Citation Impact
Citing Papers
Systematic Analysis of G Protein-Coupled Receptor Gene Expression in Adrenocorticotropin-Independent Macronodular Adrenocortical Hyperplasia Identifies Novel Targets for Pharmacological Control of Adrenal Cushing’s Syndrome
2010
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
International Union of Pharmacology nomenclature of adrenoceptors.
1994 StandoutNobel
Adrenergic α2C-Receptors Modulate the Acoustic Startle Reflex, Prepulse Inhibition, and Aggression in Mice
1998 StandoutNobel
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
2001
Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses
2018 StandoutNobel
Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
2006 StandoutNobel
TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis
2006 Standout
Effect of Cellular Expression of Pleckstrin Homology Domains on Gi-coupled Receptor Signaling
1995 StandoutNobel
Mutagenesis of the catalytic subunit of rabbit muscle protein phosphatase-1
1993
Fructose 2,6-bisphosphate metabolism in Ehrlich ascites tumour cells
1995
Cell-type Specific Targeting of the α2c-Adrenoceptor
2000 StandoutNobel
Go-protein α-Subunits Activate Mitogen-activated Protein Kinase via a Novel Protein Kinase C-dependent Mechanism
1996 StandoutNobel
Cushing's syndrome
2015 Standout
Modulation of the substrate specificity of the polycation‐stimulated protein phosphatase from Xenopus laevis oocytes
1988
Evidence that an α2A-adrenoceptor subtype mediates antinociception in mice
1992
Phosphorylase phosphatase from skeletal muscle membranes
1987
Distinct Pathways of Gi- and Gq-mediated Mitogen-activated Protein Kinase Activation
1995 StandoutNobel
Involvement of α2-adrenoceptors in mediating sympathetic excitation of injured dorsal root ganglion neurons in rats with spinal nerve ligation
1997
Isolation and sequence analysis of a cDNA clone encoding a type‐1 protein phosphatase catalytic subunit: Homology with protein phosphatase 2A
1987
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts
1997 StandoutNobel
Behavioral and receptor binding analysis of the α2-adrenergic agonist, 5-bromo-6 [2-imidazoline-2-YL amino] quinoxaline (UK-14304): evidence for cognitive enhancement at an α2-adrenoceptor subtype
1991
Gβγ Subunits Mediate Mitogen-activated Protein Kinase Activation by the Tyrosine Kinase Insulin-like Growth Factor 1 Receptor
1995 StandoutNobel
Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism
1989 StandoutNature
Gene targeting — homing in on α2-adrenoceptor-subtype function
1997 StandoutNobel
Further characterization of human α2-adrenoceptor subtypes: [3H]RX821002 binding and definition of additional selective drugs
1994
α2 Adrenergic Receptor Subtypes Expressed in Chinese Hamster Ovary Cells Activate Differentially Mitogen-activated Protein Kinase by a p21 Independent Pathway
1995
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission
1999 StandoutNatureNobel
Presynaptic ?2-autoreceptors in mouse heart atria: evidence for the ?2D subtype
1996
Delineation of three pharmacological subtypes of α2‐adrenoceptor in the rat kidney
1991
Pharmacologic and Therapeutic Applications of alpha2-Adrenoceptor Subtypes
1993
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
1997 StandoutNobel
FMRFamide reverses protein phosphorylation produced by 5-HT and cAMP in Aplysia sensory neurons
1989 StandoutNatureNobel
.alpha.- And .beta.-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure
1990
The Role of Sequestration in G Protein-coupled Receptor Resensitization
1997 StandoutNobel
A re-investigation of questionable subclassifications of presynaptic α2-autoreceptors: rat vena cava, rat atria, human kidney and guinea-pig urethra
1997
Effect of Extracellular AMP on Cell Proliferation and Metabolism of Breast Cancer Cell Lines with High and Low Glycolytic Rates
1997
Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1
1995 StandoutNature
Involvement of a calcineurin/ inhibitor-1 phosphatase cascade in hippocampal long-term depression
1994 StandoutNature
Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor
1997 StandoutNobel
Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gβγ-mediated Mitogen-activated Protein Kinase Signaling Pathway
1996 StandoutNobel
Mutational Analysis of the Catalytic Subunit of Muscle Protein Phosphatase-1
1996
Expression of the A subunit of protein phosphatase 2A and characterization of its interactions with the catalytic and regulatory subunits.
1992
The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity.
1995 StandoutNobel
Conversion of a phosphoseryl/threonyl phosphatase into a phosphotyrosyl phosphatase
1988
Cardiac contractile protein phosphatases. Purification of two enzyme forms and their characterization with subunit-specific antibodies.
1987
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Dephosphorylation of the beta 2-adrenergic receptor and rhodopsin by latent phosphatase 2.
1988 StandoutNobel
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution.
1986 StandoutNobel
A mutant of protein phosphatase-1 that exhibits altered toxin sensitivity.
1994
Synergistic phosphorylation and activation of ATP-Mg-dependent phosphoprotein phosphatase by F A/GSK-3 and casein kinase II (PC0.7).
1984
Phosphorylation of the mammalian beta-adrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulatory guanine nucleotide regulatory protein.
1985 StandoutNobel
The kinetics of tyrosine phosphorylation by the purified epidermal growth factor receptor kinase of A-431 cells.
1983 StandoutNobel
Protein (serine and threonine) phosphate phosphatases
1984
Rabbit muscle glycogen-bound phosphoprotein phosphatases: Substrate specificities and effects of inhibitor-1
1983
Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.
1994 StandoutNobel
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase.
1982 StandoutNobel
Cardiovascular Regulation in Mice Lacking α 2 -Adrenergic Receptor Subtypes b and c
1996 StandoutScienceNobel
Purification of the major protein-tyrosine-phosphatases of human placenta.
1988 StandoutNobel
Inactivation and reactivation of phosphoprotein phosphatase
1982
Binding of G protein beta gamma-subunits to pleckstrin homology domains.
1994 StandoutNobel
Characterization of the major protein-tyrosine-phosphatases of human placenta.
1988 StandoutNobel
Mutation of the α2A-Adrenoceptor Impairs Working Memory Performance and Annuls Cognitive Enhancement by Guanfacine
2002 StandoutNobel
Phosphorylase phosphatase. Comparison of active forms using peptide substrates.
1988 StandoutNobel
The human colon carcinoma cell lines HT-29 and Caco-2: Two in vitro models for the study of intestinal differentiation
1986
A major phosphotyrosyl-protein phosphatase from bovine heart is associated with a low-molecular-weight acid phosphatase
1985
Purification and characterization of two inactive/latent protein phosphatases from pig brain.
1986
Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts.
1993
An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: Role in tumor cell glycolysis and the Warburg effect
1999
Antinociceptive Action of Nitrous Oxide Is Mediated by Stimulation of Noradrenergic Neurons in the Brainstem and Activation of α2BAdrenoceptors
2000 StandoutNobel
The protein phosphatases involved in cellular regulation
1985
A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cells.
1990 Standout
Studies and Perspectives of Protein Kinase C
1986 StandoutScience
Phosphorylase phosphatase. Interconversion of active and inactive forms.
1984 StandoutNobel
Protein Phosphatases: Properties and Role in Cellular Regulation
1983 Science
Dephosphorylation of skeletal muscle phosphorylase, glycogen synthase, and phosphorylase kinase β-subunit by a Mn2+-activated protein phosphatase
1982 StandoutNobel
Printing Proteins as Microarrays for High-Throughput Function Determination
2000 StandoutScience
Cyclic AMP-dependent protein kinase closes the serotonin-sensitive K+channels of Aplysia sensory neurones in cell-free membrane patches
1985 StandoutNatureNobel
Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal.
1990 StandoutNobel
The Protein Phosphatases Involved in Cellular Regulation. 1. Classification and Substrate Specificities
1983
Regulatory Mechanisms in the Control of Protein Kinase
1982
Phosphoprotein phosphatase inhibitor‐2 is phosphorylated at both serine and threonine residues in mouse diaphragm
1985
Purification of MPF from starfish: Identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation
1989 StandoutNobel
Alpha 2A adrenergic receptors inhibit cAMP accumulation in embryonic stem cells which lack Gi alpha 2.
1994
The protein phosphatases involved in cellular regulation. Identification of the inhibitor-2 phosphatases in rabbit skeletal muscle
1984
Stimulation of protein phosphatase activity by insulin and growth factors in 3T3 cells.
1988 StandoutNobel
Works of H. Paris being referenced
Alpha 2 adrenoceptors regulate proliferation of human intestinal epithelial cells
2000
Interactions of full and partial agonists with HT29 cell alpha 2-adrenoceptor: comparative study of [3H]UK-14,304 and [3H]clonidine binding.
1989
Summary of the ASPET-sponsored Colloquium: Alpha-2 adrenergic receptors: structure, function, and therapeutic implications, October 25-27, 1995.
1996
Alpha-2 adrenoceptor in rat jejunum epithelial cells: characterization with [3H]RX821002 and distribution along the villus-crypt axis.
1990
Hormonal control of fructose 2,6-bisphosphate concentration in the HT29 human colon adenocarcinoma cell line α2-adrenergic agonists counteract effect of vasoactive intestinal peptide
1986
The phosphoprotein phosphatases: properties of the enzymes involved in the regulation of glycogen metabolism.
1980
Growth‐related variation of α2‐adrenergic receptivity in the HT 29 adenocarcinoma cell‐line from human colon
1985
Regulation of the alpha 2A-adrenergic receptor in the HT29 cell line. Effects of insulin and growth factors
1991
Isolation and characterization of rabbit skeletal muscle protein phosphatases C-I and C-II.
1984
Coupling of the α2-adrenergic receptor to the inhibitory G-protein Gi and adenylate cyclase in HT29 cells
1993
Isolation and characterization of a high molecular weight protein phosphatase from rabbit skeletal muscle.
1984
Dephosphorylation of rabbit skeletal muscle phosphorylase kinase. Evidence against the operation of the “second-site phosphorylation” mechanism of regulation.
1981
Binding of [3H]idazoxan and of its methoxy derivative [3H] RX821002 in human fat cells: [3H]idazoxan but not [3H] RX821002 labels additional non-alpha 2-adrenergic binding sites.
1990
The insulin-secreting cell line, RINm5F, expresses an alpha-2D adrenoceptor and nonadrenergic idazoxan-binding sites.
1992
Activity of enzymes related to carbohydrate metabolism in the HT 29 colon adenocarcinoma cell line and tumor
1984