Citation Impact
Citing Papers
[18F](2 S ,4 R )4-Fluoroglutamine PET Detects Glutamine Pool Size Changes in Triple-Negative Breast Cancer in Response to Glutaminase Inhibition
2017
Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors
2012 Standout
rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data
2014 Standout
Non-Identity-Mediated CRISPR-Bacteriophage Interaction Mediated via the Csy and Cas3 Proteins
2011
DNA-Encoded Chemical Libraries: A Selection System Based on Endowing Organic Compounds with Amplifiable Information
2018
Stereospecific PARP Trapping by BMN 673 and Comparison with Olaparib and Rucaparib
2013
A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation–Driven Colorectal Tumor Growth
2013
Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer
2014
Sulfur [ 18 F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis
2021 StandoutNobel
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
Palladium-catalyzed N-arylation of 2-aminobenzothiazole-4-carboxylates/carboxamides: facile synthesis of PARP14 inhibitors
2014
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Target engagement imaging of PARP inhibitors in small-cell lung cancer
2018
Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells
2020 StandoutNobel
GLiMMPS: robust statistical model for regulatory variation of alternative splicing using RNA-seq data
2013
The Spring α-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action
2016 StandoutNobel
PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage
2013
Mutant actins that stabilise F‐actin use distinct mechanisms to activate the SRF coactivator MAL
2004
Structural Insights into RNA Recognition by RIG-I
2011
A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export
2011 Nature
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
Regulation of microRNA biogenesis
2014 Standout
Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3
2015 StandoutNobel
The Spliceosome: Design Principles of a Dynamic RNP Machine
2009 Standout
Inheritance of Silent rDNA Chromatin Is Mediated by PARP1 via Noncoding RNA
2012
Evolutionarily Conserved Roles of the Dicer Helicase Domain in Regulating RNA Interference Processing
2014 StandoutNobel
Ubiquitin Ligase RNF146 Regulates Tankyrase and Axin to Promote Wnt Signaling
2011
Identification of the HcgB Enzyme in [Fe]‐Hydrogenase‐Cofactor Biosynthesis
2013
Eukaryotic chaperonin CCT stabilizes actin and tubulin folding intermediates in open quasi-native conformations
2000
Rare and unusual glycosylation of peptides and proteins
2012
The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets
2010
Structural Basis and Sequence Rules for Substrate Recognition by Tankyrase Explain the Basis for Cherubism Disease
2011
From unwinding to clamping — the DEAD box RNA helicase family
2011
Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1
2010
Shedding light on the cell biology of extracellular vesicles
2018 Standout
The diverse roles and clinical relevance of PARPs in DNA damage repair: Current state of the art
2012
Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo
2013
High-resolution structure prediction and the crystallographic phase problem
2007 StandoutNatureNobel
Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes
2011 StandoutNobel
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm
2011
PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain
2015
In vivo imaging of specific drug–target binding at subcellular resolution
2014
Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate
2010
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
Synthetic lethality: the road to novel therapies for breast cancer
2016
Rho GTPases and their roles in cancer metabolism
2012
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Tropomyosin and Gelsolin Cooperate in Controlling the Microfilament System
2002
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Crystal Structure of Monomeric Actin in the ATP State
2003
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
2004 StandoutNature
Structural Insights into a Unique Dimeric DEAD-Box Helicase CshA that Promotes RNA Decay
2017
A Key Role for Poly(ADP-Ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development
2011
Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery
2020 StandoutNobel
PARP inhibition: PARP1 and beyond
2010
Long Noncoding RNAs: Cellular Address Codes in Development and Disease
2013 Standout
Proteome-wide Profiling of Clinical PARP Inhibitors Reveals Compound-Specific Secondary Targets
2016
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Functional diversity of organic molecule enzyme cofactors
2013
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
Cellular Motility Driven by Assembly and Disassembly of Actin Filaments
2003 Standout
ATP-Dependent Effector-like Functions of RIG-I-like Receptors
2015 StandoutNobel
The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings
2011
In vivo 3′-to-5′ exoribonuclease targetomes of Streptococcus pyogenes
2018 StandoutNobel
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Mutant Actins Demonstrate a Role for Unpolymerized Actin in Control of Transcription by Serum Response Factor
2002
New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs
2012
Roles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAs
2012
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
Electrostatic origin of the mechanochemical rotary mechanism and the catalytic dwell of F1-ATPase
2011 StandoutNobel
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
Poly(ADP-Ribose)Polymerase-1 (PARP1) Controls Adipogenic Gene Expression and Adipocyte Function
2011
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins
2019 StandoutNobel
Hydrogenases
2014 Standout
TLR9 and MyD88 Are Crucial for the Development of Protective Immunity to Malaria
2012
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
2018
Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein
2002 StandoutScience
On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
2012 Standout
PHD3-mediated prolyl hydroxylation of nonmuscle actin impairs polymerization and cell motility
2014 StandoutNobel
Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron
2012 StandoutNobel
Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs
2019 StandoutNobel
Macromolecular Modeling with Rosetta
2008 StandoutNobel
Biosynthesis of the Iron-Guanylylpyridinol Cofactor of [Fe]-Hydrogenase in Methanogenic Archaea as Elucidated by Stable-Isotope Labeling
2012
Metabolic reprogramming and cancer progression
2020 StandoutScience
DEAD-Box Helicases: Sensors, Regulators, and Effectors for Antiviral Defense
2020
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Aryl-fluorosulfate-based Lysine Covalent Pan-Inhibitors of Apoptosis Protein (IAP) Antagonists with Cellular Efficacy
2019
Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells
2015
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
What is a “DNA-Compatible” Reaction?
2016
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
DEAD-box helicases: the Yin and Yang roles in viral infections
2018
Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
2011
Engineering the Substrate Specificity of ADP-Ribosyltransferases for Identifying Direct Protein Targets
2014
Solution Properties of TMR-Actin: When Biochemical and Crystal Data Agree
2003
Energy Transfer from Adenosine Triphosphate
2006
A Randomized Phase II Study of Veliparib with Temozolomide Or Carboplatin/Paclitaxel Versus Placebo with Carboplatin/Paclitaxel in Brca1 / 2 Metastatic Breast Cancer: Design and Rationale
2016
RADIOLYTIC PROTEIN FOOTPRINTING WITH MASS SPECTROMETRY TO PROBE THE STRUCTURE OF MACROMOLECULAR COMPLEXES
2006
Diverse Effects of Mutations in Exon II of the von Hippel-Lindau (VHL) Tumor Suppressor Gene on the Interaction of pVHL with the Cytosolic Chaperonin and pVHL-Dependent Ubiquitin Ligase Activity
2002 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Modelling dynamics in protein crystal structures by ensemble refinement
2012
Works of H. Schüler being referenced
Crystal Structure of Human Inosine Triphosphatase
2006
Crystal Structures Explain Functional Differences in the Two Actin Depolymerization Factors of the Malaria Parasite
2011
Comparative Structural Analysis of Human DEAD-Box RNA Helicases
2010
PARP-3 Is a Mono-ADP-ribosylase That Activates PARP-1 in the Absence of DNA
2010
Mutational analysis of Ser14 and Asp157 in the nucleotide‐binding site of β‐actin
1999
The DEXD/H-box RNA Helicase DDX19 Is Regulated by an α-Helical Switch
2009
Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium falciparum
2008
Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling
2013
ATPase activity and conformational changes in the regulation of actin
2001
Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains
2013
Crystal Structure of Human RNA Helicase A (DHX9): Structural Basis for Unselective Nucleotide Base Binding in a DEAD-Box Variant Protein
2010
Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymes
2011
Toward a unified nomenclature for mammalian ADP-ribosyltransferases
2010
The role of MeH73 in actin polymerization and ATP hydrolysis 1 1Edited by R. Huber
2002
Identification of Structure–Activity Relationships from Screening a Structurally Compact DNA‐Encoded Chemical Library
2015
Thermal unfolding of G‐actin monitored with the DNase I‐inhibition assay
2000
Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
2012
Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors
2016
Structural Basis for the Interaction between Tankyrase-2 and a Potent Wnt-Signaling Inhibitor
2010
A DNA‐Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition
2018
Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism
2012
Structural Basis for Inhibitor Specificity in Human Poly(ADP-ribose) Polymerase-3
2009
Sirtuins are Unaffected by PARP Inhibitors Containing Planar Nicotinamide Bioisosteres
2015
Tankyrase 1 Inhibitors with Drug-like Properties Identified by Screening a DNA-Encoded Chemical Library
2015
Discovery of Ligands for ADP-Ribosyltransferases via Docking-Based Virtual Screening
2012
Crystal Structure of the Catalytic Domain of Human PARP2 in Complex with PARP Inhibitor ABT-888
2010
PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ARTD3/PARP3
2013