Citation Impact
Citing Papers
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
Cancer–stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis
2012 StandoutNobel
Tight Control of Hypoxia-inducible Factor-α Transient Dynamics Is Essential for Cell Survival in Hypoxia
2014
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
2016 StandoutNobel
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
Roles of individual prolyl‐4‐hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice
2012 StandoutNobel
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
Role of platelet-derived growth factors in physiology and medicine
2008 Standout
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
Regulation of angiogenesis by oxygen sensing mechanisms
2009
Mitochondria: In Sickness and in Health
2012 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Regulation of tissue perfusion in mammals by hypoxia‐inducible factor 1
2007 StandoutNobel
Sustained expression of Hif‐1α in the diabetic environment promotes angiogenesis and cutaneous wound repair
2007
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets
2008
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
A hypoxic inducible factor‐1α hybrid enhances collateral development and reduces vascular leakage in diabetic rats
2009
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling
2010 StandoutNobel
Regulation of Vascularization by Hypoxia‐Inducible Factor 1
2009 StandoutNobel
Hypoxia-Induced Angiogenesis: Good and Evil
2011
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni
2017
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Inflammation in obesity, diabetes, and related disorders
2022 Standout
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
2008 Nature
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
2012 StandoutNobel
Oxygen homeostasis
2009 StandoutNobel
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
2012 Standout
Vascular Responses to Hypoxia and Ischemia
2009 StandoutNobel
Use of a Constitutively Active Hypoxia-Inducible Factor-1α Transgene as a Therapeutic Strategy in No-Option Critical Limb Ischemia Patients
2007
Effects of Aging and Hypoxia-Inducible Factor-1 Activity on Angiogenic Cell Mobilization and Recovery of Perfusion After Limb Ischemia
2007 StandoutNobel
Metabolic reprogramming by HIF-1 promotes the survival of bone marrow–derived angiogenic cells in ischemic tissue
2011 StandoutNobel
Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion
2014 StandoutNobel
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Hypoxia-Inducible Factor 1 and Cardiovascular Disease
2013 StandoutNobel
Peptide-matrix-mediated gene transfer of an oxygen-insensitive hypoxia-inducible factor-1α variant for local induction of angiogenesis
2006
Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively
2018 StandoutNobel
Prolyl 4‐hydroxylases, master regulators of the hypoxia response
2013
Virus-mediated gene transfer to induce therapeutic angiogenesis: where do we stand?
2007
Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation
2017 StandoutNobel
A Hypoxia-Induced Positive Feedback Loop Promotes Hypoxia-Inducible Factor 1α Stability through miR-210 Suppression of Glycerol-3-Phosphate Dehydrogenase 1-Like
2011
Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway
2015 StandoutNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
The Effect of Platelet-Derived Growth Factor Ligands in Rat Cardiac Allograft Vasculopathy and Fibrosis
2006
Essential Role for Prolyl Hydroxylase Domain Protein 2 in Oxygen Homeostasis of the Adult Vascular System
2007
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Works of Helder André being referenced
Identification of an Alternative Mechanism of Degradation of the Hypoxia-inducible Factor-1α
2008
Hypoxia-Inducible Factor-1α Is Associated With Sprouting Angiogenesis in the Murine Laser-Induced Choroidal Neovascularization Model
2015
Stabilized HIF‐1α is superior to VEGF for angiogenesis in skeletal muscle via adeno‐associated virus gene transfer
2005