Citation Impact
Citing Papers
Structural Basis of Transcription Initiation
2012 Science
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription
2010 StandoutNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Epothilones – A fascinating family of microtubule stabilizing antitumor agents
2008
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Inhibitors of NADH–ubiquinone reductase: an overview
1998
Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
2006 StandoutNobel
Analysis of the Ambruticin and Jerangolid Gene Clusters of Sorangium cellulosum Reveals Unusual Mechanisms of Polyketide Biosynthesis
2006
Incorporation of Nonmethyl Branches by Isoprenoid-like Logic: Multiple β-Alkylation Events in the Biosynthesis of Myxovirescin A1
2007
Biosynthesis of Volatiles by the Myxobacterium Myxococcus xanthus
2004
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
Dynamic Covalent Chemistry
2002 StandoutNobel
A Type II Polyketide Synthase from the Gram‐Negative Bacterium Stigmatella aurantiaca Is Involved in Aurachin Alkaloid Biosynthesis
2007
Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum
2000
The remarkable metal-catalysed olefin metathesis reaction
2007 StandoutNature
Imaging in the era of molecular oncology
2008 StandoutNature
Tubulysins, New Cytostatic Peptides from Myxobacteria Acting on Microtubuli. Production, Isolation, Physico-chemical and Biological Properties.
2000
Identification and analysis of the chivosazol biosynthetic gene cluster from the myxobacterial model strain Sorangium cellulosum So ce56
2005
Isolation, Crystal and Solution Structure Determination, and Biosynthesis of Tubulysins—Powerful Inhibitors of Tubulin Polymerization from Myxobacteria
2004
DNA sequence selectivities in the covalent bonding of antibiotic saframycins Mx1, Mx3, A, and S deduced from MPE.cntdot.iron(II) footprinting and exonuclease III stop assays
1992
Structural visualization of key steps in human transcription initiation
2013 Nature
Multimodal Measurements of Single-Molecule Dynamics Using FluoRBT
2017
Characterization of biosynthetic gene cluster for the production of virginiamycin M, a streptogramin type A antibiotic, in Streptomyces virginiae
2007
Biosynthesis of polyketides (other than actinomycete macrolides)
1999
De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells
2014
Natural‐Product Sugar Biosynthesis and Enzymatic Glycodiversification
2008
Synthesis ofα,β-Unsaturated Amides by Olefin Cross-Metathesis
2001 StandoutNobel
Molecular Insights into the Biosynthesis of Guadinomine: A Type III Secretion System Inhibitor
2012 StandoutNobel
Molybdenum and Tungsten Imido Alkylidene Complexes as Efficient Olefin‐Metathesis Catalysts
2003 StandoutNobel
Protein‐Reactive Natural Products
2005
Genetically programmed chiral organoborane synthesis
2017 StandoutNatureNobel
Protein–Protein Interactions in Multienzyme Megasynthetases
2008
Biosynthesis of oxygen and nitrogen-containing heterocycles in polyketides
2016
A New Highly Efficient Ruthenium Metathesis Catalyst This work was supported by the Fonds der Chemischen Industrie.
2002
Characterization of the Mupirocin Biosynthesis Gene Cluster from Pseudomonas fluorescens NCIMB 10586
2003
Inhibition of Bacterial RNA Polymerase by Streptolydigin: Stabilization of a Straight-Bridge-Helix Active-Center Conformation
2005
Lipoprotein Signal Peptidase Inhibitors with Antibiotic Properties Identified through Design of a Robust In Vitro HT Platform
2018
DKxanthene Biosynthesis—Understanding the Basis for Diversity-Oriented Synthesis in Myxobacterial Secondary Metabolism
2008
Chivosazole A—Elucidation of the Absolute and Relative Configuration
2007
Mutasynthesis‐Derived Myxalamids and Origin of the Isobutyryl‐CoA Starter Unit of Myxalamid B
2007
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble
2015 Nobel
New Lessons for Combinatorial Biosynthesis from Myxobacteria
1999
Myxovirescin A Biosynthesis is Directed by Hybrid Polyketide Synthases/Nonribosomal Peptide Synthetase, 3‐Hydroxy‐3‐Methylglutaryl–CoA Synthases, and trans‐Acting Acyltransferases
2006
New methods for stereochemical determination of complex polyketides: configurational assignment of novel metabolites from myxobacteria
2008
Spiroketal Polyketide Formation in Sorangium: Identification and Analysis of the Biosynthetic Gene Cluster for the Highly Cytotoxic Spirangienes
2007
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
A movie of the RNA polymerase nucleotide addition cycle
2009
Die Olefinmetathese in der organischen Synthese
1997
Total Synthesis of (−)-Ratjadone
2001
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Sets of Aldolase Antibodies with Antipodal Reactivities. Formal Synthesis of Epothilone E by Large-Scale Antibody-Catalyzed Resolution of Thiazole Aldol
1999
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Olefin Metathesis in Organic Chemistry
1997
Natural Product Synthesis Using Multicomponent Reaction Strategies
2009 Standout
Stereoelectronic Effects Characterizing Nucleophilic Carbene Ligands Bound to the Cp*RuCl (Cp* = η5-C5Me5) Moiety: A Structural and Thermochemical Investigation
1999
A General Model for Selectivity in Olefin Cross Metathesis
2003 StandoutNobel
Directed Evolution: Bringing New Chemistry to Life
2017 StandoutNobel
Total Syntheses of Epothilones A and B
1997
Mechanism and Activity of Ruthenium Olefin Metathesis Catalysts
2001 StandoutNobel
Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins
2014
Catalytic iron-carbene intermediate revealed in a cytochrome c carbene transferase
2018 StandoutNobel
Total Synthesis of Oxacyclic Macrodiolide Natural Products
2005
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
Synthesis of saframycins. V. Selenium oxide oxidation of hexahydro-1,5-imino-3-benzazocin-7,10-dione; a useful method for constructing saframycins C and D from saframycin B
1990
Highly Stereo- and Regioselective Synthesis of (Z)-Trisubstituted Alkenes via 1-Bromo-1-alkyne Hydroboration−Migratory Insertion−Zn-Promoted Iodinolysis and Pd-Catalyzed Organozinc Cross-Coupling
2007 StandoutNobel
Aurachin‐Biosynthese im Gram‐negativen Bakterium Stigmatella aurantiaca: Beteiligung einer Typ‐II‐Polyketidsynthase
2007
An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria
2000 StandoutNobel
Development and Applications of Disulfonimides in Enantioselective Organocatalysis
2015 StandoutNobel
Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
2021 StandoutNobel
Total Synthesis of (−)-Callystatin A
2001
Chemistry and Biology of the Tetrahydroisoquinoline Antitumor Antibiotics
2002 Standout
Ribosomal Synthesis of Dehydroalanine-Containing Peptides
2006 StandoutNobel
Synthesis of saframycins. XII. 1 total synthesis of (-)-N-acetylsaframycin Mx 2 and Its epi-(+)-enantiomer
1995
The antibody catalysis route to the total synthesis of epothilones
1998
Diketopiperazines as Advanced Intermediates in the Biosynthesis of Ecteinascidins
2000
Proline-Catalyzed Direct Asymmetric Aldol Reactions
2000 StandoutNobel
Confined acids catalyze asymmetric single aldolizations of acetaldehyde enolates
2018 StandoutScienceNobel
Structural Perspective on Mutations Affecting the Function of Multisubunit RNA Polymerases
2006
On the History of Hepatitis C Virus Cell Culture Systems
2013
Lewis-acid catalyzed formation of dihydropyrans
2011
A New Antitumor Isoquinoline Alkaloid from the Marine Nudibranch Jorunna funebris
2000
Structural basis of transcription inhibition by α-amanitin and implications for RNA polymerase II translocation
2008
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Synthesis, Structure, and Activity of Enhanced Initiators for Olefin Metathesis
2003 StandoutNobel
Spirangien A and B, Highly Cytotoxic and Antifungal Spiroketals from the Myxobacterium Sorangium cellulosum: Isolation, Structure Elucidation and Chemical Modifications
2005
IDPi Catalysis
2019 StandoutNobel
Examining the Role of Hydrogen Bonding Interactions in the Substrate Specificity for the Loading Step of Polyketide Synthase Thioesterase Domains
2008
Synthesis of saframycins. XI. Synthetic studies toward a total synthesis of safracin A
1995
Asymmetric Catalysis via Cyclic, Aliphatic Oxocarbenium Ions
2017 StandoutNobel
Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450 BM3 demethylases
2009 StandoutNobel
Expanding the Substrate Tolerance of Biotin Ligase through Exploration of Enzymes from Diverse Species
2008
Two multifunctional peptide synthetases and an O-methyltransferase are involved in the biosynthesis of the DNA-binding antibiotic and antitumour agent saframycin Mx1 from Myxococcus xanthus
1996
Finding the Right (Bioorthogonal) Chemistry
2014
Antibiotics from Gliding Bacteria, LXIII. Ratjadone: A New Antifungal Metabolite from Sorangium cellulosum
1995
The Development of L2X2RuCHR Olefin Metathesis Catalysts: An Organometallic Success Story
2000 StandoutNobel
Alternate Heme Ligation Steers Activity and Selectivity in Engineered Cytochrome P450-Catalyzed Carbene-Transfer Reactions
2018 StandoutNobel
Multiple event activation of a generic prodrug trigger by antibody catalysis
1999 StandoutNobel
Vinylogous Mukaiyama aldol reactions with triarylboranes
2001
Terpene synthases are widely distributed in bacteria
2014 StandoutNobel
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
2020 StandoutNobel
CalFluors: A Universal Motif for Fluorogenic Azide Probes across the Visible Spectrum
2015 StandoutNobel
Z-Selective Copper-Catalyzed Asymmetric Allylic Alkylation with Grignard Reagents
2012 StandoutNobel
Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site
2023 StandoutNobel
Clean Inversion of Configuration in the Pd-Catalyzed Cross-Coupling of 2-Bromo-1,3-dienes
2003 StandoutNobel
Role of 2-Oxonia Cope Rearrangements in Prins Cyclization Reactions
2001
Catalytic Asymmetric Vinylogous Prins Cyclization: A Highly Diastereo- and Enantioselective Entry to Tetrahydrofurans
2016 StandoutNobel
A new Myxococcus xanthus gene cluster for the biosynthesis of the antibiotic saframycin Mx1 encoding a peptide synthetase
1995
Alkylidene and Metalacyclic Complexes of Tungsten that Contain a Chiral Biphenoxide Ligand. Synthesis, Asymmetric Ring-Closing Metathesis, and Mechanistic Investigations
2003 StandoutNobel
Works of Herbert Irschik being referenced
Insights into the complex biosynthesis of the leupyrrins in Sorangium cellulosum So ce690
2011
Epothilons A and B: Antifungal and Cytotoxic Compounds from Sorangium cellulosum (Myxobacteria). Production, Physico-chemical and Biological Properties.
1996
Chivosazol A, a New Inhibitor of Eukaryotic Organisms Isolated from Myxobacteria.
1995
Maracin and Maracen: New Types of Ethynyl Vinyl Ether andα-Chloro Divinyl Ether Antibiotics fromSorangium cellulosum with Specific Activity Against Mycobacteria
1998
The RNA Polymerase “Switch Region” Is a Target for Inhibitors
2008
Saframycin Mx1, a new natural saframycin isolated from a myxobacterium.
1988
The Jerangolids: A Family of New Antifungal Compounds from Sorangium cellulosum (Myxobacteria). Production, Physico-chemical and Biological Properties of Jerangolid A.
1996
Ratjadon: A New Antifungal Compound from Sorangium cellulosum (Myxobacteria) Production, Physico-chemical and Biological Properties.
1995
SorF: A Glycosyltransferase With Promiscuous Donor Substrate Specificity in vitro
2007
Thuggacins, Macrolide Antibiotics Active against Mycobacterium tuberculosis: Isolation from Myxobacteria, Structure Elucidation, Conformation Analysis and Biosynthesis
2007
The soraphens: A family of novel antifungal compounds from Sorangium cellulosum (myxobacteria). I. Soraphen A1.ALPHA.: Fermentation, isolation, biological properties.
1994
Antibiotics from gliding bacteria. No.60. The Tartrolons, New Boron-containing Antibiotics from a Myxobacterium, Sorangium cellulosum.
1995
Critical variations of conjugational DNA transfer into secondary metabolite multiproducing Sorangium cellulosum strains So ce12 and So ce56: development of a mariner-based transposon mutagenesis system
2003
Production of the Tubulin Destabilizer Disorazol in Sorangium cellulosum: Biosynthetic Machinery and Regulatory Genes
2005
Unusual Biosynthesis of Leupyrrins in the Myxobacterium Sorangium cellulosum
2004
Antibiotics from gilding bacteria. No.67. Sorangiolid A, a New Antibiotic Isolated from the Myxobacterium Sorangium cellulosumSo ce 12.
1995
Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity
2010
Antibiotics from gliding bacteria. No.62. Disorazol A, an Efflcient Inhibitor of Eukaryotic Organisms Isolated from Myxobacteria.
1995
Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
2005
Isolation and spectroscopic structure elucidation of sorangicin a, a new type of macrolide-polyether antibiotic from gliding bacteria - XXX.
1985
The sorangicins, novel and powerful inhibitors of eubacterial RNA polymerase isolated from myxobacteria.
1987
Antibiotika aus Gleitenden Bakterien, XXII. Die Biosynthese des Antibiotikums Myxopyronin A aus Myxococcus fulvus Stamm Mx f50
1984
Antibiotika aus Gleitenden Bakterien, XXXVII. Sorangicin A, ein hochwirksames Antibiotikum mit neuartiger Makrolid‐Polyether‐Struktur aus Sorangium cellulosum, So ce12: Spektroskopische Strukturaufklärung, Kristall‐ und Lösungsstruktur
1989
GE23077 binds to the RNA polymerase ‘i’ and ‘i+1’ sites and prevents the binding of initiating nucleotides
2014
Myxothiazol, an antibiotic from myxococcus fulvus. (myxobacterales) I. cultivation, isolation, physico-chemical and biological properties.
1980
The myxovirescins, a family of antibiotics from Myxococcus virescens (Myxobacterales).
1982
Antibiotics from Gliding Bacteria, LXXX. Chivosazoles A–F: Novel Antifungal and Cytotoxic Macrolides from Sorangium cellulosum (myxobacteria)
1997
Maracin und Maracen: neuartige Ethinylvinylether- bzw.α-Chlordivinylether-Antibiotica ausSorangium cellulosum mit spezifischer Wirkung gegen Mycobakterien
1998
The Leupyrrins: A Structurally Unique Family of Secondary Metabolites from the MyxobacteriumSorangiumcellulosum#
2003
The myxalamids, new antibiotics from Myxococcus xanthus (Myxobacterales) I. production, physico-chemical and biological properties, and mechanism of action.
1983
Tuscolid and Tuscoron A and B: Isolation, Structural Elucidation and Studies on the Biosynthesis of Novel Furan‐3(2H)‐one‐Containing Metabolites from the Myxobacterium Sorangium Cellulosum
2004
ChemInform Abstract: ANTIBIOTICS FROM GLIDING BACTERIA, XXII. BIOSYNTHESIS OF MYXOPYRONIN A, AN ANTIBIOTIC FROM MYXOCOCCUS FULVUS, STRAIN MX F50
1984
Antibiotics from gliding bacteria, LVII. Tartrolons: New boron‐containing macrodiolides from Sorangium cellulosum
1994
ChemInform Abstract: The Tartrolons, New Boron‐Containing Antibiotics from a Myxobacterium, Sorangium cellulosum.
1995
Antibiotika aus Gleitenden Bakterien, XXXV. Isolierung und Strukturaufklärung der Saframycine Mx 1 und Mx 2, neue antitumor‐aktive Antibiotika aus Myxococcus xanthus
1988
Antibiotics from Gliding Bacteria, LXXV. Absolute Configuration and Biosynthesis of Tartrolon B, a Boron‐Containing Macrodiolide from Sorangium cellulosum
1996
Antibiotics from Gliding Bacteria, LXXIII Indole and Quinoline Derivatives as Metabolites of Tryptophan in Myxobacteria
1996
ChemInform Abstract: Antibiotics from Gliding Bacteria. Part 53. The Soraphens: A Family of Novel Antifungal Compounds from Sorangium cellulosum (Myxobacteria). Part 1. Soraphen A1α: Fermentation, Isolation, Biological Properties.
1994
Opening and Closing of the Bacterial RNA Polymerase Clamp
2012 Science
Antibiotics from Gliding Bacteria, LIX. Disorazoles, Highly Cytotoxic Metabolites from the Sorangicin‐Producing Bacterium Sorangium Cellulosum, Strain So ce12
1994
Antibiotics from gliding bacteria, LXIV. Isolation and structure elucidation of sorangiolides A and B, novel macrocyclic lactone carboxylic acids from Sorangium cellulosum
1995
Etnangien, a Macrolide-Polyene Antibiotic from Sorangium cellulosum That Inhibits Nucleic Acid Polymerases
2007