Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction
2010 StandoutScienceNobel
Linkage Map ofEscherichia coliK-12, Edition 10: The Traditional Map
1998
An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells
2015 StandoutNobel
Synthesis of chemically modified cyclodextrins
1983
Effective combination of ET-743 and doxorubicin in sarcoma: preclinical studies
2003
Ecteinascidin 743: a novel anticancer drug with a unique mechanism of action
2002
Strong and Reversible Binding of Carbon Dioxide in a Green Metal–Organic Framework
2011 StandoutNobel
Recent advances in the catalytic asymmetric synthesis of β-amino acids
2010 StandoutNobel
Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
2006 StandoutNobel
DNA and its associated processes as targets for cancer therapy
2002
Functional Interplay between the Jaw Domain of Bacterial RNA Polymerase and Allele-specific Residues in the Product RNA-binding Pocket
2005
Modular click chemistry libraries for functional screens using a diazotizing reagent
2019 StandoutNatureNobel
Catalytic Three‐Component Ugi Reaction
2008 StandoutNobel
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Differential Block of Sensory Neuronal Voltage-Gated Sodium Channels by Lacosamide [(2 R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide], Lidocaine, and Carbamazepine
2008
The combination of yondelis and cisplatin is synergistic against human tumor xenografts
2003
Asymmetric Disulfonimide‐Catalyzed Synthesis of δ‐Amino‐β‐Ketoester Derivatives by Vinylogous Mukaiyama–Mannich Reactions
2014 StandoutNobel
Drug development from marine natural products
2008 Standout
Best Practices for QSAR Model Development, Validation, and Exploitation
2010
The NaV1.7 sodium channel: from molecule to man
2012
Opportunities and challenges in phenotypic drug discovery: an industry perspective
2017
Machine learning for molecular and materials science
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Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein
2010 StandoutNobel
Rapid removal of organic micropollutants from water by a porous β-cyclodextrin polymer
2015 StandoutNature
The mitomycin bioreductive antitumor agents: Cross-linking and alkylation of DNA as the molecular basis of their activity
1997
Nanoporous Carbohydrate Metal–Organic Frameworks
2011 StandoutNobel
Human Transcription Release Factor 2 Dissociates RNA Polymerases I and II Stalled at a Cyclobutane Thymine Dimer
1999 StandoutNobel
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Molecular Reactors and Machines: Applications, Potential, and Limitations
2004
Mechanisms of drug combinations: interaction and network perspectives
2009 Standout
A Simple Enantioconvergent and Chemoenzymatic Synthesis of Optically Active α‐Substituted Amides
2011 StandoutNobel
Phosphoramidites: Privileged Ligands in Asymmetric Catalysis
2010 StandoutNobel
DNA Structural Similarity in the 2:1 Complexes of the Antitumor Drugs Trabectedin (Yondelis) and Chromomycin A3 with an Oligonucleotide Sequence Containing Two Adjacent TGG Binding Sites on Opposing Strands
2005
Comparison of sequence preference of tomaymycin- and anthramycin-DNA bonding by exonuclease III and .lambda. exonuclease digestion and UvrABC nuclease incision analysis
1993
Human DNA Damage Checkpoint Protein hRAD9 Is a 3′ to 5′ Exonuclease
2000 StandoutNobel
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
Organocatalytic Enantioselective Aziridination of α,β‐Unsaturated Aldehydes
2006
In vivo 3′-to-5′ exoribonuclease targetomes of Streptococcus pyogenes
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Catalytic Asymmetric Additions of Enol Silanes to In Situ Generated Cyclic, AliphaticN‐Acyliminium Ions
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Marine Natural Products and Related Compounds in Clinical and Advanced Preclinical Trials
2004
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
The asymmetric synthesis of aziridines
1997
Convergent stereocontrolled construction of 5-7-6 tricyclic aza analogues of phorbol and aconite alkaloids
1995
Pillar[5]arene as a Co-Factor in Templating Rotaxane Formation
2013 StandoutNobel
Catalytic asymmetric addition of diorganozinc reagents to N -phosphinoylalkylimines
2004
Supramolecular Chemistry: Receptors, Catalysts, and Carriers
1985 StandoutScienceNobel
Inclusion compounds ?Past, present, and future
1983
An Asymmetric Synthesis of Aza Analogues of the Tricyclic Skeleton of Daphnane and the ABC Ring System of Phorbol
2002
Chemical Glycobiology
2001 StandoutScienceNobel
Deracemization of α-Aryl Hydrocoumarins via Catalytic Asymmetric Protonation of Ketene Dithioacetals
2012 StandoutNobel
The anticonvulsant activities of N-benzyl 3-methoxypropionamides
1999
Development of a New Photochromic Ion Channel Blocker via Azologization of Fomocaine
2014
Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo- and Stereoselective Hydrogenation of Ketones
2001 StandoutNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Synthetic Cyclic Oligosaccharides
1998 StandoutNobel
Block Copolymer Lithography: Periodic Arrays of ~10 11 Holes in 1 Square Centimeter
1997 StandoutScience
Prokaryotic Nucleotide Excision Repair: The UvrABC System
2006
Cyclodextrin-Based Catenanes and Rotaxanes
1998 StandoutNobel
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Biomimetic Reactions Catalyzed by Cyclodextrins and Their Derivatives
1998
Chemical synthesis gets a fillip from molecular recognition and self-assembly processes
2002 StandoutNobel
Structure of the Mycobacterium tuberculosis d -Alanine: d -Alanine Ligase, a Target of the Antituberculosis Drug d -Cycloserine
2010
Artificial Molecular Machines
2000 StandoutNobel
rho Is Not Essential for Viability or Virulence in Staphylococcus aureus
2001
A Redox-Switchable α-Cyclodextrin-Based [2]Rotaxane
2008 StandoutNobel
Enantioselective Synthesis of Tryptophan Derivatives by a Tandem Friedel–Crafts Conjugate Addition/Asymmetric Protonation Reaction
2012
Synthesis and Biological Evaluations of New Pyrrolo[2,3-b]pyrimidine as SDI Analogs
2008
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Catalytic Enantioselective Addition of Organometallic Reagents to N-Formylimines Using Monodentate Phosphoramidite Ligands
2008 StandoutNobel
Die Chemie vicinaler Diamine
1998
Biomimetic Chemistry and Artificial Enzymes: Catalysis by Design
1995
Cyclizations of N-Acyliminium Ions
2004 Standout
Synthesis of β-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase
2016 StandoutNobel
Modulation of Receptor and Receptor Subtype Affinities Using Diastereomeric and Enantiomeric Monosaccharide Scaffolds as a Means to Structural and Biological Diversity. A New Route to Ether Synthesis
1998
Role of the C-10 Substituent in Mitomycin C-1−DNA Bonding
1996
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Bromine-Catalyzed Aziridination of Olefins. A Rare Example of Atom-Transfer Redox Catalysis by a Main Group Element
1998 StandoutNobel
Pharmacology of the Na v 1.1 domain IV voltage sensor reveals coupling between inactivation gating processes
2017 StandoutNobel
Nav1.1 Modulation by a Novel Triazole Compound Attenuates Epileptic Seizures in Rodents
2014
Determination of some physical constants of cyclodextrin complexes by electrochemical methods
1984
Structure−Activity Relationship Study of First Selective Inhibitor of Excitatory Amino Acid Transporter Subtype 1: 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101)
2010
Emerging Targets in Photopharmacology
2016 StandoutNobel
Environmental applications of water-insoluble β-cyclodextrin–epichlorohydrin polymers
2012
Solid-Phase Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries
2000
Acid-Free, Aminoborane-Mediated Ugi-Type Reaction Leading to General Utilization of Secondary Amines
2007
A Solid-Phase Approach to Mouse Melanocortin Receptor Agonists Derived from a Novel Thioether Cyclized Peptidomimetic Scaffold
2002 StandoutNobel
Sulfamic Acid and Its N- and O-Substituted Derivatives
2013
Cyclodextrin chemistry. Selective modification of all primary hydroxyl groups of α‐ and β‐cyclodextrins
1978 StandoutNobel
Identification of a Potent Heterocyclic Ligand To Somatostatin Receptor Subtype 5 by the Synthesis and Screening of β-Turn Mimetic Libraries
1999
A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
2017 StandoutNobel
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
2011 StandoutNobel
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Works of Harold Kohn being referenced
Marked stereospecificity in a new class of anticonvulsants
1988
The anticonvulsant activities of functionalized N-benzyl 2-acetamidoacetamides. The importance of the 2-acetamido substituent
1996
Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives
2008
Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy
2007
Anticonvulsant Properties ofN‐Substituted α,α‐Diamino Acid Derivatives
1994
Preparation and anticonvulsant activity of a series of functionalized .alpha.-aromatic and .alpha.-heteroaromatic amino acids
1990
Synthesis and Anticonvulsant Activities of .alpha.-Acetamido-N-benzylacetamide Derivatives Containing an Electron-Deficient .alpha.-Heteroaromatic Substituent
1994
Transcription termination factor rho: The site of bicyclomycin inhibition in Escherichia coli
1993
The Antibiotic Bicyclomycin Affects the Secondary RNA Binding Site of Escherichia coli Transcription Termination Factor Rho
1996
N-Substituted amino acid N′-benzylamides: synthesis, anticonvulsant, and metabolic activities
2004
Synthesis and anticonvulsant activities of .alpha.-heterocyclic .alpha.-acetamido-N-benzylacetamide derivatives
1993
The inefficiency of incisions of ecteinascidin 743–DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent
2001
Preparation and anticonvulsant activity of a series of functionalized .alpha.-heteroatom-substituted amino acids
1991
A Novel Automated Lazy Learning QSAR (ALL-QSAR) Approach: Method Development, Applications, and Virtual Screening of Chemical Databases Using Validated ALL-QSAR Models
2006
The 1.9 Å Crystal Structure of Alanine Racemase from Mycobacterium tuberculosis Contains a Conserved Entryway into the Active Site,
2005
Studies on the bonding specificity for mitomycin C-DNA monoalkylation processes
1991
Synthesis and Anticonvulsant Activities of N-Benzyl-2-acetamidopropionamide Derivatives
1996
7-N-(Mercaptoalkyl)mitomycins: Implications of Cyclization for Drug Function
2002
C5 Cytosine Methylation at CpG Sites Enhances Sequence Selectivity of Mitomycin C−DNA Bonding
2000
3-Oxo- and 3-imino-4-substituted-1,2,5-thiadiazolidine 1,1-dioxides: synthesis, spectral properties, and selected chemistry
1989
Studies on the mechanism of activation of C(7) ethylenediamine substituted mitomycins. Relevance to the proposed mode of action of BMY-25067 and KW-2149
1996
Methylated cyclodextrin and a cyclodextrin polymer as catalysts in selective anisole chlorination
1976
Intramolecular N-carbamoyliminium ion cyclizations of unactivated alkenes and acetylenes
1984
Synthetic Enantiopure Aziridinomitosenes: Preparation, Reactivity, and DNA Alkylation Studies
2003
Development and Characterization of Novel Derivatives of the Antiepileptic Drug Lacosamide That Exhibit Far Greater Enhancement in Slow Inactivation of Voltage-Gated Sodium Channels
2010
On the origins of the DNA sequence selectivity of mitomycin monoalkylation transformations
1992
Synthesis and anticonvulsant activities of (R)-(O)-methylserine derivatives
1998
Quantitative Structure−Activity Relationship Analysis of Functionalized Amino Acid Anticonvulsant Agents Using k Nearest Neighbor and Simulated Annealing PLS Methods
2002
Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-Gated Sodium Channels and in the Treatment of Neuropathic Pain
2011
7-Aminoaziridinomitosenes: synthesis, structure, and chemistry
1991
Functionalized DL-amino acid derivatives. Potent new agents for the treatment of epilepsy
1987
Effect of Structural Modification of the Hydantoin Ring on Anticonvulsant Activity
1985
Synthesis of spiroimidazolidin-2-ones via intramolecular N-carbamoyliminium ion cyclization reactions
1985
3,7-Bis(carbothoxy)perhydro-1,5,2,4,6,8-dithiatetrazocime 1,1,5,5-tetroxide. Synthesis, Structure and Chemistry
1988
Application of Predictive QSAR Models to Database Mining: Identification and Experimental Validation of Novel Anticonvulsant Compounds
2004
Stereoselective synthesis of vicinal diamines from alkenes and cyanamide
1985
Sodium dithionite-mediated mitomycin C reductive activation processes
1992
Synthesis of substituted 2-imidazolidinones and annelated hydantoins via amidoalkylation transformations
1984
New stereoselective method for the preparation of vicinal diamines from olefins and cyanamide
1983