Citation Impact
Citing Papers
Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase
2004 StandoutScience
Requirement of NAD and SIR2 for Life-Span Extension by Calorie Restriction in Saccharomyces cerevisiae
2000 StandoutScience
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
2004 StandoutScience
Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance
1996
The DNA-damage response in human biology and disease
2009 StandoutNature
The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku
2001
Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family
1997
ATM-related genes: What do they tell us about functions of the human gene?
1995
A systematic RNAi screen for longevity genes in C. elegans
2005 StandoutNobel
DNA Damage-Induced Phosphorylation of p53 Alleviates Inhibition by MDM2
1997 Standout
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
Multiple signalling pathways trigger the exquisite sensitivity of yeast gluconeogenic mRNAs to glucose
1996
Relocalization of Telomeric Ku and SIR Proteins in Response to DNA Strand Breaks in Yeast
1999
Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae
2000
Structural Insights into Yeast Telomerase Recruitment to Telomeres
2017
When Checkpoints Fail
1997 StandoutNobel
Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action
2002 Standout
Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors
2005 Standout
Telomere Dysfunction Increases Mutation Rate and Genomic Instability
2001 StandoutNobel
Yeast DNA ligase IV mediates non-homologous DNA end joining
1997 Nature
Telomere dysfunction and the initiation of genome instability
2003 StandoutNobel
Functional links between telomeres and proteins of the DNA-damage response
2004
Mutually Exclusive Binding of Telomerase RNA and DNA by Ku Alters Telomerase Recruitment Model
2012 Nobel
Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm
2000 StandoutNobel
Secondary Structure of Vertebrate Telomerase RNA
2000 StandoutNobel
EXO1 -dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70 Δ mutants
2002
A bulged stem tethers Est1p to telomerase RNA in budding yeast
2002 StandoutNobel
MEC1-Dependent Redistribution of the Sir3 Silencing Protein from Telomeres to DNA Double-Strand Breaks
1999
5 DNA Breakage and Repair
1998
Nuclear pore complexes in the organization of silent telomeric chromatin
2000 Nature
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
2001 StandoutNature
Cdk1-Dependent Phosphorylation of Cdc13 Coordinates Telomere Elongation during Cell-Cycle Progression
2009 StandoutNobel
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
2000 StandoutNature
Switching and Signaling at the Telomere
2001 StandoutNobel
Saccharomyces Ku70, Mre11/Rad50, and RPA Proteins Regulate Adaptation to G2/M Arrest after DNA Damage
1998
Absence of p350 Subunit of DNA-Activated Protein Kinase from a Radiosensitive Human Cell Line
1995 Science
A newly identified DNA ligase of Saccharomyces cerevisiaeinvolved in RAD52-independent repair of DNA double-strand breaks
1997 StandoutNobel
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
2004 StandoutNature
Interactions between subunits of the Mediator complex with gene-specific transcription factors
2011
Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70
2002
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
2001 StandoutNobel
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
1999 Standout
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
1998
The Hallmarks of Aging
2013 Standout
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
2005 StandoutNature
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair
1997
The DNA-dependent protein kinase
1999
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
2004 StandoutNature
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae
1997 Nature
Dissecting the Regulatory Circuitry of a Eukaryotic Genome
1998 Standout
The DNA-binding Protein Hdf1p (a Putative Ku Homologue) Is Required for Maintaining Normal Telomere Length in Saccharomyces Cerevisiae
1996
hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase
2001 Standout
Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
1998
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
Tetrahymena proteins p80 and p95 are not core telomerase components
2001 StandoutNobel
Telomerase core components protect Candida telomeres from aberrant overhang accumulation
2007 StandoutNobel
Rap1 protein regulates telomere turnover in yeast
1998 StandoutNobel
Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways.
1996
DNA double-strand-break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiae
1997
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
2006 StandoutNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Identification of Genes Involved in Repair of DNA Double-Strand Breaks in Mammalian Cells
1998
Life with 6000 Genes
1996 StandoutScience
Ku is associated with the telomere in mammals
1999 StandoutNobel
Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale
1997 StandoutScience
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
Telomere fusions caused by mutating the terminal region of telomeric DNA
2000 StandoutNobel
Varying the number of telomere-bound proteins does not alter telomere length in tel1Δ cells
1999
Functional Interplay of the Mre11 Nuclease and Ku in the Response to Replication-Associated DNA Damage
2011
DNA end-joining: from yeast to man
1998
Distinct roles of yeast MEC and RAD checkpoint genes in transcriptional induction after DNA damage and implications for function.
1996
DNA Double-Strand Breaks
2002 StandoutNobel
DNA end-joining catalyzed by human cell-free extracts
1998
STRUCTURE, FUNCTION, AND REPLICATION OF SACCHAROMYCES CEREVISIAE TELOMERES
1996
Protection of Telomeres by the Ku Protein in Fission Yeast
2000 Nobel
Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage
1998 StandoutScience
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Characterization of a mutant strain of Saccharomyces cerevisiae with a deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene
1995
Cell Cycle Checkpoints: Preventing an Identity Crisis
1996 StandoutScience
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Repair of Intermediate Structures Produced at DNA Interstrand Cross-Links in Saccharomyces cerevisiae
2000
DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair.
1995
Works of Heidi Feldmann being referenced
A Short C-terminal Domain of Yku70p Is Essential for Telomere Maintenance
2000
Involvement of the Saccharomyces cerevisiae HDF1 Gene in DNA Double-strand Break Repair and Recombination
1996
Nucleotide sequence of the phosphoenolpyruvate carboxykinase gene from Saccharomyces cerevisiae
1988
Separation-of-function Mutants of Yeast Ku80 Reveal a Yku80p-Sir4p Interaction Involved in Telomeric Silencing
2003
Structure–system correlation identifies a gene regulatory Mediator submodule
2008
HDF2, the Second Subunit of the Ku Homologue from Saccharomyces cerevisiae
1996
A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae
1993