Standout Papers
Citation Impact
Citing Papers
Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals
2012 Science
Akt1 and Akt2 promote peripheral B-cell maturation and survival
2009
Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex
2005 StandoutScience
An Activating Mutation of AKT2 and Human Hypoglycemia
2011 Science
Akt1 Is Required for Physiological Cardiac Growth
2006
TRB3: A tribbles Homolog That Inhibits Akt/PKB Activation by Insulin in Liver
2003 Science
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
2004 StandoutScience
Akt1 Ablation Inhibits, whereas Akt2 Ablation Accelerates, the Development of Mammary Adenocarcinomas in Mouse Mammary Tumor Virus (MMTV)-ErbB2/Neu and MMTV-Polyoma Middle T Transgenic Mice
2007
JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16
2005
Akt/Protein Kinase B Signaling Inhibitor-2, a Selective Small Molecule Inhibitor of Akt Signaling with Antitumor Activity in Cancer Cells Overexpressing Akt
2004
PKB/AKT: functional insights from genetic models
2001
PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling
2015
SRC-2 Is an Essential Coactivator for Orchestrating Metabolism and Circadian Rhythm
2014
Hallmarks of Cancer: The Next Generation
2011 Standout
Ceramides as modulators of cellular and whole-body metabolism
2011
Opportunities and challenges in the development of kinase inhibitor therapy for cancer
2003
The circadian epigenome: how metabolism talks to chromatin remodeling
2013
siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle
2006
Genome-Wide RNA Polymerase II Profiles and RNA Accumulation Reveal Kinetics of Transcription and Associated Epigenetic Changes During Diurnal Cycles
2012
Akt and Rac1 signaling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance
2013
Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis
2009
Knockout models are useful tools to dissect the pathophysiology and genetics of insulin resistance
2002
Transcriptomic profiling of microglia and astrocytes throughout aging
2020
Rab10, a Target of the AS160 Rab GAP, Is Required for Insulin-Stimulated Translocation of GLUT4 to the Adipocyte Plasma Membrane
2007
Transcriptional architecture of the mammalian circadian clock
2016 Standout
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Loss of Akt1 Leads to Severe Atherosclerosis and Occlusive Coronary Artery Disease
2007
Inflammation and metabolic disorders
2006 StandoutNature
Regulation of glucose transport by insulin: traffic control of GLUT4
2012
Molecular architecture of the mammalian circadian clock
2013
Mice with AS160/TBC1D4-Thr649Ala Knockin Mutation Are Glucose Intolerant with Reduced Insulin Sensitivity and Altered GLUT4 Trafficking
2011
A proteolytic pathway that controls glucose uptake in fat and muscle
2013
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
2006 Standout
PTEN, but Not SHIP2, Suppresses Insulin Signaling through the Phosphatidylinositol 3-Kinase/Akt Pathway in 3T3-L1 Adipocytes
2005
Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBβ
2003
Alterations of insulin signaling in type 2 diabetes: A review of the current evidence from humans
2008
Two Membrane-Associated Tyrosine Phosphatase Homologs Potentiate C. elegans AKT-1/PKB Signaling
2006 StandoutNobel
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene
2001
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
2001 StandoutNature
Circadian Dbp Transcription Relies on Highly Dynamic BMAL1-CLOCK Interaction with E Boxes and Requires the Proteasome
2012
A Role for Ceramide, but Not Diacylglycerol, in the Antagonism of Insulin Signal Transduction by Saturated Fatty Acids
2003
Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B–null mice
2006
The Akt–SREBP nexus: cell signaling meets lipid metabolism
2010
Wound repair and regeneration
2008 StandoutNature
Autophagy regulates lipid metabolism
2009 StandoutNature
Protein kinase cascades in the regulation of cardiac hypertrophy
2005
Phosphoproteomics Screen Reveals Akt Isoform-Specific Signals Linking RNA Processing to Lung Cancer
2014
The Mediator complex: a central integrator of transcription
2015
PHLPP and a Second Isoform, PHLPP2, Differentially Attenuate the Amplitude of Akt Signaling by Regulating Distinct Akt Isoforms
2007
The Identification of ATP-citrate Lyase as a Protein Kinase B (Akt) Substrate in Primary Adipocytes
2002
Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1
2012
PDK1, the master regulator of AGC kinase signal transduction
2004
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2
2012
Gene Model 129 (Gm129) Encodes a Novel Transcriptional Repressor That Modulates Circadian Gene Expression
2014 StandoutNobel
Loss of class IA PI3K signaling in muscle leads to impaired muscle growth, insulin response, and hyperlipidemia
2006
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Inactivation of Hepatic Foxo1 by Insulin Signaling Is Required for Adaptive Nutrient Homeostasis and Endocrine Growth Regulation
2008
The role of protein translocation in the regulation of glycogen metabolism
2007
Hepatocyte CYP2E1 Overexpression and Steatohepatitis Lead to Impaired Hepatic Insulin Signaling
2005
Competing E3 Ubiquitin Ligases Govern Circadian Periodicity by Degradation of CRY in Nucleus and Cytoplasm
2013
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2
2003
Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes
2003
PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3
2004
From JNK to Pay Dirt: Jun Kinases, their Biochemistry, Physiology and Clinical Importance
2005
IKK-β links inflammation to obesity-induced insulin resistance
2005
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2
2007 Nature
Regulation of Insulin Action by Ceramide
2004
PARP1- and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription
2015
Targeting phosphoinositide 3-kinase—Moving towards therapy
2007
Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
2005 Standout
Targeting the phosphoinositide 3-kinase pathway in cancer
2009 Standout
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
2005
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
Rho GTPases in insulin-stimulated glucose uptake
2014
Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action
2005
The effect Akt2 deletion on tumor development in Pten+/− mice
2011
A Partial Loss-of-Function Variant in AKT2 Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study
2017
Akt1/protein kinase B is critical for ischemic and VEGF-mediated angiogenesis
2005
Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation
2006 Nature
A central role for JNK in obesity and insulin resistance
2002 StandoutNature
Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
2006
Circadian control of the immune system
2013 Standout
Perturbations of the AKT signaling pathway in human cancer
2005
Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes
2014
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction
2009
Insulin Receptor Signaling in Normal and Insulin-Resistant States
2014
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Insulin action and resistance in obesity and type 2 diabetes
2017
Identification of a Proline-rich Akt Substrate as a 14-3-3 Binding Partner
2003
Signalling by insulin and IGF receptors: supporting acts and new players
2011
Advances in protein kinase B signalling: AKTion on multiple fronts
2004
Use of RNA Interference-mediated Gene Silencing and Adenoviral Overexpression to Elucidate the Roles of AKT/Protein Kinase B Isoforms in Insulin Actions
2003
C2 Domain-Containing Phosphoprotein CDP138 Regulates GLUT4 Insertion into the Plasma Membrane
2011
The GLUT4 Glucose Transporter
2007
Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis
2011
Circadian topology of metabolism
2012 Nature
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress
2004
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin
2006
Signalling and autophagy regulation in health, aging and disease
2006
Histone monoubiquitination by Clock–Bmal1 complex marks Per1 and Per2 genes for circadian feedback
2015
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure
2005
Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein
2005
A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
2005
SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth
2008
The role of mouse Akt2 in insulin-dependent suppression of adipocyte lipolysis in vivo
2015
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Circadian Clock Proteins and Immunity
2014
Akt2 Is Required for Hepatic Lipid Accumulation in Models of Insulin Resistance
2009
The twentieth century struggle to decipher insulin signalling
2006
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
The role of protein kinase B/Akt in insulin-induced inactivation of phosphorylase in rat hepatocytes
2005
Akt3 Deficiency in Macrophages Promotes Foam Cell Formation and Atherosclerosis in Mice
2012
Timing to Perfection: The Biology of Central and Peripheral Circadian Clocks
2012
Convergent evidence for impaired AKT1-GSK3β signaling in schizophrenia
2004
Transcriptional regulation of hepatic lipogenesis
2015
Clocks, Metabolism, and the Epigenome
2012
Differential Contribution of Insulin Receptor Substrates 1 Versus 2 to Insulin Signaling and Glucose Uptake in L6 Myotubes
2005
Transgenic mice with dominant negative PKC‐theta in skeletal muscle: A new model of insulin resistance and obesity
2003
PTEN function in mammalian cell size regulation
2002
AKT/PKB Signaling: Navigating the Network
2017 Standout
Genetics of Type 2 diabetes
2005
Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ
2006
Architectural and Functional Commonalities between Enhancers and Promoters
2015
Regulation of pancreatic β-cell growth and survival by the serine/threonine protein kinase Akt1/PKBα
2001
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
2005 StandoutNature
Regulation of cardiac hypertrophy by intracellular signalling pathways
2006 Standout
Rapid Activation of Akt2 Is Sufficient to Stimulate GLUT4 Translocation in 3T3-L1 Adipocytes
2008
Loss of ARNT/HIF1β Mediates Altered Gene Expression and Pancreatic-Islet Dysfunction in Human Type 2 Diabetes
2005
Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock
2014 StandoutNobel
Coactivator-Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude via REV-ERB Loading
2015
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
2009 Standout
Protein Kinase C θ Inhibits Insulin Signaling by Phosphorylating IRS1 at Ser1101
2004
The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease
2004
Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1
2006
Circadian Oscillations of Protein-Coding and Regulatory RNAs in a Highly Dynamic Mammalian Liver Epigenome
2012
Somatic Activation of AKT3 Causes Hemispheric Developmental Brain Malformations
2012
Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance
2004
Atrophy of S6K1−/− skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control
2005
Circadian Enhancers Coordinate Multiple Phases of Rhythmic Gene Transcription In Vivo
2014
BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis
2003 Nature
CLOCK:BMAL1 is a pioneer-like transcription factor
2014 StandoutNobel
Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice
2014
Insulin signalling mechanisms for triacylglycerol storage
2013
The development of phosphatidylinositol ether lipid analogues as inhibitors of the serine/threonine kinase, Akt
2004
Cycles in spatial and temporal chromosomal organization driven by the circadian clock
2013
Insulin signaling to hepatic lipid metabolism in health and disease
2011
Molecular regulation of effector and memory T cell differentiation
2014
A Method to Identify Serine Kinase Substrates
2002
Growth Factor-Dependent Trafficking of Cerebellar NMDA Receptors via Protein Kinase B/Akt Phosphorylation of NR2C
2009
Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action
2016
Ceramide dissociates 3′-phosphoinositide production from pleckstrin homology domain translocation
2001
Muscle-Specific Pten Deletion Protects against Insulin Resistance and Diabetes
2005 StandoutNobel
Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signaling and ceramide synthesis in vivo
2013
Metabolic cross-talk allows labeling of O-linked β- N -acetylglucosamine-modified proteins via the N -acetylgalactosamine salvage pathway
2011 StandoutNobel
The Pathophysiology of Mitochondrial Cell Death
2004 StandoutScience
CLOCK-Controlled Polyphonic Regulation of Circadian Rhythms through Canonical and Noncanonical E-Boxes
2014
Insulin Signaling Diverges into Akt-dependent and -independent Signals to Regulate the Recruitment/Docking and the Fusion of GLUT4 Vesicles to the Plasma Membrane
2006
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Analysis of insulin signalling by RNAi-based gene silencing
2004
Mechanism and Management of AKT Inhibitor-Induced Hyperglycemia
2008
Protein Phosphatase 2A Negatively Regulates Insulin's Metabolic Signaling Pathway by Inhibiting Akt (Protein Kinase B) Activity in 3T3-L1 Adipocytes
2004
Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing
2003
Metabolic and Nontranscriptional Circadian Clocks: Eukaryotes
2014
A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2
2004 Science
Regulation of Phosphoinositide Metabolism, Akt Phosphorylation, and Glucose Transport by PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome 10) in 3T3-L1 Adipocytes
2001
Essential, Nonredundant Role for the Phosphoinositide 3-Kinase p110δ in Signaling by the B-Cell Receptor Complex
2002
A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action
2010
Phosphoinositide 3-Kinase Catalytic Subunit Deletion and Regulatory Subunit Deletion Have Opposite Effects on Insulin Sensitivity in Mice
2005
An ATP-Site On-Off Switch That Restricts Phosphatase Accessibility of Akt
2012
Emerging Models for the Molecular Basis of Mammalian Circadian Timing
2014
Physiological roles of PKB/Akt isoforms in development and disease
2007
Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles
2005
Insulin Hypersensitivity and Resistance to Streptozotocin-Induced Diabetes in Mice Lacking PTEN in Adipose Tissue
2005
Insulin Regulates Adipocyte Lipolysis via an Akt-Independent Signaling Pathway
2010
PKB/Akt
2001
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
MicroRNAs shape circadian hepatic gene expression on a transcriptome-wide scale
2014
Differential Effects of Protein Kinase B/Akt Isoforms on Glucose Homeostasis and Islet Mass
2009
Trk Receptors: Roles in Neuronal Signal Transduction
2003 Standout
Uses for JNK: the Many and Varied Substrates of the c-Jun N-Terminal Kinases
2006
Suppressor of Cytokine Signaling 1 (SOCS-1) and SOCS-3 Cause Insulin Resistance through Inhibition of Tyrosine Phosphorylation of Insulin Receptor Substrate Proteins by Discrete Mechanisms
2004
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3
2004
The phosphatidylinositol-3-kinase inhibitor PX-866 overcomes resistance to the epidermal growth factor receptor inhibitor gefitinib in A-549 human non–small cell lung cancer xenografts
2005
Increased insulin sensitivity in mice lacking p85β subunit of phosphoinositide 3-kinase
2001
Mammalian Period represses and de-represses transcription by displacing CLOCK–BMAL1 from promoters in a Cryptochrome-dependent manner
2016 Nobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Essential role of protein kinase Bγ (PKBγ/Akt3) in postnatal brain development but not in glucose homeostasis
2005
Sphingolipids, Insulin Resistance, and Metabolic Disease: New Insights from in Vivo Manipulation of Sphingolipid Metabolism
2008
A Noncanonical, GSK3-Independent Pathway Controls Postprandial Hepatic Glycogen Deposition
2013
Fat Cell–Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism
2010
Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial–mesenchymal transition
2005
Critical nodes in signalling pathways: insights into insulin action
2006 Standout
Cellular Function of Phosphoinositide 3-Kinases: Implications for Development, Immunity, Homeostasis, and Cancer
2001
Insulin Receptor Substrates Irs1 and Irs2 Coordinate Skeletal Muscle Growth and Metabolism via the Akt and AMPK Pathways
2010
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity
2004
A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery
2013
Akt isoforms differentially regulate neutrophil functions
2010
Hepatic Akt Activation Induces Marked Hypoglycemia, Hepatomegaly, and Hypertriglyceridemia With Sterol Regulatory Element Binding Protein Involvement
2003
Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival
2003
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
The Pim kinases control rapamycin-resistant T cell survival and activation
2005
Regulation of Glucose Transporter Translocation in Health and Diabetes
2012
NOX4 Pathway as a Source of Selective Insulin Resistance and Responsiveness
2012
Akt/Protein Kinase B Promotes Organ Growth in Transgenic Mice
2002
Nascent-Seq analysis of Drosophila cycling gene expression
2013 StandoutNobel
Metabolism and the Circadian Clock Converge
2013
Life with a Single Isoform of Akt: Mice Lacking Akt2 and Akt3 Are Viable but Display Impaired Glucose Homeostasis and Growth Deficiencies
2006
Ceramide Disables 3-Phosphoinositide Binding to the Pleckstrin Homology Domain of Protein Kinase B (PKB)/Akt by a PKCζ-Dependent Mechanism
2003
Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals
2003
Myosin 5a Is an Insulin-Stimulated Akt2 (Protein Kinase Bβ) Substrate Modulating GLUT4 Vesicle Translocation
2007
Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors
2005
Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization
2012
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Turning Signals On and Off: GLUT4 Traffic in the Insulin-Signaling Highway
2005
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Antiapoptotic Role of PPARβ in Keratinocytes via Transcriptional Control of the Akt1 Signaling Pathway
2002
PP2A inhibition results in hepatic insulin resistance despite Akt2 activation
2013
Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock
2015 Science
The Phosphoinositide 3-Kinase Pathway
2002 StandoutScience
Signal transduction meets vesicle traffic: the software and hardware of GLUT4 translocation
2014
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates
2014
Specificity in Circadian Clock Feedback from Targeted Reconstitution of the NuRD Corepressor
2014
Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation
2001
Absence of Akt1 Reduces Vascular Smooth Muscle Cell Migration and Survival and Induces Features of Plaque Vulnerability and Cardiac Dysfunction During Atherosclerosis
2009
Akt1 and Akt2 are required for αβ thymocyte survival and differentiation
2007
Increased p85/55/50 Expression and Decreased Phosphotidylinositol 3-Kinase Activity in Insulin-Resistant Human Skeletal Muscle
2005
Works of Han Cho being referenced
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
2001 StandoutScience
Isoform-specific Regulation of Insulin-dependent Glucose Uptake by Akt/Protein Kinase B
2003
Signaling Pathways Mediating Insulin‐Stimulated Glucose Transport
1999
Akt1 Regulates a JNK Scaffold during Excitotoxic Apoptosis
2002
Role of Akt/protein kinase B in metabolism
2002
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β
2012 Nature
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
2013 Nature
Differentiation-dependent Suppression of Platelet-derived Growth Factor Signaling in Cultured Adipocytes
1999
Akt1/PKBα Is Required for Normal Growth but Dispensable for Maintenance of Glucose Homeostasis in Mice
2001
Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation
2006
Nuclear receptors rock around the clock
2014
Role for Akt3/Protein Kinase Bγ in Attainment of Normal Brain Size
2005