Citation Impact
Citing Papers
Regulation of nuclear-cytoplasmic partitioning by the lin-28 - lin-46 pathway reinforces microRNA repression of HBL-1 to confer robust cell-fate progression in C. elegans
2019 StandoutNobel
Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF
2009 StandoutNobel
HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O2 levels
2003 StandoutNobel
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
Treatment of kidney cancer
2009 StandoutNobel
Regulation of Multidrug Resistance-associated Protein 2 (ABCC2) by the Nuclear Receptors Pregnane X Receptor, Farnesoid X-activated Receptor, and Constitutive Androstane Receptor
2002
Mechanism of degradation of the steroid side chain in the formation of bile acids.
1992
1,25-Dihydroxyvitamin D3 is a negative endocrine regulator of the renin-angiotensin system
2002 Standout
24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver
1993
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
2008 StandoutNobel
Management of acute organophosphorus pesticide poisoning
2007 Standout
Activities of Recombinant Human Cytochrome P450c27 (CYP27) Which Produce Intermediates of Alternative Bile Acid Biosynthetic Pathways
1998
P450 Gene Induction by Structurally Diverse Xenochemicals: Central Role of Nuclear Receptors CAR, PXR, and PPAR
1999
Markedly Reduced Bile Acid Synthesis but Maintained Levels of Cholesterol and Vitamin D Metabolites in Mice with Disrupted Sterol 27-Hydroxylase Gene
1998
Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice
2014
Differential incorporation of cholesterol and cholesterol derivatives into ecdysteroids by the larval ring glands and adult ovaries of Drosophila melanogaster: a putative explanation for the l(3)ecd1 mutation
1996
Orphan Nuclear Receptors: The Exotics of Xenobiotics
2001
The Expression of the let-7 Small Regulatory RNA Is Controlled by Ecdysone during Metamorphosis in Drosophila melanogaster
2002 StandoutNobel
Porphyrias
2010 Standout
Oxysterols and atherosclerosis
1999
Oxygen sensing by HIF hydroxylases
2004 StandoutNobel
Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation
2001
Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression
2001 Nature
Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis
2000 Standout
Bioluminescence and chemiluminescence in drug screening
2003
Targeting multidrug resistance in cancer
2006 Standout
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
2013 StandoutNobel
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Pheromones and Nutritional Signals Regulate the Developmental Reliance on let-7 Family MicroRNAs in C. elegans
2019 StandoutNobel
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
Neutrophil extracellular traps in immunity and disease
2017 Standout
A cDNA Encoding a Rat Mitochondrial Cytochrome P450 Catalyzing Both the 26-Hydroxylation of Cholesterol and 25-Hydroxylation of Vitamin D 3 : Gonadotropic Regulation of the Cognate mRNA in Ovaries
1990
The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338
1998 Nature
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
2001 Standout
Interindividual Differences in Hepatic Expression of CYP3A4: Relationship to Genetic Polymorphism in the 5′-Upstream Regulatory Region
1999
Drugs Mediate the Transcriptional Activation of the 5-Aminolevulinic Acid Synthase (ALAS1) Gene via the Chicken Xenobiotic-sensing Nuclear Receptor (CXR)
2002
The hormone resistin links obesity to diabetes
2001 StandoutNature
Rho and Rac Take Center Stage
2004 Standout
Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and Broad-Complex gene activity
2003 StandoutNobel
The von Hippel–Lindau protein, HIF hydroxylation, and oxygen sensing
2005 StandoutNobel
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
The P450 Superfamily: Update on New Sequences, Gene Mapping, and Recommended Nomenclature
1991
The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation ofCYP3A4by Rifampicin through a Distal Enhancer Module
1999
Atherosclerosis
2001 Standout
Humanized xenobiotic response in mice expressing nuclear receptor SXR
2000 Nature
The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature
1993 Standout
Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis.
1991
Identification of Farnesoid X Receptor β as a Novel Mammalian Nuclear Receptor Sensing Lanosterol
2003 StandoutNobel
Biosynthesis of the Caenorhabditis elegans dauer pheromone
2009 StandoutNobel
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
The Enzymes, Regulation, and Genetics of Bile Acid Synthesis
2003 Standout
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
2001
PROLINE HYDROXYLATION AND GENE EXPRESSION
2005 StandoutNobel
A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans
2009 StandoutNobel
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Oxysterols: Modulators of Cholesterol Metabolism and Other Processes
2000
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids
2001
A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo
2009 StandoutNobel
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
2001
Polycyclic Polyprenylated Acylphloroglucinols
2006 Standout
BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis
2002
Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development inCaenorhabditis elegans
2008 StandoutNobel
The Human Nuclear Xenobiotic Receptor PXR: Structural Determinants of Directed Promiscuity
2001 Science
Intercellular signaling of reproductive development by theC. elegansDAF-9 cytochrome P450
2004 StandoutNobel
The PPARs: From Orphan Receptors to Drug Discovery
2000 Standout
Pentalenolactone Biosynthesis. Molecular Cloning and Assignment of Biochemical Function to PtlI, a Cytochrome P450 of Streptomyces avermitilis
2006 StandoutNobel
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
2009 StandoutScience
Electrogenerated Chemiluminescence and Its Biorelated Applications
2008 Standout
A Gene Cluster for Biosynthesis of the Sesquiterpenoid Antibiotic Pentalenolactone inStreptomyces avermitilis
2006 StandoutNobel
The von Hippel-Lindau Tumor Suppressor Protein and Clear Cell Renal Carcinoma
2007 StandoutNobel
Muscarinic Receptor Agonists and Antagonists
2001
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
2010 StandoutNobel
Orphan Nuclear Receptors: Shifting Endocrinology into Reverse
1999 Science
Herbal Modulation of P‐Glycoprotein
2004
Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes
2004 Standout
Current Understanding of the Molecular Actions of Vitamin D
1998
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Targeted ablation of the 25-hydroxyvitamin D 1α-hydroxylase enzyme: Evidence for skeletal, reproductive, and immune dysfunction
2001
Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity
2004 StandoutNobel
St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor
2000
daf-12encodes a nuclear receptor that regulates the dauer diapause and developmental age inC. elegans
2000
The Developmental Timing Regulatorhbl-1Modulates the Dauer Formation Decision inCaenorhabditis elegans
2010 StandoutNobel
Works of Hans Postlind being referenced
Characterization of the rabbit CYP1A1 and CYP1A2 genes: Developmental and dioxin-inducible expression of rabbit liver P4501A1 and P4501A2
1992
A possible role for CYP27 as a major renal mitochondrial 25‐hydroxyvitamin D3 1α‐hydroxylase
1996
Response of Human CYP1-Luciferase Plasmids to 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Polycyclic Aromatic Hydrocarbons
1993
Evidence for the formation of 26-hydroxycholesterol by cytochrome P-450 in pig kidney mitochondria
1989
Effects on CYP27 mRNA Expression in Rat Kidney and Liver by 1α,25-Dihydroxyvitamin D3, a Suppressor of Renal 25-Hydroxyvitamin D3 1α-Hydroxylase Activity
1995
Liver mitochondrial cytochrome P450 CYP27 and recombinant-expressed human CYP27 catalyze 1 alpha-hydroxylation of 25-hydroxyvitamin D3.
1994
Characterization of mitochondrial cytochromes P-450 from pig kidney and liver catalysing 26-hydroxylation of 25-hydroxyvitamin D3 and C27 steroids
1991
Introduction to in vitro estimation of metabolic stability and drug interactions of new chemical entities in drug discovery and development.
2007
Identification of a human nuclear receptor defines a new signaling pathway for CYP 3 A induction
1998
Tolterodine, a new muscarinic receptor antagonist, is metabolized by cytochromes P450 2D6 and 3A in human liver microsomes.
1998
Characterization of pig kidney microsomal cytochrome P-450 catalysing 25-hydroxylation of vitamin D3 and C27 steroids
1990
Biotransformation of tolterodine, a new muscarinic receptor antagonist, in mice, rats, and dogs.
1998