Standout Papers
Citation Impact
Citing Papers
Treatment of Ischemic Brain Damage by Perturbing NMDA Receptor- PSD-95 Protein Interactions
2002 Science
Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor
2002 StandoutScience
Hallmarks of Cancer: The Next Generation
2011 Standout
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia
1990
Changes in extracellular amino acid neurotransmitters produced by focal cerebral ischemia
1990
Mechanisms of Thrombus Formation
2008 Standout
Apoptosis in the nervous system
2000 StandoutNature
Synergistic effects of caspase inhibitors and MK‐801 in brain injury after transient focal cerebral ischaemia in mice
1998
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
The neuroprotective actions of kynurenic acid and MK-801 in gerbils are synergistic and not related to hypothermia
1990
X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel
2014 StandoutNobel
Hypertension in mice lacking the gene for endothelial nitric oxide synthase
1995 StandoutNature
Hyperthermia nullifies the ameliorating effect of dizocilpine maleate (MK-801) in focal cerebral ischemia
1995
Historical Overview
1988
Roles of individual prolyl‐4‐hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice
2012 StandoutNobel
The glutamate antagonist MK‐801 reduces focal ischemic brain damage in the rat
1988
Effect of Noncompetitive Blockade of N‐Methyl‐d‐Aspartate Receptors on the Neurochemical Sequelae of Experimental Brain Injury
1990
Formation of Precise Connections in the Olfactory Bulb Occurs in the Absence of Odorant-Evoked Neuronal Activity
2000 StandoutNobel
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Attenuation of Delayed Neuronal Death after Mild Focal Ischemia in Mice by Inhibition of the Caspase Family
1998
Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke.
1996
Application of continuous relaxation time distributions to the fitting of data from model systmes and excised tissue
1991
Reduction by delayed hypothermia of cerebral infarction following middle cerebral artery occlusion in the rat: a time-course study
1992
Cerebroprotective Effect of the Nitric Oxide Synthase Inhibitors, 1-(2-Trifluoromethylphenyl) Imidazole and 7-Nitro Indazole, after Transient Focal Cerebral Ischemia in the Rat
1998
Reduced Brain Edema and Infarction Volume in Mice Lacking the Neuronal Isoform of Nitric Oxide Synthase after Transient MCA Occlusion
1996
Laminin Peptide Ameliorates Brain Injury by Inhibiting Leukocyte Accumulation in a Rat Model of Transient Focal Cerebral Ischemia
1997
Information coding in the olfactory system: Evidence for a stereotyped and highly organized epitope map in the olfactory bulb
1994 StandoutNobel
The effect of the excitatory amino acid receptor antagonist dizocilipine maleate (MK-801) on hemispheric cerebral blood flow and metabolism in dogs: modification by prior complete cerebral ischemia
1989
Dual role of nitric oxide in focal cerebral ischemia
1994
Lipid peroxidation in focal cerebral ischemia
1989
α-Phenyl-tert-butyl-nitrone reduces cortical infarct and edema in rats subjected to focal ischemia
1994
Hydroxyl Radical Formation in Hyperglycemic Rats During Middle Cerebral Artery Occlusion/Reperfusion
1997
The Immunosuppressant Drug FK506 Ameliorates Secondary Mitochondrial Dysfunction Following Transient Focal Cerebral Ischemia in the Rat
1997
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Mild Hypothermia and MK-801 Have Similar But Not Additive Degrees of Cerebroprotection in the Rat Permanent Focal Ischemia Model
1994
Effect of transient focal ischemia on blood-brain barrier permeability in the rat: correlation to cell injury
1997
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
1993 StandoutNature
Natural RNA circles function as efficient microRNA sponges
2013 StandoutNature
Novel Docosanoids Inhibit Brain Ischemia-Reperfusion-mediated Leukocyte Infiltration and Pro-inflammatory Gene Expression
2003
Glial and neuronal control of brain blood flow
2010 StandoutNature
Protective and Damaging Effects of Stress Mediators
1998 Standout
Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains
1996 Standout
Neuroprotection in Ischemia
2004
Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms
1991 Standout
Ischemic Brain Injury is Mediated by the Activation of Poly(ADP-Ribose)Polymerase
1997
Target-independent pattern specification in the olfactory epithelium
1995 StandoutNobel
Capillary pericytes regulate cerebral blood flow in health and disease
2014 StandoutNature
Prevention of a First Stroke by Transfusions in Children with Sickle Cell Anemia and Abnormal Results on Transcranial Doppler Ultrasonography
1998 Standout
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia
1997
Kynurenine Pathway Measurements in Huntington's Disease Striatum: Evidence for Reduced Formation of Kynurenic Acid
1990
Interplay between Cortical Spreading Depolarization and Seizures
2017 Standout
The effect of the NMDA receptor antagonist MK-801 on cerebral blood flow and infarct volume in experimental focal stroke
1992
Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat
2006
The excitatory amino acid antagonist kynurenic acid administered after hypoxic-ischemia in neonatal rats offers neuroprotection
1988
The effect of nimodipine and dextran on axonal function and blood flow following experimental spinal cord injury
1989
In vivo Models of Cerebral Ischemia: Effects of Parenterally Administered NMDA Receptor Glycine Site Antagonists
1995
The effect of intracerebral hematoma location on the risk of brain-stem compression and on clinical outcome
1988
Neuron-Specific Inactivation of the Hypoxia Inducible Factor 1 Increases Brain Injury in a Mouse Model of Transient Focal Cerebral Ischemia
2007
Ectopic Expression of the Catalytic Subunit of Telomerase Protects against Brain Injury Resulting from Ischemia and NMDA-Induced Neurotoxicity
2004
Activated Protein C Reduces the Ischemia/Reperfusion-Induced Spinal Cord Injury in Rats by Inhibiting Neutrophil Activation
2000
Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis
2001 Standout
In vivo photoacoustic tomography of mouse cerebral edema induced by cold injury
2011
Comparative analysis of brain protection by N-methyl-D-aspartate receptor antagonists after transient focal ischemia in cats
1997
Excitatory Amino Acids as a Final Common Pathway for Neurologic Disorders
1994 Standout
Effect of 21-aminosteroid lipid peroxidation inhibitor, U74006F, in the rat middle cerebral artery occlusion model
1994
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Intercellular adhesion molecule‐1‐deficient mice are less susceptible to cerebral ischemia‐reperfusion lnjury
1996
Two-Photon Imaging of Cortical Surface Microvessels Reveals a Robust Redistribution in Blood Flow after Vascular Occlusion
2005
Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat
1992
The molecular neurobiology of depression
2008 StandoutNature
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Hypoxia-inducible Factor Prolyl 4-Hydroxylase Inhibition
2005
Calcium Channel Antagonists in the Prevention of Neurotoxicity
1991
Glyceraldehyde-3-phosphate dehydrogenase versus toluidine blue as a marker for infarct volume estimation following permanent middle cerebral artery occlusion in mice
2006
Spontaneous Intracerebral Hemorrhage
2001 Standout
Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat.
1992
Oxidants, antioxidants, and the degenerative diseases of aging.
1993 Standout
Focal Cerebral Ischemia in the Cat: Pretreatment with a Competitive NMDA Receptor Antagonist, D-CPP-ene
1990
Cortical Protection by Localized Striatal Injection of IL-1ra Following Cerebral Ischemia in the Rat
1997
An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain
2003 StandoutNobel
Reperfusion increases neutrophils and leukotriene B4 receptor binding in rat focal ischemia.
1992
A Reproducible Model of Middle Cerebral Artery Occlusion in Mice: Hemodynamic, Biochemical, and Magnetic Resonance Imaging
1998
Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo
1995
Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats.
1993
Focal ischemia causes an extensive induction of immediate early genes that are sensitive to MK-801.
1994
Cerebroprotective Effect of Lamotrigine After Focal Ischemia in Rats
1995
The Medial Temporal Lobe Memory System
1991 StandoutScience
Postischemic administration of FK506 reduces infarct volume following transient focal brain ischemia
1996
Effect of the NMDA Antagonist MK-801 on Local Cerebral Blood Flow in Focal Cerebral Ischaemia in the Rat
1989
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Comparative histopathologic consequences of photothrombotic occlusion of the distal middle cerebral artery in Sprague-Dawley and Wistar rats.
1993
Mice Deficient in Cellular Glutathione Peroxidase Show Increased Vulnerability to Malonate, 3-Nitropropionic Acid, and 1-Methyl-4-Phenyl-1,2,5,6-Tetrahydropyridine
2000 Standout
Activation and Cleavage of Caspase-3 in Apoptosis Induced by Experimental Cerebral Ischemia
1998
The N-methyl-D-aspartate antagonist, MK-801, fails to protect against neuronal damage caused by transient, severe forebrain ischemia in adult rats
1991
Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat.
1993
Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.
1992 StandoutNobel
The Effects of a Competitive NMDA Receptor Antagonist (CGS-19755) on Cerebral Blood Flow and pH in Focal Ischemia
1991
Extracellular Potassium in a Neocortical Core Area After Transient Focal Ischemia
1997
Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury
1989
Inhibition of interleukin 1β converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage
1997
Focal Brain Ischemia in the Rat: Methods for Reproducible Neocortical Infarction Using Tandem Occlusion of the Distal Middle Cerebral and Ipsilateral Common Carotid Arteries
1988
Blood—Brain Barrier Permeability and Brain Concentration of Sodium, Potassium, and Chloride during Focal Ischemia
1994
Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia.
1994
Penetration of Drugs through the Blood-Cerebrospinal Fluid/Blood-Brain Barrier for Treatment of Central Nervous System Infections
2010 Standout
Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs
2012 StandoutScience
Delayed Antagonism of Calpain Reduces Excitotoxicity in Cultured Neurons
1995
Transient Middle Cerebral Artery Occlusion by Intraluminal Suture: II. Neurological Deficits, and Pixel-Based Correlation of Histopathology with Local Blood Flow and Glucose Utilization
1997
Six-Hour Window of Opportunity for Calpain Inhibition in Focal Cerebral Ischemia in Rats
1998
Ischemic Cell Death in Brain Neurons
1999 Standout
Nimodipine attenuates both increase in cytosolic free calcium and histologic damage following focal cerebral ischemia and reperfusion in cats.
1989
Neurological Deficit and Extent of Neuronal Necrosis Attributable to Middle Cerebral Artery Occlusion in Rats
1995
Regional cerebral blood flow and histopathologic changes after middle cerebral artery occlusion in rats.
1989
Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase
1994 Science
Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage
1988 Standout
Matrix Metalloproteinase Expression Increases After Cerebral Focal Ischemia in Rats
1998
Procedural and Strain-related Variables Significantly Affect Outcome in a Murine Model of Focal Cerebral Ischemia
1996
The NOS Inhibitor, 7-Nitroindazole, Decreases Focal Infarct Volume but Not the Response to Topical Acetylcholine in Pial Vessels
1994
Postnatal construction of neural circuitry in the mouse olfactory bulb
1990
Liposome-entrapped superoxide dismutase reduces cerebral infarction in cerebral ischemia in rats.
1990
Differential Hydroxylation of Salicylate in Core and Penumbra Regions During Focal Reversible Cerebral Ischemia
1997
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
YM872, a Highly Water-Soluble AMPA Receptor Antagonist, Preserves the Hemodynamic Penumbra and Reduces Brain Injury After Permanent Focal Ischemia in Rats
1998
Oxidative Stress, Glutamate, and Neurodegenerative Disorders
1993 StandoutScience
Anatomic variation of the middle cerebral artery in the Sprague-Dawley rat.
1993
The Calmodulin Antagonist Trifluoperazine in Transient Focal Brain Ischemia in Rats
1997
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging.
1992 Standout
Nimodipine posttreatment does not increase blood flow in rats with focal cortical ischemia.
1990
Attenuation of Focal Ischemic Brain Injury in Mice Deficient in the ε1 (NR2A) Subunit of NMDA Receptor
1998
Stroke with negative brain magnetic resonance imaging.
1992
Effect of MK-801 on focal brain infarction in normotensive and hypertensive rats.
1992
Attenuation of Transient Focal Cerebral Ischemic Injury in Transgenic Mice Expressing a Mutant ICE Inhibitory Protein
1997
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
A Selective N-Type Calcium Channel Antagonist Reduces Extracellular Glutamate Release and Infarct Volume in Focal Cerebral Ischemia
1995
Competitive N-methyl-D-aspartate receptor blockade reduces brain injury following transient focal ischemia in cats.
1994
Rodent models of cerebral ischemia.
1989
The Cytolytic P 2Z Receptor for Extracellular ATP Identified as a P 2X Receptor (P2X 7 )
1996 StandoutScience
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis
2006
EAT-4, a Homolog of a Mammalian Sodium-Dependent Inorganic Phosphate Cotransporter, Is Necessary for Glutamatergic Neurotransmission inCaenorhabditis elegans
1999 StandoutNobel
Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase.
1991
The Quantification of Cerebral Infarction following Focal Ischemia in the Rat: Influence of Strain, Arterial Pressure, Blood Glucose Concentration, and Age
1988
Delayed Treatment with Aminoguanidine Decreases Focal Cerebral Ischemic Damage and Enhances Neurologic Recovery in Rats
1998
Reversible middle cerebral artery occlusion without craniectomy in rats.
1989 Standout
Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes
1992 StandoutScienceNobel
Works of Henry M. Bartkowski being referenced
The specific NMDA receptor antagonist AP-7 attenuates focal ischemic brain injury
1989
Kynurenate inhibition of cell excitation decreases stroke size and deficits
1987
Pharmacokinetics, cerebrospinal fluid concentration, and safety of intravenous rifampin in pediatric patients undergoing shunt placements
1990
Outcome from severe head injury in children and adolescents
1985
MR imaging and spectroscopy in clinical and experimental cerebral ischemia: a review
1987
The therapeutic value of nimodipine in experimental focal cerebral ischemia
1987
Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.
1986 Standout
Nuclear magnetic resonance studies in normal and edematous brain tissue
1975
Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats.
1986 Standout
Traumatic Intracerebral Hematomas: Timing of Appearance and Indications for Operative Removal
1986
Nuclear magnetic resonance imaging and spectroscopy in experimental brain edema in a rat model
1986