Citation Impact
Citing Papers
Direct observation of thymine dimer repair in DNA by photolyase
2005 StandoutNobel
Accelerated telomere shortening in response to life stress
2004 StandoutNobel
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
Human Ageing and Telomeres
2007
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Analysis of photoernzymatic repair of UV lesions in DNA by single light flashes. XI. Light-induced activation of the yeast photoreactivating enzyme
1976
Light-flash analysis of the photoenzymic repair process in yeast cells
1978
Molecular characterization of a gene encoding a photolyase fromStreptomycesgriseus
1989
DNA photolyases: Physical properties, action mechanism, and roles in dark repair
1990
Cellular senescence: when bad things happen to good cells
2007 Standout
The energetics of genome complexity
2010 Nature
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
Telomerase activity in bladder carcinoma and its implication for noninvasive diagnosis by detection of exfoliated cancer cells in urine
1997
DNA PHOTOLYASE FROM THE FUNGUS NEUROSPORA CRASSA. PURIFICATION, CHARACTERIZATION AND COMPARISON WITH OTHER PHOTOLYASES
1994
Telomere states and cell fates
2000 StandoutNatureNobel
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
1997 StandoutNobel
The Hallmarks of Cancer
2000 Standout
TIN2, a new regulator of telomere length in human cells
1999
The roles of telomeres and telomerase in cell life span
1996
Correlating telomerase activity levels with human neuroblastoma outcomes
1995
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
Secondary Structure of Vertebrate Telomerase RNA
2000 StandoutNobel
Telomerase in human development and cancer
1997
DNA repair catalyzed by Escherichia coli DNA photolyase containing only reduced flavin: elimination of the enzyme's second chromophore by reduction with sodium borohydride
1987
High-level expression of the photorepair gene in Drosophila ovary and its evolutionary implications
1994
The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2
1998
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
Comparative biology of mouse versus human cells: modelling human cancer in mice
2003
The biology of replicative senescence
1997
The two-stage mechanism controlling cellular senescence and immortalization
1992
Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals
1998
Neandertal DNA Sequences and the Origin of Modern Humans
1997 StandoutNobel
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Switching and Signaling at the Telomere
2001 StandoutNobel
Insertions and duplications of mtDNA in the nuclear genomes of Old World monkeys and hominoids
1995 Nature
Characterization of a Medium Wavelength Type DNA Photolyase: Purification and Properties of Photolyase from Bacillus firmus
1994 StandoutNobel
Telomerase activity in human germline and embryonic tissues and cells
1996
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
Enzymatic photoreactivation: 50 years and counting
2000
Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
2001 Nature
Telomerase Activity in Human Breast Tumors
1996
Inhibition of telomerase limits the growth of human cancer cells
1999
Telomerase activation in normal B lymphocytes and non-Hodgkin's lymphomas
1996
Cloning of the phr gene and amplification of photolyase in Escherichia coli
1978 StandoutNobel
DNA photoreactivating enzyme from the cyanobacterium Anacystis nidulans.
1990
A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
1995 Standout
Epidermal Growth Factor: High and Low Molecular Weight Forms
1970 StandoutNobel
PHOTOSENSITIZATION OF PYRIMIDINE DIMER SPLITTING BY A COVALENTLY BOUND INDOLE
1987
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
1999 StandoutNobel
Action mechanism of ABC excision nuclease on a DNA substrate containing a psoralen crosslink at a defined position.
1986 StandoutNobel
Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation.
1993
Naturally occurring 5-deazaflavin coenzymes: biological redox roles
1986
PHOTOREACTIVATING ENZYME FROM STREPTOMYCES GRISEUS—IV. ON THE NATURE OF THE CHROMOPHORIC COFACTOR IN STREPTOMYCES GRISEUS PHOTOREACTIVATING ENZYME
1981
Homology between the photoreactivation genes of Saccharomyces cerevisiae and Escherichia coli
1985
Amino Acid Racemization and the Preservation of Ancient DNA
1996 StandoutScienceNobel
Telomerase activity, cell proliferation, and cancer
1998 StandoutNobel
Escherichia coli DNA photolyase is a flavoprotein
1984 StandoutNobel
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Mechanisms of Bile Acid Biosynthesis Studied with 3α-3H- and 4β-3H-Cholesterol
1964 StandoutNobel
Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes
1994
Ku is associated with the telomere in mammals
1999 StandoutNobel
Photoreactivation in Methanobacterium thermoautotrophicum
1985
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Sequence of theSaccharomyces cerevisiae PHRIgene and homology of thePHRIphotolyase toE. coliphotolyase
1985
Photoreactivating enzyme from the green alga Scenedesmus acutus. Evidence for the presence of two different flavin chromophores
1988
Binding ofE. coliDNA photolyase to a defined substrate containing a single T< >T dimer
1987 StandoutNobel
A rapid DEAE disk assay for photoreactivation of pyrimidine dimers in [3H]DNA
1979
Absence of cancer–associated changes in human fibroblasts immortalized with telomerase
1999
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization
1998
Photoreactivating enzyme from Escherichia coli: appearance of new absorption on binding to ultraviolet irradiated DNA
1977
Identification of the second chromophore of Escherichia coli and yeast DNA photolyases as 5,10-methenyltetrahydrofolate.
1988 StandoutNobel
Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nuclease.
1985 StandoutNobel
Photolyases from Saccharomyces cerevisiae and Escherichia coli recognize common binding determinants in DNA containing pyrimidine dimers.
1989
Telomerase Activity Is Sufficient To Allow Transformed Cells To Escape from Crisis
1999
Action mechanism of Escherichia coli DNA photolyase. II. Role of the chromophores in catalysis.
1987 StandoutNobel
Identification of a neutral flavin radical and characterization of a second chromophore in Escherichia coli DNA photolyase
1984 StandoutNobel
Thermodynamics of the Photoenzymic Repair Mechanism Studied by Density Functional Theory
2000
Binding of T4 endonuclease V to deoxyribonucleic acid irradiated with ultraviolet light
1980
Deoxyribonucleic Acid Photoreactivating Enzyme from Escherichia coli
1973
Spontaneous In Vitro Immortalization of Breast Epithelial Cells from a Patient with Li-Fraumeni Syndrome
1995
Bypass of Senescence After Disruption of p21 CIP1/WAF1 Gene in Normal Diploid Human Fibroblasts
1997 Science
Mitochondrial D-loop sequences are integrated in the rat nuclear genome†
1991
Crystal Structure of DNA Photolyase from Escherichia coli
1995 StandoutScienceNobel
Action mechanism of Escherichia coli DNA photolyase. III. Photolysis of the enzyme-substrate complex and the absolute action spectrum.
1987 StandoutNobel
Subunit interaction and enzymic activity of mouse 7S nerve growth factor
1969
Binding of Escherichia coli DNA photolyase to UV-irradiated DNA
1985 StandoutNobel
Purification of the photoreactivating enzyme from yeast
1979
Structure and function of DNA photolyases
1987 StandoutNobel
Photoreactivation of Bacteriophage ϕX174
1975
SUBSTRATE DEPENDENCE OF THE ACTION SPECTRUM FOR PHOTOENZYMATIC REPAIR OF DNA
1976
Escherichia coli photoreactivating enzyme: purification and properties
1980
Developmental and tissue-specific regulation of mouse telomerase and telomere length.
1995 StandoutNobel
Identification of oligothymidylates as new simple substrates for E. coli DNA photolyase and their use in a rapid spectrophotometric enzyme assay
1985 StandoutNobel
Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae
1988
New class of enzymes acting on damaged DNA
1976 StandoutNatureNobel
Sequences of the Escherichia coli photolyase gene and protein.
1984 StandoutNobel
Purification of the yeast PHR1 photolyase from an Escherichia coli overproducing strain and characterization of the intrinsic chromophores of the enzyme.
1987
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
The RNA Component of Human Telomerase
1995 StandoutScienceNobel
Molecular Analyses of Oral Polio Vaccine Samples
2001 StandoutScienceNobel
Action mechanism of Escherichia coli DNA photolyase. I. Formation of the enzyme-substrate complex.
1987 StandoutNobel
PHOTOREACTIVATING ENZYME FROM Streptomyces griseus—VI. ACTION SPECTRUM AND KINETICS OF PHOTOREACTIVATION
1986
Deoxyribonucleic acid photoreactivating enzyme. Quantitative chemical assay and estimation of molecular weight of the yeast enzyme
1972
7-Methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection.
1988
Multiple mechanisms of N-(phosphonoacetyl)-L-aspartate drug resistance in SV40-infected precrisis human fibroblasts.
1993
Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells.
1994
A nuclear 'fossil' of the mitochondrial D-loop and the origin of modern humans
1995 StandoutNatureNobel
The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein
1999 StandoutNobel
Identification and amplification of theE. coli phrgene product
1983 StandoutNobel
DNA photoreactivating enzyme from placental mammals. Origin and characteristics
1974
Embryonic Stem Cell Lines Derived from Human Blastocysts
1998 StandoutScience
p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts.
1991
Structure and Function of DNA Photolyase and Cryptochrome Blue-Light Photoreceptors
2003 StandoutNobel
An Endonuclease from Escherichia coli That Acts Preferentially on UV-Irradiated DNA and Is Absent from the uvrA and uvrB Mutants
1974
Works of Harold Werbin being referenced
Toward a molecular understanding of human breast cancer: A hypothesis
1993
Telomerase Assays in the Diagnosis and Prognosis of Cancer
2007
Cellular and molecular advances in elucidating p53 function
1992
New evidence for the insertion of mitochondrial DNA into the human genome: significance for cancer and aging
1992
LOSS OF TELOMERIC DNA DURING AGING MAY PREDISPOSE CELLS TO CANCER (REVIEW)
1993
PRESENCE OF PHOTOREACTIVATING ENZYME IN BLUE‐GREEN ALGAL CELLS*
1968
Loss of the 4-β hydrogen in the conversion of [4-β-3H] cholesterol to cortisol by the guinea-pig adrenal gland homogenate
1963
Trypsin Hydrolysis of Lysine Ethyl Ester
1951
Defining the molecular mechanisms of human cell immortalization
1991
Photoreactivation of UV-irradiated blue-green algal virus LPP-1
1967
A RAPID ASSAY FOR DNA PHOTOLYASE USING A MEMBRANE‐BINDING TECHNIQUE*
1973
Action spectrum for a DNA-photoreactivating enzyme isolated from higher plants
1969
Evidence that deoxyribonucleic acid photolyase from bakers' yeast is a flavoprotein
1980
You Haven't Heard the End of It: Telomere Loss May Link Human Aging with Cancer
1995
THE SUBUNIT STRUCTURE OF YEAST DNA PHOTOLYASE AND THE PURIFICATION OF A FLUORESCENT ACTIVATOR OF THE ENZYME
1977
Telomeres and telomerase in human leukemias.
1996
Purification of a blue-green algal deoxyribonucleic acid photoreactivating enzyme. An enzyme requiring light as a physical cofactor to perform its catalytic function
1970
Yeast DNA photolyase. Molecular weight, subunit structure, and reconstitution of active enzyme from its subunits
1975
Spectral properties of the chromophoric material associated with the deoxyribonucleic acid photoreactivating enzyme isolated from baker's yeast
1971
Use of the membrane binding technique to study the kinetics of yeast deoxyribonucleic acid photolyase reactions. Formation of enzyme-substrate complexes in the dark and their photolysis
1974
Purification of an inhibitor of DNA photolyase with fluorescent spectra similar to those of the enzyme
1975
EVIDENCE FOR A DNA‐PHOTOREACTIVATING ENZYME IN HIGHER PLANTS
1969
Mitochondrial DNA copy number is proportional to total cell DNA under a variety of growth conditions.
1990
EXCITATION AND FLUORESCENCE SPECTRA OF THE CHROMOPHORE ASSOCIATED WITH THE DNA‐PHOTOREACTIVATING ENZYME FROM THE BLUE–GREEN ALGA ANACYSTIS NIDULANS
1972
Are mitochondrial DNA mutations involved in the carcinogenic process?
1987