Citation Impact
Citing Papers
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models
2006 Science
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Colonic bacterial composition in Parkinson's disease
2015 Standout
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
2015 StandoutNobel
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED
2015 StandoutNobel
The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementia
2010
Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein
2013
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
The Role of Autophagy in Parkinson's Disease
2012
Clearance of α-Synuclein Oligomeric Intermediates via the Lysosomal Degradation Pathway
2004
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans
2010
Origins and Effects of Extracellular α-synuclein: Implications in Parkinson’s Disease
2007
The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids
2009
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases
2016
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells
2016
Glucocerebrosidase is shaking up the synucleinopathies
2014
Pathogenic protein seeding in alzheimer disease and other neurodegenerative disorders
2011
Radical medicine: treating ageing to cure disease
2005
Imaging in the era of molecular oncology
2008 StandoutNature
Neurochemistry and the non-motor aspects of PD
2011
A century-old debate on protein aggregation and neurodegeneration enters the clinic
2006 Nature
Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
2013 Nature
Accumulation of Toxic α-Synuclein Oligomer within Endoplasmic Reticulum Occurs in α-SynucleinopathyIn Vivo
2012
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology
2008 Standout
Exosomes in the Pathology of Neurodegenerative Diseases
2016
Fluorescence imaging of amyloid formation in living cells by a functional, tetracysteine-tagged α-synuclein
2007
Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives
2014
Spreading of pathology in neurodegenerative diseases: a focus on human studies
2015
Mitochondrial Dysfunction and Neurodegeneration in Lysosomal Storage Disorders
2017
The Co-chaperone Carboxyl Terminus of Hsp70-interacting Protein (CHIP) Mediates α-Synuclein Degradation Decisions between Proteasomal and Lysosomal Pathways
2005
Genetic Animal Models of Parkinson's Disease
2010
Part II: α-synuclein and its molecular pathophysiological role in neurodegenerative disease
2003
α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
2011
Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of γ‐synuclein, α‐synuclein and double α/γ‐synuclein null mutant mice
2004
Development of α-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson’s disease
2007
The prion hypothesis in Parkinson's disease: Braak to the future
2013
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
100 years of Lewy pathology
2012
A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP
2013
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
2006 StandoutNature
Prion-like transmission of protein aggregates in neurodegenerative diseases
2010
Decoding ALS: from genes to mechanism
2016 StandoutNature
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
On the mechanism of internalization of α‐synuclein into microglia: roles of ganglioside GM1 and lipid raft
2009
The executioners sing a new song: killer caspases activate microglia
2011
Proteasomal Inhibition-Induced Inclusion Formation and Death in Cortical Neurons Require Transcription and Ubiquitination
2002
Parkinson's disease
2015 Standout
Protein folding and misfolding
2003 StandoutNature
Distinct Region-Specific α-Synuclein Oligomers in A53T Transgenic Mice: Implications for Neurodegeneration
2010
Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies
2013
Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP111-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
2003
Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies
2015
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Oxidative stress in Parkinson's disease
2003 Standout
Pathogenesis of parkinson's disease: dopamine, vesicles and α-synuclein
2002
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Autophagy in Human Health and Disease
2013 Standout
Parkin Protects against the Toxicity Associated with Mutant α-Synuclein
2002
Immunological features of α‐synuclein in Parkinson's disease
2008
Parkinson's disease and α‐synuclein expression
2011
The propagation of prion-like protein inclusions in neurodegenerative diseases
2010
Structure/function of α‐synuclein in health and disease: rational development of animal models for Parkinson's and related diseases
2002
Hassles with Taking Out the Garbage: Aggravating Aggresomes
2002
Basic mechanisms of neurodegeneration: a critical update
2010
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
Non-motor features of Parkinson disease
2017 Standout
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
2012
α-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy body disease
2016
The Amyloid State of Proteins in Human Diseases
2012 Standout
Accelerating progress in induced pluripotent stem cell research for neurological diseases
2012
Molecular and clinical prodrome of Parkinson disease: implications for treatment
2010
Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice
2012
Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
2014
Genetics of Parkinson's disease and biochemical studies of implicated gene products: Commentary
2002
α-Synuclein expression in HEK293 cells enhances the mitochondrial sensitivity to rotenone
2003
Neuroinflammation and Oxidation/Nitration of α-Synuclein Linked to Dopaminergic Neurodegeneration
2008
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Systematic Mutagenesis of α-Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities
2012 StandoutNobel
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
2014
Prion-like spreading of pathological α-synuclein in brain
2013
Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts
2011
Neuronal degeneration and mitochondrial dysfunction
2003
Genetics of Parkinson's disease and biochemical studies of implicated gene products
2002
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
2006 Standout
Aggresomes Formed by α-Synuclein and Synphilin-1 Are Cytoprotective
2004
Linking pathways in the developing and aging brain with neurodegeneration
2014
Glia and alpha-synuclein in neurodegeneration: A complex interaction
2015
The Hallmarks of Aging
2013 Standout
Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders
2010
The new mutation, E46K, of α‐synuclein causes parkinson and Lewy body dementia
2003 Standout
Neurodegeneration and neuroprotection in Parkinson disease
2004
Glucocerebrosidase and Parkinson disease: Recent advances
2015
Exosomes, an Unmasked Culprit in Neurodegenerative Diseases
2017
Parkinson's Disease
2003 Standout
Pathogenesis of Parkinson disease—the gut–brain axis and environmental factors
2015
Different Species of α-Synuclein Oligomers Induce Calcium Influx and Seeding
2007
The Deacetylase HDAC6 Regulates Aggresome Formation and Cell Viability in Response to Misfolded Protein Stress
2003 Standout
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine
2005 Standout
Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease
2011
AnIn VitroModel of Parkinson's Disease: Linking Mitochondrial Impairment to Altered α-Synuclein Metabolism and Oxidative Damage
2002
Neuroimmunological Processes in Parkinson’s Disease and their Relation to α-Synuclein: Microglia as the Referee between Neuronal Processes and Peripheral Immunity
2013
PROTOFIBRILS , PORES , FIBRILS, AND NEURODEGENERATION : Separating the Responsible Protein Aggregates from The Innocent Bystanders
2003
Combination therapies: The next logical Step for the treatment of synucleinopathies?
2015
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Do prions cause Parkinson disease?: The evidence accumulates
2014
Anti‐tau antibody reduces insoluble tau and decreases brain atrophy
2015
Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade
2018
Ion-dependent protein–surface interactions from intrinsic solvent response
2021 StandoutNobel
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
2012
The Parkinson’s disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking
2016
Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation
2010
Double-knockout mice for α- and β-synucleins: Effect on synaptic functions
2004 StandoutNobel
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Lewy body extracts from Parkinson disease brains trigger α‐synuclein pathology and neurodegeneration in mice and monkeys
2013
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Zeroing in on the Pathogenic Form of α-Synuclein and Its Mechanism of Neurotoxicity in Parkinson's Disease
2003
Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
2004 StandoutScience
Mechanism of Toxicity in Rotenone Models of Parkinson's Disease
2003
Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice
2004
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
2013
Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells
2011
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
Genes associated with Parkinson's disease: regulation of autophagy and beyond
2015
Neuronal degeneration and mitochondrial dysfunction
2003
Self-catalyzed growth of S layers via an amorphous-to-crystalline transition limited by folding kinetics
2010 StandoutNobel
Nondestructive nanostraw intracellular sampling for longitudinal cell monitoring
2017
Alzheimer’s and Parkinson’s diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein
2015 Science
Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative Stress
2020
Neuronal activity regulates extracellular tau in vivo
2014
α‐Synuclein oligomers and clinical implications for Parkinson disease
2012
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of He-Jin Lee being referenced
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein
2009
Dopamine promotes formation and secretion of non-fibrillar alpha-synuclein oligomers
2011
Autophagic failure promotes the exocytosis and intercellular transfer of α-synuclein
2013
Stabilization of Partially Folded Conformation during α-Synuclein Oligomerization in Both Purified and Cytosolic Preparations
2001
Cell-to-Cell Transmission of α-Synuclein Aggregates
2012
Enzyme-linked immunosorbent assays for alpha-synuclein with species and multimeric state specificities
2011
Formation and Removal of α-Synuclein Aggregates in Cells Exposed to Mitochondrial Inhibitors
2002
Intravesicular Localization and Exocytosis of α-Synuclein and its Aggregates
2005
Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies
2010
Characterization of Cytoplasmic α-Synuclein Aggregates
2002
Protein aggregate spreading in neurodegenerative diseases: Problems and perspectives
2011
Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia
2013
Glucocerebrosidase depletion enhances cell-to-cell transmission of α-synuclein
2014
Assembly-dependent endocytosis and clearance of extracellular a-synuclein
2008
Loss of glucocerebrosidase 1 activity causes lysosomal dysfunction and α-synuclein aggregation
2015
Golgi Fragmentation Occurs in the Cells with Prefibrillar α-Synuclein Aggregates and Precedes the Formation of Fibrillar Inclusion
2002
Clearance and deposition of extracellular α-synuclein aggregates in microglia
2008