Citation Impact
Citing Papers
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Single-crystal x-ray diffraction structures of covalent organic frameworks
2018 StandoutScienceNobel
Cardiolipins and biomembrane function
1992
Production of Reactive Oxygen Species by Mitochondria
2003
Mitochondria and Ageing
1992
Frataxin is Reduced in Friedreich Ataxia Patients and is Associated with Mitochondrial Membranes
1997
Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans
2001
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Topology of Superoxide Production from Different Sites in the Mitochondrial Electron Transport Chain
2002 Standout
The free radical hypothesis of aging: An appraisal of the current status
1993
Hydrogen peroxide release by mitochondria increases during aging
1991
Role of oxidative stress in Drosophila aging
1992
Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies
1995
Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production
2008 Standout
Altered Protein Metabolism in Aging
1991
Homeostasis between lipid peroxidation and antioxidant enzyme activities in healthy human aging
1992
Aging and oxidative stress: Modulation by dietary restriction
1996
Oxidants and Skeletal Muscle Function: Physiologic and Pathophysiologic Implications
1999
Progressive loss of cytochrome c oxidase in the human extraocular muscles in ageing — a cytochemical-immunohistochemical study
1992
Alterations in mitochondrial membrane fluidity by lipid peroxidation products
1994
Reactive oxygen and DNA damage in mitochondria
1992
Lipid-soluble components in cigarette smoke induce mitochondrial production of reactive oxygen species in lung epithelial cells
2009
The effect of aging and acetyl-l-carnitine on the activity of the phosphate carrier and on the phospholipid composition in rat heart mitochondria
1992
Effect of aging on the activity of the phosphate carrier and on the lipid composition in rat liver mitochondria
1991
Aging‐ and Oxygen‐induced Modifications in Brain Biochemistry and Behaviora
1994
Age-related changes in antioxidant enzymes and prooxidant generation in tissues of the rat with special reference to parameters in two insect species
1990
Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon
1997
Lipid Composition in Synaptic and Nonsynaptic Mitochondria from Rat Brains and Effect of Aging
1992
Regulation of hypoxia adaptation: an overlooked virulence attribute of pathogenic fungi?
2010
Biochemical changes associated with the mechanism controlling superoxide radical formation in the aging rotifer
1990
Free‐Radical Theory of Aging
1994
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Biochemical Functions of Coenzyme Q10
2001
The production of reactive oxygen and nitrogen species by skeletal muscle
2006
Lack of recovery from oxygen-induced damage to colony formation and DNA synthesis in senescent human diploid fibroblasts
1987
Mitochondria, Oxidants, and Aging
2005 Standout
Free Radical Involvement in Aging
1993
Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species
1993
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Alpha-lipoic acid as a biological antioxidant
1995 Standout
Mitochondrial ROS Metabolism: Modulation by Uncoupling Proteins
2001
Dependence of H2O2 Formation by Rat Heart Mitochondria on Substrate Availability and Donor Age
1997
Evidence for and against the causal involvement of mitochondrial DNA mutation in mammalian ageing
1992
An age-related increase in the basal level of DNA damage and DNA vulnerability to oxygen radicals in the individual hepatocytes of male F344 rats
1994
Biochemical Mechanisms for Oxygen Free Radical Formation During Exercise
1990
Caloric restriction, aging, and antioxidant enzymes
1993
Mitochondrial DNA alterations as ageing-associated molecular events
1992
Antioxidant action of ubiquinol homologues with different isoprenoid chain length in biomembranes
1990
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Localization at Complex I and Mechanism of the Higher Free Radical Production of Brain Nonsynaptic Mitochondria in the Short-Lived Rat Than in the Longevous Pigeon
1998
Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging?
1990
The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron–sulfur cluster N2
2001
Free radical theory of aging
1992
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Oxidative damage to mitochondrial DNA shows marked age‐dependent increases in human brain
1993
Mitochondrial oxidative damage, hydrogen peroxide release, and aging
1994
Relationship between Antioxidants, Prooxidants, and the Aging Processa
1992
Nitric Oxide Acts Directly in the Presynaptic Neuron to Produce Long-Term Potentiationin Cultured Hippocampal Neurons
1996 StandoutNobel
Exercise at Old Age: Does It Increase or Alleviate Oxidative Stress?
2001
Decreased activity of the phosphate carrier and modification of lipids in cardiac mitochondria from senescent rats
1992
H2O2 production of heart mitochondria and aging rate are slower in canaries and parakeets than in mice: sites of free radical generation and mechanisms involved
1998
Systemic Inflammation and Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease: State of the Art and Novel Insights in Regulation of Muscle Plasticity
2007
Oxidants and antioxidants in proliferative senescence
1991
Uncoupling to survive? The role of mitochondrial inefficiency in ageing
2000
Targeting lipoic acid to mitochondria: Synthesis and characterization of a triphenylphosphonium-conjugated α-lipoyl derivative
2007
Complex III Releases Superoxide to Both Sides of the Inner Mitochondrial Membrane
2004
SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES
1995 Standout
ADP-Regulation of Mitochondrial Free Radical Production Is Different with Complex I- or Complex II-Linked Substrates: Implications for the Exercise Paradox and Brain Hypermetabolism
1997
Reduction of Ferrylmyoglobin and Ferrylhemoglobin by Nitric Oxide: A Protective Mechanism against Ferryl Hemoprotein-Induced Oxidations
1995
Mitochondrial Oxygen Radical Generation and Leak: Sites of Production in States 4 and 3, Organ Specificity, and Relation to Aging and Longevity
1999
Mitochondria in Exercise-Induced Oxidative Stress
2001
Free radical generation by skeletal muscle of adult and old mice: effect of contractile activity
2006
Hydrogen Peroxide: A Signaling Messenger
2006 Standout
The Free Radical Theory of Aging
2003
Oxidative damage and mitochondrial decay in aging.
1994 Standout
p-Nitrostilbene-tert-Butyl-Nitrone: a Novel Fluorescent Spin Trap for the Detection of ROS with Subcellular Resolution
2009
Cardiac reperfusion injury: Aging, lipid peroxidation, and mitochondrial dysfunction
1998
Membrane assembly in vitro : Synthesis, glycosylatio, and asymmetric insertion of a transmembrane protein
1977 StandoutNobel
Intra- and extracellular measurement of reactive oxygen species produced during heat stress in diaphragm muscle
2000
Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies.
1993 StandoutNobel
An activity in rat tissues that modifies nitrotyrosine-containing proteins
1998 StandoutNobel
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
1993 StandoutNobel
Endurance training reduces the susceptibility of mouse skeletal muscle to lipid peroxidation in vitro
1983
Detection of catalase in rat heart mitochondria.
1991
Regional mapping of prion proteins in brain.
1992 StandoutNobel
The Free Radical Theory of Aging Matures
1998 Standout
An octamer of histones in chromatin and free in solution.
1975 StandoutNobel
Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9
2002 StandoutNobel
Free Radicals as Mediators of Tissue Injury
1991
Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.
1985 StandoutNobel
Oxidative damage during aging targets mitochondrial aconitase
1997
Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype.
1988 StandoutNobel
Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family.
1991 StandoutNobel
Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins.
1987 StandoutNobel
Inactivation-reactivation of aconitase in Escherichia coli. A sensitive measure of superoxide radical.
1992
Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs.
1986 StandoutNobel
Role for Mitochondrial Oxidants as Regulators of Cellular Metabolism
2000
Age-related changes in the activity of the pyruvate carrier and in the lipid composition in rat-heart mitochondria
1990
Organization and expression of early genes of simian virus 40
1978 StandoutNobel
Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response.
1981 StandoutNobel
Is increased tissue ferritin a risk factor for atherosclerosis and ischaemic heart disease?
1995
A lamin B receptor in the nuclear envelope.
1988 StandoutNobel
Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis.
1980 StandoutNobel
Hyperoxia increases H2O2 release by lung mitochondria and microsomes
1982
Purification of the regulatory component of adenylate cyclase.
1980 StandoutNobel
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells.
1991 StandoutNobel
Aquaglyceroporin AQP9: Solute permeation and metabolic control of expression in liver
2003 StandoutNobel
Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor.
1986 StandoutNobel
Mitochondrial production of pro-oxidants and cellular senescence
1992
Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.
1994 StandoutNobel
Effect of electron transfer inhibitors on superoxide generation in the cytochrome bc1 site of the mitochondrial respiratory chain
1983
A cellular protein that associates with the transforming protein of Rous sarcoma virus is also a heat-shock protein.
1981 StandoutNobel
Chemodynamic Therapy: Tumour Microenvironment‐Mediated Fenton and Fenton‐like Reactions
2018 Standout
ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation.
1980 StandoutNobel
The aging process.
1981 Standout
cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.
1989 StandoutNobel
Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion‐induced necrosis and apoptosis in vivo
2000
Glutathione, oxidative stress and aging
1996
Hydrogen Peroxide is Scavenged by Ascorbate-specific Peroxidase in Spinach Chloroplasts
1981 Standout
Free Radicals in the Physiological Control of Cell Function
2002 Standout
REGULATION OF GENE EXPRESSION BY REACTIVE OXYGEN
1999
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Bioenergetics in aging
1983
Cloning immunoglobulin variable domains for expression by the polymerase chain reaction.
1989 StandoutNobel
Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses
1999 StandoutNobel
Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase.
1991 StandoutNobel
G protein gamma subunits contain a 20-carbon isoprenoid.
1990 StandoutNobel
Mitochondrial role in cell aging
1980
Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia
1999 StandoutNobel
Works of Hans Nohl being referenced
The existence and significance of a mitochondrial nitrite reductase
2005
Involvement of free radicals in ageing: a consequence or cause of senescence
1993
2,3,7,8 Tetrachlorodibenzo-P-dioxin induces oxygen activation associated with cell respiration
1989
Dihydrolipoic Acid Maintains Ubiquinone in the Antioxidant Active Form by Two-Electron Reduction of Ubiquinone and One-Electron Reduction of Ubisemiquinone
1999
Synthesis and Characterization of EMPO-Derived 5,5-Disubstituted 1-Pyrroline N-Oxides as Spin Traps Forming Exceptionally Stable Superoxide Spin Adducts
2003
Are mitochondria a spontaneous and permanent source of reactive oxygen species?
2003
Is Redox-Cycling Ubiquinone Involved In Mitochondrial Oxygen Activation?
1990
Are mitochondria a permanent source of reactive oxygen species?
2000
Conditions allowing redox-cycling ubisemiquinone in mitochondria to establish a direct redox couple with molecular oxygen
1996
Skeletal muscles, heart, and lung are the main sources of oxygen radicals in old rats
2004
The Ubiquinol/bc1 Redox Couple Regulates Mitochondrial Oxygen Radical Formation
2001
Imbalance of oxygen activation and energy metabolism as a consequence or mediator of aging
1997
Ischemia/Reperfusion Impairs Mitochondrial Energy Conservation and Triggers O2−Release as a Byproduct of Respiration
1993
Intracellular generation of reactive oxygen species by mitochondria
2005
Ubisemiquinones of the Mitochondrial Respiratory Chain Do not Interact with Molecular Oxygen
1992
The Existence of a Lysosomal Redox Chain and the Role of Ubiquinone
2000
Chemiluminescence from activated heme compounds detected in the reaction of various xenobiotics with oxyhemoglobin: Comparison with several heme/hydrogen peroxide systems
1993
H2O2 detection from intact mitochondria as a measure for one-electron reduction of dioxygen requires a non-invasive assay system11Dedicated to Prof. E. Elstner, on the occasion of his 60th anniversary.
1999
Activation of PPAR-δ in isolated rat skeletal muscle switches fuel preference from glucose to fatty acids
2006
Is oxidative stress primarily involved in reperfusion injury of the ischemic heart?
1991
Age-Dependent Changes in the Structure-Function Correlation of ADP/ATP-Translocating Mitochondrial Membranes
1982
The mitochondrial site of superoxide formation
1986
Responses of mitochondrial superoxide dismutase, catalase and glutathione peroxidase activities to aging
1979
The involvement of biological quinones in the formation of hydroxyl radicals via the Haber-Weiss reaction
1987
A novel superoxide radical generator in heart mitochondria
1987
Evidence for the existence of catalase in the matrix space of rat‐heart mitochondria
1978
OH•-generation by adriamycin semiquinone and H2O2; An explanation for the cardiotoxicity of anthracycline antibiotics
1983
Mitochondria recycle nitrite back to the bioregulator nitric monoxide.
2000
The Metabolic Fate of Mitochondrial Hydrogen Peroxide
1980
Do Mitochondria Produce Oxygen Radicals in vivo?
1978
Molecular basis of age-dependent changes in the activity of adenine nucleotide translocase
1980
Influence of age on thermotropic kinetics of enzymes involved in mitochondrial energy-metabolism.
1979
Generation of superoxide radicals as byproduct of cellular respiration.
1994
Influence of Mitochondrial Radical Formation on Energy‐Linked Respiration
1978
Identification of free hydroxyl radicals in respiring rat heart mitochondria by spin trapping with the nitrone DMPO
1981
The mechanism of toxic action of hyperbaric oxygenation on the mitochondria of rat-heart cells
1981