Interferon Production and Natural Killer Activity
1994
CpG Oligonucleotides Can Prophylactically Immunize Against Th2-Mediated Schistosome Egg-Induced Pathology by an IL-12-Independent Mechanism
2000
Delineation of a CpG Phosphorothioate Oligodeoxynucleotide for Activating Primate Immune Responses In Vitro and In Vivo
2000
CpG-DNA-Mediated Transient Lymphadenopathy Is Associated with a State of Th1 Predisposition to Antigen-Driven Responses
2000
Works of Hideharu Abe being referenced
A Vitamin D Analog Ameliorates Glomerular Injury on Rat Glomerulonephritis
2001
Activation of Bone Morphogenetic Protein 4 Signaling Leads to Glomerulosclerosis That Mimics Diabetic Nephropathy
2011
Inhibition of MCP-1/CCR2 pathway ameliorates the development of diabetic nephropathy
2007
Expression of Smad1 is directly associated with mesangial matrix expansion in rat diabetic nephropathy
2006
Activation of STAT3/Smad1 Is a Key Signaling Pathway for Progression to Glomerulosclerosis in Experimental Glomerulonephritis
2005
Type IV Collagen Is Transcriptionally Regulated by Smad1 under Advanced Glycation End Product (AGE) Stimulation
2004
Antitumor Activity of Deoxyribonucleic Acid Fraction From <italic>Mycobacterium bovis</italic> BCG. I. Isolation, Physicochemical Characterization, and Antitumor Activity<xref ref-type="fn" rid="FN2">2</xref>
1984