Citation Impact
Citing Papers
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
2020 StandoutNobel
CRISPR–Cas9 Structures and Mechanisms
2017 StandoutNobel
Programmable RNA recognition using a CRISPR-associated Argonaute
2018 StandoutNobel
CRISPR/Cas9 in Genome Editing and Beyond
2016
Transient Ablation of Regulatory T cells Improves Antitumor Immunity in Colitis-Associated Colon Cancer
2014 StandoutNobel
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
2007 Standout
Machine learning predicts new anti-CRISPR proteins
2020 StandoutNobel
CRISPR-Cas orthologues and variants: optimizing the repertoire, specificity and delivery of genome engineering tools
2017
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage
2022 StandoutNobel
Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2
2019 StandoutNobel
CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing
2017 StandoutNobel
The CRISPR tool kit for genome editing and beyond
2018
CRISPy-web: An online resource to design sgRNAs for CRISPR applications
2016
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Investigation of associations between Piezo1 mechanoreceptor gain-of-function variants and glaucoma-related phenotypes in humans and mice
2020 StandoutNobel
Cancer in inflammatory bowel disease
2008
Catalytically Active Cas9 Mediates Transcriptional Interference to Facilitate Bacterial Virulence
2019 StandoutNobel
Guide RNA engineering for versatile Cas9 functionality
2016
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
2020 StandoutNobel
Role for epithelial dysregulation in early-onset colitis-associated colon cancer in Gi2-alpha−/− mice
2008 StandoutNobel
Lipid nanoparticles for mRNA delivery
2021 Standout
PSC-IBD: a unique form of inflammatory bowel disease associated with primary sclerosing cholangitis
2004
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
2017
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2020 Standout
Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications
2017
Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity
2016
Inflammatory bowel disease: clinical aspects and established and evolving therapies
2007 Standout
Ulcerative Colitis Practice Guidelines in Adults (Update): American College of Gastroenterology, Practice Parameters Committee
2004 Standout
Primary Sclerosing Cholangitis
2005
Ulcerative colitis
2002
Candidate Phyla Radiation Roizmanbacteria From Hot Springs Have Novel and Unexpectedly Abundant CRISPR-Cas Systems
2019 StandoutNobel
Key role of the REC lobe during CRISPR–Cas9 activation by ‘sensing’, ‘regulating’, and ‘locking’ the catalytic HNH domain
2018 StandoutNobel
Immunoglobulin G4–Associated Cholangitis: Clinical Profile and Response to Therapy
2008 Standout
Orthologous CRISPR–Cas9 enzymes for combinatorial genetic screens
2017
Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders
2017
CRISPR-Mediated Ophthalmic Genome Surgery
2017
Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells
2016
Clinical features and management of primary sclerosing Cholangitis
2008
Activation-Induced Cytidine Deaminase Links Between Inflammation and the Development of Colitis-Associated Colorectal Cancers
2008 StandoutNobel
The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells
2016
Ulcerative colitis
2012 Standout
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
Consensus Conference: Colorectal Cancer Screening and Surveillance in Inflammatory Bowel Disease
2005
In vivo Editing of the Human Mutant Rhodopsin Gene by Electroporation of Plasmid-based CRISPR/Cas9 in the Mouse Retina
2016
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
Deciphering Off-Target Effects in CRISPR-Cas9 through Accelerated Molecular Dynamics
2019 StandoutNobel
Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches
2020 StandoutNobel
Ulcerative colitis
2016 Standout
Personalised genome editing – The future for corneal dystrophies
2018
Colorectal Cancer Prognosis Among Patients With Inflammatory Bowel Disease
2006
Adeno-associated virus vector as a platform for gene therapy delivery
2019 Standout
Diagnosis and management of dysplasia in patients with inflammatory bowel diseases
2004
A thermostable Cas9 with increased lifetime in human plasma
2017 StandoutNobel
Ulcerative colitis
2020 Standout
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Staphylococcus aureus Cas9 is a multiple-turnover enzyme
2018
Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis
2004
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Management of Crohn's Disease in Adults
2009 Standout
A Compact, High-Accuracy Cas9 with a Dinucleotide PAM for In Vivo Genome Editing
2018
Massively parallel kinetic profiling of natural and engineered CRISPR nucleases
2020 StandoutNobel
Infliximab for Induction and Maintenance Therapy for Ulcerative Colitis
2005 Standout
Genome-editing Technologies for Gene and Cell Therapy
2016
Amelioration of Alpha-1 Antitrypsin Deficiency Diseases with Genome Editing in Transgenic Mice
2018
Interventions for preventing posterior capsule opacification
2010
Epigenetics and Signaling Pathways in Glaucoma
2017
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
The chemistry of Cas9 and its CRISPR colleagues
2017 StandoutNobel
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
RNA-dependent RNA targeting by CRISPR-Cas9
2018 StandoutNobel
Stem cells in retinal regeneration: past, present and future
2013
Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases
2019
Cataracts
2017 Standout
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice
2016
CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens
2018 Standout
Biodegradable Amino-Ester Nanomaterials for Cas9 mRNA Delivery in Vitro and in Vivo
2017
antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline
2019 Standout
Works of Hari Jayaram being referenced
Increased colorectal neoplasia in chronic ulcerative colitis complicated by primary sclerosing cholangitis: fact or fiction?
2001
Posterior capsule opacification after implantation of a hydrophilic or a hydrophobic acrylic intraocular lens
2006
Fellow-eye comparison of posterior capsule opacification rates after implantation of 1CU accommodating and AcrySof MA30 monofocal intraocular lenses
2007
Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications
2015
Effect of 1-piece and 3-piece AcrySof intraocular lenses on the development of posterior capsule opacification after cataract surgery
2004
Effect of intraocular lens edge profile on posterior capsule opacification after extracapsular cataract surgery in a developing country
2007
MicroRNA Expression in the Glaucomatous Retina
2015
687. Therapeutic Correction of an LCA-Causing Splice Defect in the CEP290 Gene by CRISPR/Cas-Mediated Genome Editing
2015
124. Therapeutic Correction of an LCA-Causing Splice Defect in the CEP290 Gene by CRISPR/Cas-Mediated Gene Editing
2016
Human Müller Glia with Stem Cell Characteristics Differentiate into Retinal Ganglion Cell (RGC) Precursors In Vitro and Partially Restore RGC Function In Vivo Following Transplantation
2012