Citation Impact
Citing Papers
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
Copper-free click chemistry in living animals
2010 StandoutNobel
Hydrogen peroxide sensing, signaling and regulation of transcription factors
2014
Potential Mechanisms for a Proinflammatory Vascular Cytokine Response to Coagulation Activation
1998
Characterization of Insulin-Like Growth Factor (IGF)-I-Receptor Binding Sites during In Vitro Transformation of Rat Hepatic Stellate Cells to Myofibroblasts
1996
Insulin-Like Growth Factor 2 in Development and Disease: A Mini-Review
2012
Transforming growth factor-beta2 antibody attenuates fibrosis in the experimental diabetic rat kidney
2001
α2‐Macroglobulin reduces paracrine‐ and autocrine‐stimulated matrix synthesis of cultured rat hepatic stellate cells
1999
Vascular NADPH oxidases: molecular mechanisms of activation
2004
Signal transduction via platelet-derived growth factor receptors
1998
Spironolactone exhibits direct renoprotective effects and inhibits renal renin–angiotensin–aldosterone system in diabetic rats
2008
Pathophysiology of Progressive Nephropathies
1998 Standout
The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C1 1The authors thank Wanda Delogu and Nadia Navari for skillful technical help, Dr. Roberto G. Romanelli for help in collecting liver biopsy specimens, and Dr. Mario Strazzabosco (Ospedali Riuniti di Bergamo, Italy) for providing part of the tissue samples with primary biliary cirrhosis.
2003
Expression of functionally phagocyte‐type NAD(P)H oxidase in pericytes: effect of angiotensin II and high glucose
2005
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
PDGF and signal transduction in hepatic stellate cells
2002
Interplay of Sp1 and Egr-1 in the Proximal Platelet-derived Growth Factor A-Chain Promoter in Cultured Vascular Endothelial Cells
1995
Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture.
1994
Chemokines and leukocyte traffic
1998 StandoutNature
Transforming growth factor-β1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells
2005
Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes
2012
Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1, and the monocyte colony-stimulating factor, CSF-1, in response to tumor necrosis factor-alpha and immunoglobulin G. Evidence for involvement of reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase.
1993
Stepwise renal lineage differentiation of mouse embryonic stem cells tracing in vivo development
2011
Mechanisms of liver fibrosis
2005
Roles of connective tissue growth factor and prostanoids in early streptozotocin-induced diabetic rat kidney: the effect of aspirin treatment
2003
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Renal activity of Akt kinase in experimental Type 1 diabetes
2008
NOX4 as an oxygen sensor to regulate TASK-1 activity
2005
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
ERK5 differentially regulates PDGF-induced proliferation and migration of hepatic stellate cells
2007
Up-regulation of glomerular COX-2 by angiotensin II: Role of reactive oxygen species
2005
PAR1 antagonism protects against experimental liver fibrosis. Role of proteinase receptors in stellate cell activation
2004
Expression of the thrombin receptor in human liver: Up-regulation during acute and chronic injury
1998
Expression of platelet-derived growth factor receptors in normal and diseased human kidney. An immunohistochemistry and in situ hybridization study.
1994
Ncf1 (p47phox) Is Essential for Direct Regulatory T Cell Mediated Suppression of CD4+ Effector T Cells
2011
Increased expression of TGF-β1 mRNA in the obstructed kidney of rats with unilateral ureteral ligation
1993
Angiotensin-(1–7) Prevents Activation of NADPH Oxidase and Renal Vascular Dysfunction in Diabetic Hypertensive Rats
2007
Advanced Glycation End Product-induced Apoptosis and Overexpression of Vascular Endothelial Growth Factor and Monocyte Chemoattractant Protein-1 in Human-cultured Mesangial Cells
2002
High glucose alters the response of mesangial cell protein kinase C isoforms to endothelin-1
1999
Cardiovascular risk continuum: implications of insulin resistance and diabetes
1998
Involvement of chemokine receptors in breast cancer metastasis
2001 StandoutNature
Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury
2008
Transcriptional Profiling Reveals Novel Markers of Liver Fibrogenesis
2006
Neuronal expression of the NADPH oxidase NOX4, and its regulation in mouse experimental brain ischemia
2005
Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells
2006
A crucial function of PDGF in TGF-β-mediated cancer progression of hepatocytes
2006
Peroxisome proliferator-activated receptor γ transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells
2000
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Chronic kidney disease
2011 Standout
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
In Vivo Maturation of Functional Renal Organoids Formed from Embryonic Cell Suspensions
2012
Thrombin signalling and protease-activated receptors
2000 StandoutNature
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
2012 Standout
Pigment epithelium-derived factor (PEDF) blocks angiotensin II signaling in endothelial cells via suppression of NADPH oxidase: a novel anti-oxidative mechanism of PEDF
2005
Modulation of transcription factor function by O-GlcNAc modification
2010
Role of Platelet-Derived Growth Factor in Renal Injury
1995
Signals controlling the expression of PDGF
1996
Genomic and functional characterization of stellate cells isolated from human cirrhotic livers
2005
Antisense strategy against PDGF B-chain proves effective in preventing experimental liver fibrogenesis
2004
Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling
2011
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Thrombin inhibits migration of human hepatic myofibroblasts
2007
The Nox Family of NAD(P)H Oxidases: Host Defense and Beyond
2004
H2O2 activates Nox4 through PLA2‐dependent arachidonic acid production in adult cardiac fibroblasts
2005
Mechanisms of Hepatic Fibrogenesis
2008 Standout
Adiponectin regulates albuminuria and podocyte function in mice
2008
The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine
2009
Metabolic Regulation by p53 Family Members
2013
Nox proteins in signal transduction
2009
Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells
1996
The superoxide‐producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells
2005
Molecular composition and regulation of the Nox family NAD(P)H oxidases
2005
Bone Marrow Is a Reservoir of Repopulating Mesangial Cells during Glomerular Remodeling
2001
The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma
2019
Chemokines and their role in tumor growth and metastasis
1998
Reactive oxygen species amplify glucose signalling in renal cells cultured under high glucose and in diabetic kidney
2005
Ligands of peroxisome proliferator-activated receptor γ modulate profibrogenic and proinflammatory actions in hepatic stellate cells
2000
Chemopreventive agents induce programmed death-1-ligand 1 (PD-L1) surface expression in breast cancer cells and promote PD-L1-mediated T cell apoptosis
2007
Structure and mechanism of a bacterial β-glucosaminidase having O-GlcNAcase activity
2006
Activation of nuclear factor-κB correlates with MCP-1 expression by human mesangial cells
1995
Overexpression of glucose transporters in rat mesangial cells cultured in a normal glucose milieu mimics the diabetic phenotype.
1995
The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle
2004
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Transforming Growth Factor β in Tissue Fibrosis
1994 Standout
Emerging role of Akt kinase/protein kinase B signaling in pathophysiology of diabetes and its complications
2005
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
2011
Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice
2006
Endothelin antagonism in experimental hepatic fibrosis. Implications for endothelin in the pathogenesis of wound healing.
1996
Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases
2005
In Vitro Migratory Potential of Rat Quiescent Hepatic Stellate Cells and Its Augmentation by Cell Activation
1999
Cytochrome P450: major player in reperfusion injury
2003
Hexosamines, insulin resistance, and the complications of diabetes: current status
2005
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
ROCK Inhibitor Y-27632 Attenuates Stellate Cell Contraction and Portal Pressure Increase Induced by Endothelin-1
1999
Activation of rat liver perisinusoidal lipocytes by transforming growth factors derived from myofibroblastlike cells. A potential mechanism of self perpetuation in liver fibrogenesis.
1992
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Pericytes regulate the blood–brain barrier
2010 StandoutNature
Cycling of O-linked β-N-acetylglucosamine on nucleocytoplasmic proteins
2007 Nature
Type I, II, III, IV, V, and VI Collagens Serve as Extracellular Ligands for the Isoforms of Platelet-derived Growth Factor (AA, BB, and AB)
1996
Liver fibrosis: searching for cell model answers
2007
Type IV Collagen and Laminin Regulate Glomerular Mesangial Cell Susceptibility to Apoptosis Via β1 Integrin-Mediated Survival Signals
1999
Suppression of transforming growth factor beta and vascular endothelial growth factor in diabetic nephropathy in rats by a novel advanced glycation end product inhibitor, OPB-9195
1999
Infusion of platelet-derived growth factor or basic fibroblast growth factor induces selective glomerular mesangial cell proliferation and matrix accumulation in rats.
1993
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Platelet-derived growth factor plays a critical role to convert bone marrow cells into glomerular mesangial-like cells
2003 StandoutNobel
Suppression Subtractive Hybridization Identifies High Glucose Levels as a Stimulus for Expression of Connective Tissue Growth Factor and Other Genes in Human Mesangial Cells
1999
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
2011 StandoutNature
Attenuation of diabetic nephropathy in diabetes rats induced by streptozotocin by regulating the endoplasmic reticulum stress inflammatory response
2010
Effects of renin–angiotensin system blockade in the aging kidney
2003
PDGF and TGF-β contribute to the natural course of human IgA glomerulonephritis
1995
Fibrogenic cell fate during fibrotic tissue remodelling observed in rat and human cultured liver slices
2006
Ablation of the gene encoding p66Shc protects mice against AGE-induced glomerulopathy by preventing oxidant-dependent tissue injury and further AGE accumulation
2007
Modulation of neutrophil influx in glomerulonephritis in the rat with anti-macrophage inflammatory protein-2 (MIP-2) antibody.
1995
Developmental patterns of PDGF B-chain, PDGF-receptor, and α-actin expression in human glomerulogenesis
1992
Cross talk between mitochondria and NADPH oxidases
2011
TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN
2009
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis
1999
NADPH Oxidases in the Kidney
2006
Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.
1994 Standout
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
2001 StandoutScience
First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
2010
Growth Inhibition and Apoptosis in Liver Myofibroblasts Promoted by Hepatocyte Growth Factor Leads to Resolution from Liver Cirrhosis
2005
Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors
2001
The Hexosamine Signaling Pathway: Deciphering the "O-GlcNAc Code"
2005
Metabolic cross-talk allows labeling of O-linked β- N -acetylglucosamine-modified proteins via the N -acetylgalactosamine salvage pathway
2011 StandoutNobel
Modulatory effects of HMG‐CoA reductase inhibitors in diabetic microangiopathy
2004
Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma
2005
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Nitric oxide down‐regulates the expression of the catalytic NADPH oxidase subunit Nox1 in rat renal mesangial cells
2005
Inhibition of T cell recruitment and cutaneous delayed-type hypersensitivity-induced inflammation with antibodies to monocyte chemoattractant protein-1.
1996
Insulinlike growth factor—ii/mannose 6-phosphate receptor is expressed on ccl4-exposed rat fat-storing cells and facilitates activation of latent transforming growth factor-β in cocultures with sinusoidal endothelial cells
1995
The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae
2000 StandoutNobel
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Induction of monocyte chemoattractant protein-1 in proximal tubule cells by urinary protein.
1997
Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes
2008
Molecular dissection of the mitogenic effect of hepatocytes on cultured hepatic stellate cells
1995
From Hyperglycemia to Diabetic Kidney Disease: The Role of Metabolic, Hemodynamic, Intracellular Factors and Growth Factors/Cytokines
2004
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
1997 StandoutNobel
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Wound Healing--Aiming for Perfect Skin Regeneration
1997 StandoutScience
Multistep Navigation and the Combinatorial Control of Leukocyte Chemotaxis
1997
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Redox Paradox
2005
Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway
2007
The Renal Expression of Transforming Growth Factor-β Isoforms and Their Receptors in Acute and Chronic Experimental Diabetes in Rats*
2000
The NADPH Oxidase Nox4 and Aging in the Heart
2010
Human hepatic stellate cells express class I alcohol dehydrogenase and aldehyde dehydrogenase but not cytochrome P4502E1
1998
Mechanisms of Diabetic Complications
2013 Standout
Transforming growth factor-β1 regulates platelet-derived growth factor receptor β subunit in human liver fat-storing cells
1995
Reduction of Diabetes-Induced Oxidative Stress, Fibrotic Cytokine Expression, and Renal Dysfunction in Protein Kinase Cβ–Null Mice
2006
Imaging the glycome
2008 StandoutNobel
Tubulointerstitial disease in glomerulonephritis. Potential role of osteopontin (uropontin).
1994
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
Early myotome specification regulates PDGFA expression and axial skeleton development
2000
The Molecular Biology of Axon Guidance
1996 StandoutScience
Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes Mellitus
2011
Expression of monocyte chemotactic protein-1 in human invasive ductal breast cancer
1998
Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models
2003
Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.
1994 Standout
Integrin‐mediated stimulation of monocyte chemotactic protein‐1 expression
1997
Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats
2010
Nox2-containing NADPH oxidase and Akt activation play a key role in angiotensin II-induced cardiomyocyte hypertrophy
2006
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
2012 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
Insulin-Like Growth Factors Stimulate Expression of Hepatocyte Growth Factor But Not Transforming Growth Factor β1 in Cultured Hepatic Stellate Cells*
1997
Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis.
1996
Requirement for Rac1-Dependent NADPH Oxidase in the Cardiovascular and Dipsogenic Actions of Angiotensin II in the Brain
2004
Mitogenic effect of platelet-derived growth factor in human glomerular mesangial cells: modulation and/or suppression by inflammatory cytokines
1991
Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction
2016 StandoutNobel
Works of Hanna E. Abboud being referenced
Subcellular localization of Nox4 and regulation in diabetes
2009
NAD(P)H Oxidases Regulate HIF-2α Protein Expression
2007
Reciprocal Induction of Simple Organogenesis by Mouse Kidney Progenitor Cells in Three-Dimensional Co-Culture
2011
Endothelin stimulates PDGF secretion in cultured human mesangial cells
1990
Expression of platelet-derived growth factor in a model of acute liver injury†
1994
Kidney involvement in a nongenetic rat model of type 2 diabetes
2005
Stage IV Chronic Kidney Disease
2010
Platelet-derived Growth Factor Receptor β Regulates Migration and DNA Synthesis in Metanephric Mesenchymal Cells
2000
Platelet-derived growth factor and mesangial cells
1992
Simvastatin inhibits PDGF-induced DNA synthesis in human glomerular mesangial cells
1993
Regulation of human mesangial cell growth in culture by thromboxane A2 and prostacyclin
1990
Chemokines and renal disease
1995
Secretion of Insulin-Like Growth Factor-I and Binding Proteins by Rat Liver Fat-Storing Cells: Regulatory Role of Platelet-Derived Growth Factor*
1990
Growth factors in glomerulonephritis
1993
Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells
2003
Fibronectin induces ureteric bud cells branching and cellular cord and tubule formation
2004
PI 3 kinase-dependent Akt kinase and PKCε independently regulate interferon-γ-induced STAT1α serine phosphorylation to induce monocyte chemotactic protein-1 expression
2005
PDGF stimulates tyrosine phosphorylation of JAK 1 protein tyrosine kinase in human mesangial cells
1996
Insulin regulation of protein translation repressor 4E-BP1, an eIF4E-binding protein, in renal epithelial cells
2001
NAD(P)H Oxidase Mediates TGF-β1–Induced Activation of Kidney Myofibroblasts
2009
Actions of platelet‐derived growth factor isoforms in mesangial cells
1994
Platelet derived growth factor-A chain gene expression in cultured mesangial cells: Regulation by phorbol ester at the level of mRNA abundance, transcription and mRNA stability
1993
AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes
2010
Tyrosine phosphorylation-dependent PI 3 kinase/Akt signal transduction regulates TGFβ-induced fibronectin expression in mesangial cells
2003
Regulation of platelet-derived growth factor secretion and gene expression in human liver fat-storing cells
1994
Nox4 NAD(P)H Oxidase Mediates Hypertrophy and Fibronectin Expression in the Diabetic Kidney
2005
Thrombin Regulates Expression of Monocyte Chemoattractant Protein-1 in Vascular Smooth Muscle Cells
1995
A Complex Element Regulates IFN-γ-Stimulated Monocyte Chemoattractant Protein-1 Gene Transcription
1998
Temporal expression of autocrine growth factors corresponds to morphological features of mesangial proliferation in Habu snake venom-induced glomerulonephritis.
1993
A Nuclear Protein in Mesangial Cells That Binds to the Promoter Region of the Platelet-derived Growth Factor-A Chain Gene
1995
Resident glomerular cells in glomerular injury: mesangial cells.
1991
Thrombin stimulates proliferation of liver fat-storing cells and expression of monocyte chemotactic protein-1: Potential role in liver injury
1995
Expression of Transforming Growth Factor-β and Type IV Collagen in Early Streptozotocin-Induced Diabetes
1997
A complex element regulates IFN-gamma-stimulated monocyte chemoattractant protein-1 gene transcription.
1998
Angiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cells
2004
Nox4-derived reactive oxygen species mediate cardiomyocyte injury in early type 1 diabetes
2011
Regulation of protein synthesis by IGF-I in proximal tubular epithelial cells
2002
ZΟ-1 Expression and Phosphorylation in Diabetic Nephropathy
2006
Mechanism of Oxidative DNA Damage in Diabetes
2008
Insulin regulation of protein translation repressor 4E-BP1, an eIF4E-binding protein, in renal epithelial cells
2001
Expression of bone morphogenetic protein-7 mRNA in normal and ischemic adult rat kidney
1999
Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony-stimulating factors, and interleukin-6 in human mesangial cells.
1991
Angiotensin II activates Akt/protein kinase B by an arachidonic acid/redox‐dependent pathway and independent of phosphoinositide 3‐kinase
2001
A Single Nucleotide Polymorphism in MGEA5 Encoding O-GlcNAc–selective N-Acetyl-β-d Glucosaminidase Is Associated With Type 2 Diabetes in Mexican Americans
2005
PI-3-kinase and MAPK regulate mesangial cell proliferation and migration in response to PDGF
1997