Citation Impact
Citing Papers
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
CRISPR/Cas9 in Genome Editing and Beyond
2016
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Rationally engineered Cas9 nucleases with improved specificity
2015 StandoutScience
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage
2022 StandoutNobel
Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2
2019 StandoutNobel
The CRISPR tool kit for genome editing and beyond
2018
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED
2015 StandoutNobel
Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria
2020
How specific is CRISPR/Cas9 really?
2015
dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
2022 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
2015 Standout
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
2016 StandoutNature
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
2015
Complex transcriptional modulation with orthogonal and inducible dCas9 regulators
2016
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
2014 Standout
Classification and evolution of type II CRISPR-Cas systems
2014 StandoutNobel
Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators
2015
Post-translational Regulation of Cas9 during G1 Enhances Homology-Directed Repair
2016
A CRISPR–dCas Toolbox for Genetic Engineering and Synthetic Biology
2018
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
NmeCas9 is an intrinsically high-fidelity genome-editing platform
2018
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Enabling functional genomics with genome engineering
2015
The Human Transcription Factors
2018 Standout
Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9
2016
Applications of CRISPR–Cas systems in neuroscience
2015
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
Inhibition of CRISPR-Cas systems by mobile genetic elements
2017
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
Massively parallel determination and modeling of endonuclease substrate specificity
2014 StandoutNobel
Programmable RNA recognition and cleavage by CRISPR/Cas9
2014 StandoutNatureNobel
CRISPR/Cas9-Based Engineering of the Epigenome
2017
Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation
2015
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Development and Applications of CRISPR-Cas9 for Genome Engineering
2014 Standout
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity
2016
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
A thermostable Cas9 with increased lifetime in human plasma
2017 StandoutNobel
The next generation of CRISPR–Cas technologies and applications
2019
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Absence of a simple code: how transcription factors read the genome
2014
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA
2016
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome
2017
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
2017 StandoutNobel
Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9
2016 StandoutNobel
Persistent Alterations in Microglial Enhancers in a Model of Chronic Pain
2016
CRISPR/Cas9-Mediated Genome Editing of Epigenetic Factors for Cancer Therapy
2015
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems
2016 Science
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
Conservation of transcription factor binding specificities across 600 million years of bilateria evolution
2015
CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine
2017
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
2015 StandoutScienceNobel
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference
2014 StandoutNobel
Rational design of a split-Cas9 enzyme complex
2015 StandoutNobel
Phage-Encoded Anti-CRISPR Defenses
2018
Overview of guide RNA design tools for CRISPR-Cas9 genome editing technology
2015
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Nucleosomes impede Cas9 access to DNA in vivo and in vitro
2016
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Hannah Pham being referenced
Widespread evidence of cooperative DNA binding by transcription factors in Drosophila development
2013
Global analysis of Drosophila Cys2-His2 zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants
2013
Functional annotation of native enhancers with a Cas9–histone demethylase fusion
2015
Computational Identification of Diverse Mechanisms Underlying Transcription Factor-DNA Occupancy
2013
Ligand-gated diffusion across the bacterial outer membrane
2011