Citation Impact
Citing Papers
Structural Basis of Transcription Initiation
2012 Science
An Engineered Microbial Platform for Direct Biofuel Production from Brown Macroalgae
2012 StandoutScienceNobel
Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease
2010 StandoutScienceNobel
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
2012 StandoutScienceNobel
Structural Basis of Transcription Initiation: An RNA Polymerase Holoenzyme-DNA Complex
2002 Science
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Structures of the RNA-guided surveillance complex from a bacterial immune system
2011 StandoutNatureNobel
A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action
2006
Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP
1985 StandoutNatureNobel
Crystallization of Escherichia coli catabolite gene activator protein with its DNA binding site
1990 StandoutNobel
Essential role of mouse telomerase in highly proliferative organs
1998 StandoutNatureNobel
Synthetic DNA bending sequences increase the rate of in vitro transcription initiation at the Escherichia coli lac promoter
1991
H2A.Z-Mediated Localization of Genes at the Nuclear Periphery Confers Epigenetic Memory of Previous Transcriptional State
2007
The Transition to an Elongation Complex by T7 RNA Polymerase Is a Multistep Process
2007
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding
1993 StandoutNatureNobel
T7 promoter release mediated by DNA scrunching
2001
Active genes at the nuclear pore complex
2007
Structural basis for initiation of transcription from an RNA polymerase–promoter complex
1999 StandoutNatureNobel
Interactions between the Escherichia coli cyclic AMP receptor protein and RNA polymerase at Class II promoters
1993
Characterization of halted T7 RNA polymerase elongation complexes reveals multiple factors that contribute to stability 1 1Edited by M. Gottesman
2000
Telomere states and cell fates
2000 StandoutNatureNobel
Structural Transitions Mediating Transcription Initiation by T7 RNA Polymerase
2002
Synergy between Escherichia coli CAP protein and RNA polymerase in the lac promoter open complex
1989
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
Orientation of functional activating regions in the Escherichia coli CRP protein during transcription activation at class II promoters
1996
Mutagenesis of the cyclic AMP receptor protein ofEscherichia coli: targeting positions 83, 127 and 128 the cyclic nucleotide binding pocket
1994
Position and orientation of the globular domain of linker histone H5 on the nucleosome
1998 StandoutNatureNobel
The Nuclear Exosome and Adenylation Regulate Posttranscriptional Tethering of Yeast GAL Genes to the Nuclear Periphery
2008 StandoutNobel
HIV-1-resistance phenotype conferred by combination of two separate inherited mutations of CCR5 gene
1998 StandoutNobel
Structural studies of protein–nucleic acid interaction: the sources of sequence-specific binding
1990 StandoutNobel
Transcription Initiation in a Single-Subunit RNA Polymerase Proceeds through DNA Scrunching and Rotation of the N-Terminal Subdomains
2008
HIV-1 Genome Nuclear Import Is Mediated by a Central DNA Flap
2000 StandoutNobel
Integration host factor stimulates the phage lambda pL promoter
1990
Major Conformational Changes Occur during the Transition from an Initiation Complex to an Elongation Complex by T7 RNA Polymerase
2002
Icy: an open bioimage informatics platform for extended reproducible research
2012
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Three-dimensional structure of Escherichia coli RNA polymerase holoenzyme determined by electron crystallography
1989 StandoutNatureNobel
Structure of the Bacterial RNA Polymerase Promoter Specificity σ Subunit
2002
DNA sequence determinants of CAP-induced bending and protein binding affinity
1988 Nature
Structural Organization of the RNA Polymerase-Promoter Open Complex
2000
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
DNA Bending Induced by the Catabolite Activator Protein Allows Ring Formation of a 144 bp DNA
1987
Electrostatic calculations and model‐building suggest that DNA bound to CAP is sharply bent
1987 StandoutNobel
Complexes of yeast RNA polymerase II and RNA are substrates for TFIIS-induced RNA cleavage
1994
MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
2002 StandoutNatureNobel
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Fluorescence ratio imaging of cyclic AMP in single cells
1991 StandoutNatureNobel
Rescue of bicoid mutant Drosophila embryos by Bicoid fusion proteins containing heterologous activating sequences
1989 StandoutNatureNobel
The catalytic subunit of cAMP-dependent protein kinase induces expression of genes containing cAMP-responsive enhancer elements
1988 Nature
Structural biology of the PCI-protein fold
2012
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
The allosteric transition of glycogen phosphorylase
1989 Nature
Structure of a T7 RNA polymerase elongation complex at 2.9 Å resolution
2002 Nature
Regulation of gene expression by transfected subunits of cAMP‐dependent protein kinase
1990
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Quorum sensing inVibrio fischeri: elements of theluxIpromoter
1999
Transcription elongation: structural basis and mechanisms
1999
Sus1, Sac3, and Thp1 mediate post-transcriptional tethering of active genes to the nuclear rim as well as to non-nascent mRNP
2007 StandoutNobel
Nuclear pore association confers optimal expression levels for an inducible yeast gene
2006 Nature
Crystallographic Studies of Protein-Nucleic Acid Interaction: Catabolite Gene Activator Protein and the Large Fragment of DNA Polymerase I
1983
The Definition of Generalized Helicoidal Parameters and of Axis Curvature for Irregular Nucleic Acids
1988
3′‐end formation signals modulate the association of genes with the nuclear periphery as well as mRNP dot formation
2006 StandoutNobel
A synthetic multicellular system for programmed pattern formation
2005 StandoutNatureNobel
Local Supercoil-Stabilized DNA Structure
1991
Escherichia coli cAMP receptor protein: evidence for three protein conformational states with different promoter binding affinities
1989
The telomerase reverse transcriptase: components and regulation
1998
The role of two surface exposed loops in tranction activation by theEscherichia ColiCRP and FNR proteins
1991
Thermodynamics of Cyclic Nucleotide Binding to the cAMP Receptor Protein and Its T127L Mutant
1995
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
Lysine 188 of the catabolite gene activator protein (CAP) plays no role in specificity at base pair 7 of the DNA half site
1990
The locus of sequence-directed and protein-induced DNA bending
1984 StandoutNature
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Recognition sequence of specific endonuclease BamHI from Bacillus amyloliquefaciens H
1977 StandoutNatureNobel
The intracellular signal for induction of resistance to alkylating agents in E. coli
1986 StandoutNobel
The Structure of a Transcribing T7 RNA Polymerase in Transition from Initiation to Elongation
2008 StandoutScienceNobel
Model of specific complex between catabolite gene activator protein and B-DNA suggested by electrostatic complementarity.
1984 StandoutNobel
NIH Image to ImageJ: 25 years of image analysis
2012 Standout
On the different binding affinities of CRP at thelac, galandmalT promoter regions
1983
The Major Phase-Variable Outer Membrane Protein of Escherichia coli Structurally Resembles the Immunoglobulin A1 Protease Class of Exported Protein and Is Regulated by a Novel Mechanism Involving Dam and OxyR
1999
On the action of the cyclic AMP-cyclic AMP receptor protein complex at the Escherichia coli lactose and galactose promoter regions.
1984
Unusual properties of promoter-up mutations in the Escherichia coli galactose operon and evidence suggesting RNA polymerase-induced DNA bending.
1987
Determination of the orientation of a DNA binding motif in a protein-DNA complex by photocrosslinking.
1992
Catabolite gene activator protein activation of lac transcription
1992
Binding of the cyclic AMP receptor protein of Escherichia coli to RNA polymerase
1988
Characterization of (+) Strand Initiation and Termination Sequences Located at the Center of the Equine Infectious Anemia Virus Genome
1999
Footprinting analysis of mammalian RNA polymerase II along its transcript: an alternative view of transcription elongation.
1991
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution
2001 StandoutScienceNobel
[7] Uses of transposons with emphasis on Tn10
1991
Interactions of Escherichia coli σ 70 within the transcription elongation complex
1999
Two helix DNA binding motif of CAP found inlacrepressor andgalrepressor
1982
Topological and Conformational Analysis of the Initiation and Elongation Complex of T7 RNA Polymerase Suggests a New Twist
2004
Identification of a contact between arginine-180 of the catabolite gene activator protein (CAP) and base pair 5 of the DNA site in the CAP-DNA complex.
1990
Promoter Recognition As Measured by Binding of Polymerase to Nontemplate Strand Oligonucleotide
1997 Science
Escherichia coli cyclic AMP receptor protein mutants provide evidence for ligand contacts important in activation
1992
Telomerase Catalytic Subunit Homologs from Fission Yeast and Human
1997 StandoutScienceNobel
Cyclic AMP Regulation of Eukaryotic Gene Transcription by Two Discrete Molecular Mechanisms
1985 Science
Cotranscriptional Recruitment to the mRNA Export Receptor Mex67p Contributes to Nuclear Pore Anchoring of Activated Genes
2006
Structural Confirmation of a Bent and Open Model for the Initiation Complex of T7 RNA Polymerase
2007
ALTERNATIVE PROMOTERS IN DEVELOPMENTAL GENE EXPRESSION
1987
Mutants of the catabolite activator protein of Escherichia coli that are specifically deficient in the gene-activation function.
1987
Variations of intramolecular ligation rates allow the detection of protein-induced bends in DNA.
1986
Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°
1991 StandoutScienceNobel
HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway
1997
Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA
1993 StandoutScienceNobel
The DNA binding domain and bending angle of E. coli CAP protein
1986
Specific DNA binding of the cAMP receptor protein within the lac operon stabilizes double-stranded DNA in the presence of cAMP.
1983
Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast
1986
Architecture of RNA Polymerase II and Implications for the Transcription Mechanism
2000 StandoutScienceNobel
Selection of DNA binding sites by regulatory proteins
1987
The structure of a CAP–DNA complex having two cAMP molecules bound to each monomer
1997 StandoutNobel
The specificity loop of T7 RNA polymerase interacts first with the promoter and then with the elongating transcript, suggesting a mechanism for promoter clearance
2000
Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase
2002 StandoutScienceNobel
Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms
2004 StandoutScienceNobel
In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector
1996 StandoutScience
Neurexins: Synaptic Cell Surface Proteins Related to the α-Latrotoxin Receptor and Laminin
1992 StandoutScienceNobel
Mutations that alter the allosteric nature of cAMP receptor protein of Escherichia coli.
1985
Structure of E. coli Glutaminyl-tRNA Synthetase Complexed with tRNA Gln and ATP at 2.8 Å Resolution
1989 StandoutScienceNobel
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Rewriting a genome
2013 StandoutNatureNobel
Role of glutamic acid-181 in DNA-sequence recognition by the catabolite gene activator protein (CAP) of Escherichia coli: altered DNA-sequence-recognition properties of [Val181]CAP and [Leu181]CAP.
1987
Synthetic curved DNA sequences can act as transcriptional activators in Escherichia coli.
1989
Application of fluorescence energy transfer and polarization to monitor Escherichia coli cAMP receptor protein and lac promoter interaction.
1990
Fragments of the HIV-1 Tat Protein Specifically Biand TAR RNA
1990 StandoutScienceNobel
Interactions of the RNA polymerase of bacteriophage T7 with its promoter during binding and initiation of transcription.
1986
Restriction Endonuclease
1976 StandoutNobel
Identifying protein-binding sites from unaligned DNA fragments.
1989
The change of DNA structure by specific binding of the cAMP receptor protein from rotation diffusion and dichroism measurements.
1984
Mutations that alter the DNA sequence specificity of the catabolite gene activator protein of E. coli
1984 Nature
Escherichia coli catabolite gene activator protein mutants defective in positive control of lac operon transcription
1991
Works of Henri Buc being referenced
E.coliRNA polymerase, deleted in the C-terminal part of its α-subunit, interacts differently with the cAMP-CRP complex at thelacP1 and at thegaP1 promoter
1993
The Kinetics of Sigma Subunit Directed Promoter Recognition by E. coli RNA Polymerase
1999
Retroviral recombination: what drives the switch?
2001
Structural kinetics of transcription activation at the malT promoter of Escherichia coli by UV laser footprinting
1997
SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope
2006 Nature
Upstream curved sequences influence the initiation of transcription at the Escherichia coli galactose operon
1992
Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria
1990
Protein-DNA cross-linking at thelacpromoter
1991
Stringent spacing requirements for transcription activation by CRP
1990
Mutations that alter the ability of theEscherichia colicyclic AMP receptor protein to activate transcription
1990
Fine mapping of DNA single-stranded regions using base-specific chemical probes. Study of an open complex formed between RNA polymerase and the lac UV5 promoter
1989
HIV-1 Reverse Transcription A Termination Step at the Center of the Genome
1994
On the Binding of tRNA to Escherichia coli RNA Polymerase. Interactions between the Core Enzyme, DNA and tRNA
1981
Studies of Contacts between T7 RNA Polymerase and Its Promoter Reveal Features in Common with Multisubunit RNA Polymerases
1999
A Reiterative Mode of DNA Synthesis Adopted by HIV-1 Reverse Transcriptase after a Misincorporation
1996
On the Binding of tRNA to Escherichia coli RNA Polymerase
1979
Hla, anE. coliDNA-binding protein which accumulates in stationary phase, strongly compacts DNAin vitro
1984
Cyclic AMP Receptor Protein: Role in Transcription Activation
1984 Science
Is DNA unwound by the cyclic AMP receptor protein?
1982
Kinetics of open complex formation between Escherichia coli RNA polymerase and the lac UV5 promoter. Evidence for a sequential mechanism involving three steps
1985
Mechanism of allosteric activation of glycogen phosphorylase probed by the reactivity of essential arginyl residues. Physicochemical and kinetic studies
1980
Deletion mutagenesis of the Escherichia coli galactose operon promoter region
1983
A Reiterative Mode of DNA Synthesis Adopted by HIV-1 Reverse Transcriptase after a Misincorporation
1997
The Reactivity of Arginine Residues Interacting with Glucose 1‐Phosphate in Glycogen Phosphorylase
1983
Preparative purification of λ‐DNA fragments obtained after Eco RI digestion
1975
Mechanism of CRP-cAMP activation of lac operon transcription initiation activation of the P1 promoter
1984
The selection and characterization of two novel mutations in the overlapping promoters of the Escherichia coli galactose operon
1984