Citation Impact
Citing Papers
Long-Lived C. elegans daf-2 Mutants Are Resistant to Bacterial Pathogens
2003 StandoutScienceNobel
Ageing populations: the challenges ahead
2009 Standout
Association of apolipoprotein E polymorphism with outcome after head injury
1997 Standout
Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease
1996
A unified mixed-model method for association mapping that accounts for multiple levels of relatedness
2005 Standout
Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants
2007 StandoutNobel
A New Variant of Charcot-Marie-Tooth Disease Type 2 Is Probably the Result of a Mutation in the Neurofilament-Light Gene
2000
Increased poly(ADP-ribose) polymerase activity in lymphoblastoid cell lines from centenarians
1998
Incidence of amyotrophic lateral sclerosis in Europe
2009
DNA multiallelic systems reveal gene/longevity associations not detected by diallelic systems. The APOB locus
1997
Newborn Hearing Screening — A Silent Revolution
2006 Standout
Haploview: analysis and visualization of LD and haplotype maps
2004 Standout
Whole Genome Sequences of a Male and Female Supercentenarian, Ages Greater than 114 Years
2012
Estimation of apolipoprotein E genotype-specific relative mortality risks from the distribution of genotypes in centenarians and middle-aged men: Apolipoprotein E gene is a ?frailty gene,? not a ?longevity gene?
2000
Amyotrophic lateral sclerosis
2011 Standout
β‐Amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?
2002
Reprogramming aging and progeria
2012
Preclinical Evidence of Alzheimer's Disease in Persons Homozygous for the ε4 Allele for Apolipoprotein E
1996
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
2007 Standout
The apolipoprotein E ε2 allele is associated with an increased risk of early‐onset alzheimer's disease and a reduced survival
1995
Inflammaging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans
2006 Standout
Principal components analysis corrects for stratification in genome-wide association studies
2006 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Sex and gender: modifiers of health, disease, and medicine
2020 Standout
ApoE-4 and Age at Onset of Alzheimer's Disease
1997
The effects of apolipoprotein E on non-impaired cognitive functioning: A meta-analysis
2009
Polymorphisms of Drug-Metabolizing Enzymes in Healthy Nonagenarians and Centenarians: Difference at GSTT1 Locus
2001
Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis
2004
Apolipoprotein E in animal models of CNS injury and in alzheimer's disease
1994
Genetic predictors of common disease: Apolipoprotein E genotype as a paradigm
1997
Apolipoprotein E in Alzheimer's disease risk and case detection: A case-control study
1996
Genes Against Aging
2012
Predictive value of apolipoprotein E genotyping in Alzheimer's disease: Results of an autopsy series and an analysis of several combined studies
1994
Inheritance of human longevity in Iceland
2000
Age, APOE and sex: Triad of risk of Alzheimer’s disease
2016
A genetic study of angiotensin I-converting enzyme levels in human semen
1995
Genes and longevity: a genetic-demographic approach reveals sex- and age-specific gene effects not shown by the case–control approach (APOE and HSP70.1 loci)
2006
Power failure: why small sample size undermines the reliability of neuroscience
2013 Standout
Understanding the Odd Science of Aging
2005 Standout
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
A New Statistical Method for Haplotype Reconstruction from Population Data
2001 Standout
Alzheimer's disease
2006 Standout
Genome-Environment Interactions That Modulate Aging: Powerful Targets for Drug Discovery
2011
A multi-modal parcellation of human cerebral cortex
2016 StandoutNature
Heritability of life span in the Old Order Amish
2001
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Molecular mapping of alzheimer‐type dementia in Down's syndrome
1998
Common gene variants, mortality and extreme longevity in humans
2000
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results
1995 Standout
Sequence variation in the human angiotensin converting enzyme
1999
Genetic analysis of ageing: role of oxidative damage and environmental stresses
1996
Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease
2001
The heritability of human longevity: A population-based study of 2872 Danish twin pairs born 1870–1900
1996
Genetics of Alzheimer’s Disease
2014
The Hallmarks of Aging
2013 Standout
Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland
2000 Standout
The Genetic Basis of Complex Human Behaviors
1994 Science
Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians
2004
Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans
1995
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
2009 StandoutNobel
Amyotrophic Lateral Sclerosis
2001 Standout
The Brain's Default Network
2008 Standout
Molecular Mechanisms of Amyloidosis
2003 Standout
The molecular pathology of Alzheimer's disease
1991 Standout
ApoE allele frequencies in Italian sporadic and familial Alzheimer's disease
1994
The p66shc adaptor protein controls oxidative stress response and life span in mammals
1999 StandoutNature
Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line.
1995
Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease
1997 Standout
APOLIPOPROTEIN E ALLELES AS RISK FACTORS IN ALZHEIMER'S DISEASE
1996
Influence of apolipoprotein E genotype on senile dementia of the Alzheimer and Lewy body types. Significance for etiological theories of Alzheimer's disease.
1994
Association of TNF2, a TNF-α Promoter Polymorphism, With Septic Shock Susceptibility and Mortality
1999 Standout
The Free Radical Theory of Aging Matures
1998 Standout
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling
2005 Standout
The remarkable improvements in survival at older ages
1997
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
Genetics of Aging
1997 Science
Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI
2004 Standout
The Genetics of Aging
2001 StandoutNobel
Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development inCaenorhabditis elegans
2008 StandoutNobel
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Broken Limits to Life Expectancy
2002 StandoutScience
Aging, life span, and senescence
1998 StandoutNobel
Alzheimer's Disease Is a Synaptic Failure
2002 StandoutScience
The Genetics of the Amyloidoses
2000
The Future of Genetic Studies of Complex Human Diseases
1996 StandoutScience
Genetic Dissection of Complex Traits
1994 StandoutScience
Angiotensin-converting enzyme and male fertility
1998 StandoutNobel
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III
1997 StandoutNobel
Pathogenic mutations but not polymorphisms in congenital and childhood onset autosomal recessive deafness disrupt the proteolytic activity of TMPRSS3
2003
Correspondence of the brain's functional architecture during activation and rest
2009 Standout
Heteroplasmy for the 1555A>G mutation in the mitochondrial 12S rRNA gene in six Spanish families with non-syndromic hearing loss
2003
Distinct patterns of brain activity in young carriers of the APOE -ε4 allele
2009
Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan
2003
Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region
1996 StandoutScience
Neurodevelopmental Outcomes in Children With Congenital Heart Disease: Evaluation and Management
2012 Standout
Longevity, Genes, and Aging
1996 Science
An ecological study of association between coronary heart disease mortality rates in men and the relative frequencies of common allelic variations in the gene coding for apolipoprotein E
1998
Gene Polymorphisms Predicting High Plasma Levels of Coagulation and Fibrinolysis Proteins
1997
Works of H Rouger being referenced
Genetic associations with human longevity at the APOE and ACE loci
1994 Standout
X-linked Charcot-Marie-Tooth disease with connexin 32 mutations
1998