Citation Impact
Citing Papers
Highly Recurrent TERT Promoter Mutations in Human Melanoma
2013 StandoutScience
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Targeting of Cyclic AMP Degradation to β 2 -Adrenergic Receptors by β-Arrestins
2002 StandoutScienceNobel
PDE4 cAMP-specific phosphodiesterases
2001
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNatureNobel
Molecular mechanisms underlying ErbB2/HER2 action in breast cancer
2000
Therapeutic siRNA: state of the art
2020
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection
2021
American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer
2007 Standout
Linking CRISPR-Cas9 interference in cassava to the evolution of editing-resistant geminiviruses
2019
Structural elements of Gα subunits that interact with Gβγ, receptors, and effectors
1993
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Telomerase as a therapeutic target for malignant gliomas
2002
Gout-associated uric acid crystals activate the NALP3 inflammasome
2006 StandoutNature
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
mRNA Is an Endogenous Ligand for Toll-like Receptor 3
2004 StandoutNobel
Oncogenic kinase signalling
2001 StandoutNature
Bacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral research and treatment
2015
Rapid gating and anion permeability of an intracellular aquaporin
1999 StandoutNatureNobel
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Molecular characterization of a peripheral receptor for cannabinoids
1993 StandoutNature
Targeting hepatitis B virus cccDNA by CRISPR/Cas9 nuclease efficiently inhibits viral replication
2015
A CRISPR toolbox to study virus–host interactions
2017
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Telomere states and cell fates
2000 StandoutNatureNobel
Enabling functional genomics with genome engineering
2015
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
The Hallmarks of Cancer
2000 Standout
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells.
2000
NMR structure of a receptor-bound G-protein peptide
1993 Nature
Cyclic AMP-dependent Activation of Rap1b
1995
Papillomaviruses and cancer: from basic studies to clinical application
2002 StandoutNobel
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase
1998 StandoutNobel
Membrane Fusion
2003 StandoutNobel
Mechanisms of inflammation in gout
2005
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Switching and Signaling at the Telomere
2001 StandoutNobel
Angiogenesis and Blood Vessel Invasion as Prognostic Indicators for Node-Negative Breast Cancer
2001
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNobel
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Dual gRNAs guided CRISPR/Cas9 system inhibits hepatitis B virus replication
2015
A Genome-wide CRISPR Screen Identifies ZCCHC14 as a Host Factor Required for Hepatitis B Surface Antigen Production
2019
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
Gene expression and hypoxia in breast cancer
2011
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Clinical Utility of Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor—1 Determination in Primary Breast Cancer Tissue for Individualized Therapy Concepts
2002
Receptor Up-regulation, Internalization, and Interconverting Receptor States
1996
Creation of human tumour cells with defined genetic elements
1999 StandoutNature
Inhibition of telomerase limits the growth of human cancer cells
1999
Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gβγ-mediated Mitogen-activated Protein Kinase Signaling Pathway
1996 StandoutNobel
Expression of TERT in early premalignant lesions and a subset of cells in normal tissues
1998
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
1999 StandoutNobel
Inhibition of hepatitis B virus by the CRISPR/Cas9 system via targeting the conserved regions of the viral genome
2015
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade
2008 StandoutNobel
Mapping of the mastoparan-binding site on G proteins. Cross-linking of [125I-Tyr3,Cys11]mastoparan to Go
1991
Direct activation of TERT transcription by c-MYC
1999
Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits.
1993 StandoutNobel
RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts.
1993
Genes and pathways downstream of telomerase in melanoma metastasis
2006 StandoutNobel
Ku is associated with the telomere in mammals
1999 StandoutNobel
Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.
1994 StandoutNobel
Coat Proteins and Vesicle Budding
1996 StandoutScienceNobel
Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP
1998 StandoutNature
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization
1998
G i regulation of secretory vesicle swelling examined by atomic force microscopy
1997
The disaggregation theory of signal transduction revisited: further evidence that G proteins are multimeric and disaggregate to monomers when activated.
1993 StandoutNobel
Transient increase in phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophils
1989
G-protein ligands inhibit in vitro reactions of vacuole inheritance.
1994
Multiple GTP-binding proteins participate in clathrin-coated vesicle-mediated endocytosis.
1993
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
2001 StandoutNobel
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Transcriptional Activation of the Telomerase hTERT Gene by Human Papillomavirus Type 16 E6 Oncoprotein
2001
Lipid modifications of G proteins: alpha subunits are palmitoylated.
1993 StandoutNobel
Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene.
1999
Receptor regulation of G-protein palmitoylation.
1994 StandoutNobel
Antibodies to the alpha q subfamily of guanine nucleotide-binding regulatory protein alpha subunits attenuate activation of phosphatidylinositol 4,5-bisphosphate hydrolysis by hormones.
1991
Structure and mechanism of the G protein-coupled receptor kinases.
1993 StandoutNobel
Microvessel Density as a Prognostic Factor in Women with Breast Cancer
2004
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of H. Mueller being referenced
The potency and kinetics of the beta-adrenergic receptors on human neutrophils.
1988
Markers of tumor angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients.
1998
Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease
2014
Liver-Targeted Anti-HBV Single-Stranded Oligonucleotides with Locked Nucleic Acid Potently Reduce HBV Gene Expression In Vivo
2018
Selective Regulation of Steroid Receptor Expression in MCF-7 Breast Cancer Cells by a Novel Member of the Heregulin Family
1995
PAPD5/7 Are Host Factors That Are Required for Hepatitis B Virus RNA Stabilization
2018
Rap1A is a substrate for cyclic AMP-dependent protein kinase in human neutrophils
1991
Three States for the Formyl Peptide Receptor on Intact Cells
1989
Expression profile of the putative catalytic subunit of the telomerase gene.
1998
Mastoparan interacts with the carboxyl terminus of the alpha subunit of Gi.
1990
Neutrophil activation by inflammatory microcrystals of monosodium urate monohydrate utilizes pertussis toxin-insensitive and -sensitive pathways.
1990