Citation Impact
Citing Papers
The P450 Superfamily: Updated Listing of All Genes and Recommended Nomenclature for the Chromosomal Loci
1989
Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach
2012 Standout
Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats
2015 Standout
The prince and the pauper. A tale of anticancer targeted agents
2008
Effect of Leucotrienes C4, D4, Prostacyclin and Thromboxane A2 on isolated human cerebral arteries
1982 StandoutNobel
Responses of human and baboon arteries to prostaglandin endoperoxides and biologically generated and synthetic prostacyclin: their relevance to cerebral arterial spasm in man.
1979
Pharmacology and Management of the Vitamin K Antagonists
2008 Standout
P450 Enzymes
1992
Clinically Important Drug Interactions with Anticoagulants
1996
Effect of mangiferin on hyperglycemia and atherogenicity in streptozotocin diabetic rats
2005 Standout
The genetic polymorphism of debrisoquine/sparteine metabolism — Clinical aspects
1990
Role of AMP-activated protein kinase in mechanism of metformin action
2001 Standout
Simulation and prediction of in vivo drug metabolism in human populations from in vitro data
2007
Impact of genotype on adverse effects during treatment with metoprolol: A prospective clinical study
2005
Chlorpromazine versus placebo for schizophrenia
2007
Vascularized and functional human liver from an iPSC-derived organ bud transplant
2013 StandoutNature
Preparation of human metabolites of propranolol using laboratory‐evolved bacterial cytochromes P450
2005 StandoutNobel
Polymorphism of human cytochrome P450 enzymes and its clinical impact
2009
Dietary Intake and Bioavailability of Polyphenols
2000 Standout
Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology
2020 Standout
Oral Anticoagulant Therapy
2012 Standout
The metabolic syndrome
2010 Standout
Albumin–drug interaction and its clinical implication
2013 Standout
Stereoselective delivery and actions of beta receptor antagonists
1988
Clinical Pharmacokinetics of Metformin
2011
Genetic Polymorphisms of HumanN-Acetyltransferase, Cytochrome P450, Glutathione-S-Transferase, and Epoxide Hydrolase Enzymes: Relevance to Xenobiotic Metabolism and Toxicity
1999
Drug-Induced Hepatotoxicity
2003 Standout
Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient—2013 update: Cosponsored by american association of clinical endocrinologists, The obesity society, and american society for metabolic & bariatric surgery*
2013 Standout
Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study
2000 Standout
The mechanisms of action of metformin
2017 Standout
Prevention of VTE in Nonsurgical Patients
2012 Standout
NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches
2018 Standout
Clinical Pharmacokinetics of Metformin
1996
Once-daily delayed-release metformin lowers plasma glucose and enhances fasting and postprandial GLP-1 and PYY: results from two randomised trials
2016
Pharmacological Management of Diabetes
1999
Bayesian Parameter Estimation and Population Pharmacokinetics
1992
Mortality and Morbidity in Patients Receiving Encainide, Flecainide, or Placebo
1991 Standout
Radioreceptor Assay of Metoprolol in Human Plasma: Comparison with an Enantiospecific High-Performance Liquid Chromatographic (HPLC) Procedure
1989
Single-Dose Intravenous Toxicity Study of IRDye 800CW in Sprague-Dawley Rats
2010
The metabolic syndrome
2005 Standout
The Effect of Intravenous Metformin on Glucose Metabolism During Hyperglycaemia in Type 2 Diabetes
1992
Image-guided cancer surgery using near-infrared fluorescence
2013 Standout
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
2014 StandoutNature
Coumarins: Old Compounds with Novel Promising Therapeutic Perspectives
2010 Standout
Dose-Independent Pharmacokinetics of Metformin in Rats: Hepatic and Gastrointestinal First-Pass Effects
2006
Type 2 diabetes
2017 Standout
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
2013 Nature
Clinical Pharmacokinetics and Pharmacodynamics of Tacrolimus in Solid Organ Transplantation
2004 Standout
Metformin hydrochloride in the treatment of type 2 diabetes mellitus: A clinical review with a focus on dual therapy
2003
Phenotypic polymorphism and gender‐related differences of CYP1A2 activity in a Chinese population
2000
Metformin: An Old Drug for the Treatment of Diabetes but a New Drug for the Protection of the Endothelium
2015
Pharmacokinetics of Oral Antihyperglycaemic Agents in Patients with Renal Insufficiency
1996
Oral Anticoagulants: Mechanism of Action, Clinical Effectiveness, and Optimal Therapeutic Range
2001 Standout
Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry
2004
Polymorphic CYP2D6 mediates O -demethylation of the opioid analgesic tramadol
1997
Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
2012 Standout
Systematic Overview of Warfarin and Its Drug and Food Interactions
2005 Standout
A review on emerging contaminants in wastewaters and the environment: Current knowledge, understudied areas and recommendations for future monitoring
2014 Standout
Clinical Pharmacology of Tramadol
2004 Standout
Appropriate Phenotyping Procedures for Drug Metabolizing Enzymes and Transporters in Humans and Their Simultaneous Use in the “Cocktail” Approach
2007
Involvement of Organic Cation Transporter 1 in Hepatic and Intestinal Distribution of Metformin
2002
Polymorphic Cytochrome P450 2D6: Humanized Mouse Model and Endogenous Substrates
2004
Metformin and the gastrointestinal tract
2016
Influence of hydroxychloroquine on the bioavailability of oral metoprolol
2000
Herb-Drug Interactions
2005 Standout
The Pharmacology and Management of the Vitamin K Antagonists
2004 Standout
Methadone inhibits CYP2D6 and UGT2B7/2B4in vivo: a study using codeine in methadone‐ and buprenorphine‐maintained subjects
2011
IN VITRO EFFECTS OF ANTIPSYCHOTICS ON HUMAN PLATELET ADHESION AND AGGREGATION AND PLASMA COAGULATION
2007 StandoutNobel
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
Venous Thromboembolism Among Elderly Patients Treated With Atypical and Conventional Antipsychotic Agents
2005
Accumulation of metformin by tissues of the normal and diabetic mouse
1994
Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis
2013 Standout
Impact of the CYP2D6 Genotype on the Clinical Effects of Metoprolol: A Prospective Longitudinal Study
2008
Indolizidine and quinolizidine alkaloids
2004 Standout
The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature
1993 Standout
Faster absorption of ethanol and higher peak concentration in women after gastric bypass surgery
2002
Tryptamine Receptors in the Central Nervous System
1961 StandoutNatureNobel
Chlorpromazine versus placebo for schizophrenia
2014
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Management of Hyperglycemia in Type 2 Diabetes, 2015: A Patient-Centered Approach: Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes
2014 Standout
Clinical significance of the sparteine/debrisoquine oxidation polymorphism
1989
Effect of Gastric Bypass Surgery on the Absorption and Bioavailability of Metformin
2011
Variations in Drug Metabolism Due to Genetic Polymorphism
1993
The Primary Glucose-Lowering Effect of Metformin Resides in the Gut, Not the Circulation: Results From Short-term Pharmacokinetic and 12-Week Dose-Ranging Studies
2015
Guidelines for the Primary Prevention of Stroke
2014 Standout
Special Issue: KDIGO Clinical Practice Guideline for the Care of Kidney Transplant Recipients
2009 Standout
Pharmacologic causes of arrhythmogenic actions of antiarrhythmic drugs
1987
Subcellular distribution of metformin in rat liver
1991
Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers—N‐desisopropylation is mediated mainly by CYP1A2.
1995
The effect of enzyme inhibition on the metabolism and activation of tacrine by human liver microsomes.
1994
Antipsychotic-Induced Venous Thromboembolism
2002
Repurposing metformin: an old drug with new tricks in its binding pockets
2015
Acute Toxicity of Ropivacaine Compared with That of Bupivacaine
1989 Standout
Pharmacogenetic testing among patients with mood and anxiety disorders is associated with decreased utilization and cost: A propensity-score matched study
2018 StandoutNobel
Prediction of metabolic drug interactions involving beta‐adrenoceptor blocking drugs.
1984
Metoprolol-paroxetine interaction in human liver microsomes: stereoselective aspects and prediction of the in vivo interaction.
2001
Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods
2019 Standout
Occurrence of drugs in German sewage treatment plants and rivers
1998 Standout
PHARAMACOKINETICS OF LOCAL ANAESTHETICS
1986
Interactions of Warfarin with Drugs and Food
1994
Heme-Containing Oxygenases
1996 Standout
Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics
1999 StandoutScience
Use of Metformin in the Setting of Mild-to-Moderate Renal Insufficiency
2011
Importance of amine pKa and distribution coefficient in the metabolism of fluorinated propranolol derivatives. Preparation, identification of metabolite regioisomers, and metabolism by CYP2D6.
2001
The effects of neuroleptic drugs on 5‐hydroxytryptamine induced platelet aggregation in schizophrenic patients.
1981
Industry sponsorship and research outcome
2017 Standout
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
2000 Standout
Works of HF Woods being referenced
The effect of beta‐adrenoceptor antagonists on the pharmacokinetics and pharmacodynamics of warfarin after a single dose.
1984
Polymorphic drug oxidation: pharmacokinetic basis and comparison of experimental indices.
1986
Effects of beta‐adrenoceptor antagonists on the pharmacokinetics of lignocaine.
1984
Lack of effect of atenolol on antipyrine clearance.
1982
Propranolol oxidation by human liver microsomes‐the use of cumene hydroperoxide to probe isoenzyme specificity and regio‐ and stereoselectivity.
1990
Determination of metformin in biological samples.
1978
Polymorphic metabolism of beta‐adrenoceptor antagonists.
1984
Metformin kinetics in healthy subjects and in patients with diabetes mellitus.
1981
Testing for bimodality in frequency distributions of data suggesting polymorphisms of drug metabolism‐histograms and probit plots.
1989
Testing for bimodality in frequency distributions of data suggesting polymorphisms of drug metabolism‐hypothesis testing.
1989
The impairment of lignocaine clearance by propranolol‐major contribution from enzyme inhibition.
1985
Metoprolol metabolism and debrisoquine oxidation polymorphism‐ population and family studies.
1985
The effect of beta‐adrenoceptor antagonists on the pharmacokinetics and pharmacodynamics of warfarin.
1984
Lignocaine and indocyanine green kinetics in patients following myocardial infarction.
1980
Increased platelet aggregation responses to 5‐hydroxytryptamine in patients taking chlorpromazine.
1975
The relationship between debrisoquine oxidation phenotype and the pharmacokinetics and pharmacodynamics of propranolol.
1984
Backtracking booze with Bayes‐the retrospective interpretation of blood alcohol data.
1991
Stereoselective metabolism of metoprolol in Caucasians and Nigerians‐ relationship to debrisoquine oxidation phenotype.
1989
Timolol and atenolol: relationships between oxidation phenotype, pharmacokinetics and pharmacodynamics.
1985