Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Deep Brain Stimulation for Treatment-Resistant Depression
2005 Standout
Lithium’s Emerging Role in the Treatment of Refractory Major Depressive Episodes: Augmentation of Antidepressants
2010
Stress Hormone-Related Psychopathology: Pathophysiological and Treatment Implications
2001
Sleep and mental disorders: A meta-analysis of polysomnographic research.
2016
A Meta-Analysis of Cytokines in Major Depression
2009 Standout
Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for Difficult-to-Treat depression
2003
World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 1: Acute and Continuation Treatment of Major Depressive Disorder
2002
Major Depressive Disorder
2000
Acute and Longer-Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps: A STAR*D Report
2006 Standout
The Dexamethasone/Corticotropin-Releasing Factor Test in Men with Major Depression: Role of Childhood Trauma
2007
Hypothalamo-pituitary-adrenal function in patients with depressive disorders is correlated with baseline cytokine levels, but not with cytokine responses to hydrocortisone
2003
Cortisol response in the combined dexamethasone/CRH test as predictor of relapse in patients with remitted depression
2001
Rapid recovery from major depression using magnesium treatment
2006
Pro-inflammatory cytokines and treatment response to escitaloprsam in major depressive disorder
2007
Depression
2018 Standout
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.
2014 Standout
Serotonin and neuroplasticity – Links between molecular, functional and structural pathophysiology in depression
2017
Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression
2009 Standout
Polymorphisms of the Glucocorticoid Receptor Gene and Major Depression
2006
Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders
2015
Metyrapone as Additive Treatment in Major Depression
2004
The Corticosteroid Receptor Hypothesis of Depression
2000 Standout
Child abuse: Adolescent records vs. adult recall
1990 Standout
Antiglucocorticoid drugs in the treatment of depression
2001
Corticotropin-Releasing Factor in Brain: A Role in Activation, Arousal, and Affect Regulation
2004
DST non-suppression predicts suicide after attempted suicide
2007
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
2009 Standout
Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors
2005
Drug-Dependent Requirement of Hippocampal Neurogenesis in a Model of Depression and of Antidepressant Reversal
2008
Angiotensin-Converting Enzyme Polymorphism and Completed Suicide: An Association in Caucasians and Evidence for a Link with a Method of Self-Injury
2009
(Far) Outside the box: Genomic approach to acute porphyria
2006
Neural regulation of endocrine and autonomic stress responses
2009 Standout
Treatment of mood disorders
2002
Novel Drugs and Therapeutic Targets for Severe Mood Disorders
2008
Overexpressing the Glucocorticoid Receptor in Forebrain Causes an Aging-Like Neuroendocrine Phenotype and Mild Cognitive Dysfunction
2007
Cognitive and serotonergic vulnerability to depression: Convergent findings.
2007
Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
2007 Standout
The link between childhood trauma and depression: Insights from HPA axis studies in humans
2008
Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: Comorbidity between depression and neurodegenerative disorders
2008
When brain clocks lose track of time: cause or consequence of neuropsychiatric disorders
2011 StandoutNobel
The Flinders Sensitive Line rat: A selectively bred putative animal model of depression
2005
Increased soluble tumor necrosis factor‐α receptors in patients with major depressive disorder
2009
Suppression of the MEK/ERK Signaling Pathway Reverses Depression-like Behaviors of CRF2-Deficient Mice
2008
CRF system and mood disorders
2013
Effects of stress throughout the lifespan on the brain, behaviour and cognition
2009 Standout
Porphyrias
2010 Standout
Younger, premenopausal women with major depressive disorder have more abdominal fat and increased serum levels of prothrombotic factors: implications for greater cardiovascular risk
2005
Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress
2003
Dysregulated relationship of inflammation and oxidative stress in major depression
2012
Life’s Essential 8: Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association
2022 Standout
Depression, comorbidities and the TNF-α system
2008
Linking “big” personality traits to anxiety, depressive, and substance use disorders: A meta-analysis.
2010 Standout
Candidate Genes Expression Profile Associated with Antidepressants Response in the GENDEP Study: Differentiating between Baseline ‘Predictors’ and Longitudinal ‘Targets’
2012
Future Suicide Attempt and Responses to Serotonergic Challenge
2008
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
The CRF system, stress, depression and anxiety—insights from human genetic studies
2009
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Acute Stressors and Cortisol Responses: A Theoretical Integration and Synthesis of Laboratory Research.
2004 Standout
PRECLINICAL STUDY: Corticotropin‐releasing factor‐1 receptor antagonists decrease heroin self‐administration in long‐ but not short‐access rats
2009
New approaches to antidepressant drug discovery: beyond monoamines
2006
Risk factors for suicidal thoughts and behaviors: A meta-analysis of 50 years of research.
2016 Standout
Buprenorphine and a CRF1 Antagonist Block the Acquisition of Opiate Withdrawal-Induced Conditioned Place Aversion in Rats
2004
Pituitary-Adrenal and Autonomic Responses to Stress in Women After Sexual and Physical Abuse in Childhood
2000
Facial shape differences between rats selected for tame and aggressive behaviors
2017 StandoutNobel
Stress and the brain: from adaptation to disease
2005 Standout
Neuropeptide Y (NPY) shortens sleep latency but does not suppress ACTH and cortisol in depressed patients and normal controls
2005
Power failure: why small sample size undermines the reliability of neuroscience
2013 Standout
Corticosteroids in relation to fear, anxiety and psychopathology
2001
Neurobiology of Depression
2002 Standout
Discovering Endophenotypes for Major Depression
2004
How can we realize the promise of personalized antidepressant medicines?
2008
Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis
2009 Standout
Major Depressive Disorder
2008 Standout
Hypothalamic–Pituitary–Adrenal Axis Activity and Sleep in Posttraumatic Stress Disorder
2005
Sleep deprivation in depression
2010
CSF 5-HIAA and DST non-suppression — Orthogonal biologic risk factors for suicide in male mood disorder inpatients
2008
Development of pharmacotherapies for drug addiction: a Rosetta Stone approach
2009
The interpersonal theory of suicide.
2010 Standout
AGA technical review on irritable bowel syndrome
2002 Standout
Non-specific low back pain
2011 Standout
The role of immune genes in the association between depression and inflammation: A review of recent clinical studies
2012
Early life stress as a risk factor for mental health: Role of neurotrophins from rodents to non-human primates
2008
Glucocorticoid antagonists in neuropsychotic disorders
2008
Salivary cortisol in depressed patients versus control persons: A systematic review and meta-analysis
2010
From inflammation to sickness and depression: when the immune system subjugates the brain
2007 Standout
The Role of TNF-α in Patients With Chronic Low Back Pain—A Prospective Comparative Longitudinal Study
2008
The tail suspension test as a model for assessing antidepressant activity: Review of pharmacological and genetic studies in mice
2005
Effects of the monoamine oxidase A inhibitor moclobemide on hippocampal plasticity in GR-impaired transgenic mice
2001
If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans.
2007 Standout
Molecular biomarkers of depression
2016
The molecular neurobiology of depression
2008 StandoutNature
Neurocircuitry of Addiction
2009 Standout
The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies
2001 Standout
Neuroscience, Molecular Biology, and the Childhood Roots of Health Disparities
2009 Standout
Therapeutic potential of CRF receptor antagonists: a gut-brain perspective
2001
The Effect of Antidepressant Medication Treatment on Serum Levels of Inflammatory Cytokines: A Meta-Analysis
2011
A Resource of Cre Driver Lines for Genetic Targeting of GABAergic Neurons in Cerebral Cortex
2011 Standout
Research and treatment approaches to depression
2001
Neuroendocrine aspects of the response to stress
2002
The role of inflammation in depression: from evolutionary imperative to modern treatment target
2015 Standout
Low plasma BDNF is associated with suicidal behavior in major depression
2006
Can Meditation Slow Rate of Cellular Aging? Cognitive Stress, Mindfulness, and Telomeres
2009 StandoutNobel
The neurobiology of depression and antidepressant action
2012
Cytokine-effects on glucocorticoid receptor function: Relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression
2006
Magnesium in Man: Implications for Health and Disease
2014 Standout
A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis
2012 StandoutNobel
Angst and the amygdala
2006
The circadian basis of winter depression
2006
III. Stress-related alterations of gut motor function: role of brain corticotropin-releasing factor receptors
2001
Stress, hypercortisolism and corticosteroid receptors in depression: implicatons for therapy
2001
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
About Sleep's Role in Memory
2013 Standout
Risky families: Family social environments and the mental and physical health of offspring.
2002 Standout
Stress Hormone Regulation: Biological Role and Translation into Therapy
2009
Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants
2003 StandoutScience
The Prevalence of Comorbid Depression in Adults With Diabetes
2001 Standout
Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
2013
The neurobiology of depression: inroads to treatment and new drug discovery.
2005
CRF and CRF Receptors: Role in Stress Responsivity and Other Behaviors
2004
Works of Heike Künzel being referenced
Combined Dexamethasone/Corticotropin Releasing Hormone Test Predicts Treatment Response in Major Depression–A Potential Biomarker?
2006
Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated
2000
Treatment of depression with the CRH-1-receptor antagonist R121919: endocrine changes and side effects
2003
State Markers of Depression in Sleep EEG: Dependency on Drug and Gender in Patients Treated with Tianeptine or Paroxetine
2003
Hypothalamus-pituitary-adrenal system regulation and suicidal behavior in depression
2005
High-Affinity CRF1 Receptor Antagonist NBI-34041: Preclinical and Clinical Data Suggest Safety and Efficacy in Attenuating Elevated Stress Response
2007
Pharmacological and Nonpharmacological Factors Influencing Hypothalamic–Pituitary–Adrenocortical Axis Reactivity in Acutely Depressed Psychiatric In-patients, Measured by the Dex-CRH Test
2003
The combined dexamethasone/CRH test as a potential surrogate marker in depression
2005
Changes in the Hypothalamic-Pituitary-Adrenal Axis and Leptin Levels during Antidepressant Treatment
2007
Association between response to lithium augmentation and the combined DEX/CRH test in major depressive disorder
2003
Oral Mg2+ Supplementation Reverses Age-Related Neuroendocrine and Sleep EEG Changes in Humans
2002
The Renin-Angiotensin-Aldosterone system in patients with depression compared to controls – a sleep endocrine study
2003
Renin-Angiotensin-Aldosterone System, HPA-Axis and Sleep-EEG Changes in Unmedicated Patients with Depression after Total Sleep Deprivation
2006
Increased nocturnal secretion of ACTH and cortisol in obsessive compulsive disorder
2006
Treatment with the CRH1-receptor-antagonist R121919 improves sleep-EEG in patients with depression
2003
Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders
2004
Outcome in delusional depression comparing trimipramine monotherapy with a combination of amitriptyline and haloperidol – A double-blind multicenter trial
2008
Successful Antidepressant Therapy Restores the Disturbed Interplay Between TNF-α System and HPA Axis
2006
HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients
2008