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Citing Papers
Adenoviral Transfer of the Viral IL-10 Gene Periarticularly to Mouse Paws Suppresses Development of Collagen-Induced Arthritis in Both Injected and Uninjected Paws
1999
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
2005 StandoutNatureNobel
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
1997 StandoutNature
Inflammation and cancer
2002 StandoutNature
A novel domain within the 55 kd TNF receptor signals cell death
1993
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
1994
Protein-tyrosine Phosphatase Inhibitors Block Tumor Necrosis Factor-dependent Activation of the Nuclear Transcription Factor NF-kB
1995
The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
1995 Standout
Tumor necrosis factor, cancer and anticancer therapy
2004
CD4+ T-cell subsets in autoimmunity
1997
Regulatory T Cells
2000 StandoutNobel
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
1994 StandoutNature
Soluble tumor necrosis factor receptors in human inflammatory synovial fluids
1993
Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes
1993 Nature
Biphasic effect of interferon‐γ in murine collagen‐induced arthritis
1995
Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis.
1995
Tumor necrosis factor and its receptors in human ovarian cancer. Potential role in disease progression.
1993
Localization of tumor necrosis factor receptors in the synovial tissue and cartilage‐pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor α
1992
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
1992 StandoutNature
Tumor Necrosis Factor-α Blockade: A Novel Therapy for Rheumatic Disease
2002
Developmental regulation of MHC class II transport in mouse dendritic cells
1997 StandoutNatureNobel
Two inhibitors of pro‐inflammatory cytokine release, interleukin‐10 and interleukin‐4, have contrasting effects on release of soluble p75 tumor necrosis factor receptor by cultured monocytes
1994
Cytokine Modifiers
1998
The stress-activated protein kinase subfamily of c-Jun kinases
1994 StandoutNature
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Cytokine Pathways and Joint Inflammation in Rheumatoid Arthritis
2001 Standout
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation
1993
Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints
1992
Role of TNF–TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications
2018
Seeing double: Crystal structures of the type I TNF receptor
1996
Inhibition of the production and effects of interleukins‐1 and tumor necrosis factor α in rheumatoid arthritis
1995
Cell-mediated cytotoxicity
1993 StandoutNobel
Atherosclerosis — An Inflammatory Disease
1999 Standout
The Fas Death Factor
1995 StandoutScience
Origin and physiological roles of inflammation
2008 StandoutNature
The type I interleukin‐1 receptor acts in series with tumor necrosis factor (TNF) to induce arthritis in TNF‐transgenic mice
1995
Disrupted dichotomous intracellular control of human papillomavirus infection in cancer of the cervix
1994 StandoutNobel
Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor
1993
Adjunctive therapy in sepsis: a critical analysis of the clinical trial programme
1999
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
1998 StandoutNature
Two tumour necrosis factor receptors: structure and function
1995
Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-κB
1996
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
1991 Standout
Points of control in inflammation
2002 StandoutNature
Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases
1992
Critical role of Vα14+ natural killer T cells in the innate phase of host protection against Streptococcus pneumoniae infection
2003
Tumor necrosis factor Characterization at the molecular, cellular and in vivo level
1991
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice
1994 Nature
Crystallographic Analysis of the Recognition of a Nuclear Localization Signal by the Nuclear Import Factor Karyopherin α
1998 StandoutNobel
Cancer-related inflammation
2008 StandoutNature
Inhibition of death receptor signals by cellular FLIP
1997 StandoutNature
Langerhans cells require signals from both tumour necrosis factor‐α and interleukin‐1β for migration
1997
Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics
2008
The immunopathogenesis of sepsis
2002 StandoutNature
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
HMG-1 as a Late Mediator of Endotoxin Lethality in Mice
1999 StandoutScience
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Tumor necrosis factor receptor p75 mediates cell-specific activation of nuclear factor kappa B and induction of human cytomegalovirus enhancer.
1994
The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor
1998
The p70 tumor necrosis factor receptor mediates cytotoxicity
1992
Expression of functional CD40 by vascular endothelial cells.
1995
ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS
1996 Standout
Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: A comparative study using anti-TNFα, anti-IL-1α/β and IL-1Ra
2008
Anti-TNFα Therapy of Rheumatoid Arthritis: What Have We Learned?
2001
Maintenance of NF-kappa B activity is dependent on protein synthesis and the continuous presence of external stimuli.
1991
Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor.
1991
The two different receptors for tumor necrosis factor mediate distinct cellular responses.
1991
Amelioration of established murine collagen-induced arthritis with anti-IL-1 treatment
1994
Essential roles of tumor necrosis factor receptor p55 in liver metastasis of intrasplenic administration of colon 26 cells.
2002
NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation
1998 StandoutScience
Identification of a Protein with Homology to hsp90 That Binds the Type 1 Tumor Necrosis Factor Receptor
1995
Death Receptors: Signaling and Modulation
1998 StandoutScience
Essential Role of Neutrophils in the Initiation and Progression of a Murine Model of Rheumatoid Arthritis
2001
Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1
2000 StandoutScience
Tumour necrosis factor-alpha is required for accumulation of dendritic cells in draining lymph nodes and for optimal contact sensitization.
1995
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific.
1991
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer.
1994 StandoutNobel
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Thymocyte-Thymic Epithelial Cell Interaction Leads to High-Level Replication of Human Immunodeficiency Virus Exclusively in Mature CD4+CD8−CD3+Thymocytes: a Critical Role for Tumor Necrosis Factor and Interleukin-7
1999 StandoutNobel
Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.
1995 Standout
An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death
1996 StandoutScienceNobel
Successful therapy of collagen-induced arthritis with TNF receptor-IgG fusion protein and combination with anti-CD4.
1995
Ceramide Inhibits Antigen Uptake and Presentation by Dendritic Cells
1996
Albumin inhibits neutrophil spreading and hydrogen peroxide release by blocking the shedding of CD43 (sialophorin, leukosialin)
1993
The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
1996
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
Hematopoietic growth factors and their receptors in acute leukemia
1993
Chimeric tumor necrosis factor receptors with constitutive signaling activity.
1995 StandoutNobel
Aggregation of the intracellular domain of the type 1 tumor necrosis factor receptor defined by the two-hybrid system.
1994
Tumour necrosis factor receptor distribution in human lymphoid tissue.
1991
A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels
1998 StandoutNobel
Differential regulation of the JE gene encoding the monocyte chemoattractant protein (MCP-1) in cervical carcinoma cells and derived hybrids
1994 StandoutNobel
Single dose of anti–CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance
2010 StandoutNobel
Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System
1992 Science
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
1998
Recombinant 55-kDa tumor necrosis factor (TNF) receptor. Stoichiometry of binding to TNF alpha and TNF beta and inhibition of TNF activity.
1991
Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis.
1994
Suppression of TNF-α-Induced Apoptosis by NF-κB
1996 StandoutScience
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
1999
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
T-cell subsets in autoimmunity
1993
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB
1996 StandoutScience
Works of H Loetscher being referenced
55-kd Tumor Necrosis Factor Receptor Is Expressed by Human Keratinocytes and Plays a Pivotal Role in Regulation of Human Keratinocyte ICAM-1 Expression
1991
Differential responses of fibroblasts from wild-type and TNF-R55-deficient mice to mouse and human TNF-alpha activation.
1994
Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma.
1992
Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies.
1990
A human tumor necrosis factor p75 receptor agonist stimulates in vitro T cell proliferation but does not produce inflammation or shock in the baboon.
1996
Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor.
1992
Both tumor necrosis factor receptor types mediate proliferative signals in human mononuclear cell activation
1992
Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55.
1993
Protective effect of 55- but not 75-kD soluble tumor necrosis factor receptor-immunoglobulin G fusion proteins in an animal model of gram-negative sepsis.
1994
Tumor necrosis factor: receptors and inhibitors.
1991