Standout Papers
Citation Impact
Citing Papers
Anthelmintic Avermectins Kill Mycobacterium tuberculosis, Including Multidrug-Resistant Clinical Strains
2012
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells
2019 StandoutNobel
Genome sequence of an industrial microorganism Streptomyces avermitilis : Deducing the ability of producing secondary metabolites
2001 StandoutNobel
Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol
2008 StandoutNobel
Satoshi Ōmura: in pursuit of nature's bounty
2005
Mangromicins, six new anti-oxidative agents isolated from a culture broth of the actinomycete, Lechevalieria aerocolonigenes K10-0216
2014 StandoutNobel
The onchocerciasis chronicle: from the beginning to the end?
2012 StandoutNobel
Avermectin binding in Caenorhabditis elegans
1989
Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector
1992
The life and times of ivermectin — a success story
2004 StandoutNobel
Bisphosphonates: A New Class of Drugs in Diseases of Bone and Calcium Metabolism
1989
Complex organization of the Streptomyces avermitilis genes encoding the avermectin polyketide synthase
1992
Directed biosynthesis of avermectins
1989
Characterization of a regulatory gene, aveR, for the biosynthesis of avermectin in Streptomyces avermitilis
2009
Cytochrome P450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2)
2003 StandoutNobel
Asymmetric spiroacetalization catalysed by confined Brønsted acids
2012 StandoutNatureNobel
Semi-synthetic DNA shuffling of aveC leads to improved industrial scale production of doramectin by Streptomyces avermitilis
2005
Ivermectin: A Positive Allosteric Effector of the α7 Neuronal Nicotinic Acetylcholine Receptor
1998
Methicillin-Resistant Staphylococcus aureus
1989 Standout
Ivermectin Inhibits Growth of Chlamydia trachomatis in Epithelial Cells
2012
The worm has turned – microbial virulence modeled in Caenorhabditis elegans
2005
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis
2003 StandoutNobel
The Catalytic Asymmetric Abramov Reaction
2014 StandoutNobel
Advances in drug discovery and biochemical studies
2007 StandoutNobel
Synthesis and biological activities of novel 4″-alkylidene avermectin derivatives
2003 StandoutNobel
Production of 6,8a-Seco-6,8a-deoxy Derivatives of Avermectins by a Mutant Strain of Streptomyces avermitilis.
1995 StandoutNobel
Emergence of vancomycin tolerance in Streptococcus pneumoniae
1999 StandoutNatureNobel
Cloning of the gene encoding avermectin B 5-O-methyltransferase in avermectin-producing Streptomyces avermitilis
1998 StandoutNobel
Studies on the biosynthesis of avermectins
1989
Ivermectin: panacea for resource-poor communities?
2014 StandoutNobel
Organophosphonates revealed: new insights into the microbial metabolism of ancient molecules
2013
Catalytic Asymmetric Synthesis of Phosphine Boronates
2015 StandoutNobel
Inhibitory glutamate receptor channels
1996
Efficacy of Pamidronate in Reducing Skeletal Complications in Patients with Breast Cancer and Lytic Bone Metastases
1996 Standout
Pharmaceutically active secondary metabolites of microorganisms
1999
Ivermectin: 25 years and still going strong
2007 StandoutNobel
Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation
2011
Antibacterial drug discovery in the resistance era
2016 StandoutNature
Novel Enzymatic Mechanisms in Carbohydrate Metabolism
2000
Characterization of the ω-hydroxylase of Pseudomonas oleovorans as a nonheme iron protein
1977
Further studies on the biosynthesis of the avermectins
1989
Involvement of glucose catabolism in avermectin production by Streptomyces avermitilis
1988 StandoutNobel
Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis
2011 StandoutNobel
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Avermectins: novel insecticides, acaricides and nematicides from a soil microorganism
1981
Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells.
1988 Standout
Efficacy of Avermectins against Dirofilaria immitis in dogs
1978
Partial syntheses of avermectin Bla and ivermectin from avermectin B2a
1982
Ivermectin, 'Wonder drug' from Japan: the human use perspective
2011 StandoutNobel
(1,2‐Epoxy‐3‐oxoalkyl)phosphonsäureester als Synthone für heterocyclische Carbonylverbindungen: Synthese von acylsubstituierten Thiazolen, Indolizinen, Imidazo[1,2‐a]‐pyridinen und Imidazo[1,2‐a]pyrimidinen
1985
Structural and Functional Aspects of Metal Sites in Biology
1996 Standout
Methylation of demethylavermectins
1987
Avermectins, New Family of Potent Anthelmintic Agents: Isolation and Chromatographic Properties
1979
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
2000 StandoutNatureNobel
The synthesis of enantiomerically pure, symmetrically substituted cyclopropane phosphonic acids — A constrained analog of the GABA antagonist phaclophen
1997
Energization of Active Transport by Escherichia coli
1972 StandoutNobel
Silicon directed asymmetric synthesis of (1R, 2S)-(−)-(1,2-Epoxypropyl)phosphonic acid (fosfomycin) from (S)-lactaldehyde
1995
Demethylavermectins. Biosynthesis, isolation and characterization.
1985
Cloning and sequencing of a cluster of genes encoding branched-chain alpha-keto acid dehydrogenase from Streptomyces avermitilis and the production of a functional E1 [alpha beta] component in Escherichia coli
1995
Phosphine Organocatalysis
2018 Standout
Avermectins, New Family of Potent Anthelmintic Agents: Efficacy of the B 1a Component
1979
Avermectin B2 O-methyltransferase activity in "Streptomyces avermitilis" mutants that produce increased amounts of the avermectins
1986
An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria
2000 StandoutNobel
Pentalenolactone Biosynthesis. Molecular Cloning and Assignment of Biochemical Function to PtlH, A Non-Heme Iron Dioxygenase of Streptomyces avermitilis
2006 StandoutNobel
Protoplast fusion inStreptomyces avermitilis
1988
A Streptomyces avermitilis gene encoding a 4-hydroxyphenylpyruvic acid dioxygenase-like protein that directs the production of homogentisic acid and an ochronotic pigment in Escherichia coli
1994
Microbial metabolites: 45 years of wandering, wondering and discovering
2011 StandoutNobel
Transposon mutagenesis by Tn4560 and applications with avermectin-producing Streptomyces avermitilis
1993 StandoutNobel
The autoregulator receptor homologue AvaR3 plays a regulatory role in antibiotic production, mycelial aggregation and colony development of Streptomyces avermitilis
2011
The complete genomic sequence of Nocardia farcinica IFM 10152
2004 Standout
Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism
2010 StandoutNobel
Copper-Catalyzed Synthesis of Mixed Alkyl Aryl Phosphonates
2014 StandoutNobel
Stereoselective Cyclopropanation Reactions
2003 Standout
"Streptomyces avermitilis" mutants defective in methylation of avermectins
1987
Biosynthesis of the avermectins by Streptomyces avermitilis. Incorporation of labeled precursors.
1986
Deletion analysis of the avermectin biosynthetic genes of Streptomyces avermitilis by gene cluster displacement
1993
Oxidative phosphorylation in fractionated bacterial systems
1963
Me 3 P-catalyzed addition of hydrogen phosphoryl compounds P(O)H to electron-deficient alkenes: 1 to 1 vs 1 to 2 adducts
2017
Septicémies et infections graves à germes multirésistants. Résultats du traitement par la fosfomycine
1981
Avermectin Biosynthesis
1997 StandoutNobel
Small Molecule Natural Products in the Discovery of Therapeutic Agents: The Synthesis Connection
2006
22, 23–Dihydroavermectin B 1 , A New Broad-Spectrum Antiparasitic Agent
1980
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Genetic studies of avermectin biosynthesis in Streptomyces avermitilis
1987 StandoutNobel
Pentalenolactone Biosynthesis. Molecular Cloning and Assignment of Biochemical Function to PtlI, a Cytochrome P450 of Streptomyces avermitilis
2006 StandoutNobel
Dioxirane Oxidation of 2‐Aryl‐1‐vinyl‐1, 1‐diphosphane Dioxide: A Convenient Approach for the Synthesis of Novel 1,2‐Epoxy‐2‐aryl Ethylgembisphosphonates
2013
A second branched-chain alpha-keto acid dehydrogenase gene cluster (bkdFGH) from Streptomyces avermitilis: its relationship to avermectin biosynthesis and the construction of a bkdF mutant suitable for the production of novel antiparasitic avermectins
1995
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
EngineeredStreptomyces avermitilisHost for Heterologous Expression of Biosynthetic Gene Cluster for Secondary Metabolites
2013 StandoutNobel
Thioamides as Useful Synthons in the Synthesis of Heterocycles
2002 Standout
Multiple Antibiotic Resistance in a Bacterium with Suppressed Autolytic System
1970 Nature
Enzymatic aminoacylation of tRNA with unnatural amino acids
2006 StandoutNobel
Immunoaffinity purification of avermectin-binding proteins from the free-living nematode Caenorhabditis elegans and the fruitfly Drosophila melanogaster
1994
Milbemycins, a new family of macrolide antibiotics. Structure determination of milbemycins D,E,F,G,H,J and K.
1983
Streptomyces avermectinius sp. nov., an avermectin-producing strain.
2002 StandoutNobel
Efficacy of the avermectins against filarial parasites: A short review
1981
Postsynaptic inhibition of invertebrate neuromuscular transmission by avermectin B1a
1983
Synthesis of 4″-alkoxy avermectin derivatives using rhodium carbenoid-mediated O–H insertion reaction
2004 StandoutNobel
Ivermectin: A Potent New Antiparasitic Agent
1983 Science
An Introduction to the Avermectins
1981
Actions of dihydroavermectin B1α on insect muscle
1985
Jietacins with potent nematocidal activity; efficient isolation of novel analogs and divergent total synthesis of jietacin A, B, C, and D
2015 StandoutNobel
Purification and identification of dTDP-oleandrose, the precursor of the oleandrose units of the avermectins.
1990
Terpene synthases are widely distributed in bacteria
2014 StandoutNobel
Environmental consequences of treating cattle with the antiparasitic drug ivermectin
1987 Nature
Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters
2013 StandoutNobel
Challenges of Antibacterial Discovery
2011
Hydroxymethylfurfural, A Versatile Platform Chemical Made from Renewable Resources
2013 Standout
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis
1999
Discovery, production and purification of the Na+,K+ activated ATPase inhibitor, L-681,110 from the fermentation broth of Streptomyces sp. MA-5038.
1984
The Natural Biotic Environment ofCaenorhabditis elegans
2017
Works of H. Wallick being referenced
Coenzyme Q. XVII. Isolation of coenzyme Q10 from bacterial fermentation
1960
Avermectins, New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation
1979 StandoutNobel
Phosphonomycin, a New Antibiotic Produced by Strains of Streptomyces
1969 Science
Fosfomycin: Laboratory Studies
1977