Citation Impact
Citing Papers
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Mechanism of auxin perception by the TIR1 ubiquitin ligase
2007 Nature
Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle
2023 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Intramolecular Control of Protein Stability, Subnuclear Compartmentalization, and Coactivator Function of Peroxisome Proliferator-activated Receptor γ Coactivator 1α
2007
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Mammalian Fe–S cluster biogenesis and its implication in disease
2014
A two stage click-based library of protein tyrosine phosphatase inhibitors
2006
Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production
2008 Standout
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
RNA Binding-independent Dimerization of Adenosine Deaminases Acting on RNA and Dominant Negative Effects of Nonfunctional Subunits on Dimer Functions
2007
Structural insight into the PTS sugar transporter EIIC
2014
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
Mechanism of Ubiquitin-Chain Formation by the Human Anaphase-Promoting Complex
2008
The type III needle and the damage done
2005
Nickel uptake and utilization by microorganisms
2003
The Glutamine Residue of the Conserved GGQ Motif in Saccharomyces cerevisiae Release Factor eRF1 Is Methylated by the Product of the YDR140w Gene
2004
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Membrane budding and scission by the ESCRT machinery: it's all in the neck
2010
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
A Genomic and Functional Inventory of Deubiquitinating Enzymes
2005 Standout
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
Solution Structure of the Ubp-M BUZ Domain, a Highly Specific Protein Module that Recognizes the C-terminal Tail of Free Ubiquitin
2007
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Recognition and specificity in protein tyrosine kinase-mediated signalling
1995
A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination
2006
Pore loops: An emerging theme in ion channel structure
1995 StandoutNobel
Comparative genomic analyses of nickel, cobalt and vitamin B12 utilization
2009
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Structure, mechanism, and evolution of the mRNA capping apparatus
2000
Sequential E2s Drive Polyubiquitin Chain Assembly on APC Targets
2007
Structure of a Cell Polarity Regulator, a Complex between Atypical PKC and Par6 PB1 Domains
2004
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells
2012 Nature
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Molecular Basis for Bacterial Class I Release Factor Methylation by PrmC
2005
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Iron–sulfur cluster biogenesis and human disease
2008
ECOD: An Evolutionary Classification of Protein Domains
2014
Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
2006
Multimodal Activation of the Ubiquitin Ligase SCF by Nedd8 Conjugation
2008
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
RF3 Induces Ribosomal Conformational Changes Responsible for Dissociation of Class I Release Factors
2007 StandoutNobel
A Red Carpet for Iron Metabolism
2017
Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity
2016
The biological occurrence and trafficking of cobalt
2011
Basis for a ubiquitin-like protein thioester switch toggling E1–E2 affinity
2007 Nature
Crystal Structure of the Ubiquitin Binding Domains of Rabex-5 Reveals Two Modes of Interaction with Ubiquitin
2006
The bacterial injection kit: Type III secretion systems
2005
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon
2005 StandoutNobel
Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion
2007 StandoutNobel
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Ubiquitin and ubiquitin-like proteins as multifunctional signals
2005
Evaluation of a Diffusion-Driven Mechanism for Substrate Ubiquitination by the SCF-Cdc34 Ubiquitin Ligase Complex
2006
A ubiquitin-interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome
2006
The ESCRT Pathway
2011
Structural Basis for Recruitment of Ubc12 by an E2 Binding Domain in NEDD8's E1
2005
A ubiquitin ligase complex assembles linear polyubiquitin chains
2006
Selenium incorporation using recombinant techniques
2010
Energetics of nucleophile activation in a protein tyrosine phosphatase
1997
Diverse polyubiquitin interaction properties of ubiquitin-associated domains
2005
Function and biogenesis of iron–sulphur proteins
2009 Nature
Mitochondrial Mayhem: The Mitochondrion as a Modulator of Iron Metabolism and Its Role in Disease
2011
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Prediction of the structure of symmetrical protein assemblies
2007 StandoutNobel
Functions and Regulation of RNA Editing by ADAR Deaminases
2010
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Is the PTPase−Vanadate Complex a True Transition State Analogue?
2002
Human ESCRT-II Complex and Its Role in Human Immunodeficiency Virus Type 1 Release
2006
SUMO junction—what's your function?
2007
Protein Analysis by Shotgun/Bottom-up Proteomics
2013
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Recognition Dynamics Up to Microseconds Revealed from an RDC-Derived Ubiquitin Ensemble in Solution
2008 Science
Cell Signaling in Space and Time: Where Proteins Come Together and When They’re Apart
2009 Science
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain
1997
Crystal Structure of the PTEN Tumor Suppressor
1999
RING Domain E3 Ubiquitin Ligases
2009 Standout
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
1997
E-Syts, a family of membranous Ca 2+ -sensor proteins with multiple C 2 domains
2007 StandoutNobel
Walden-Inversion-Enforced Transition-State Stabilization in a Protein Tyrosine Phosphatase
1998
Crystal Structure of the Dual Specificity Protein Phosphatase VHR
1996 Science
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Dissecting the catalytic mechanism of protein-tyrosinephosphatases.
1994
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
The Role of Dynamics in Enzyme Activity
2003
Enzyme millisecond conformational dynamics do not catalyze the chemical step
2009 StandoutNobel
Structural Mechanisms Underlying Posttranslational Modification by Ubiquitin-Like Proteins
2007
Functional dynamics in the active site of the ribonuclease binase
2001
Mechanisms of signaling and related enzymes
1997
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
Mechanisms of signaling and related enzymes
1997
Analysis of iron–sulfur protein maturation in eukaryotes
2009
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Chemical Glycoproteomics
2016 StandoutNobel
Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis.
1996
YERSINIA OUTER PROTEINS: Role in Modulation of Host Cell Signaling Responses and Pathogenesis
2005
Works of Heidi Schubert being referenced
Inositol Hexakisphosphate Is Bound in the ADAR2 Core and Required for RNA Editing
2005 Science
Structures along the Catalytic Pathway of PrmC/HemK, an N 5 -Glutamine AdoMet-Dependent Methyltransferase
2003
Ubiquitin-binding domains
2005
Ubiquitin Recognition by the Human TSG101 Protein
2004
Deficiency of glutaredoxin 5 reveals Fe–S clusters are required for vertebrate haem synthesis
2005 Nature
The Cys(X)5Arg Catalytic Motif in Phosphoester Hydrolysis
1994
The X-ray Crystal Structures of Yersinia Tyrosine Phosphatase with Bound Tungstate and Nitrate
1996
The biosynthesis of adenosylcobalamin (vitamin B12)
2002
Biosynthesis of cobalamin (vitamin B12): a bacterial conundrum
2000
Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 Å and the complex with tungstate
1994 Nature
Many paths to methyltransfer: a chronicle of convergence
2003
Structural basis for ESCRT-III protein autoinhibition
2009
A ligand-induced conformational change in theyersiniaprotein tyrosine phosphatase
1995
Two substrate‐targeting sites in the Yersinia protein tyrosine phosphatase co‐operate to promote bacterial virulence
2005
Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase.
1992
Identification and functional analysis of enzymes required for precorrin-2 dehydrogenation and metal ion insertion in the biosynthesis of sirohaem and cobalamin in Bacillus megaterium
2003