Citation Impact
Citing Papers
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Voltage sensor conformations in the open and closed states in rosetta structural models of K + channels
2006 StandoutNobel
SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open
2012 StandoutScienceNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130
2002 StandoutNobel
Oligomerization of the integrin αIIbβ3: Roles of the transmembrane and cytoplasmic domains
2001
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
The Single Transmembrane Domains of ErbB Receptors Self-associate in Cell Membranes
2002
Nicastrin Functions as a γ-Secretase-Substrate Receptor
2005 StandoutNobel
The GxxxG motif: A framework for transmembrane helix-helix association
2000
Electron Transfer from the Tetraheme Cytochrome to the Special Pair in the Rhodopseudomonas viridis Reaction Center: Effect of Mutations of Tyrosine L162
1995 Nobel
Natural engineering principles of electron tunnelling in biological oxidation–reduction
1999 StandoutNature
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
The biology and management of non-small cell lung cancer
2018 StandoutNature
Proline-induced Distortions of Transmembrane Helices
2002
A Peptide Derived from a β2-Adrenergic Receptor Transmembrane Domain Inhibits Both Receptor Dimerization and Activation
1996
Eph receptor signalling casts a wide net on cell behaviour
2005
The dynamic disulphide relay of quiescin sulphydryl oxidase
2012 StandoutNatureNobel
The dimerization motif of the glycophorin A transmembrane segment in membranes: Importance of glycine residues
1998
Structural determinants of water permeation through aquaporin-1
2000 StandoutNatureNobel
Electrostatic interactions between transmembrane segments mediate folding of Shaker K+ channel subunits
1997
Four helix bundle diversity in globular proteins
1994
Sodium-Dependent Neurotransmitter TRANSPORTERS: OLIGOMERIZATION as a Determinant of Transporter Function and Trafficking
2004
Determinants for Membrane Association of the Hepatitis C Virus RNA-dependent RNA Polymerase
2001 StandoutNobel
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters
2005 StandoutNature
Mechanisms of Integral Membrane Protein Insertion and Folding
2014
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Immunity, Inflammation, and Cancer
2010 Standout
The Erythropoietin Receptor Transmembrane Domain Mediates Complex Formation with Viral Anemic and Polycythemic gp55 Proteins
2003
Molecular Cloning and Characterization of Mammalian Homologues of Vesicle-Associated Membrane Protein-Associated (VAMP-Associated) Proteins
1999
Influence of Interleukin-6 (IL-6) Dimerization on Formation of the High Affinity Hexameric IL-6·Receptor Complex
1996
Rational design of `water-soluble' bacteriorhodopsin variants
2002 StandoutNobel
Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with β-branched residues at neighboring positions
2000
Protein engineering methods applied to membrane protein targets
2012
Deceiving appearances: signaling by “dead” and “fractured” receptor protein-tyrosine kinases
2000
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
The Membrane- and Soluble-Protein Helix-Helix Interactome: Similar Geometry via Different Interactions
2015
Folding of β-sheets in membranes: specificity and promiscuity in peptide model systems
2001
Properties of integral membrane protein structures: Derivation of an implicit membrane potential
2005
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
Effective coupling in biological electron transfer: exponential or complex distance dependence?
1993 Science
Eph receptors and ephrins in cancer: bidirectional signalling and beyond
2010
A Conserved GXXXG Motif in APH-1 Is Critical for Assembly and Activity of the γ-Secretase Complex
2004
Transmembrane Structure of an Inwardly Rectifying Potassium Channel
1999
Interhelical hydrogen bonding drives strong interactions in membrane proteins.
2000
Integrins
2002 Standout
Structural clues in the sequences of the aquaporins
2000
The role of IL-6 and STAT3 in inflammation and cancer
2005 Standout
Angiogenesis as a therapeutic target
2005 StandoutNature
The EGFR Family: Not So Prototypical Receptor Tyrosine Kinases
2014
A Heptad Motif of Leucine Residues Found in Membrane Proteins Can Drive Self-assembly of Artificial Transmembrane Segments
1999
Crystal structure of photosystem II from Synechococcus elongatus at 3.8 Å resolution
2001 StandoutNature
Toward high-resolution prediction and design of transmembrane helical protein structures
2007 StandoutNobel
Helix-packing motifs in membrane proteins
2006
A Transmembrane Helix Dimer: Structure and Implications
1997 Science
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Reconstitution and functional comparison of purified GlpF and AqpZ, the glycerol and water channels from Escherichia coli
2001 StandoutNobel
JAK2 activation by growth hormone and other cytokines
2015
Electrostatics and dynamics of proteins
2003
Lipid–protein interactions in DHPC micelles containing the integral membrane protein OmpX investigated by NMR spectroscopy
2002 StandoutNobel
The Protein Kinase Complement of the Human Genome
2002 StandoutScience
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
Proposed three-dimensional structure for the cellular prion protein.
1994 StandoutNobel
MEMBRANE PROTEIN FOLDING AND STABILITY: Physical Principles
1999
Probing the SecYEG translocation pore size with preproteins conjugated with sizable rigid spherical molecules
2011 StandoutNobel
Calculation of free-energy differences from computer simulations of initial and final states
1996
Computer Simulation of the Chemical Catalysis of DNA Polymerases: Discriminating between Alternative Nucleotide Insertion Mechanisms for T7 DNA Polymerase
2003 StandoutNobel
Self-Assembly of CdSe−ZnS Quantum Dot Bioconjugates Using an Engineered Recombinant Protein
2000 StandoutNobel
COMPUTER SIMULATIONS WITH EXPLICIT SOLVENT: Recent Progress in the Thermodynamic Decomposition of Free Energies and in Modeling Electrostatic Effects
1998
Identification and Characterization of Disulfide Bonds in Proteins and Peptides from Tandem MS Data by Use of the MassMatrix MS/MS Search Engine
2007
Tandem Facial Amphiphiles for Membrane Protein Stabilization
2010 StandoutNobel
The third helix of the Antennapedia homeodomain translocates through biological membranes.
1994 Standout
Mouse VAP33 is associated with the endoplasmic reticulum and microtubules
2000 StandoutNobel
PrlA suppressor mutations cluster in regions corresponding to three distinct topological domains.
1993
Transmembrane-domain determinants for SNARE-mediated membrane fusion
2010
Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport
2017
A Model for the Photosystem II Reaction Center Core Including the Structure of the Primary Donor P680,
1996
Prediction of membrane protein structures with complex topologies using limited constraints
2009 StandoutNobel
Energetics and Kinetics of Primary Charge Separation in Bacterial Photosynthesis
2008
Quantum Mechanical Continuum Solvation Models
2005 Standout
How important are entropic contributions to enzyme catalysis?
2000 StandoutNobel
Determining complete electron flow in the cofactor photoreduction of oxidized photolyase
2013 StandoutNobel
Experimental Evidence for Intramolecular Blue-Shifting C−H···O Hydrogen Bonding by Matrix-Isolation Infrared Spectroscopy
2003 StandoutNobel
Frozen Density Functional Free Energy Simulations of Redox Proteins: Computational Studies of the Reduction Potential of Plastocyanin and Rusticyanin
2003 StandoutNobel
On the energetics of translocon-assisted insertion of charged transmembrane helices into membranes
2010 StandoutNobel
Femtosecond dynamics of DNA-mediated electron transfer
1999 StandoutNobel
Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins
2017 StandoutNobel
The Cα—H⋅⋅⋅O hydrogen bond: A determinant of stability and specificity in transmembrane helix interactions
2001
Works of Herbert Treutlein being referenced
Sequence specificity in the dimerization of transmembrane .alpha.-helixes
1992
Dissecting the EphA3/Ephrin-A5 Interactions Using a Novel Functional Mutagenesis Screen
2004
A dimerization motif for transmembrane α–helices
1994
Structure‐Function analysis of human IL‐6: Identification of two distinct regions that are important for receptor binding
1994
Disulfide Bond Structure and N-Glycosylation Sites of the Extracellular Domain of the Human Interleukin-6 Receptor
1999
The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor
2005
Chromophore-protein interactions and the function of the photosynthetic reaction center: a molecular dynamics study.
1992 Nobel