Citation Impact
Citing Papers
Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
2010 StandoutNobel
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
Tissue expression of PD-L1 mediates peripheral T cell tolerance
2006
Dendritic cell–expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
2007 StandoutNobel
Identification of a Primary Target of Thalidomide Teratogenicity
2010 StandoutScience
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
2013 StandoutScience
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Protein O -fucosyltransferase 1 is an essential component of Notch signaling pathways
2003
Th17 Polarized Cells from Nonobese Diabetic Mice Following Mycobacterial Adjuvant Immunotherapy Delay Type 1 Diabetes
2010
Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice
2009
Functional Interaction between SEL-10, an F-box Protein, and the Nuclear Form of Activated Notch1 Receptor
2001 StandoutNobel
T‐cell fate
1998
A Mutant Stat5b with Weaker DNA Binding Affinity Defines a Key Defective Pathway in Nonobese Diabetic Mice
2004
Dissecting autoimmune diabetes through genetic manipulation of non-obese diabetic mice
2003
Notch function in the vasculature: insights from zebrafish, mouse and man
2004
Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library
1999
Perforin-independent β-cell destruction by diabetogenic CD8+ T lymphocytes in transgenic nonobese diabetic mice
1999
The Nonobese Diabetic Mouse as a Model of Autoimmune Diabetes: Immune Dysregulation Gets the NOD
1997
Gender Bias in Autoimmunity Is Influenced by Microbiota
2013
Nas transgenic mouse line allows visualization of Notch pathway activity in vivo
2006
The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice
2005
Genes and Cellular Requirements for Autoimmune Diabetes Susceptibility in Nonobese Diabetic Mice
2001
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
1999 StandoutNature
The Effect of Infections on Susceptibility to Autoimmune and Allergic Diseases
2002 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity
1995
Regulation of αβ/γδ T Cell Lineage Commitment and Peripheral T Cell Responses by Notch/RBP-J Signaling
2004 StandoutNobel
The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it
2005
Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand–receptor interactions in intrathymic T cell development
1999
Interpreting Neonatal Lethal Phenotypes in Mouse Mutants: Insights Into Gene Function and Human Diseases
2009
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
Local Expression of TNFα in Neonatal NOD Mice Promotes Diabetes by Enhancing Presentation of Islet Antigens
1998
Efficacy of B-Cell–Targeted Therapy with Rituximab in Patients with Rheumatoid Arthritis
2004 Standout
Notch signaling in T cell development
2000
Palatal fusion – Where do the midline cells go?
2006
Regulation of lymphocyte development by Notch signaling
2007 StandoutNobel
Notch regulation of lymphocyte development and function
2004
Notch and the Immune System
2003
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells
2009
Long‐term comparison of rituximab treatment for refractory systemic lupus erythematosus and vasculitis: Remission, relapse, and re‐treatment
2006
During the Early Prediabetic Period in NOD Mice, the Pathogenic CD8+ T-Cell Population Comprises Multiple Antigenic Specificities
2002
Neurons derived from radial glial cells establish radial units in neocortex
2001 StandoutNature
Increased islet antigen presentation leads to type‐1 diabetes in mice with autoimmune susceptibility
2004
Systemic Lupus Erythematosus
2011 Standout
Notch and the Immune System
1999
The Stages of Type 1A Diabetes
2005
Cancer immunotherapy comes of age
2011 StandoutNature
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Speed congenics: a classic technique in the fast lane (relatively speaking)
1997
FOXP3+ regulatory T cells in the human immune system
2010 StandoutNobel
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
1999 StandoutNature
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
The basics of epithelial-mesenchymal transition
2009 Standout
Rituximab versus Cyclophosphamide in ANCA-Associated Renal Vasculitis
2010 Standout
Long-Term Potentiation Is Reduced in Mice That Are Doubly Mutant in Endothelial and Neuronal Nitric Oxide Synthase
1996 StandoutNobel
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Leptin and the regulation of body weight in mammals
1998 StandoutNature
Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice
1997
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Embryonic Lethality and Vascular Defects in Mice Lacking the Notch Ligand Jagged1
1999
Development of Insulitis and Diabetes in B Cell-Deficient NOD Mice
1997
Radial Glial Identity Is Promoted by Notch1 Signaling in the Murine Forebrain
2000
Notch1 and Notch3 Instructively Restrict bFGF-Responsive Multipotent Neural Progenitor Cells to an Astroglial Fate
2001 StandoutNobel
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
2008 StandoutNature
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants
2004 StandoutNobel
A Case for Regulatory B Cells
2006
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
Investigation of the Role of B-Cells in Type 1 Diabetes in the NOD Mouse
2004
Notch-dependent control of myelopoiesis is regulated by fucosylation
2008
Interferon-γ impacts at multiple points during the progression of autoimmune diabetes
1997
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25−T cells into islet-protective Foxp3+regulatory T cells
2007 StandoutNobel
Use of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance gene.
1994
Dll4, a novel Notch ligand expressed in arterial endothelium
2000
Stage-Specific and Differential Notch Dependency at the αβ and γδ T Lineage Bifurcation
2006
Notch signaling is essential for vascular morphogenesis in mice
2000 Standout
REGULATION OF LYMPHOID DEVELOPMENT, DIFFERENTIATION, AND FUNCTION BY THE NOTCH PATHWAY
2005
T-Cell Compartments of Prediabetic NOD Mice
2003
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
2011 StandoutNobel
Expansion of Human Regulatory T-Cells From Patients With Type 1 Diabetes
2008
Ligand endocytosis drives receptor dissociation and activation in the Notch pathway
2000
Identification of a CD8 T Cell That Can Independently Mediate Autoimmune Diabetes Development in the Complete Absence of CD4 T Cell Helper Functions
2000
Signalling interactions during facial development
1998
Initiation of Autoimmune Diabetes by Developmentally Regulated Presentation of Islet Cell Antigens in the Pancreatic Lymph Nodes
1999
Regulation of intrathymic T‐cell development by Lunatic Fringe– Notch1 interactions
2006
BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling
2007
Isoforms of nitric oxide synthase
1995
Identification of MHC Class II-Restricted Peptide Ligands, Including a Glutamic Acid Decarboxylase 65 Sequence, that Stimulate Diabetogenic T Cells from Transgenic BDC2.5 Nonobese Diabetic Mice
2001
Progression to Islet Destruction in a Cyclophosphamide-Induced Transgenic Model
2004
IL-12 Administration Accelerates Autoimmune Diabetes in Both Wild-Type and IFN-γ-Deficient Nonobese Diabetic Mice, Revealing Pathogenic and Protective Effects of IL-12-Induced IFN-γ
2003
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
PD-1 deficiency reveals various tissue-specific autoimmunity by H-2band dose-dependent requirement of H-2g7for diabetes in NOD mice
2008 StandoutNobel
A Chemical Reporter Strategy to Probe Glycoprotein Fucosylation
2006 StandoutNobel
A Novel Mouse with B Cells but Lacking Serum Antibody Reveals an Antibody-independent Role for B Cells in Murine Lupus
1999
Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells
2000 StandoutNobel
Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein
1997 StandoutScience
Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of β cells
2007 StandoutNobel
CD25+ CD4+ T Cells, Expanded with Dendritic Cells Presenting a Single Autoantigenic Peptide, Suppress Autoimmune Diabetes
2004 StandoutNobel
Pancreas-Infiltrating Th1 Cells and Diabetes Develop in IL-12-Deficient Nonobese Diabetic Mice
1999
Programmed death-1 concentration at the immunological synapse is determined by ligand affinity and availability
2007 StandoutNobel
T Cell Activation in Rheumatoid Synovium Is B Cell Dependent
2001
Tissue-specific expression of B7x protects from CD4 T cell–mediated autoimmunity
2011 StandoutNobel
Differential Effects of Notch Ligands Delta-1 and Jagged-1 in Human Lymphoid Differentiation
2001
Th1 to Th2 Cytokine Shifts in Nonobese Diabetic Mice: Sometimes an Outcome, Rather Than the Cause, of Diabetes Resistance Elicited by Immunostimulation
2001
Enhanced Pathogenicity of Diabetogenic T Cells Escaping a Non-MHC Gene-Controlled Near Death Experience
2004
Spontaneous Autoimmune Diabetes in Monoclonal T Cell Nonobese Diabetic Mice
1997
Autoreactive Diabetogenic T-Cells in NOD Mice Can Efficiently Expand From a Greatly Reduced Precursor Pool
2001
Recombination signal sequence-binding protein Jκ alters mesodermal cell fate decisions by suppressing cardiomyogenesis
2003 StandoutNobel
Binding of Delta1, Jagged1, and Jagged2 to Notch2 Rapidly Induces Cleavage, Nuclear Translocation, and Hyperphosphorylation of Notch2
2000
Works of H.D. Chapman being referenced
The inducible nitric oxide synthase gene, Nos2, maps to mouse Chromosome 11
1994
Obesity-induced diabetes (diabesity) in C57BL/KsJ mice produces aberrant trans-regulation of sex steroid sulfotransferase genes.
1994
Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice
1998
Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent.
1997
Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice.
2000
B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.
1996