Citation Impact

Citing Papers

Hydrogen peroxide sensing, signaling and regulation of transcription factors
2014
Size dependent translocation and fetal accumulation of gold nanoparticles from maternal blood in the rat
2014
A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity
2010
Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1
1999
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
Biodistribution and toxicity of engineered gold nanoparticles: a review of in vitro and in vivo studies
2010
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Oncogenic kinase signalling
2001 StandoutNature
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Molecular Regulation of the Endothelin-1 Gene by Hypoxia
2001
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
The Novel ATM-Related Protein TRRAP Is an Essential Cofactor for the c-Myc and E2F Oncoproteins
1998
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
2004 StandoutNature
Multimodal drug delivery using gold nanoparticles
2009
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product
1988 StandoutNature
Biological applications of gold nanoparticles
2008
DNp73 Exerts Function in Metastasis Initiation by Disconnecting the Inhibitory Role of EPLIN on IGF1R-AKT/STAT3 Signaling
2013
Ectopic Expression of Nonliganded Retinoic Acid Receptor β Abrogates AP-1 Activity by Selective Degradation of c-Jun in Cervical Carcinoma Cells
2004 StandoutNobel
The SWI/SNF complex and cancer
2009
Fsel, a new type II restriction endonuclease that recognizes the octanucleotide sequence 5′ GGCCGGCC 3′
1990 StandoutNobel
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
1991 StandoutNobel
Huntingtin Is Present in the Nucleus, Interacts with the Transcriptional Corepressor C-terminal Binding Protein, and Represses Transcription
2002
Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?
2010
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1992 StandoutNature
Inflammation in atherosclerosis
2002 StandoutNature
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
The relevance of shape and size of Au55 clusters
2008
Gold Nanoparticles of Diameter 1.4 nm Trigger Necrosis by Oxidative Stress and Mitochondrial Damage
2009
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
Gold nanoparticle platforms as drug and biomacromolecule delivery systems
2010
The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone
1988 StandoutNobel
Gold nanoparticles in biomedical applications: recent advances and perspectives
2011 Standout
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus
2005
Roles of PPARs in health and disease
2000 StandoutNature
Nanopharmacy: Inorganic nanoscale devices as vectors and active compounds
2010
The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos
1993 StandoutNobel
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
p73: Friend or foe in tumorigenesis
2002
Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein
1995 StandoutNatureNobel
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis
1986 StandoutScience
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
1983 StandoutNature
Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes.
1986
Identification of adenovirus 2 early region 4 polypeptides by in vitro translation and tryptic peptide map analysis
1982
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
Adenovirus terminal protein precursor. Partial amino acid sequence and the site of covalent linkage to virus DNA.
1982
Two functions encoded by adenovirus early region 1A are responsible for the activation and repression of the DNA-binding protein gene.
1985
The nucleotide sequence of the transforming early region E1 of adenovirus type 5 DNA
1980
Mechanisms of transcriptional dysregulation in Huntington's disease
2003
Detection of cellular proteins associated with human adenovirus type 5 early region 1A polypeptides
1985
Transformation-deficient adenovirus mutant defective in expression of region 1A but not region 1B
1982
Lytic and transforming functions of individual products of the adenovirus E1A gene
1986 StandoutNobel
Adenovirus E1a proteins repress transcription from the SV40 early promoter
1985
Localization of the adenovirus E1Aa protein, a positive-acting transcriptional factor, in infected cells infected cells.
1983
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
2002 StandoutNobel
Nucleotide sequence of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, a glycoprotein of endoplasmic reticulum
1984 StandoutNatureNobel
CBP/p300 in cell growth, transformation, and development
2000
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
2002 StandoutNobel
Expression of early adenovirus genes requires a viral encoded acidic polypeptide.
1981
The relationship between region E1a and E1b of human adenoviruses in cell transformation
1982
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
An adenovirus type 2 glycoprotein blocks cell surface expression of human histocompatibility class I antigens
1985
Isolation of type 5 adenovirus mutants with a cold-sensitive host range phenotype: Genetic evidence of an adenovirus transformation maintenance function
1982
The protein products of the myc and myb oncogenes and adenovirus E1a are structurally related
1983 StandoutNatureNobel
Adenovirus E1a Gene Product Expressed at High Levels in Escherichia coli Is Functional
1984 Science
Viral messenger RNAs in six lines of adenovirus-transformed cells
1981
Ligand-Activated Retinoic Acid Receptor Inhibits AP-1 Transactivation by Disrupting c-Jun/c-Fos Dimerization
1999
Role of the p53-homologue p73 in E2F1-induced apoptosis
2000
The 2.2 kb E1b mRNA of human Ad12 and Ad5 codes for two tumor antigens starting at different AUG triplets
1981
Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
1986 Standout
DNA Mismatch Repair:  Functions and Mechanisms
2005 StandoutNobel
DNA sequences from the adenovirus 2 genome.
1984 StandoutNobel
Cold-sensitive expression of transformation by a host range mutant of type 5 adenovirus.
1983
Aptamer-modified gold nanoparticles for targeting breast cancer cells through light scattering
2008
Control of adenovirus early gene expression: A class of immediate early products
1980
Complete transformation by adenovirus 2 requires both E1A proteins
1984
Multiple tachykinins are produced and secreted upon post-translational processing of the three substance P precursor proteins, α-, β-, and γ-preprotachykinin
1989 StandoutNobel
Adenovirus 2 lp+ locus codes for a 19 kd tumor antigen that plays an essential role in cell transformation
1983
Divergent transcription of early 35- and 94-kilodalton protein genes encoded by the HindIII K genome fragment of the baculovirus Autographa californica nuclear polyhedrosis virus
1987
Expression of adenovirus-2 early region 4: assignment of the early region 4 polypeptides to their respective mRNAs, using in vitro translation
1982
Adenoviruses of subgenera B, C, D, and E modulate cell-surface expression of major histocompatibility complex class I antigens.
1986 StandoutNobel
Monofunctionalized Gold Nanoparticles Stabilized by a Single Dendrimer Form Dumbbell Structures upon Homocoupling
2012 StandoutNobel
On the application potential of gold nanoparticles in nanoelectronics and biomedicine
2010
Transformation-defective mutant of adenovirus type 5 containing a single altered E1a mRNA species
1981
Association of adenovirus early-region 1A proteins with cellular polypeptides.
1986
Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein
2009
Characterization of the major mRNAs from adenovirus 2 early region 4 by cDNA cloning and sequencing
1984 StandoutNobel
Identification of human adenovirus early region 1 products by using antisera against synthetic peptides corresponding to the predicted carboxy termini
1983
A novel adenovirus-2 E1A mRNA encoding a protein with transcription activation properties.
1987
Peptide maps and N-terminal sequences of polypeptides from early region 1A of human adenovirus 5
1984
Mechanism of activation of early viral transcription by the adenovirus E1A gene product
1981
Restriction and modification in B. subtilis
1974
A short sequence in the COOH-terminus makes an adenovirus membrane glycoprotein a resident of the endoplasmic reticulum
1987 StandoutNobel
Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
2013 StandoutScience
Differential splicing yields novel adenovirus 5 E1A mRNAs that encode 30 kd and 35 kd proteins.
1987
A family of unusually spliced biologically active transcripts encoded by a Drosophila clock gene
1987 StandoutNatureNobel
Nudeotide sequence of the BsuRI restriction-modification system
1985 StandoutNobel
Cloning of a DNA fragment from the left-hand terminus of the adenovirus type 2 genome and its use in site-directed mutagenesis
1981
Deletion mutants of adenovirus 2: Isolation and initial characterization of virus carrying mutations near the right end of the viral genome
1981
The nucleotide sequence of the gene for protein IVa2 and of the 5' leader segment of the major late mRNAs of adenovirus type 5
1981
Intrinsic Structural Disorder in Adenovirus E1A: a Viral Molecular Hub Linking Multiple Diverse Processes
2008
Analysis of adenovirus transforming proteins from early regions 1A and 1B with antisera to inducible fusion antigens produced in Escherichia coli
1984
Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products
1985
The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product
1989 StandoutScience
Sequence analysis in the E1 region of adenovirus type 4 DNA
1986
The molecular structure of the 9 S mRNA from early region 1A of adenovirus serotype 2
1983
Regulation of Adenovirus Gene Expression
1982
Nucleotide sequences from the adenovirus-2 genome.
1982 StandoutNobel

Works of Helmut Esche being referenced

The Multifunctional Role of E1A in the Transcriptional Regulation of CREB/CBP-Dependent Target Genes
2003
Differences in the Interactions of Oncogenic Adenovirus 12 Early Region 1A and Nononcogenic Adenovirus 2 Early Region 1A with the Cellular Coactivators p300 and CBP
1999
Improved safety through tamoxifen-regulated induction of cytotoxic genes delivered by Ad vectors for cancer gene therapy
2000
Cellular Uptake and Toxicity of Au55 Clusters
2005
Regulation of Viral and Cellular Gene Expression by E1A Proteins Encoded by the Oncogenic Adenovirus Type 12
1995
Binding of PKA-RIIα to the Adenovirus E1A12S Oncoprotein Correlates with its Nuclear Translocation and an Increase in PKA-dependent Promoter Activity
2001
cAMP-independent Activation of the Adenovirus Type 12 E2 Promoter Correlates with the Recruitment of CREB-1/ATF-1, E1A12S, and CBP to the E2-CRE
2000
Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-κB and Myc/Max
1999
Identification of the Full-Length Huntingtin- Interacting Protein p231HBP/HYPB as a DNA-Binding Factor
2001
Repression of the c-Jun trans-Activation Function by the Adenovirus Type 12 E1A 52R Protein Correlates with the Inhibition of Phosphorylation of the c-Jun Activation Domain
1995
Amino acids 1–29 of the adenovirus serotypes 12 and 2 E1A proteins interact with rap30 (TFIIF) and TBP in vitro
1998
The histone acetyltransferase activity of PCAF cooperates with the brahma/SWI2-related protein BRG-1 in the activation of the enhancer A of the MHC class I promoter
2001
Expression of Early Viral Gene Products in Adenovirus Type 12-infected and -transformed cells
1982
Proteins and messenger RNAs of the transforming region of wild-type and mutant adenoviruses
1980
A multiprotein complex consisting of the cellular coactivator p300, AP-1/ATF, as well as NF-kappaB is responsible for the activation of the mouse major histocompatibility class I (H-2K(b)) enhancer A.
1999
Organization and Expression of the Left Third of the Genome of Adenovirus
1980
Asymmetric transcription of SPP1 in vivo
1973
Transactivation-deficient DeltaTA-p73 acts as an oncogene.
2002
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