Citation Impact
Citing Papers
MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18
2010
Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model
2013
TLR9 Is Critical for Glioma Stem Cell Maintenance and Targeting
2014
Effective treatment of severe COVID-19 patients with tocilizumab
2020 Standout
MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice
2018
Hallmarks of Cancer: The Next Generation
2011 Standout
Inactivation of IL11 Signaling Causes Craniosynostosis, Delayed Tooth Eruption, and Supernumerary Teeth
2011
Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells
2017
Cytokines in inflammatory bowel disease
2014 Standout
Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity
2014 Nature
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
2012 Standout
Inflammation and Cancer: Triggers, Mechanisms, and Consequences
2019 Standout
Oxidative stress, inflammation, and cancer: How are they linked?
2010 Standout
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
The Interleukin-6 Family Cytokine Interleukin-11 Regulates Homeostatic Epithelial Cell Turnover and Promotes Gastric Tumor Development
2008
EMT and Dissemination Precede Pancreatic Tumor Formation
2012 Standout
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
2014 Standout
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
The mini-driver model of polygenic cancer evolution
2015 StandoutNobel
Coordinated regulation of myeloid cells by tumours
2012 Standout
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences
2022 StandoutNobel
Tumor-Associated Macrophages: From Mechanisms to Therapy
2014 Standout
gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis
2009
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Application potential of toll-like receptors in cancer immunotherapy
2016
Targeting the NLRP3 inflammasome in inflammatory diseases
2018
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
Inflammation and Colon Cancer
2010 Standout
Identification of Putative Target Genes of the Transcription Factor RUNX2
2013 StandoutNobel
Immunity, Inflammation, and Cancer
2010 Standout
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
2011
STATs in cancer inflammation and immunity: a leading role for STAT3
2009 Standout
Stat3 and MMP7 Contribute to Pancreatic Ductal Adenocarcinoma Initiation and Progression
2011
Alternative Activation of Macrophages: Mechanism and Functions
2010 Standout
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
2014 Standout
IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
2009 Standout
The microbiome and cancer
2013
Inflammation and oncogenesis: a vicious connection
2009
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours
2008 Nature
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms
2013 Standout
Mitochondria as multifaceted regulators of cell death
2019 Standout
Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy
2017 Standout
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Diverse mechanisms for inflammasome sensing of cytosolic bacteria and bacterial virulence
2015
Cancer-related inflammation
2008 StandoutNature
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Signal Transducer and Activator of Transcription‐3, Inflammation, and Cancer
2009 Standout
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Bile Acid and Inflammation Activate Gastric Cardia Stem Cells in a Mouse Model of Barrett-Like Metaplasia
2012
Berberine may rescue Fusobacterium nucleatum-induced colorectal tumorigenesis by modulating the tumor microenvironment
2015
Inferring tumour purity and stromal and immune cell admixture from expression data
2013 Standout
More than a sidekick: the IL-6 family cytokine IL-11 links inflammation to cancer
2010
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Bidirectional regulation between TMEFF2 and STAT3 may contribute to H elicobacter pylori‐associated gastric carcinogenesis
2014
Four faces of cellular senescence
2011 Standout
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
IKK/NF‐κB and STAT3 pathways: central signalling hubs in inflammation‐mediated tumour promotion and metastasis
2009
Irradiation and anti–PD-L1 treatment synergistically promote antitumor immunity in mice
2014 Standout
gp130 at the nexus of inflammation, autoimmunity, and cancer
2010
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
N‐Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen‐Presenting Cells through Dectin‐1 and Dectin‐2
2018 StandoutNobel
Promising Targets for Cancer Immunotherapy: TLRs, RLRs, and STING-Mediated Innate Immune Pathways
2017
Works of Hazel Tye being referenced
Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β
2015
Inflammation modulates the expression of the intestinal mucins MUC2 and MUC4 in gastric tumors
2010
STAT3 and STAT1 mediate IL-11–dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice
2008
Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis
2013
STAT3-Driven Upregulation of TLR2 Promotes Gastric Tumorigenesis Independent of Tumor Inflammation
2012
Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome
2017