Citation Impact
Citing Papers
Computational protein design enables a novel one-carbon assimilation pathway
2015 StandoutNobel
An Engineered Microbial Platform for Direct Biofuel Production from Brown Macroalgae
2012 StandoutScienceNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
The crystal structure of plant acetohydroxy acid isomeroreductase complexed with NADPH, two magnesium ions and a herbicidal transition state analog determined at 1.65Aresolution
1997
Effect of the RC gene product on constitutive enzyme synthesis
1971
Crystal Structure of lac Repressor Core Tetramer and Its Implications for DNA Looping
1995 StandoutScienceNobel
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication
1990 StandoutNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
Biosynthetically Directed Fractional 13C-labeling of Proteinogenic Amino Acids. An Efficient Analytical Tool to Investigate Intermediary Metabolism
1995
De Novo Designed Proteins from a Library of Artificial Sequences Function in Escherichia Coli and Enable Cell Growth
2011
Support of1H NMR assignments in proteins by biosynthetically directed fractional13C-labeling
1992 StandoutNobel
The Shikimate Pathway — A Metabolic Tree with Many Branche
1990
Allosteric Receptors after 30 Years
1998
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*
1966 Standout
ROLE OF VALYL-sRNA SYNTHETASE IN ENZYME REPRESSION
1965
Amino Acid Biosynthesis in the Spirochete Leptospira : Evidence for a Novel Pathway of Isoleucine Biosynthesis
1974
Distinct Subunits for the Regulation and Catalytic Activity of Aspartate Transcarbamylase*
1965
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
ISOLATION OF THE LAC REPRESSOR
1966 StandoutNobel
CONTROL BY URACIL OF FORMATION OF ENZYMES REQUIRED FOR OROTATE SYNTHESIS
1957
Genetic regulatory mechanisms in the synthesis of proteins
1961 Standout
The Nucleotide Sequence of the lac Operator
1973 StandoutNobel
Initiation, pausing, and termination of transcription in the threonine operon regulatory region of Escherichia coli.
1982
AMINO ACID BIOSYNTHESIS IN ESCHERICHIA COLI: ISOTOPIC COMPETITION WITH C14-GLUCOSE
1954
Adenosine Diphosphate-dependent Threonine Dehydrase Activity in Extracts of Clostridium tetanomorphum
1963
Regulation of glutaminase B in Escherichia coli. I. Purification, properties, and cold lability.
1976 StandoutNobel
The Feedback Control Mechanism of Biosynthetic L-Threonine Deaminase by L-Isoleucine
1961
Synthetic Polypeptide Antagonists of the Hypothalamic Luteinizing Hormone Releasing Factor
1972 StandoutScienceNobel
The Primary Structure of Escherichia coli L-Threonine Dehydrogenase
1989
Rétro-inhibition et répression de l'homosérine déshydrogénase d'Escherichia coli
1963
Crystallographic Determination of Symmetry of Aspartate Transcarbamylase
1968 StandoutNatureNobel
Nucleotide sequence of the ilvB promoter-regulatory region: a biosynthetic operon controlled by attenuation and cyclic AMP.
1982
Transformation of Cells in vitro by Viruses
1963 StandoutScienceNobel
Green Fluorescent Protein as a Marker for Gene Expression
1994 StandoutScienceNobel
Properties of a bacterial mutant lacking amino acid control of RNA synthesis
1963
Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II
1990 StandoutNatureNobel
Feed-back Inhibition and Repression of Aspartokinase Activity in Escherichia coli and Saccharomyces cerevisiae
1961
Regulation of intracellular protein breakdown in stringent and relaxed strains of E. coli
1974 StandoutNobel
THE FEEDBACK CONTROL OF SUGAR NUCLEOTIDE BIOSYNTHESIS IN LIVER
1964
Adenosine analogs inhibit adipocyte adenylate cyclase by a GTP-dependent process: basis for actions of adenosine and methylxanthines on cyclic AMP production and lipolysis.
1978 StandoutNobel
Bacteriophage Genes and Bacterial Functions
1962 StandoutScienceNobel
Aqueous Central Cavity in Aspartate Transcarbamylase from Escherichia coli
1973 StandoutScienceNobel
Transfer of yeast telomeres to linear plasmids by recombination
1984 StandoutNobel
A GENETIC LOCUS FOR THE REGULATION OF RIBONUCLEIC ACID SYNTHESIS
1961 StandoutNobel
In vivo and in vitro detection of the leader RNA of the histidine operon of Escherichia coli K-12.
1981
STRINGENT CONTROL IN E. COLI
1979
Inhibitory Effect of Glucose on Enzyme Formation
1956 Nature
DEOXYRIBONUCLEIC ACID-DIRECTED SYNTHESIS OF RIBONUCLEIC ACID BY AN ENZYME FROM ESCHERICHIA COLI
1962 StandoutNobel
Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase
1990 StandoutScience
The E. coli β-lactamase attenuator mediates growth rate-dependent regulation
1981 Nature
Multiple pathways for isoleucine biosynthesis in the spirochete Leptospira
1983
Isoleucine Synthesis by Clostridium sporogenes from Propionate or -Methylbutyrate
1984
Allosteric proteins and cellular control systems
1963 Standout
The Absence of "Heme-Heme" Interactions in Hemoglobin
1969 StandoutScienceNobel
A functional analysis of the rel gene in Escherichia coli
1969
Regulation of Plasma Cholesterol by Lipoprotein Receptors
1981 StandoutScienceNobel
Functional expression of cloned yeast DNA in Escherichia coli.
1977
Amino Acid Biosynthesis in the Halophilic Archaeon Haloarcula hispanica
1999 StandoutNobel
Multivalent translational control of transcription termination at attenuator of ilvGEDA operon of Escherichia coli K-12.
1980
α-Aminoadipate Pathway for the Biosynthesis of Lysine in Lower Eukaryotes
1985
Protein Hydration in Aqueous Solution
1991 StandoutScienceNobel
Unusual pathway of isoleucine biosynthesis in Methanobacterium thermoautotrophicum
1983
The Catalytic and Regulatory Properties of Enzymes
1968
Unequal crossing over in the ribosomal DNA of Saccharomyces cerevisiae
1980 StandoutNatureNobel
EFFECTS OF FEEDBACK MODIFIERS ON THE STATE OF AGGREGATION OF HOMOSERINE DEHYDROGENASE OF RHODOSPIRILLUM RUBRUM
1964
Sequence and structure of D-glyceraldehyde 3-phosphate dehydrogenase from Bacillus stearothermophilus
1977 StandoutNatureNobel
CONTROL OF PYRIMIDINE BIOSYNTHESIS IN ESCHERICHIA COLI BY A FEED-BACK MECHANISM
1956
The nucleotide sequence ofaroG, the gene for 3-deoxy-D-arabinobeptulosonate-7-phosphate synthetase (phe) inEscherichia coliK12
1982
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
2013 StandoutNobel
Uses of lac fusions for the study of biological problems
1985
Messenger ribonucleic acid of the lipoprotein of the Escherichia coli outer membrane. II. The complete nucleotide sequence.
1980
The Control of Ribonucleic Acid Synthesis in Escherichia coli
1969
On the nature of allosteric transitions: A plausible model
1965 Standout
Cloning, partial sequencing, and in vitro transcription of the gene for alanine tRNA synthetase.
1981
Isolation and Partial Characterization of Escherichia coli Mutants with Altered Glycyl Transfer Ribonucleic Acid Synthetases
1970 StandoutNobel
Isoleucine Auxotrophy as a Consequence of a Mutationally Altered Isoleucyl-Transfer Ribonucleic Acid Synthetase
1971 StandoutNobel
Detecting and dissecting metabolic fluxes using biosynthetic fractional 13C labeling and two-dimensional NMR spectroscopy
1996 StandoutNobel
The Control of Ribonucleic Acid Synthesis in Escherichia coli
1969
Characterization of an Extremely Large, Ligand-Induced Conformational Change in Plasminogen
1990 StandoutScienceNobel
Studies on Receptor-mediated Activation of Adenylyl Cyclases
1974
Control of leu operon expression in Escherichia coli by a transcription attenuation mechanism
1981
MSI and MSII made on Ribosome in Idling Step of Protein Synthesis
1972 StandoutNatureNobel
Regulation of Cholesterol Metabolism
1970
Regulation of Enzyme Activity by Specific Reversal of Feedback Inhibition
1963 Science
DNA sequence of the gene for the outer membrane lipoprotein of E. coli: an extremely AT-rich promoter
1979
Benzaldehyde lyase, a novel thiamine PPi-requiring enzyme, from Pseudomonas fluorescens biovar I
1989
A Revised Medium for Rapid Growth and Bio Assays with Tobacco Tissue Cultures
1962 Standout
The Regulation of Activity of Phosphoribosylpyrophosphate Amidotransferase by Purine Ribonucleotides: A Potential Feedback Control of Purine Biosynthesis
1959
Nucleotide sequence of the argF regulatory region of Escherichia coli K-12
1981
A suppressor mutation in the nematode acting on specific alleles of many genes
1978 StandoutNatureNobel
Regulation of Cholesterol Metabolism
1970
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
End-product inhibition of yeast phosphofructokinase by ATP
1963
Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts
1983 StandoutNobel
Allosteric Interactions on Biosynthetic L-threonine Deaminase from E. coli K12
1963
Biosynthetically Directed Fractional 13C-labeling of Proteinogenic Amino Acids. An Efficient Analytical Tool to Investigate Intermediary Metabolism
1995
Compilation and analysis ofEscherichia colipromoter DNA sequences
1983 Standout
Homoserine Dehydrogenase of Rhodospirillum rubrum
1965
Mutants of Escherichia coli with an Altered Tyrosyl-Transfer Ribonucleic Acid Synthetase
1969
Receptor-Mediated Control of Cholesterol Metabolism
1976 StandoutScienceNobel
New Features of the Regulation of the Tryptophan Operon
1975 Science
Recalibrated linkage map of Escherichia coli K-12
1976
Mechanisms of Suppression
1973
Role of Isoleucyl-Transfer Ribonucleic Acid Synthetase in Ribonucleic Acid Synthesis and Enzyme Repression in Yeast
1969 StandoutNobel
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Nucleotide sequence of yeast LEU2 shows 5′-noncoding region has sequences cognate to leucine
1982
Yeast transformation: a model system for the study of recombination.
1981 StandoutNobel
Revised linkage map of Escherichia coli
1967
Roles of amino acid activating enzymes in cellular physiology
1966
Alginic Acid Metabolism in Bacteria
1962
A small, unstable RNA molecule of Escherichia coli: spot 42 RNA
1979
Unique insertion site of Tn7 in the E. coli chromosome
1982 StandoutNatureNobel
Yeast recombination: the association between double-strand gap repair and crossing-over.
1983 StandoutNobel
Cloning yeast telomeres on linear plasmid vectors
1982 StandoutNobel
Effects of Amino Acid Components of Yeast Extract on the Growth of Tobacco Tissue in Vitro.
1960
COORDINATE REPRESSION OF THE SYNTHESIS OF FOUR HISTIDINE BIOSYNTHETIC ENZYMES BY HISTIDINE
1959
Nucleotide sequence of bacteriophage φX174 DNA
1977 StandoutNatureNobel
Works of H. E. Umbarger being referenced
OPERATOR CONSTITUTIVE MUTATIONS IN THE LEUCINE OPERON OF SALMONELLA TYPHIMURIUM
1969
α-Isopropylmalate Synthase from Salmonella typhimurium
1969
Intracellular Regulatory Mechanisms
1964 Science
Effect of Isoleucine, Valine, or Leucine Starvation on the Potential for Formation of the Branched-Chain Amino Acid Biosynthetic Enzymes
1973
Isoleucine and Valine Metabolism in Escherichia coli
1961
Biosynthesis of Branched-Chain Amino Acids in Yeast: Regulation of Leucine Biosynthesis in Prototrophic and Leucine Auxotrophic Strains
1968
The Biosynthesis of Leucine. II. The Enzymic Isomerization of β-Carboxy-β-Hydroxyisocaproate and α-Hydroxy-β-Carboxyisocaproate*
1963
Regulation of Branched-Chain Amino Acid Biosynthesis in Salmonella typhimurium : Isolation of Regulatory Mutants
1969
THREONINE DEAMINATION IN ESCHERICHIA COLI II
1957
Amino Acid Biosynthesis and its Regulation
1978
Threonine Deaminase from Bacillus subtilis
1970
CONTROL OF ISOLEUCINE, VALINE, AND LEUCINE BIOSYNTHESIS, I. MULTI-VALENT REPRESSION
1962
ISOLEUCINE AND VALINE METABOLISM OF ESCHERICHIA COLI
1951
Biosynthesis of branched-chain amino acids in yeast: effect of carbon source on leucine biosynthetic enzymes
1975
In vitro synthesis of beta-galactosidase with ilv-lac fusion deoxyribonucleic acid as template
1977
Nucleotide sequence of ilvGEDA operon attenuator region of Escherichia coli.
1980
ISOLEUCINE AND VALINE METABOLISM IN ESCHERICHIA COLI XI. K-12
1962
Isoleucine and Valine Metabolism in Escherichia coli XXI. Mutations Affecting Derepression and Valine Resistance
1973
Biosynthesis of Branched-Chain Amino Acids in Yeast: Regulation of Synthesis of the Enzymes of Isoleucine and Valine Biosynthesis
1969
Regulation of Biosynthetic Pathways
1962
Polarity and the regulation of the ilv gene cluster in Escherichia coli strain K-12
1976
Biosynthesis of Branched-Chain Amino Acids in Yeast: Correlation of Biochemical Blocks and Genetic Lesions in Leucine Auxotrophs
1968
Evidence for a Negative-Feedback Mechanism in the Biosynthesis of Isoleucine
1956 Science
The Effects of Analogues of Threonine and of Isoleucine on the Properties of Threonine Deaminase
1963
ISOLEUCINE AND VALINE METABOLISM IN ESCHERICHIA COLI
1953
Control of isoleucine, valine and leucine biosynthesis
1964
Isoleucine and Valine Metabolism of Escherichia coli XVI. Pattern of Multivalent Repression in Strain K-12
1968
Acetohydroxy acid synthase I of Escherichia coli: purification and properties
1979
Regulation of Amino Acid Metabolism
1969
Evidence for Two Distinct Enzyme Systems Forming Acetolactate in Aerobacter aerogenes
1959
Specificity of the stimulation of in vitro ribonucleic acid synthesis by guanosine 5′-diphosphate 3′-diphosphate
1975
Physical characterization of ilv-lac fusions
1979
THREONINE DEAMINATION IN ESCHERICHIA COLI I
1956
THE NUTRITIONAL REQUIREMENTS OF THREONINELESS MUTANTS OF ESCHERICHIA COLI
1953
Mutations affecting the formation of acetohydroxy acid synthase II in Escherichia coli K-12
1979
BIOSYNTHESIS OF SERINE IN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM
1963
The Biosynthesis of Leucine. I. The Accumulation of β-Carboxy-β-Hydroxyisocaproate by Leucine Auxotrophs of Salmonella typhimurium and Neurospora crassa*
1963
ISOLEUCINE AND VALINE METABOLISM OF ESCHERICHIA COLI
1951
The Biosynthesis of Leucine. III. The Conversion of α-Hydroxy-β-Carboxyisocaproate to α-Ketoisocaproate*
1963
Feedback Control by Endproduct Inhibition
1961
Isoleucine and Valine Metabolism in Escherichia coli XXII. A Pleiotropic Mutation Affecting Induction of Isomeroreductase Activity
1973
Isoleucine and Valine Metabolism in Escherichia coli. III. A Method for the Quantitative Determination of α-Keto Acid Analogs of Isoleucine and Valine1
1952
Isoleucine and Valine Metabolism in Escherichia coli
1958
Evidence for a Negative-Feedback Mechanism in the Biosynthesis of Isoleucine
1956 Science
Effect of a leu-linked mutation on the valine sensitivity of acetohydroxy acid synthase activity in Escherichia coli
1975
ISOLEUCINE AND VALINE METABOLISM IN ESCHERICHIA COLI V
1955
The requirement for flavine adenine dinucleotide in the formation of acetolactate by Salmonellatyphimurium extracts
1964
THE RÔLE OF α-KETO-β-ETHYLBUTYRIC ACID IN THE BIOSYNTHESIS OF ISOLEUCINE
1951
Expression of the Leucine Operon
1966
Isoleucine and Valine Metabolism in Escherichia coli
1958
Isoleucine and Valine Metabolism of Escherichia coli XV. Biochemical Properties of Mutants Resistant to Thiaisoleucine
1968
Purification and Properties of the Acetohydroxy Acid Isomeroreductase of Salmonella typhimurium
1969