Citation Impact
Citing Papers
Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity
2008 StandoutNobel
MAP-1 is a mitochondrial effector of Bax
2005
Hypoxia prevents etoposide-induced DNA damage in cancer cells through a mechanism involving hypoxia-inducible factor 1
2009
Dendritic Cell Targeting of Survivin Protein in a Xenogeneic Form Elicits Strong CD4+ T Cell Immunity to Mouse Survivin
2006 StandoutNobel
Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival
2014 StandoutNobel
A Combination of Chemoimmunotherapies Can Efficiently Break Self-Tolerance and Induce Antitumor Immunity in a Tolerogenic Murine Tumor Model
2007 StandoutNobel
Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1α
2010
Hyaluronic Acid Hydrogels for Biomedical Applications
2011 Standout
Effects of cisplatin and amphotericin B on DNA adduct formation and toxicity in malignant glioma and normal tissues in rat
1997
Bax conformational change is a crucial step for PUMA-mediated apoptosis in human leukemia
2003
Survivin antisense compound inhibits proliferation and promotes apoptosis in liver cancer cells
2005
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
Cisplatin: mode of cytotoxic action and molecular basis of resistance
2003 Standout
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Bcl-xES, a BH4- and BH2-containing antiapoptotic protein, delays Bax oligomer formation and binds Apaf-1, blocking procaspase-9 activation
2004
Cancer Metastasis: Building a Framework
2006 Standout
The emerging role of lncRNAs in cancer
2015 Standout
The resurgence of platinum-based cancer chemotherapy
2007 Standout
Hyaluronan: from extracellular glue to pericellular cue
2004 Standout
Control and utilization of ruthenium and rhodium metal complex excited states for photoactivated cancer therapy
2014
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
Hypoxia-Inducible Erythropoietin Signaling in Squamous Dysplasia and Squamous Cell Carcinoma of the Uterine Cervix and Its Potential Role in Cervical Carcinogenesis and Tumor Progression
2003
Neuroblastoma: biological insights into a clinical enigma
2003 Standout
Caspase activation and apoptosis in response to proteasome inhibitors
2005
Elucidation of some Bax conformational changes through crystallization of an antibody–peptide complex
2006
Principles of bioactive lipid signalling: lessons from sphingolipids
2008 Standout
Mechanisms of Disease: mitochondria as new therapeutic targets in diabetic neuropathy
2006
Transient receptor potential channels: targeting pain at the source
2008 StandoutNobel
An Anti-apoptotic Viral Protein That Recruits Bax to Mitochondria
2004
Involvement of Brca2 in DNA Repair
1998 StandoutNobel
The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions
2002
Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases
2011
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
2009 Standout
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Nanoparticle-mediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance
2009
Apop-1, a Novel Protein Inducing Cyclophilin D-dependent but Bax/Bak-related Channel-independent Apoptosis
2006 StandoutNobel
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Matching targets for selective cancer therapy
2003
Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways
2011
Bax Forms an Oligomer via Separate, Yet Interdependent, Surfaces
2010
Anti-apoptotic role of HIF-1 and AP-1 in paclitaxel exposed breast cancer cells under hypoxia
2010
Cationic, linear Au(i) N-heterocyclic carbene complexes: synthesis, structure and anti-mitochondrial activity
2006
Apoptosis
2002 Standout
Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
2003
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Enhanced Phagocytosis through Inhibition of de Novo Ceramide Synthesis
2003 StandoutNobel
Repression of the Long Noncoding RNA-LET by Histone Deacetylase 3 Contributes to Hypoxia-Mediated Metastasis
2013
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
2013 Standout
Neuroblastoma
2007 Standout
Dysregulation of apoptosis genes in hematopoietic malignancies
2002
Regulation of Multidrug Resistance in Cancer Cells by Hyaluronan
2003
Is Cisplatin-Induced Cell Death Always Produced by Apoptosis?
2001
Targeting Immunosupportive Cancer Therapies: Accentuate the Positive, Eliminate the Negative
2007 StandoutNobel
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
The BCL-2 protein family: opposing activities that mediate cell death
2007 Standout
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
2006 Standout
BIM-Mediated Membrane Insertion of the BAK Pore Domain Is an Essential Requirement for Apoptosis
2013
Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
1995
Anemia of Chronic Disease
2005 Standout
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
2012 StandoutNobel
Negative regulation of mitochondrial VDAC channels by C-Raf kinase
2002
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Bcl-2 inhibits chemotherapy-induced apoptosis in neuroblastoma.
1994
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
The Pathophysiology of Mitochondrial Cell Death
2004 StandoutScience
BH3-only proteins — evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death
2002
Inhibition of Bax-Induced CytochromecRelease from Neural Cell and Brain Mitochondria by Dibucaine and Propranolol
2003
Increased Frequency of Aberrations in the p53/MDM2/p14ARF Pathway in Neuroblastoma Cell Lines Established at Relapse
2006
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
2016 Standout
Apoptosis: A Review of Programmed Cell Death
2007 Standout
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Germinal center-derived signals act with Bcl-2 to decrease apoptosis and increase clonogenicity of drug-treated human B lymphoma cells.
1997
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
2011 StandoutNobel
Induction of Tumor Cell Apoptosis In Vivo Increases Tumor Antigen Cross-Presentation, Cross-Priming Rather than Cross-Tolerizing Host Tumor-Specific CD8 T Cells
2003
Mussel-Inspired Surface Chemistry for Multifunctional Coatings
2007 StandoutScience
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Functional Nanomaterials for Phototherapies of Cancer
2014 Standout
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
N-Heterocyclic Carbenes in Late Transition Metal Catalysis
2009 Standout
The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
Interleukin 7-dependent B lymphocyte precursor cells are ultrasensitive to apoptosis.
1994
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and -Independent Mechanisms and Contributes to Drug Resistance
2004
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
2003
Newcomers in the process of mitochondrial permeabilization
2005
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Enhanced sensitivity of human oral carcinomas to induction of apoptosis by selenium compounds: involvement of mitogen-activated protein kinase and Fas pathways.
2001
Current Understanding of the Molecular Actions of Vitamin D
1998
Organoselenium and Organotellurium Compounds: Toxicology and Pharmacology
2004 Standout
TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB
1996 StandoutScience
Works of Guy Makin being referenced
Hypoxic human cancer cells are sensitized to BH-3 mimetic–induced apoptosis via downregulation of the Bcl-2 protein Mcl-1
2011
Apoptosis and cancer chemotherapy
2001
The cellular adaptations to hypoxia as novel therapeutic targets in childhood cancer
2008
Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate
2001
Targeting apoptosis in cancer chemotherapy
2002
Apoptosis and cancer chemotherapy
2000
Recent advances in understanding apoptosis: new therapeutic opportunities in cancer chemotherapy
2003
Apoptosis and cancer chemotherapy
2001
Principles of chemotherapy
2014
Chronic hypoxia promotes hypoxia-inducible factor-1α–dependent resistance to etoposide and vincristine in neuroblastoma cells
2006
Target cell metabolism of 1,25-dihydroxyvitamin D3 to calcitroic acid. Evidence for a pathway in kidney and bone involving 24-oxidation
1989