Citation Impact
Citing Papers
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion
2008 StandoutNobel
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
The Prognostic Value of FoxP3+ Tumor-Infiltrating Lymphocytes in Cancer: A Critical Review of the Literature
2012
Control of Foxp3 stability through modulation of TET activity
2016
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Acquisition of Suppressive Function by Activated Human CD4+CD25− T Cells Is Associated with the Expression of CTLA-4 Not FoxP3
2008
Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells
2010
Nanog Is the Gateway to the Pluripotent Ground State
2009 StandoutNobel
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
FOXP3 Promoter Demethylation Reveals the Committed Treg Population in Humans
2008
Association of allergen-specific regulatory T cells with the onset of clinical tolerance to milk protein
2009
CCR7 and its ligands: balancing immunity and tolerance
2008
Two modes of immune suppression by Foxp3+ regulatory T cells under inflammatory or non-inflammatory conditions
2011 StandoutNobel
Natural and Adaptive Foxp3+ Regulatory T Cells: More of the Same or a Division of Labor?
2009
APE1/Ref-1Role in Redox Signaling: Translational Applications of Targeting the Redox Function of the DNA Repair/Redox Protein APE1/Ref-1
2011
Understanding the language of Lys36 methylation at histone H3
2012
Regulation of Innate and Adaptive Immunity by TGFβ
2017
Regulatory T cell defect in APECED patients is associated with loss of naive FOXP3+ precursors and impaired activated population
2010
Transforming Growth Factor-β Signaling in Immunity and Cancer
2019 Standout
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
IL-35-mediated induction of a potent regulatory T cell population
2010
Conserved and divergent paths that regulate self-renewal in mouse and human embryonic stem cells
2004
Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?
2008
Absence of signaling into CD4+ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3+ regulatory T cells
2012
Inducible reprogramming of human T cells into Treg cells by a conditionally active form of FOXP3
2008
Integrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation
2015
Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
2009 StandoutNobel
Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression
2009
Induction of hepatic differentiation in embryonic stem cells by co-culture with embryonic cardiac mesoderm
2003 StandoutNobel
Regulatory T cells: stability revisited
2011
Regulatory T cells: how do they suppress immune responses?
2009 StandoutNobel
How regulatory T cells work
2008 Standout
Generation of germline-competent induced pluripotent stem cells
2007 StandoutNatureNobel
Regulatory T Cells Reinforce Intestinal Homeostasis
2009
Regulatory T Cells: Molecular and Cellular Basis for Immunoregulation
2017
DNA methylation controls Foxp3 gene expression
2008
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Functional Specialization of Interleukin-17 Family Members
2011 Standout
Self-renewal of teratocarcinoma and embryonic stem cells
2004
FOXP3+ regulatory T cells in the human immune system
2010 StandoutNobel
Regulatory T cells mediate specific suppression by depleting peptide–MHC class II from dendritic cells
2019
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation
2009
Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells
2012
Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection
2017
Integrin αvβ8–expressing tumor cells evade host immunity by regulating TGF-β activation in immune cells
2018
Functional Analysis of FOXP3
2008
Therapeutic approaches to allergy and autoimmunity based on FoxP3+ regulatory T-cell activation and expansion
2009 StandoutNobel
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo
2015
TGF-β Activation and Function in Immunity
2013
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
IL-17–producing human peripheral regulatory T cells retain suppressive function
2009
Genetic and epigenetic basis of Treg cell development and function: from a FoxP3‐centered view to an epigenome‐defined view of natural Treg cells
2014 StandoutNobel
Roles of regulatory T cells in cancer immunity
2016
Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment
2017
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
Release of Active TGF-β1 from the Latent TGF-β1/GARP Complex on T Regulatory Cells Is Mediated by Integrin β8
2014
Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system
2016 StandoutNobel
Surface Expression of TGFβ Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer
2016
Structural basis of latent TGF-β1 presentation and activation by GARP on human regulatory T cells
2018 Science
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro
2005 StandoutNobel
Following the Path of the Virus: The Exploitation of Host DNA Repair Mechanisms by Retroviruses
2006
Processing of Damaged DNA Ends for Double-Strand Break Repair in Mammalian Cells
2012
CD49d provides access to “untouched” human Foxp3+ Treg free of contaminating effector cells
2008
Reactivation of the Paternal X Chromosome in Early Mouse Embryos
2004 StandoutScienceNobel
Controversies concerning thymus‐derived regulatory T cells: fundamental issues and a new perspective
2015
Human memory FOXP3+Tregs secrete IL-17 ex vivo and constitutively express the TH17 lineage-specific transcription factor RORγt
2009
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
2010 Standout
Human CD4+CD25+Foxp3+ Regulatory T Cells Do Not Constitutively Express IL-35
2008
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
2008
Conditional stability of T cells
2010 StandoutNatureNobel
Blocking immunosuppression by human Tregs in vivo with antibodies targeting integrin αVβ8
2017
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Platelets subvert T cell immunity against cancer via GARP-TGFβ axis
2017
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Human blood T fr cells are indicators of ongoing humoral activity not fully licensed with suppressive function
2017
Endothelial Progenitor Cells
2004 Standout
Engagement of distinct epitopes on CD 43 induces different co‐stimulatory pathways in human T cells
2016
Spatial distribution and function of T follicular regulatory cells in human lymph nodes
2018
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
2009 StandoutNobel
GARP regulates the bioavailability and activation of TGFβ
2012
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Differentiation of Effector CD4 T Cell Populations
2010 Standout
Regulatory T cells in inflammatory skin disease: from mice to humans
2019
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel
Works of H. E. Ramsey being referenced
Induction of FOXP3 expression in naive human CD4+FOXP3− T cells by T-cell receptor stimulation is transforming growth factor-β–dependent but does not confer a regulatory phenotype
2007
CD4+FoxP3+ regulatory T cells confer infectious tolerance in a TGF-β–dependent manner
2008
The human set and transposase domain protein Metnase interacts with DNA Ligase IV and enhances the efficiency and accuracy of non-homologous end-joining
2008
Endothelial induction of the T-cell chemokine CCL21 in T-cell autoimmune diseases
2003
The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair
2005
The IL-17 cytokine family members are inhibitors of human hematopoietic progenitor proliferation
2006
The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression
2002
GARP (LRRC32) is essential for the surface expression of latent TGF-β on platelets and activated FOXP3 + regulatory T cells
2009
The homeoprotein Hex is required for hemangioblast differentiation
2003