Citation Impact
Citing Papers
Pathophysiology of Migraine: A Disorder of Sensory Processing
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Descending control of persistent pain: inhibitory or facilitatory?
2004
The antinociceptive effect of tramadol in the formalin test is mediated by the serotonergic component
2002
DECONSTRUCTING ENDOGENOUS PAIN MODULATIONS
2005
Introducing a placebo needle into acupuncture research
1998 Standout
Endogenous opioid-mediated inhibition of putative pain-modulating neurons in rat rostral ventromedial medulla
1996
Coping with chronic pain: a critical review of the literature
1991 Standout
Supraspinal cholecystokinin may drive tonic descending facilitation mechanisms to maintain neuropathic pain in the rat
2000
Roles for Pain Modulatory Cells during Micturition and Continence
2005
The benzodiazepine inverse agonist DMCM as an unconditional stimulus for fear-induced analgesia: Implications for the role of GABA-sub(A ) receptors in fear-related behavior.
1992
Human brain mechanisms of pain perception and regulation in health and disease
2005 Standout
Neural mechanism underlying acupuncture analgesia
2008 Standout
Ventromedial medulla: Pain modulation and beyond
2005
Brain stem activation in spontaneous human migraine attacks
1995 Standout
The medullary dorsal reticular nucleus facilitates pain behaviour induced by formalin in the rat
1999
GABAergic modulation of descending inhibitory systems from the rostral ventromedial medulla (RVM). Dose-response analysis of nociception and neurological deficits
2001
Descending control of pain
2002 Standout
Relationship between electroacupuncture analgesia and descending pain inhibitory mechanism of nucleus raphe magnus
1986
A Fear-Avoidance Beliefs Questionnaire (FABQ) and the role of fear-avoidance beliefs in chronic low back pain and disability
1993 Standout
Cognitive modulation of pain: how do attention and emotion influence pain processing?
2002 Standout
Basal release of Met-enkephalin and neurotensin in the ventrolateral periaqueductal gray matter of the rat: a microdialysis study of antinociceptive circuits
1995
A cellular mechanism for the antinociceptive effect of a kappa opioid receptor agonist
2001
Descending facilitatory modulation of a behavioral nociceptive response by stimulation in the adult rat anterior cingulate cortex
2000
Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice
2007 StandoutNobel
Endogenous opioids acting at a medullary μ-opioid receptor contribute to the behavioral antinociception produced by GABA antagonism in the midbrain periaqueductal gray
1996
The role of excitatory amino acid transmission within the rostral ventromedial medulla in the antinociceptive actions of systemically administered morphine
1999
Methods Used to Evaluate Pain Behaviors in Rodents
2017 Standout
Is serotonin hyperalgesic or analgesic?
2006
Transient receptor potential channels: targeting pain at the source
2008 StandoutNobel
Association of serotonin-like immunoreactive axons with nociceptive projection neurons in the caudal spinal trigeminal nucleus of the rat
1997
Context, time, and memory retrieval in the interference paradigms of Pavlovian learning.
1993 Standout
Interference with GABA transmission in the rostral ventromedial medulla: Disinhibition of off-cells as a central mechanism in nociceptive modulation
1994
Reward Circuitry Activation by Noxious Thermal Stimuli
2001
Elevation of Endocannabinoid Levels in the Ventrolateral Periaqueductal Grey through Inhibition of Fatty Acid Amide Hydrolase Affects Descending Nociceptive Pathways via Both Cannabinoid Receptor Type 1 and Transient Receptor Potential Vanilloid Type-1 Receptors
2006
Mechanisms of Actions of Inhaled Anesthetics
2003 Standout
Serotonergic, cholinergic and nociceptive inhibition or excitation of raphe magnus neurons in barbiturate-anesthetized rats
1993
The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders
2007 Standout
Response properties of neurons in the rostroventromedial medulla of neuropathic rats: attempted modulation of responses by [1DMe]NPYF, a neuropeptide FF analogue
2001
Tonic Endovanilloid Facilitation of Glutamate Release in Brainstem Descending Antinociceptive Pathways
2007
Irritable bowel syndrome
2016 Standout
The medullary dorsal reticular nucleus facilitates acute nociception in the rat
1996
Beautiful Faces Have Variable Reward Value
2001 Standout
Direct evidence of an extensive GABAergic innervation of the spinal dorsal horn by fibres descending from the rostral ventromedial medulla
1996
Animal models of pain: progress and challenges
2009
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Descending facilitatory control of mechanically evoked responses is enhanced in deep dorsal horn neurones following peripheral nerve injury
2004
Physiology of Pain
2000
Chronic back pain and rheumatoid arthritis: Predicting pain and disability from cognitive variables
1988
The behavioural importance of dynamically activated descending inhibition from the nucleus reticularis gigantocellularis pars alpha
2001
Hyperalgesia during Naloxone-Precipitated Withdrawal from Morphine Is Associated with Increased On-Cell Activity in the Rostral Ventromedial Medulla
1990
An analgesia circuit activated by cannabinoids
1998 Nature
Excitatory amino acid antagonists in the rostral ventromedial medulla inhibit mesencephalic morphine analgesia in rats
1996
Comparison of the antinociceptive effect of morphine and glutamate at coincidental sites in the periaqueductal gray and medial medulla in rats
1989
Bad news from the brain: descending 5-HT pathways that control spinal pain processing
2004
Depletion of endogenous spinal 5-HT attenuates the behavioural hypersensitivity to mechanical and cooling stimuli induced by spinal nerve ligation
2006
Physiological and anatomic evidence for functional subclasses of serotonergic raphe magnus cells
2001
Central mechanisms of pain modulation
1999
State-dependent opioid control of pain
2004
The rewards of music listening: Response and physiological connectivity of the mesolimbic system
2005 Standout
Persistent postsurgical pain: risk factors and prevention
2006 Standout
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
The molecular logic of endocannabinoid signalling
2003 Standout
Antinociception and modulation of rostral ventromedial medulla neuronal activity by local microinfusion of a cannabinoid receptor agonist
2004
Functional activity mapping of the rat brainstem during formalin-induced noxious stimulation
1991
The formalin test: an evaluation of the method
1992 Standout
Clinical Pharmacology of Tramadol
2004 Standout
Effects of intravenous phenylephrine on blood pressure, nociception, and neural activity in the rostral ventral medulla in rats
1996
GABAergic modulation of the analgesic effects of morphine microinjected in the ventral periaqueductal gray matter of the rat
1987
Descending control of nociception: Specificity, recruitment and plasticity
2008
Activation of brainstem N-methyl-D-aspartate receptors is required for the analgesic actions of morphine given systemically
2001
Neurotensin and pain modulation
2006
A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins
2017
Serotonin, tryptophan metabolism and the brain-gut-microbiome axis
2014 Standout
The biopsychosocial approach to chronic pain: Scientific advances and future directions.
2007 Standout
Induction of pain facilitation by sustained opioid exposure: relationship to opioid antinociceptive tolerance
2003
Histamine-induced modulation of nociceptive responses
1994
Spinal and Supraspinal Mechanisms of Neuropathic Pain
2000
Diencephalic and brainstem mechanisms in migraine
2011
Brainstem modulation of pain during sleep and waking
2003
Critical anthropomorphic evaluation and treatment of postoperative pain in rats and mice
2003 StandoutNobel
Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
2014 Standout
Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity
2009 Standout
What can in vivo electrophysiology in animal models tell us about mechanisms of anaesthesia?
2002
A Comparison of Visceral and Somatic Pain Processing in the Human Brainstem Using Functional Magnetic Resonance Imaging
2005
The integration of negative affect, pain and cognitive control in the cingulate cortex
2011 Standout
Chronic pain and medullary descending facilitation
2002
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Neuropathic Pain Activates the Endogenous κ Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance
2004 StandoutNobel
Anatomy and physiology of a nociceptive modulatory system
1985
Cortico-NRM Influences on Trigeminal Neuronal Sensation
2008
Activation of Serotonergic Neurons in the Raphe Magnus Is Not Necessary for Morphine Analgesia
1998
Animal Models of Nociception
2001
A Role of TRPA1 in Mechanical Hyperalgesia is Revealed by Pharmacological Inhibition
2007 StandoutNobel
Circuitry Underlying AntiOpioid Actions of Orphanin FQ in the Rostral Ventromedial Medulla
1997
Chapter 1 Anatomy and physiology of descending control of nociceptive responses of dorsal horn neurons: comprehensive review
1988
Serotonergic Raphe Magnus Cells That Respond to Noxious Tail Heat Are Not on or off Cells
2000
Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission
1986
Somatodendritic and axonal anatomy of intracellularly labeled serotonergic neurons in the rat medulla.
1997
Physiological Properties of Raphe Magnus Neurons During Sleep and Waking
1999
Interactions between the lateral hypothalamus and the periaqueductal gray
1988
Physiological Identification of Pontomedullary Serotonergic Neurons in the Rat
1997
Tonic Descending Facilitation from the Rostral Ventromedial Medulla Mediates Opioid-Induced Abnormal Pain and Antinociceptive Tolerance
2001
Enhanced Evoked Excitatory Transmitter Release in Experimental Neuropathy Requires Descending Facilitation
2003
How do you feel? Interoception: the sense of the physiological condition of the body
2002 Standout
Noradrenergic input to nociceptive modulatory neurons in the rat rostral ventromedial medulla
1997
Sensory suppression during feeding
2005
Interactions between cardiovascular and pain regulatory systems
1984
Descending Pathways in Motor Control
2008 Standout
SEROTONERGIC Pontomedullary Neurons Are Not Activated by Antinociceptive Stimulation in the Periaqueductal Gray
1997
Supraspinal contributions to hyperalgesia
1999
Neuropathic Pain: From Mechanisms to Treatment
2020 Standout
Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in βArrestin-2 Knock-Out Mice
2002 StandoutNobel
Genetic contributions to generalized arousal of brain and behavior
2003 StandoutNobel
Morphine microinjected into the periaqueductal gray has differential effects on 3 classes of medullary neurons
1986
Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.
2002 StandoutNobel
A Comprehensive Review of the Placebo Effect: Recent Advances and Current Thought
2007 Standout
Brainstem Control of Spinal Pain-Transmission Neurons
1978 Standout
Lesions of the periaqueductal gray and rostral ventromedial medulla disrupt antinociceptive but not cardiovascular aversive conditional responses
1994
Circuitry Underlying Antiopioid Actions of Cholecystokinin Within the Rostral Ventromedial Medulla
2001
Animal models of nociception.
2001
Inhibition of Neuropathic Pain by Selective Ablation of Brainstem Medullary Cells Expressing the μ-Opioid Receptor
2001
Time-Dependent Descending Facilitation from the Rostral Ventromedial Medulla Maintains, But Does Not Initiate, Neuropathic Pain
2002
Somatodendritic and axonal anatomy of intracellularly labeled serotonergic neurons in the rat medulla
1997
Works of H. L. Fields being referenced
Direct and indirect actions of morphine on medullary neurons that modulate nociception
1992
The density and distribution of serotonergic appositions onto identified neurons in the rat rostral ventromedial medulla
1995
The activity of neurons in the rostral medulla of the rat during withdrawal from noxious heat
1983
Serotonin immunoreactivity is contained in one physiological cell class in the rat rostral ventromedial medulla
1994
Three bulbospinal pathways from the rostral medulla of the cat: an autoradiographic study of pain modulating systems
1979
Physiology Evidence that disinhibition of brain stem neurones contributes to morphine analgesia
1985
Differential effect of morphine on three classes of medullary neurons
1984
Evidence for two classes of nociceptive modulating neurons in the periaqueductal gray
1987