Standout Papers
- Analysis of DNA mismatch repair proteins in human medulloblastoma. (1998)
Citation Impact
Citing Papers
Systemic CTLA-4 Blockade Ameliorates Glioma-Induced Changes to the CD4+ T Cell Compartment without Affecting Regulatory T-Cell Function
2007 StandoutNobel
Bayes Factors
1995 Standout
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
2001 Standout
Untangling the ErbB signalling network
2001 Standout
Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma
2008
Retrovirus-Mediated Gene Transfer of the Multidrug Resistance-Associated Protein (MRP) cDNA Protects Cells from Chemotherapeutic Agents
1997
Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease
2001
Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas
1995
Matrix metalloproteinases and the regulation of tissue remodelling
2007 Standout
Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449
2009 Standout
Molecular cytogenetic analysis of medulloblastomas and supratentorial primitive neuroectodermal tumors by using conventional banding, comparative genomic hybridization, and spectral karyotyping
2000
IDH1andIDH2Mutations in Gliomas
2009 Standout
Three‐Dimensional Reconstruction of Human α2‐Macroglobulin and Refinement of the Localization of Thiol Ester Bonds with Monomaleimido Nanogolda
1994 StandoutNobel
Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed and reactive site cleaved serpins: comparison of .alpha.1-proteinase inhibitor, .alpha.1-antichymotrypsin, antithrombin III, .alpha.2-antiplasmin, angiotensinogen, and ovalbumin
1991
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Structural basis for serpin inhibitor activity
1995
De novo protein design. I. in search of stability and specificity
1999 StandoutNobel
TGF-β signaling in tumor suppression and cancer progression
2001 Standout
Low-Density Lipoprotein Receptor-Related Protein-1 Mediates Endocytic Clearance of Tissue Inhibitor of Metalloproteinases-1 and Promotes Its Cytokine-Like Activities
2014 StandoutNobel
Hyaluronan: from extracellular glue to pericellular cue
2004 Standout
Large cell/anaplastic medulloblastomas and medullomyoblastomas: clinicopathological and genetic features
2001
Cellular Internalization and Degradation of Antithrombin III-Thrombin, Heparin Cofactor II-Thrombin, and α1-Antitrypsin-Trypsin Complexes Is Mediated by the Low Density Lipoprotein Receptor-related Protein
1996
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
1998 StandoutNobel
Plasminogen Activator Inhibitor-1 and Vitronectin Promote the Cellular Clearance of Thrombin by Low Density Lipoprotein Receptor-related Proteins 1 and 2
1996
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
2016 Standout
Mechanisms of Cellular Uptake of Thrombin-Antithrombin II Complexes Role of the Low-Density Lipoprotein Receptor-Related Protein as a Serpin-Enzyme Complex Receptor
1997
Chromosomes, 11q and cancer: a review
1999
Quantitative analysis of radioisotope cisternography in the diagnosis of intracranial hypotension
2004
Medulloblastoma in childhood: new biological advances
2007
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
RNA as a tumor vaccine: a review of the literature
2001
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas
1995 Standout
Targeting RAS signalling pathways in cancer therapy
2003 Standout
Modulating T-cell immunity to tumours: new strategies for monitoring T-cell responses
2002
Direct delivery of platinum-based antineoplastics to the central nervous system: a toxicity and ultrastructural study
1993
Crystal structure of cleaved human α1-antichymotrypsin at 2.7 å resolution and its comparison with other serpins
1991 Nobel
Risk factors for surgical site infections in neurosurgery patients with antibiotic prophylaxis
2005
In vivo catabolism of α1-antichymotrypsin is mediated by the Serpin receptor which binds α1-proteinase inhibitor, antithrombin III and heparin cofactor II
1988
EGF mutant receptor vIII as a molecular target in cancer therapy.
2001
Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
1995 Standout
Suppression of TGF-β1 in Human Gliomas by Retroviral Gene Transfection Enhances Susceptibility to LAK Cells
1999
Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1·95Å resolution
1992
C1 Inhibitor-C 1 ¯ s
1997
Spontaneous Spinal Cerebrospinal Fluid Leaks and Intracranial Hypotension
2006 Standout
The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases
1995
Therapeutic Cancer Vaccines
2013
Molecular Genetic Aspects of Oligodendrogliomas Including Analysis by Comparative Genomic Hybridization
1999
Zinc α-2-glycoprotein Regulates Melanin Production by Normal and Malignant Melanocytes
2002
Recurrent Ventriculoperitoneal Shunt Infection Caused by Small-Colony Variants of Staphylococcus aureus
2005
In vivo catabolism of heparin cofactor II and its complex with thrombin: Evidence for a common receptor-mediated clearance pathway for three serine proteinase inhibitors
1988
Extracellular mRNA Induces Dendritic Cell Activation by Stimulating Tumor Necrosis Factor-α Secretion and Signaling through a Nucleotide Receptor
2002 StandoutNobel
LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies
2008
A decade of exploring the cancer epigenome — biological and translational implications
2011 Standout
Identification of human brain tumour initiating cells
2004 StandoutNature
Role of the Proposed Serpin-Enzyme Complex Receptor Recognition Site in Binding and Internalization of Thrombin-Heparin Cofactor II Complexes by Hepatocytes
1996
Specificity of Serine Proteinase/Serpin Complex Binding to Very‐Low‐Density Lipoprotein Receptor and α2‐Macroglobulin Receptor/Low‐Density‐Lipoprotein‐Receptor‐Related Protein
1997
Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis
2010 Standout
Hormone binding globulins undergo serpin conformational change in inflammation
1988 Nature
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
New functions for the matrix metalloproteinases in cancer progression
2002 Standout
Solitary Fibrous Tumors and Hemangiopericytomas of the Meninges: Overlapping Pathological Features and Common Prognostic Factors Suggest the Same Spectrum of Tumors
2011
Primitive Neuroectodermal Tumors of the Central Nervous System
1997
Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management
2015 Standout
Proteolytic inactivation of alpha-1-anti-chymotrypsin. Sites of cleavage and generation of chemotactic activity.
1991
Overlapping roles for granulocyte-macrophage colony-stimulating factor and interleukin-3 in eosinophil homeostasis and contact hypersensitivity
2001
Binding of Ovarian Cancer Antigen CA125/MUC16 to Mesothelin Mediates Cell Adhesion
2004 Standout
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
1999 Standout
Interaction of the Tumor Suppressor PTEN/MMAC with a PDZ Domain of MAGI3, a Novel Membrane-associated Guanylate Kinase
2000 Standout
Serpin Structure, Mechanism, and Function
2002 Standout
Biology of Inherited Coagulopathies: Factor IX
1992
Circulating and binding characteristics of wild-type factor IX and certain Gla domain mutants in vivo
2002
The catabolism of intact, reactive centre-cleaved and proteinase-complexed C1 inhibitor in the guinea pig
1996
Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro
2005 StandoutNobel
A Coagulation Factor IX-Deficient Mouse Model for Human Hemophilia B
1997 StandoutNobel
Transforming growth factor-alpha-Pseudomonas exotoxin fusion protein (TGF-alpha-PE38) treatment of subcutaneous and intracranial human glioma and medulloblastoma xenografts in athymic mice.
1994
Electron microscopic identification of exposed plasmin epitopes in alpha 2-macroglobulin-plasmin complex using monoclonal antibody-colloidal gold adducts.
1988
Synergism of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Depletion of Cd25+ Regulatory T Cells in Antitumor Therapy Reveals Alternative Pathways for Suppression of Autoreactive Cytotoxic T Lymphocyte Responses
2001 StandoutNobel
T cell-mediated, IFN-gamma-facilitated rejection of murine B16 melanomas.
1998
Clearance of human native, proteinase-complexed, and proteolytically inactivated C1-inhibitor in rats
1993
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
Bone Marrow–generated Dendritic Cells Pulsed with Tumor Extracts or Tumor RNA Induce Antitumor Immunity against Central Nervous System Tumors
1997
The Origins of Medulloblastoma Subtypes
2008
Bayesian Methods in Practice: Experiences in the Pharmaceutical Industry
1986
PTEN gene mutations are seen in high-grade but not in low-grade gliomas.
1997
Intracoronary Adenovirus-Mediated Delivery and Overexpression of the β 2 -Adrenergic Receptor in the Heart
2000 StandoutNobel
Activation of coagulation releases endothelial cell mitogens.
1986
The 2007 WHO Classification of Tumours of the Central Nervous System
2010 Standout
Dendritic Cells Charged with Apoptotic Tumor Cells Induce Long-Lived Protective CD4+ and CD8+ T Cell Immunity against B16 Melanoma
2003 StandoutNobel
Immunobiology of Dendritic Cells
2000 Standout
Human Fibroblast Collagenase-α-Macroglobulin Interactions
1989
Induction of immunity to prostate cancer antigens: results of a clinical trial of vaccination with irradiated autologous prostate tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor using ex vivo gene transfer.
1999
T Cell-Mediated, IFN-γ-Facilitated Rejection of Murine B16 Melanomas
1998
Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of β cells
2007 StandoutNobel
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Immunotoxins for targeted cancer therapy
1998
Antigen-Specific Cytotoxicity by Invariant NKT Cells In Vivo Is CD95/CD178-Dependent and Is Correlated with Antigenic Potency
2010 StandoutNobel
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
1998 Standout
α-Macroglobulins: structure, shape, and mechanism of proteinase complex formation
1989
Interaction of wild-type and catalytically inactive mutant forms of tissue-type plasminogen activator with human umbilical vein endothelial cell monolayers.
1990
A Pilot Trial of CTLA-4 Blockade with Human Anti-CTLA-4 in Patients with Hormone-Refractory Prostate Cancer
2007 StandoutNobel
Cancerous stem cells can arise from pediatric brain tumors
2003 Standout
Functions of Cell Surface Heparan Sulfate Proteoglycans
1999 Standout
The biology of platelet-derived growth factor
1986 Standout
Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
2000 StandoutScience
Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.
1987 Standout
Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors
2000
Overexpression of Hyaluronan Synthase-2 Reduces the Tumorigenic Potential of Glioma Cells Lacking Hyaluronidase Activity
2002
Works of Herbert E. Fuchs being referenced
Risk Factors for Pediatric Ventriculoperitoneal Shunt Infection and Predictors of Infectious Pathogens
2003
Chronic CSF Leak Into the Peritoneal Cavity Shown by Radionuclide Cisternography:
1997
Prognostic implications of chromosome 17p deletions in human medulloblastomas
1995
Immunology of Transplantation in the Central Nervous Sylftem
1988
Microsatellite analysis of childhood brain tumors
1996
Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system.
1996
Activity of intrathecal 4-hydroperoxycyclophosphamide in a nude rat model of human neoplastic meningitis.
1990
In vivo catabolism of α1-proteinase inhibitor-trypsin, antithrombin III-thrombin and α2-macroglobulin-methylamine
1982
Regulation of factor IXa in vitro in human and mouse plasma and in vivo in the mouse. Role of the endothelium and the plasma proteinase inhibitors.
1984
A Unique Pathway for the Plasma Elimination of α2-Antiplasmin-Protease Complexes in Mice
1982
Hepatocyte receptors for antithrombin III‐proteinase complexes
1984
[18F]Fluorodeoxyglucose-Positron Emission Tomography in Patients with Medulloblastoma
2004
Characterization of a Spontaneous Murine Astrocytoma and Abrogation of Its Tumorigenicity by Cytokine Secretion
1997
Specificity of α2-Macroglobulin Covalent Cross-Linking for the Active Domain of Proteinases
1986
Solitary fibrous tumor of the meninges occurring after irradiation of a mixed germ cell tumor of the pineal gland.
1998
A new approach to minimizing the number of animals used in acute toxicity testing and optimizing the information of test results
1982
Hepatocyte uptake of α1‐proteinase inhibitor‐trypsin complexes in vitro: Evidence for a shared uptake mechanism for proteinase complexes of α1‐proteinase inhibitor and antithrombin III
1984
Intrathecal administration of single-chain immunotoxin, LMB-7 [B3(Fv)-PE38], produces cures of carcinomatous meningitis in a rat model.
1995