Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization
2004 StandoutScienceNobel
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer
2005 StandoutNobel
Four-jointed Is a Golgi Kinase That Phosphorylates a Subset of Cadherin Domains
2008 Science
Circadian oscillation of nucleotide excision repair in mammalian brain
2009 StandoutNobel
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos
1995 Nature
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Par complex cluster formation mediated by phase separation
2020
Planar Polarity Specification through Asymmetric Subcellular Localization of Fat and Dachsous
2012
The Dynamics of Yeast Telomeres and Silencing Proteins through the Cell Cycle
2000
Four-Jointed Modulates Growth and Planar Polarity by Reducing the Affinity of Dachsous for Fat
2010
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Rb targets histone H3 methylation and HP1 to promoters
2001 Nature
Identification of in vivo DNA targets of chromatin proteins using tethered Dam methyltransferase
2000
Forces in Tissue Morphogenesis and Patterning
2013 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
PTEN Controls Junction Lengthening and Stability during Cell Rearrangement in Epithelial Tissue
2013
DNA methylation patterns and epigenetic memory
2002 Standout
Dissecting the Unique Role of the Retinoblastoma Tumor Suppressor during Cellular Senescence
2010
Sensing of Cytoskeletal Forces by Asymmetric Adherens Junctions
2017
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
2002
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
The Drosophila Circadian Network Is a Seasonal Timer
2007 StandoutNobel
Mechanisms of transcriptional memory
2001
A Screen for New Trithorax Group Genes Identified little imaginal discs, the Drosophila melanogaster Homologue of Human Retinoblastoma Binding Protein 2
2000
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Virus Infection Leads to Localized Hyperacetylation of Histones H3 and H4 at the IFN-β Promoter
1999
Establishment of Global Patterns of Planar Polarity during Growth of the Drosophila Wing Epithelium
2012
When Checkpoints Fail
1997 StandoutNobel
Propagation of Dachsous-Fat Planar Cell Polarity
2012
Patched acts catalytically to suppress the activity of Smoothened
2002 Nature
The hedgehog signaling network
2003
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog
2003
Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3
2016
Vertebrate Smoothened functions at the primary cilium
2005 StandoutNature
Regulation of Hormone-Induced Histone Hyperacetylation and Gene Activation via Acetylation of an Acetylase
1999
Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli
2005
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Differential Stabilization of Eukaryotic DNA Topoisomerase I Cleavable Complexes by Camptothecin Derivatives
1995 StandoutNobel
Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium of Drosophila
2010
Planar Cell Polarity Protein Celsr1 Regulates Endothelial Adherens Junctions and Directed Cell Rearrangements during Valve Morphogenesis
2013
Cockayne syndrome – a primary defect in DNA repair, transcription, both or neither?
1996
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation
2000 Nature
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Regulation of Frizzled by Fat-like Cadherins during Planar Polarity Signaling in the Drosophila Compound Eye
2002
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1999 StandoutNatureNobel
Modulation of Fat:Dachsous Binding by the Cadherin Domain Kinase Four-Jointed
2010
Cdk1-Dependent Phosphorylation of Cdc13 Coordinates Telomere Elongation during Cell-Cycle Progression
2009 StandoutNobel
C. elegans patched-3 is an essential gene implicated in osmoregulation and requiring an intact permease transporter domain
2011
Polycombing the Genome: PcG, trxG, and Chromatin Silencing
1998
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Hedgehog signaling in animal development: paradigms and principles
2001 Standout
The Polycomb group — no longer an exclusive club?
2001
Planar Cell Polarity: Coordinating Morphogenetic Cell Behaviors with Embryonic Polarity
2011
Switching and Signaling at the Telomere
2001 StandoutNobel
Cellular Determinants of Sensitivity and Resistance to DNA Topoisomerase Inhibitors
1994 StandoutNobel
Structural diversity of G protein-coupled receptors and significance for drug discovery
2008
Lithium Inhibits Glycogen Synthase Kinase-3 by Competition for Magnesium
2001
Chromatin immunoprecipitation and microarray-based analysis of protein location
2006
Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells
1996
Transcription — guarding the genome by sensing DNA damage
2004
CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin
1999
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Virus Infection Induces the Assembly of Coordinately Activated Transcription Factors on the IFN-β Enhancer In Vivo
1998
Stopped at the border: boundaries and insulators
1999
MEP-1 and a Homolog of the NURD Complex Component Mi-2 Act Together to Maintain Germline-Soma Distinctions in C. elegans
2002 StandoutNobel
Posttranslational Mechanisms Regulate the Mammalian Circadian Clock
2001
Signaling at zero G: G-protein-independent functions for 7-TM receptors
2001
Stimulation of c‐MYC transcriptional activity and acetylation by recruitment of the cofactor CBP
2003
A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3
2001 StandoutNobel
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes
1998
A molecular mechanism for the effect of lithium on development.
1996 Standout
DNA?protein crosslinks: their induction, repair, and biological consequences
2005
Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription
2000 StandoutNobel
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
2008 StandoutScienceNobel
Two-Step Cross-Linking Method for Identification of NF-κB Gene Network by Chromatin Immunoprecipitation
2005
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
2003 StandoutNobel
DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways.
1994
Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites.
1995 StandoutNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Tumor Cell Death Induced by Topoisomerase-Targeting Drugs
2001
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
2011 StandoutNobel
Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression inDrosophila
2006
Principles of planar polarity in animal development
2011
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression
1998 StandoutNobel
Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways fromDrosophilato vertebrates
2005
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos.
1995
Sonic Hedgehog Induces the Segregation of Patched and Smoothened in Endosomes
2002
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation
2018 StandoutNobel
Molecular Targets of Lithium Action
2001
Mechanical Control of Morphogenesis by Fat/Dachsous/Four-Jointed Planar Cell Polarity Pathway
2012 Science
Histone Acetylation Determines the Developmentally Regulated Accessibility for T Cell Receptor γ Gene Recombination
2001 StandoutNobel
PERIOD1-Associated Proteins Modulate the Negative Limb of the Mammalian Circadian Oscillator
2005 StandoutScienceNobel
Targeted Disruption of the Mouse Topoisomerase I Gene by Camptothecin Selection
1996 StandoutNobel
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
Repair of DNA–polypeptide crosslinks by human excision nuclease
2006 StandoutNobel
Cholesterol Sensing, Trafficking, and Esterification
2006
Cockayne syndrome group B protein enhances elongation by RNA polymerase II
1997 StandoutNobel
Works of Helen Strutt being referenced
Cleavage and secretion is not required for Four-jointed function in Drosophila patterning
2004
Differential Stability of Flamingo Protein Complexes Underlies the Establishment of Planar Polarity
2008
Differential activities of the core planar polarity proteins during Drosophila wing patterning
2006
Heritable Chromatin States Induced by the Polycomb and Trithorax Group Genes
2007
Co-localization of Polycomb protein and GAGA factor on regulatory elements responsible for the maintenance of homeotic gene expression
1997
Asymmetric localisation of planar polarity proteins: Mechanisms and consequences
2009
Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation
2001
Long‐range coordination of planar polarity in Drosophila
2005
Dynamics of Core Planar Polarity Protein Turnover and Stable Assembly into Discrete Membrane Subdomains
2011
Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila
2004
Glycogen synthase kinase 3 regulates cell fate in dictyostelium
1995
Polarity determination in the Drosophila eye
1999
Analysis of Chromatin Structure byin VivoFormaldehyde Cross-Linking
1997
Mapping DNA Target Sites of Chromatin Proteins In Vivo by Formaldehyde Crosslinking
2003
Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA
1991
Nonautonomous Planar Polarity Patterning in Drosophila
2002
The Frizzled-dependent planar polarity pathway locally promotes E-cadherin turnover via recruitment of RhoGEF2
2013
Strabismus is asymmetrically localised and binds to Prickle and Dishevelled duringDrosophilaplanar polarity patterning
2003
The Distribution of Polycomb-Group Proteins During Cell Division and Development in Drosophila Embryos: Impact on Models for Silencing
1998
The Polycomb Group Protein Complex of Drosophila melanogaster Has Different Compositions at Different Target Genes
1997
Hypersensitivity of Cockayne's syndrome cells to camptothecin is associated with the generation of abnormally high levels of double strand breaks in nascent DNA.
1993