Citation Impact
Citing Papers
PtdIns(3,4,5) P 3-Dependent Activation of the mTORC2 Kinase Complex
2015
2017
PIKfyve, a Class III Lipid Kinase, Is Required for TLR-Induced Type I IFN Production via Modulation of ATF3
2014
Protein misfolding disorders and macroautophagy
2010
APP controls the formation of PI(3,5)P2 vesicles through its binding of the PIKfyve complex
2015
Latrophilins Function as Heterophilic Cell-adhesion Molecules by Binding to Teneurins
2013 StandoutNobel
Epidemiology and causes of preterm birth
2008 Standout
Phosphatidylinositol 4-Kinases Are Required for Autophagic Membrane Trafficking
2012
The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation
2018 StandoutNobel
PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome
2010
Autophagy in infection, inflammation and immunity
2013 Standout
Flt3 Signaling-Dependent Dendritic Cells Protect against Atherosclerosis
2011 StandoutNobel
Dynamic control of neuroexocytosis by phosphoinositides in health and disease
2010
The role of autophagy in neurodegenerative disease
2013 Standout
Kruppel-Like Factor 15 Modulates Renal Interstitial Fibrosis by ERK/MAPK and JNK/MAPK Pathways Regulation
2013 Standout
Low-Density Lipoprotein Receptor-Related Protein-1 Mediates Endocytic Clearance of Tissue Inhibitor of Metalloproteinases-1 and Promotes Its Cytokine-Like Activities
2014 StandoutNobel
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
2012 Standout
Ageing as a risk factor for neurodegenerative disease
2019 Standout
Effective gene expression prediction from sequence by integrating long-range interactions
2021 StandoutNobel
Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk
2018
Ten-m3 Is Required for the Development of Topography in the Ipsilateral Retinocollicular Pathway
2012
The use of high‐dimensional biology (genomics, transcriptomics, proteomics, and metabolomics) to understand the preterm parturition syndrome
2006
Lysosomal Ion Channels as Decoders of Cellular Signals
2018
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Amyotrophic lateral sclerosis
2017
The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm
2017 Standout
Drug repurposing: progress, challenges and recommendations
2018 Standout
Phosphatidylinositol‐3,5‐Bisphosphate: No Longer the Poor PIP2
2011
Genes and Abdominal Aortic Aneurysm
2010
Glycogen synthase kinase 3β inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism
2017 StandoutNobel
Autophagy modulation as a potential therapeutic target for diverse diseases
2012 Standout
DNA methylation-based biomarkers and the epigenetic clock theory of ageing
2018 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Endosome maturation
2011 Standout
Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice
2014
The PI3K Pathway in Human Disease
2017 Standout
Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
2020 Standout
Cerebral white matter hyperintensities on MRI and acceleration of epigenetic aging: the atherosclerosis risk in communities study
2017
A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation
2016
The role of PI3P phosphatases in the regulation of autophagy
2010
Yeast and mammalian autophagosomes exhibit distinct phosphatidylinositol 3-phosphate asymmetries
2014 StandoutNobel
Genetics of abdominal aortic aneurysm
2013
Phosphoinositides: multipurpose cellular lipids with emerging roles in cell death
2019
Cellular senescence: from physiology to pathology
2014 Standout
Atg9 Vesicles Recruit Vesicle-tethering Proteins Trs85 and Ypt1 to the Autophagosome Formation Site
2012 StandoutNobel
Amyotrophic Lateral Sclerosis Pathogenesis: A Journey Through the Secretory Pathway
2010
Protein clearing pathways in ALS.
2011
Circulating Markers of Abdominal Aortic Aneurysm Presence and Progression
2008
Aortic Aneurysms
2008
LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin
2012
pH of endophagosomes controls association of their membranes with Vps34 and PtdIns(3)P levels
2017
Embryological-Origin–Dependent Differences in Homeobox Expression in Adult Aorta
2013
Phosphatidylinositol 3,5‐bisphosphate: Low abundance, high significance
2013
FIG4 is a hepatitis C virus particle-bound protein implicated in virion morphogenesis and infectivity with cholesteryl ester modulation potential
2015
Klf15 Deficiency Is a Molecular Link Between Heart Failure and Aortic Aneurysm Formation
2010
Multiple Sclerosis
2018 Standout
The signaling lipid PI(3,5)P2stabilizes V1–Vosector interactions and activates the V-ATPase
2014
Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19
2021 StandoutNobel
2014
The Lipid Kinase PIKfyve Coordinates the Neutrophil Immune Response through the Activation of the Rac GTPase
2017
Canonical and non-canonical autophagy: variations on a common theme of self-eating?
2011
Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma
2017
Th Cell Diversity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis
2015
Vascular Smooth Muscle Cells in Atherosclerosis
2016 Standout
Identify potential drugs for cardiovascular diseases caused by stress-induced genes in vascular smooth muscle cells
2016
Pathogenesis of Abdominal Aortic Aneurysms: MicroRNAs, Proteases, Genetic Associations
2013
Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion
2018 Standout
PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1
2014
The Role of Atg Proteins in Autophagosome Formation
2011 StandoutNobel
Works of Guy M. Lenk being referenced
Whole genome expression profiling reveals a significant role for immune function in human abdominal aortic aneurysms
2007
Regional expression of HOXA4 along the aorta and its potential role in human abdominal aortic aneurysms
2011
Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)P2 phosphatase FIG4
2011
Analysis of positional candidate genes in the AAA1 susceptibility locus for abdominal aortic aneurysms on chromosome 19
2011
Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2
2009
PtdIns(3,5)P2and autophagy in mouse models of neurodegeneration
2010
Yunis-Varón Syndrome Is Caused by Mutations in FIG4, Encoding a Phosphoinositide Phosphatase
2013
Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration
2012
Congenital CNS Hypomyelination in theFig4Null Mouse Is Rescued by Neuronal Expression of the PI(3,5)P2PhosphataseFig4
2011
Genome‐Wide Approach to Finding Abdominal Aortic Aneurysm Susceptibility Genes in Humans
2006
Pathogenic Mechanism of the FIG4 Mutation Responsible for Charcot-Marie-Tooth Disease CMT4J
2011
Integration of expression profiles and genetic mapping data to identify candidate genes in intracranial aneurysm
2007
Role of the phosphoinositide phosphatase FIG4 gene in familial epilepsy with polymicrogyria
2014
Genetic predisposition for preterm PROM: Results of a large candidate-gene association study of mothers and their offspring
2005
Binding Sites for ETS Family of Transcription Factors Dominate the Promoter Regions of Differentially Expressed Genes in Abdominal Aortic Aneurysms
2009
In vivo, Pikfyve generates PI(3,5)P 2 , which serves as both a signaling lipid and the major precursor for PI5P
2012