Citation Impact
Citing Papers
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation
2019 StandoutNobel
Shewanella secretes flavins that mediate extracellular electron transfer
2008 Standout
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
Cloning, Expression, and Functional Characterization of the Substrate Binding Subunit of Rat Type II Iodothyronine 5′-Deiodinase
2000
Characterization of the Subunit Structure of the Catalytically Active Type I Iodothyronine Deiodinase
2001
Cryptochrome, Circadian Cycle, Cell Cycle Checkpoints, and Cancer
2005 StandoutNobel
Reactive oxygen species, mitochondria, apoptosis and aging
1997
Degradation and Recycling of the Substrate-binding Subunit of Type II Iodothyronine 5′-Deiodinase in Astrocytes
1996
The Spike of S Phase Cyclin Cig2 Expression at the G1–S Border in Fission Yeast Requires Both APC and SCF Ubiquitin Ligases
2000 StandoutNobel
Cardiolipins and biomembrane function
1992
Sepsis biomarkers: a review
2010 Standout
Topology of Superoxide Production from Different Sites in the Mitochondrial Electron Transport Chain
2002 Standout
Generation of Human Melanocytes from Induced Pluripotent Stem Cells
2011 StandoutNobel
A review of genetic disorders of hypopigmentation: lessons learned from the biology of melanocytes
2009
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
2006 StandoutNature
Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants
1996
Potential health impacts of excessive flavonoid intake
2000
Type I iodothyronine deiodinase is a selenocysteine-containing enzyme
1991 StandoutNature
Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1
1999 Standout
Balancing Acts
2004 Standout
Central sensitization: Implications for the diagnosis and treatment of pain
2010 Standout
Selenium and human health
2012 Standout
Dietary Flavonoids as Potential Neuroprotectants
2002
Catalase function in plants: a focus on Arabidopsis mutants as stress-mimic models
2010
The Role of Selenium in Thyroid Hormone Action*
1992
Anticarcinogenic actions of melatonin which involve antioxidative processes: comparison with other antioxidants
2001
A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis
1998 Standout
Transition-state analogue inhibitors of γ-secretase bind directly to presenilin-1
2000
Copper–O2 reactivity of tyrosinase models towards external monophenolic substrates: molecular mechanism and comparison with the enzyme
2011
Thyroid disrupting chemicals: mechanisms and mixtures
2008
The biochemistry and medical significance of the flavonoids
2002 Standout
Investigation of type I and type III iodothyronine deiodinases in rat tissues using N-bromoacetyl-iodothyronine affinity labels
1995
Topological Analysis of the Integral Membrane Protein, Type 1 Iodothyronine Deiodinase (D1)
1995
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
2000 Standout
Flavonoids: a review of probable mechanisms of action and potential applications
2001 Standout
Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3,5-diiodo-l-thyronine and by 3,3′-diiodo-l-thyronine
1994
A 43-kDa Protein Related to c-Erb A α1 Is Located in the Mitochondrial Matrix of Rat Liver
1995
Thyroid hormone action: Effect of triiodothyronine on mitochondrial adenine nucleotide translocase in vivo and in vitro
1995
Male breast cancer
2006 Standout
Polyphenols: food sources and bioavailability
2004 Standout
Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis
2015
Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
2011 Standout
Uncoupling: new approaches to an old problem of bioenergetics
1998
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
“Transcription physiology” of pigment formation in melanocytes: central role of MITF
2010
The trace element selenium and the thyroid gland
1999
The Human Type 2 Iodothyronine Deiodinase Is a Selenoprotein Highly Expressed in a Mesothelioma Cell Line
2001
Sarcoidosis
1997 Standout
Pathobiology of chemotherapy-induced hair loss
2013
Structure-effect relationships of amiodarone analogues on the inhibition of thyroxine deiodination
2000
Role of Free Radicals in the Neurodegenerative Diseases
2001 Standout
The immunopathology of sepsis and potential therapeutic targets
2017 Standout
Astrocyte–endothelial interactions at the blood–brain barrier
2005 Standout
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Thyroid hormone regulation of mitochondrial function
1990
The relationship between electromagnetic field and light exposures to melatonin and breast cancer risk: A review of the relevant literature
1999
Expression of Chicken Hepatic Type I and Type III Iodothyronine Deiodinases during Embryonic Development1
1997
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Rotating Night Shifts and Risk of Breast Cancer in Women Participating in the Nurses' Health Study
2001
Identification of type I iodothyronine 5′-deiodinase as a selenoenzyme
1990
The influence of the cytokines Il‐1β and INFγ on the expression of selenoproteins in the human hepatocarcinoma cell line HepG2
2000
Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype
2008
Concomitant Raman spectroscopy and dynamic light scattering for characterization of therapeutic proteins at high concentrations
2014
DLS and zeta potential – What they are and what they are not?
2016 Standout
Myosin V Plays an Essential Role in the Thyroid Hormone-dependent Endocytosis of Type II Iodothyronine 5′-Deiodinase
2000
Metabolic Effects of Thyroid Hormone Derivatives
2008
Biosynthesis of Vitamin B2 (Riboflavin)
2000
Thyroid-Disrupting Chemicals: Interpreting Upstream Biomarkers of Adverse Outcomes
2009
Oxidative damage and mitochondrial decay in aging.
1994 Standout
Notch receptor cleavage depends on but is not directly executed by presenilins
2002 StandoutNobel
Cutting Edge: Antisense Knockdown of Inducible Nitric Oxide Synthase Inhibits Induction of Experimental Autoimmune Encephalomyelitis in SJL/J Mice
1998 StandoutNobel
Identification of critical amino acids for 3,5,3'-triiodothyronine deiodination by human type 1 deiodinase based on comparative functional-structural analyses of the human, dog, and rat enzymes.
1994
Local activation and inactivation of thyroid hormones: the deiodinase family
1999
Catalytic Activity of Type II Iodothyronine 5′-Deiodinase Polypeptide Is Dependent upon a Cyclic AMP Activation Factor
1996
Retinoids stimulate type I iodothyronine 5'-deiodinase activity in human follicular thyroid carcinoma cell lines.
1994
Copper Active Sites in Biology
2014 Standout
Biochemistry, Cellular and Molecular Biology, and Physiological Roles of the Iodothyronine Selenodeiodinases
2002 Standout
Identification of essential histidine residues in rat type I iodothyronine deiodinase.
1992
The Mammalian Homolog of the Frog Type II Selenodeiodinase Does Not Encode a Functional Enzyme in the Rat*
1999
How mitochondria produce reactive oxygen species
2008 Standout
Thyronamines—Past, Present, and Future
2011
Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator
2003 Standout
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Biosynthesis of riboflavin: characterization of the bifunctional deaminase-reductase of Escherichia coli and Bacillus subtilis
1997
Highly Oxidized Peroxisomes Are Selectively Degraded via Autophagy in Arabidopsis
2013 StandoutNobel
Physiological and Molecular Basis of Thyroid Hormone Action
2001 Standout
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
Thyroid Hormone Regulation of Metabolism
2014 Standout
Elevated serum neopterin levels in sarcoidosis
1986
Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
2012 Standout
Localization of type I iodothyronine 5'-deiodinase to the basolateral plasma membrane in renal cortical epithelial cells
1991
The Role of the Active Site Cysteine in Catalysis by Type 1 Iodothyronine Deiodinase*
1997
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
2000 Standout
Chemistry of Biologically Important Synthetic Organoselenium Compounds
2001 Standout
“Mild” Uncoupling of Mitochondria
1997
Identification by photoaffinity labeling of a membrane thyroid hormone-binding protein associated with the triiodothyronine transport system in rat erythrocytes.
1993
Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase.
1992
Biogenesis of γ-secretase early in the secretory pathway
2007 StandoutNobel
Molecular Aspects of Thyroid Hormone Actions
2010
EPR, ENDOR, and TRIPLE Resonance Spectroscopy on the Neutral Flavin Radical in Escherichia coli DNA Photolyase
1999 StandoutNobel
Characterization of a Propylthiouracil-Insensitive Type I Iodothyronine Deiodinase*
1997
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Comparison of the physicochemical properties of type I and type II iodothyronine 5'-deiodinase.
1991
CSF neopterin as marker of disease activity in multiple sclerosis
1987
Carbon Dioxide Capture in Metal–Organic Frameworks
2011 Standout
Reactive oxygen species, mitochondria, apoptosis and aging
1997
Works of Hartmut Rokos being referenced
Serial Transplants of DMBA-Induced Mammary Tumors in Fischer Rats as a Model System for Human Breast Cancer
1999
3,5-Di-iodo-l-thyronine suppresses TSH in rats in vivo and in rat pituitary fragments in vitro
1995
Butyrylcholinesterase is present in the human epidermis and is regulated by H2O2: More evidence for oxidative stress in vitiligo
2006
Computer Simulation of Native Epidermal Enzyme Structures in the Presence and Absence of Hydrogen Peroxide (H2O2): Potential and Pitfalls
2006
A novel mechanism in control of human pigmentation by β-melanocyte-stimulating hormone and 7-tetrahydrobiopterin
2005
GTP Cyclohydrolase Feedback Regulatory Protein Controls Cofactor 6-Tetrahydrobiopterin Synthesis in the Cytosol and in the Nucleus of Epidermal Keratinocytes and Melanocytes
2006
The redox – biochemistry of human hair pigmentation
2010
Cholesterol regulates melanogenesis in human epidermal melanocytes and melanoma cells
2009
Thyroid hormone effect on rat heart mitochondrial proteins and affinity labeling with N‐bromoacetyl‐3,3′,5‐triiodo‐L‐thyronine Lack of direct effect on the adenine nucleotide translocase
1989
Effect of septicaemia on the plasma levels of biopterin and nitric oxide metabolites in rats and rabbits
1996
Different Tissue Distribution, Elimination, and Kinetics of Thyroxine and Its Conformational Analog, the Synthetic Flavonoid EMD 49209 in the Rat1
1997
Serial Transplants of DMBA-Induced Mammary Tumors in Fischer Rats as Model System for Human Breast Cancer
1995
Selenium-dependent regulation of type I 5′-deiodinase expression
1993
Structural requirements of iodothyronines for the rapid inactivation and internalization of type II iodothyronine 5'-deiodinase in glial cells
1993
Rapid stimulation of hepatic oxygen consumption by 3,5-di-iodo-l -thyronine
1989
In vivo fluorescence excitation spectroscopy and in vivo Fourier‐transform Raman spectroscopy in human skin: evidence of H2O2 oxidation of epidermal albumin in patients with vitiligo
2004
Synthetic flavonoids cross the placenta in the rat and are found in fetal brain
1998
Biosynthesis of riboflavin 6,7-dimethyl-8-ribityllumazine 5′-phosphate is not a substrate for riboflavin synthase
1978
Senile hair graying: H 2 O 2 ‐mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair
2009
Rat liver iodothyronine monodeiodinase. Evaluation of the iodothyronine ligand-binding site.
1986
Selective affinity labeling of a 27-kDa integral membrane protein in rat liver and kidney with N-bromoacetyl derivatives of L-thyroxine and 3,5,3'-triiodo-L-thyronine.
1990
Raised serum neopterin levels and imbalances of T-lymphocyte subsets in viral diseases, acquired immune deficiency and related lymphadenopathy syndromes.
1984
Affinity labeling of rat liver and kidney type I 5'-deiodinase. Identification of the 27-kDa substrate binding subunit.
1990
Molecular Structure And Biochemical Activity Of 3,5,3′-Triiodothyronamine
1984