Standout Papers
- Femtomole sensitive radioimmunoassay for cyclic AMP and cyclic GMP after 2'0 acetylation by acetic anhydride in aqueous solution. (1975)
Citation Impact
Citing Papers
Immunocytology on microwave-fixed cells reveals rapid and agonist-specific changes in subcellular accumulation patterns for cAMP or cGMP.
1990
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
S. cerevisiae α pheromone receptors activate a novel signal transduction pathway for mating partner discrimination
1991 StandoutNobel
Germline mutations in the thyrotropin receptor gene cause non–autoimmune autosomal dominant hyperthyroidism
1994
The GTPase superfamily: conserved structure and molecular mechanism
1991 StandoutNature
Persistent and transcriptionally-dependent increase in protein phosphorylation in long-term facilitation ofAplysia sensory neurons
1989 StandoutNatureNobel
Cyclic nucleotide research — still expanding after half a century
2002 Standout
Localization of nitric oxide synthase indicating a neural role for nitric oxide
1990 StandoutNature
FMRFamide reverses protein phosphorylation produced by 5-HT and cAMP in Aplysia sensory neurons
1989 StandoutNatureNobel
Nitric Oxide as a Mediator of Relaxation of the Corpus Cavernosum in Response to Nonadrenergic, Noncholinergic Neurotransmission
1992 StandoutNobel
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
Mechanisms of action of a second generation growth hormone-releasing peptide (Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2) in rat anterior pituitary cells.
1993
Atrial Natriuretic Peptide, Oxytocin, and Vasopressin Increase Guanosine 3′,5′-Monophosphate in LLC-PK1Kidney Epithelial Cells*
1988 StandoutNobel
On the stimulation of soluble and particulate guanylate cyclase in the rat brain and the involvement of nitric oxide as studied by cGMP immunocytochemistry
1992
Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation
1994 StandoutNatureNobel
Cyclic adenosine 5'-monophosphate in Escherichia coli
1976
Cigarette Smoke Activates Guanylate Cyclase and Increases Guanosine 3′,5′-Monophosphate in Tissues
1977 StandoutScienceNobel
Relationships between seizure activity and cyclic nucleotide levels in brain
1980
Production and characterization of monoclonal antibodies to soluble rat lung guanylate cyclase.
1981 StandoutNobel
Atrial natriuretic factor elicits an endothelium-independent relaxation and activates particulate guanylate cyclase in vascular smooth muscle.
1984 StandoutNobel
Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons
1993 StandoutScienceNobel
Ontogeny of adenosine 3?,5?-monophosphate metabolism in guinea pig cerebral cortex
1987
cAMP induces a rapid and reversible modification of the chemotactic receptor in Dictyostelium discoideum.
1985
Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation
1983 StandoutNatureNobel
An activity in rat tissues that modifies nitrotyrosine-containing proteins
1998 StandoutNobel
Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations
1977 StandoutNobel
Membrane responses and changes in cAMP levels in Aplysia sensory neurons produced by serotonin, tryptamine, FMRFamide and small cardioactive peptideB (SCPB)
1985
Associative conditioning analog selectively increases cAMP levels of tail sensory neurons in Aplysia.
1985
Evidence for the inhibitory role of guanosine 3', 5'-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators
1981
An M2 Muscarinic Receptor Subtype Coupled to Both Adenylyl Cyclase and Phosphoinositide Turnover
1987 Science
Beta adrenergic receptors in lymphocyte subpopulations
1980 StandoutNobel
Ontogeny of adenosine 3?,5?-monophosphate metabolism in rabbit cerebral cortex
1987
Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells.
1982
Protein synthesis during acquisition of long-term facilitation is needed for the persistent loss of regulatory subunits of the Aplysia cAMP-dependent protein kinase.
1990 StandoutNobel
β-Adrenergic Receptor Kinase: Primary Structure Delineates a Multigene Family
1989 StandoutScienceNobel
Cachectin alters anterior pituitary hormone release by a direct action in vitro.
1989 StandoutNobel
Dopaminergic stimulation of cyclic AMP accumulation and parathyroid hormone release from dispersed bovine parathyroid cells
1977
Mechanisms of adenosine triphosphate-, thrombin-, and trypsin-induced relaxation of rat thoracic aorta.
1984 StandoutNobel
Molecular Biology of Learning: Modulation of Transmitter Release
1982 StandoutScienceNobel
A model of anthrax toxin lethal factor bound to protective antigen
2005 StandoutNobel
Activation of purified soluble guanylate cyclase by protoporphyrin IX.
1982 StandoutNobel
Purification of soluble guanylate cyclase from rat liver
1979 StandoutNobel
Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice
2000 StandoutNobel
Chloride secretory mechanism induced by prostaglandin E1 in a colonic epithelial cell line.
1985
Inhibition of Escherichia coli heat-stable enterotoxin by indomethacin and chlorpromazine
1980 StandoutNobel
Phosphodiesterase 4D is required for β 2 adrenoceptor subtype-specific signaling in cardiac myocytes
2005 StandoutNobel
Epidermal growth factor mimics insulin effects in rat hepatocytes
1986
Multiple receptors for dopamine
1979 StandoutNature
1997 StandoutNobel
Tail shock produces inhibition as well as sensitization of the siphon-withdrawal reflex of Aplysia: possible behavioral role for presynaptic inhibition mediated by the peptide Phe-Met-Arg-Phe-NH2.
1987 StandoutNobel
Spatiotemporal dynamics of guanosine 3′,5′-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator
2001 StandoutNobel
Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels
1987 StandoutNatureNobel
Deduced primary structure of the alpha subunit of the GTP-binding stimulatory protein of adenylate cyclase.
1986 StandoutNobel
Activation of Intestinal Guanylate Cyclase by Heat-Stable Enterotoxin of Escherichia coli: Studies of Tissue Specificity, Potential Receptors, and Intermediates
1980 StandoutNobel
Impaired growth and fertility of cAMP-specific phosphodiesterase PDE4D-deficient mice
1999
Activation of guanylate cyclase by superoxide dismutase and hydroxyl radical: a physiological regulator of guanosine 3',5'-monophosphate formation.
1977 StandoutNobel
The structure of a CAP–DNA complex having two cAMP molecules bound to each monomer
1997 StandoutNobel
Ligand-induced overexpression of a constitutively active β 2 -adrenergic receptor: Pharmacological creation of a phenotype in transgenic mice
1997 StandoutNobel
The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families.
1996
Evidence for cyclic GMP-mediated relaxant effects of nitro-compounds in coronary smooth muscle
1979
Effect of sodium-potassium pump inhibitors and membrane-depolarizing agents on sodium nitroprusside-induced relaxation and cyclic guanosine monophosphate accumulation in rat aorta.
1985 StandoutNobel
Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells
1987
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1999 StandoutNature
Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin
1984 StandoutNobel
Enzymatic regulation of the concentration of cyclic GMP in mouse brain
1978
Characterization, cloning and sequence analysis of the CDC25 gene which controls the cyclic AMP level of Saccharomyces cerevisiae.
1986
Immunohistochemical localization of guanylate cyclase within neurons of rat brain.
1982 StandoutNobel
Lanthanum chloride inhibition of the secretory response to Escherichia coli heat-stable enterotoxin
1982 StandoutNobel
Cyclic GMP Accumulation Causes Degeneration of Photoreceptor Cells: Simulation of an Inherited Disease
1977 Science
Ontogeny of adenosine 3?,5?-monophosphate metabolism in guinea pig cerebral cortex
1987
Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase.
1991 StandoutNobel
Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits
1991 StandoutScienceNobel
Stimulation of protein phosphatase activity by insulin and growth factors in 3T3 cells.
1988 StandoutNobel
Effect of in vitro organic nitrate tolerance on relaxation, cyclic GMP accumulation, and guanylate cyclase activation by glyceryl trinitrate and the enantiomers of isoidide dinitrate.
1988 StandoutNobel
NG-methyl-L-arginine causes endothelium-dependent contraction and inhibition of cyclic GMP formation in artery and vein.
1990 StandoutNobel
Works of Harper Jf being referenced
Femtomole sensitive radioimmunoassay for cyclic AMP and cyclic GMP after 2'0 acetylation by acetic anhydride in aqueous solution.
1975 Standout
Radioimmunoassay of cyclic AMP and cyclic GMP.
1979