Citation Impact
Citing Papers
Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules
2006
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Zebrafish MiR-430 Promotes Deadenylation and Clearance of Maternal mRNAs
2006 Science
Inhibition of Translational Initiation by Let-7 MicroRNA in Human Cells
2005 Science
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
2012 StandoutScienceNobel
The use of mRNA display to select high-affinity protein-binding peptides
2001 StandoutNobel
MicroRNAs direct rapid deadenylation of mRNA
2006
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
β-Arrestin-mediated Signaling Regulates Protein Synthesis
2008 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses
2017
Brawn for Brains: The Role of MEF2 Proteins in the Developing Nervous System
2005
Role of p38α Map Kinase in Type I Interferon Signaling
2004
HuR recruits let-7/RISC to repress c-Myc expression
2009
Mechanisms of type-I- and type-II-interferon-mediated signalling
2005 Standout
Small binding proteins selected from a combinatorial repertoire of knottins displayed on phage
1998 StandoutNobel
Sorting of Drosophila Small Silencing RNAs
2007
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Improvements to the Kunkel mutagenesis protocol for constructing primary and secondary phage-display libraries
2012
Oxidative stress and gene regulation
2000
Acquisition of Sensitivity of Stress-activated Protein Kinases to the p38 Inhibitor, SB 203580, by Alteration of One or More Amino Acids within the ATP Binding Pocket
1998
Phage Display Technology in Antibody Engineering: Design of Phagemid Vectors and in vitro Maturation Systems
1992
Post-translational control of the MEF2A transcriptional regulatory protein
1999
p38 Mitogen-activated Protein Kinase Pathway Protects Adult Rat Ventricular Myocytes against β-Adrenergic Receptor-stimulated Apoptosis
2000
Suppression of human Mnk1 by small interfering RNA increases the eukaryotic initiation factor 4F activity in HEK293T cells
2004
nhl-2 Modulates MicroRNA Activity in Caenorhabditis elegans
2009 StandoutNobel
Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs
2008
The role of the AU-rich elements of mRNAs in controlling translation
2004
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
2011 Standout
A microRNA Mediates EGF Receptor Signaling and Promotes Photoreceptor Differentiation in the Drosophila Eye
2005
The p38 MAPK Pathway Mediates the Growth Inhibitory Effects of Interferon-α in BCR-ABL-expressing Cells
2001
Sequential Activation of Signaling Pathways during Innate Immune Responses in Drosophila
2002
Highly Efficient Green Fluorescent Protein-Based Kinase Substrates
1999
β2-Adrenergic Receptor-induced p38 MAPK Activation Is Mediated by Protein Kinase A Rather than by Gi or Gβγ in Adult Mouse Cardiomyocytes
2000 StandoutNobel
Building a Replisome from Interacting Pieces
1999 StandoutNobel
Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells
2009
Identification of biologically active peptides using random libraries displayed on phage
1995
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
Preferential Binding of Grb2 or Phosphatidylinositol 3-Kinase to the Met Receptor Has Opposite Effects on HGF-Induced Myoblast Proliferation
2002
A MyoD-generated feed-forward circuit temporally patterns gene expression during skeletal muscle differentiation
2004
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
The Biologic Significance of Human Natural Autoimmune Responses: Relationship to the Germline, Early Immune and Malignant B Cell Variable Gene Repertoire
1990
Does phosphorylation of the cap‐binding protein eIF4E play a role in translation initiation?
2002
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
MEF2: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation
1999
Regulation by let-7 and lin-4 miRNAs Results in Target mRNA Degradation
2005
Activation of the p38 Mitogen-activated Protein Kinase Mediates the Suppressive Effects of Type I Interferons and Transforming Growth Factor-β on Normal Hematopoiesis
2002
Selection of human anti-hapten antibodies from semisynthetic libraries
1993
Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies
2005
Tools for Coproducing Multiple Proteins in Mammalian Cells
2011
Distinct carboxy‐termini confer divergent characteristics to the mitogen‐activated protein kinase p38α and its splice isoform Mxi2
2000
Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties
2006
Argonaute proteins: key players in RNA silencing
2007
MEK Kinase 3 Directly Activates MKK6 and MKK7, Specific Activators of the p38 and c-Jun NH2-terminal Kinases
1999
Caspase Functions in Cell Death and Disease
2013 Standout
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
2005
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3(Mkk3)-deficient mice
1999
AU-Rich-Element-Mediated Upregulation of Translation by FXR1 and Argonaute 2
2007
Regulation of Skeletal Myogenesis by Association of the MEF2 Transcription Factor with Class II Histone Deacetylases
2000
MyoD and the transcriptional control of myogenesis
2005
The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions
2008 StandoutNobel
PRAK, a novel protein kinase regulated by the p38 MAP kinase
1998
Function and Localization of MicroRNAs in Mammalian Cells
2006
The immune response of Drosophila
2003 StandoutNatureNobel
The p38 mitogen-activated protein kinase pathway and its role in interferon signaling
2003
Human Antibodies with Sub-nanomolar Affinities Isolated from a Large Non-immunized Phage Display Library
1996
A Large Non-immunized Human Fab Fragment Phage Library That Permits Rapid Isolation and Kinetic Analysis of High Affinity Antibodies
1999
MAP kinase pathways
1999
The drosophila gastrulation gene concertina encodes a Gα-like protein
1991 StandoutNobel
Building Antibodies from their Genes
1992 StandoutNobel
Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution
1998
The microRNA-argonaute complex: A platform for mRNA modulation
2008
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
GW Bodies, MicroRNAs and the Cell Cycle
2006
mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes
2006
Phosphorylation Motifs Regulating the Stability and Function of Myocyte Enhancer Factor 2A
2003
Molecular determinants that mediate selective activation of p38 MAP kinase isoforms
2000
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression
2007 StandoutNobel
p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation
2007
The repertoire of human germline vH sequences reveals about fifty groups of VH segments with different hypervariable loops
1992 StandoutNobel
The Developmental Timing Regulator AIN-1 Interacts with miRISCs and May Target the Argonaute Protein ALG-1 to Cytoplasmic P Bodies in C. elegans
2005
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Crystal Structure of an Ephrin Ectodomain
2001
New Insights into the Control of MAP Kinase Pathways
1999
Regulation of muscle regulatory factors by DNA-binding, interacting proteins, and post-transcriptional modifications
2000
MAPK-regulated transcription: a continuously variable gene switch?
2002
Promoter-Specific Regulation of MyoD Binding and Signal Transduction Cooperate to Pattern Gene Expression
2002
The Evolution of the MAP Kinase Pathways: Coduplication of Interacting Proteins Leads to New Signaling Cascades
1999
In vitro selection from protein and peptide libraries
1994
Phosphorylation of Eukaryotic Initiation Factor 4E Markedly Reduces Its Affinity for Capped mRNA
2002
From Human Autoantibodies to the Fetal Antibody Repertoire to B Cell Malignancy: It's a Small World After All
1990
Phosphorylation of MAP Kinases by MAP/ERK Involves Multiple Regions of MAP Kinases
1999
Restricted diversity of the variable region nucleotide sequences of the heavy and light chains of a human rheumatoid factor
1991
Cancer-related inflammation
2008 StandoutNature
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Most Caenorhabditis elegans microRNAs Are Individually Not Essential for Development or Viability
2007 StandoutNobel
p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci
2004
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Argonaute Proteins: Mediators of RNA Silencing
2007
Manufacturing Immunity to Disease in a Test Tube: The Magic Bullet Realized
2006
Control of translation and mRNA degradation by miRNAs and siRNAs: Table 1.
2006 Standout
Inference of miRNA targets using evolutionary conservation and pathway analysis
2007
P bodies: at the crossroads of post-transcriptional pathways
2006
Dual modulation of cell survival and cell death by β 2 -adrenergic signaling in adult mouse cardiac myocytes
2001 StandoutNobel
Axonal Ephrin-As and Odorant Receptors
2003 StandoutNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
RNA-peptide fusions for the in vitro selection of peptides and proteins
1997 StandoutNobel
MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function
2005
Molecular characterization of five human anti-human immunodeficiency virus type 1 antibody heavy chains reveals extensive somatic mutation typical of an antigen-driven immune response.
1991
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Adenylyl Cyclase Amino Acid Sequence: Possible Channel- or Transporter-Like Structure
1989 StandoutScienceNobel
Primary structure of T4 DNA polymerase. Evolutionary relatedness to eucaryotic and other procaryotic DNA polymerases.
1988
p38 and Extracellular Signal-Regulated Kinases Regulate the Myogenic Program at Multiple Steps
2000
IL-17 Family Cytokines and the Expanding Diversity of Effector T Cell Lineages
2007 Standout
Sweeping antibody as a novel therapeutic antibody modality capable of eliminating soluble antigens from circulation
2016
Rolling replication of short DNA circles.
1995 StandoutNobel
Efficient method for construction comprehensive murine Fab antibody libraries displayed on phage
1993
Mnk1 Is Required for Angiotensin II–Induced Protein Synthesis in Vascular Smooth Muscle Cells
2003
Cytoplasmic Signaling Pathways That Regulate Cardiac Hypertrophy
2001
Making Antibodies by Phage Display Technology
1994 StandoutNobel
Targeting of p38 Mitogen-Activated Protein Kinases to MEF2 Transcription Factors
1999
Divergence of a DNA Replication Gene Cluster in the T4-Related Bacteriophage RB69
1998
Cell-type-specific signatures of microRNAs on target mRNA expression
2006
Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases
2002 StandoutScience
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression
1999
"Diabodies": small bivalent and bispecific antibody fragments.
1993 StandoutNobel
Akt2, a Novel Functional Link between p38 Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Pathways in Myogenesis
2004
p38-γ–dependent gene silencing restricts entry into the myogenic differentiation program
2009
How Do MicroRNAs Regulate Gene Expression?
2007
Deficiency of the Stress Kinase P38α Results in Embryonic Lethality
2000
Phage Display
1997
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 Standout
Tumor Necrosis Factor-α Stimulates the Epithelial-to-Mesenchymal Transition of Human Colonic Organoids
2003
STRUCTURAL AND MECHANISTIC DETERMINANTS OF AFFINITY AND SPECIFICITY OF LIGANDS DISCOVERED OR ENGINEERED BY PHAGE DISPLAY
1997
Human rheumatoid B-1a (CD5+ B) cells make somatically hypermutated high affinity IgM rheumatoid factors.
1993
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
2011 StandoutScienceNobel
Satellite Cells and the Muscle Stem Cell Niche
2013 Standout
Mnk2 and Mnk1 Are Essential for Constitutive and Inducible Phosphorylation of Eukaryotic Initiation Factor 4E but Not for Cell Growth or Development
2004
Macrophages Induce Invasiveness of Epithelial Cancer Cells Via NF-κB and JNK
2005
Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity
2000 Standout
Map kinase signaling pathways and hematologic malignancies
2003
Structural Basis for Double-Stranded RNA Processing by Dicer
2006 StandoutScienceNobel
Regulation of mRNA Translation and Stability by microRNAs
2010 Standout
A Network of Mitogen-Activated Protein Kinases Links G Protein-Coupled Receptors to the c-jun Promoter: a Role for c-Jun NH2-Terminal Kinase, p38s, and Extracellular Signal-Regulated Kinase 5
1999
The neuronal microRNA system
2006
microRNA Functions
2007 Standout
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Regulation of protein synthesis by eIF4E phosphorylation in adult cardiocytes: the consequence of secondary structure in the 5′-untranslated region of mRNA
2004
Human anti-self antibodies with high specificity from phage display libraries.
1993
Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system.
1992 StandoutNobel
Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces
2015 StandoutScienceNobel
Sigma factors fromE. coli, B. subtilis, phage SP01, and phage T4 are homologous proteins
1986
Works of Hermann Gram being referenced
MNK1 and MNK2 Regulation in HER2-overexpressing Breast Cancer Lines
2006
Secretion of scFv Antibody Fragments
1998
Binding Epitope of Somatostatin Defined by Phage-Displayed Peptide Libraries
1995
Complete protein sequences of the variable regions of the cloned heavy and light chains of a human anti-cytomegalovirus antibody reveal a striking similarity to human monoclonal rheumatoid factors of the Wa idiotypic family.
1988
A randomized controlled trial with an anti‐CCL2 (anti–monocyte chemotactic protein 1) monoclonal antibody in patients with rheumatoid arthritis
2006
Blocking of Interleukin-17 during Reactivation of Experimental Arthritis Prevents Joint Inflammation and Bone Erosion by Decreasing RANKL and Interleukin-1
2005
The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis
2008
Characterization of the Structure and Function of the Fourth Member of p38 Group Mitogen-activated Protein Kinases, p38δ
1997
Involvement of MicroRNA in AU-Rich Element-Mediated mRNA Instability
2005
Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced obesity
2008
Catalytic Specificity of Phosphotyrosine Kinases Blk, Lyn, c-Src and Syk as Assessed by Phage Display
1996
Phage display as a rapid gene expression system: production of bioactive cytokine-phage and generation of neutralizing monoclonal antibodies
1993
Phosphorylation of eIF-4E on Ser 209 in Response to Mitogenic and Inflammatory Stimuli Is Faithfully Detected by Specific Antibodies
2000
Eukaryotic Expression Systems: A Comparison
1996
In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library.
1992
Genes 55, alpha gt, 47 and 46 of bacteriophage T4: the genomic organization as deduced by sequence analysis.
1985
Negative Regulation of Protein Translation by Mitogen-Activated Protein Kinase-Interacting Kinases 1 and 2
2001
A physical map of bacteriophage T4 including the positions of strong promoters and terminators recognized in vitro
1984
Regulation of the MEF2 Family of Transcription Factors by p38
1999
MAPKK-Independent Activation of p38α Mediated by TAB1-Dependent Autophosphorylation of p38α
2002 Science
Regulation of TNF Expression by Multiple Mitogen-Activated Protein Kinase Pathways
2000