Citation Impact
Citing Papers
Melatonin Suppresses Nighttime Memory Formation in Zebrafish
2007 Science
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
Whole-genome resequencing reveals loci under selection during chicken domestication
2010 StandoutNature
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
2006
Cryptochrome, Circadian Cycle, Cell Cycle Checkpoints, and Cancer
2005 StandoutNobel
Interaction of melatonin with human lymphocytes: Evidence for binding sites coupled to potentiation of cyclic AMP stimulated by vasoactive intestinal peptide and activation of cyclic GMP
1992
Melatonin inhibits hippocampal long‐term potentiation
2005
The cholinergic hypothesis of Alzheimer's disease: a review of progress
1999 Standout
Expression of membrane and nuclear melatonin receptors in mouse peripheral organs
2004
Review of Pharmacological Treatment in Mood Disorders and Future Directions for Drug Development
2011
Projections of the suprachiasmatic nuclei, subparaventricular zone and retrochiasmatic area in the golden hamster
1994
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Identification of the Melatonin-binding SiteMT 3 as the Quinone Reductase 2
2000
The significance of the metabolism of the neurohormone melatonin: Antioxidative protection and formation of bioactive substances
1993 Standout
Agomelatine(S 20098) antagonizes the penile erections induced by the stimulation of 5-HT 2C receptors in Wistar rats
2003
The Physiology and Pharmacology of Melatonin in Humans
1998
Melatonin receptor mRNA expression in human granulosa cells
1999
Network pharmacology: the next paradigm in drug discovery
2008 Standout
Melatonin synthesis and melatonin‐membrane receptor (MT1) expression during rat thymus development: role of the pineal gland
2005
Effects of Aging and Melatonin Administration on Gonadotropin-Releasing Hormones (GnRH) Gene Expression in the Male and Female Rat
1997
Effect of melatonin on chloride secretion by human colonic T84 cells
1998
REVIEW ON CPP: Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade
2007 Standout
Sleep Patterns and Predictors of Disturbed Sleep in a Large Population of College Students
2009 Standout
Bioluminescence and chemiluminescence in drug screening
2003
Mapping the Melatonin Receptor. 6. Melatonin Agonists and Antagonists Derived from 6H-Isoindolo[2,1-a]indoles, 5,6-Dihydroindolo[2,1-a]isoquinolines, and 6,7-Dihydro-5H-benzo[c]azepino[2,1-a]indoles
2000
Ancestral TSH Mechanism Signals Summer in a Photoperiodic Mammal
2008
Melatonin suppresses the induction of AP-1 transcription factor components in the pars tuberalis of the pituitary
1996
Catalytic Functionalization of Indoles in a New Dimension
2009 Standout
Drug-like properties and the causes of poor solubility and poor permeability
2000 Standout
Variable cytocompatibility of six cell lines with photoinitiators used for polymerizing hydrogels and cell encapsulation
2004 Standout
How were new medicines discovered?
2011 Standout
Regulation of antioxidant enzymes: a significant role for melatonin
2003 Standout
Melatonin Controls Seasonal Breeding by a Network of Hypothalamic Targets
2009
Influence of pineal indoleamines on the mitotic activity of gastric and colonic mucosa epithelial cells in the rat: Interaction with omeprazole
1991
Solubilization and Purification of Melatonin Receptors from Lizard Brain*
1990
Melatonin as a natural ally against oxidative stress: a physicochemical examination
2011 Standout
Major Depressive Disorder
2008 Standout
Characterization of a melatonin binding site in Siberian hamster brown adipose tissue
1997
2-[N-Acylamino(C1−C3)alkyl]indoles as MT1 Melatonin Receptor Partial Agonists, Antagonists, and Putative Inverse Agonists
1998
Pulse radiolysis studies of melatonin and chloromelatonin
1998
Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*
1991 Standout
Melatonin: A Multitasking Molecule
2010
Design, synthesis and pharmacological evaluation of new series of naphthalenic analogues as melatoninergic (MT1/MT2) and serotoninergic 5-HT2C dual ligands (I)
2012
Ramelteon (TAK-375) Accelerates Reentrainment of Circadian Rhythm after a Phase Advance of the Light-Dark Cycle in Rats
2005
Design, synthesis and melatoninergic activity of new unsubstituted and β,β′-difunctionalised 2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-6-alkanamides
2007
Structure Determination and Total Synthesis of (+)‐16‐Hydroxy‐16,22‐dihydroapparicine
2013 StandoutNobel
The Novel Melatonin Agonist Agomelatine (S20098) Is an Antagonist at 5-Hydroxytryptamine2C Receptors, Blockade of Which Enhances the Activity of Frontocortical Dopaminergic and Adrenergic Pathways
2003
TheCaenorhabditis elegansOrphan Nuclear Hormone Receptor Genenhr-2Functions in Early Embryonic Development
1997 StandoutNobel
Rotating Night Shifts and Risk of Breast Cancer in Women Participating in the Nurses' Health Study
2001
Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade
2004
Light Induction of a Vertebrate Clock Gene Involves Signaling through Blue-Light Receptors and MAP Kinases
2002 StandoutNobel
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
Melatonin binding sites in the central nervous system
1991
One molecule, many derivatives: A never‐ending interaction of melatonin with reactive oxygen and nitrogen species?
2006 Standout
Heterogeneity of the interflavanyl bond in proanthocyanidins from natural sources lacking C-4 (C-ring) deoxy flavonoid nucleophiles
2005
REVIEW: Gastrointestinal Melatonin: Localization, Function, and Clinical Relevance
2002 Standout
Molecular Neurogenetics of Biological Rhythms
1998 StandoutNobel
Arrestin and phosducin are expressed in a small number of brain cells
1997
The Nuclear Receptor for Melatonin Represses 5-Lipoxygenase Gene Expression in Human B Lymphocytes
1995
Solid-Phase Synthesis of Pyrroloisoquinolines via the Intramolecular N-Acyliminium Pictet−Spengler Reaction
2005 StandoutNobel
Signaling to the Mammalian Circadian Clocks: In Pursuit of the Primary Mammalian Circadian Photoreceptor
2001
Solid-Phase Intramolecular N-Acyliminium Pictet−Spengler Reactions as Crossroads to Scaffold Diversity
2004 StandoutNobel
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial
2016 Standout
Cryptochrome: The Second Photoactive Pigment in the Eye and Its Role in Circadian Photoreception
2000 StandoutNobel
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
CIRCADIAN RHYTHMS: Basic Neurobiology and Clinical Applications
1997
Pineal gland hormone melatonin binds and activates an orphan of the nuclear receptor superfamily.
1994
Novel difluoroacetamide analogues of agomelatine and melatonin: probing the melatonin receptors for MT1selectivity
2015
Cellular Mechanisms of Melatonin Action
1998
Practice parameter: Management of dementia (an evidence-based review) [RETIRED]
2001 Standout
Application and Analysis of the Folin Ciocalteu Method for the Determination of the Total Phenolic Content from Limonium Brasiliense L.
2013 Standout
Nature's knockout: the Mel1b receptor is not necessary for reproductive and circadian responses to melatonin in Siberian hamsters.
1996
Precise Modulation of CO2 Sorption in Ti8Ce2–Oxo Clusters: Elucidating Lewis Acidity of the Ce Metal Sites and Structural Flexibility
2024 StandoutNobel
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Dual Signaling of Human Mel1a Melatonin Receptors via Gi2, Gi3, and Gq/11 Proteins
1999
Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?
2015 Standout
Functional Expression of MT2 (Mel1b) Melatonin Receptors in Human PAZ6 Adipocytes
2001
Selective MT 2 melatonin receptor antagonists block melatonin‐mediated phase advances of circadian rhythms
1998
About Sleep's Role in Memory
2013 Standout
SYNTHESIS AND CHEMISTRY OF MELATONIN AND OF RELATED COMPOUNDS. A REVIEW
1995
Minireview: Cell protective role of melatonin in the brain
1995
Carcinogenicity of shift-work, painting, and fire-fighting
2007 Standout
Synthesis of a Novel Series of Tricyclic Indan Derivatives as Melatonin Receptor Agonists
2002
Synthesis of naphthopyrrolo[3,4-c]carbazoles
2001
Molecular Shape Diversity of Combinatorial Libraries: A Prerequisite for Broad Bioactivity
2003
PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues
2004 Standout
Electrogenerated Chemiluminescence and Its Biorelated Applications
2008 Standout
Extrapineal melatonin: sources, regulation, and potential functions
2014 Standout
The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks
2010 Standout
DESENSITIZATION OF G PROTEIN–COUPLED RECEPTORS AND NEURONAL FUNCTIONS
2004 StandoutNobel
Signaling to the Mammalian Circadian Clocks: In Pursuit of the Primary Mammalian Circadian Photoreceptor
2001
β-Turned Dipeptoids as Potent and Selective CCK1 Receptor Antagonists
2000
Role of Mouse Cryptochrome Blue-Light Photoreceptor in Circadian Photoresponses
1998 StandoutScienceNobel
Pertussis toxin-sensitive melatonin receptors negatively coupled to adenylate cyclase associated with cultured human and rat retinal pigment epithelial cells.
1995
Synthesis and biological activity of pyrrole, pyrroline and pyrrolidine derivatives with two aryl groups on adjacent positions
2006 Standout
Isolation and Synthesis of Biologically Active Carbazole Alkaloids
2002 Standout
Melatonin involvement in immunity and cancer
1998
Quantized Surface Complementarity Diversity (QSCD): A Model Based on Small Molecule−Target Complementarity
2000
Partially Modified Retro-Inverso Peptides: Development, Synthesis, and Conformational Behavior
1998
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
2011 StandoutNobel
Works of H.E. Howell being referenced
Synthesis and Structure-Activity Relationships of Novel Naphthalenic and Bioisosteric Related Amidic Derivatives as Melatonin Receptor Ligands
1994
Characterisation of human melatonin mt1 and MT2 receptors by CRE-luciferase reporter assay
2000
Synthesis and structure–activity relationships of novel naphthalenic and bioisosteric related amidic derivatives as melatonin receptor ligands
1998
Melatonin receptors: Localization, molecular pharmacology and physiological significance
1994
Novel naphthalenic ligands with high affinity for the melatonin receptor
1992
Tetrahydronaphthalenic derivatives as new agonist and antagonist ligands for melatonin receptors
1998
Identification of Two Novel Promelacacinidin Dimers from Acacia nigrescens
2002
MELATONIN INHIBITS CYCLIC AMP PRODUCTION IN CULTURED OVINE PARS TUBERALIS CELLS
1989
Melatonin Receptor Sites in the Syrian Hamster Brain and Pituitary. Localization and Characterization Using [125|]lodomelatonin*
1989